Missouri

$58+ Cheap flights from San Diego (SAN) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Jul 19 — Jul 261
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Cheap flight deals from San Diego to Missouri

Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated July 14, 2025.

Round-trip from

$154
(FlightHub)

One-way from

$58
(eDestinos)

Popular in

March

Cheapest in

September

Average price

$319

Good round-trip deal

$396 or less

Good one-way deal

$188 or less
From San Diego to Missouri
One-way flight from San Diego to Missouri
Highest demand for flights based on searches. 4% potential increase in price ($13 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in July 2025
Price to beat on a round-trip flight from San Diego to Missouri.
Price to beat on a one-way flight from San Diego to Missouri.

Find flight deals from San Diego to Missouri

Cheapest flights from San Diego to Missouri
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2025.

This FlightHub deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:15 amSAN - MCI
1 stop5h 45mSpirit Airlines
Sun 9/282:55 pmMCI - SAN
1 stop18h 29mSpirit Airlines
Deal found 7/14$187
This Priceline deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/229:11 pmSAN - STL
1 stop10h 00mFrontier
Sun 8/247:54 pmSTL - SAN
1 stop5h 58mFrontier
Deal found 7/12$194
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:52 pmSAN - MCI
1 stop5h 50mUnited Airlines
Mon 9/18:30 amMCI - SAN
1 stop7h 24mUnited Airlines
Deal found 7/14$233
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2910:50 amSAN - MCI
1 stop8h 33mAmerican Airlines
Tue 9/22:51 pmMCI - SAN
1 stop6h 47mAmerican Airlines
Deal found 7/13$241
This Mytrip deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/177:01 pmSAN - SGF
1 stop15h 03mMultiple Airlines
Fri 8/229:57 pmSGF - SAN
1 stop11h 24mMultiple Airlines
Deal found 7/13$246
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:45 amSAN - MCI
1 stop8h 48mDelta
Fri 1/26:13 pmMCI - SAN
1 stop7h 36mDelta
Deal found 7/13$249
This Justfly.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/166:25 amSAN - MCI
1 stop9h 58mFrontier
Mon 7/218:01 pmMCI - SAN
1 stop17h 09mFrontier
Deal found 7/13$256
This Orbitz deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/116:15 amSAN - MCI
1 stop5h 22mMultiple Airlines
Wed 8/137:20 pmMCI - SAN
1 stop5h 42mMultiple Airlines
Deal found 7/12$259
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/203:10 pmSAN - MCI
Nonstop3h 10mSouthwest
Sat 8/236:10 amMCI - SAN
1 stop5h 00mSouthwest
Deal found 7/13$265
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1110:45 pmSAN - SGF
1 stop8h 59mAmerican Airlines
Mon 8/186:01 pmSGF - SAN
1 stop7h 22mAmerican Airlines
Deal found 7/14$269
This Mytrip deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/271:34 pmSAN - STL
2 stops18h 06mSpirit Airlines
Sun 9/282:26 pmSTL - SAN
3 stops33h 47mSpirit Airlines
Deal found 7/14$269
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:30 pmSAN - STL
1 stop5h 30mSouthwest
Mon 12/153:15 pmSTL - SAN
Nonstop4h 00mSouthwest
Deal found 7/14$271

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2025.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.

Fly from

San Diego

Fly to

Missouri

Route

Depart

Return

Price

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Thu 9/25

6:15 am-2:00 pm

1 stop5h 45m

Kansas City

Sun 9/28

2:55 pm-7:24 am

1 stop18h 29m

$187

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 8/22

9:11 pm-9:11 am

1 stop10h 00m

Lambert-St Louis

Sun 8/24

7:54 pm-11:52 pm

1 stop5h 58m

$194

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Sat 8/30

12:52 pm-8:42 pm

1 stop5h 50m

Kansas City

Mon 9/1

8:30 am-1:54 pm

1 stop7h 24m

$233

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Fri 8/29

10:50 am-9:23 pm

1 stop8h 33m

Kansas City

Tue 9/2

2:51 pm-7:38 pm

1 stop6h 47m

$241

San DiegoSpringfield

SAN - SGF

SANSGF

San Diego

Sun 8/17

7:01 pm-12:04 pm

1 stop15h 03m

Springfield-Branson

Fri 8/22

9:57 pm-7:21 am

1 stop11h 24m

$246

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Thu 7/31

5:00 pm-12:21 am

1 stop5h 21m

Kansas City

Mon 8/4

5:41 pm-11:29 pm

1 stop7h 48m

$258

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Mon 8/11

6:15 am-1:37 pm

1 stop5h 22m

Kansas City

Wed 8/13

7:20 pm-11:02 pm

1 stop5h 42m

$259

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Wed 8/20

3:10 pm-8:20 pm

Nonstop3h 10m

Kansas City

Sat 8/23

6:10 am-9:10 am

1 stop5h 00m

$265

San DiegoSpringfield

SAN - SGF

SANSGF

San Diego

Mon 8/11

10:45 pm-9:44 am

1 stop8h 59m

Springfield-Branson

Mon 8/18

6:01 pm-11:23 pm

1 stop7h 22m

$269

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Thu 12/11

1:30 pm-9:00 pm

1 stop5h 30m

Lambert-St Louis

Mon 12/15

3:15 pm-5:15 pm

Nonstop4h 00m

$271

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/12

Showing 1-10 of 38 results
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Best time to book a flight from San Diego to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Missouri

What is the cheapest month to book a flight from San Diego to Missouri?

Currently, August is the cheapest month in which you can book a flight from San Diego to Missouri (average of $311). Flying from San Diego to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to MO?

Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 14, 2025.

When flying from San Diego to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from San Diego to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 14, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest, and Delta from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
8.0
Very good

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to Missouri?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Missouri. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How popular is this San Diego to Missouri flight route?

  • What are the cheapest airlines to fly from San Diego to Missouri one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $58. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from San Diego to Missouri for a low price.

  • What are the most popular routes from San Diego to Missouri?

  • What are the cheapest flights from San Diego to Missouri?

    The cheapest flight price from San Diego to Missouri is $72. On average you can expect to pay $325. The most popular route, (San Diego - Lambert-St Louis), can usually be booked for $268.

  • Can I find deals for flights from San Diego to Missouri that include hotel bookings?

    Yes. In addition to deals on San Diego to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Missouri.

  • Can I find deals for business class flights from San Diego to Missouri?

    Yes. Cheapflights offers flight deals from San Diego to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Missouri?

    Currently, August is the cheapest month in which you can book a flight from San Diego to Missouri (average of $311). Flying from San Diego to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from San Diego to Missouri

Discover the top 7 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$113Average$265FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$116Average$231FlexibilityNo cancel feeOn-time65%
DeltaCheapest$184Average$309FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$433FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$237Average$379FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$273Average$713FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$274Average$479FlexibilityNo cancel feeOn-time63%

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