$91+ Cheap flights from San Diego (SAN) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MCI
Jul 27 — Aug 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to MissouriExplore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/64:28 pm
SAN
- SGF
1 stop25h 41m
Multiple Airlines
Mon 8/108:59 pm
SGF
- SAN
1 stop20h 44m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$216
This Frontier deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:25 am
SAN
- STL
1 stop10h 50m
Frontier
Tue 10/138:10 pm
STL
- SAN
1 stop5h 49m
Frontier
Deal found 6/25![Frontier logo]()
$248
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:25 am
SAN
- STL
1 stop10h 58m
Frontier
Tue 8/117:03 pm
STL
- SAN
1 stop21h 05m
Frontier
Deal found 6/22![Frontier logo]()
$253
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:25 am
SAN
- STL
1 stop10h 58m
Frontier
Fri 7/178:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/24![Frontier logo]()
$258
This Mytrip deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:10 am
SAN
- STL
1 stop7h 13m
Frontier
Thu 8/138:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/22![Frontier logo]()
$259
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Wed 7/297:03 pm
STL
- SAN
1 stop27h 03m
Frontier
Deal found 6/24![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Mon 7/274:57 pm
STL
- SAN
2 stops28h 04m
Frontier
Deal found 6/23![Frontier logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:57 am
SAN
- SGF
1 stop24h 25m
Multiple Airlines
Sun 9/201:12 pm
SGF
- SAN
1 stop21h 50m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$268
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:35 am
SAN
- STL
1 stop6h 21m
Frontier
Sun 7/127:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/24![Frontier logo]()
$268
This Trip.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Sun 8/28:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/23![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sun 8/97:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/26![Frontier logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Sun 8/96:34 pm
STL
- SAN
2 stops26h 26m
Frontier
Deal found 6/22![Frontier logo]()
$275
Best flights from San Diego to MissouriDiscover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
Discover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:30 pm
SAN
- STL
1 stop9h 50m
Delta
Tue 8/1812:52 pm
STL
- SAN
1 stop8h 43m
Delta
Deal found 6/22![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1910:45 pm
SAN
- COU
1 stop9h 17m
American Airlines
Sat 7/257:26 pm
COU
- SAN
1 stop6h 33m
American Airlines
Deal found 6/23![American Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:40 pm
SAN
- COU
1 stop9h 36m
United Airlines
Tue 8/186:15 am
COU
- SAN
2 stops9h 29m
United Airlines
Deal found 6/22![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:20 am
SAN
- MCI
2 stops6h 25m
Southwest
Sun 11/86:45 am
MCI
- SAN
1 stop5h 15m
Southwest
Deal found 6/22![Southwest logo]()
$329
This Alaska Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:37 am
SAN
- MCI
1 stop10h 22m
Alaska Airlines
Wed 8/261:34 pm
MCI
- SAN
1 stop9h 20m
Alaska Airlines
Deal found 6/26![Alaska Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:30 am
SAN
- SGF
1 stop7h 54m
United Airlines
Wed 9/24:58 pm
SGF
- SAN
1 stop6h 27m
United Airlines
Deal found 6/22![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:56 am
SAN
- SGF
1 stop9h 12m
Delta
Wed 9/163:19 pm
SGF
- SAN
1 stop8h 01m
Delta
Deal found 6/24![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:05 pm
SAN
- MCI
1 stop6h 10m
Southwest
Mon 8/177:20 am
MCI
- SAN
Nonstop3h 15m
Southwest
Deal found 6/22![Southwest logo]()
$336
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:00 am
SAN
- IRK
1 stop11h 15m
Multiple Airlines
Sat 7/119:45 am
IRK
- SAN
1 stop12h 44m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:13 am
SAN
- SGF
1 stop8h 21m
United Airlines
Wed 10/75:30 am
SGF
- SAN
1 stop5h 35m
United Airlines
Deal found 6/26![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:15 am
SAN
- COU
1 stop9h 37m
American Airlines
Wed 7/155:19 pm
COU
- SAN
1 stop8h 40m
American Airlines
Deal found 6/26![American Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:00 am
SAN
- SGF
1 stop8h 55m
United Airlines
Mon 9/75:30 am
SGF
- SAN
1 stop5h 35m
United Airlines
Deal found 6/24![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:40 pm
SAN
- MCI
Nonstop3h 05m
Southwest
Sat 10/311:45 pm
MCI
- SAN
1 stop4h 40m
Southwest
Deal found 6/23![Southwest logo]()
$366
This Alaska Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:35 pm
SAN
- MCI
1 stop17h 46m
Alaska Airlines
Sat 8/156:02 am
MCI
- SAN
2 stops14h 18m
Alaska Airlines
Deal found 6/27![Alaska Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:13 am
SAN
- SGF
1 stop6h 23m
United Airlines
Sat 10/245:30 am
SGF
- SAN
2 stops8h 05m
United Airlines
Deal found 6/25![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:55 pm
SAN
- STL
1 stop6h 15m
Southwest
Thu 8/138:35 am
STL
- SAN
Nonstop3h 45m
Southwest
Deal found 6/22![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:59 pm
SAN
- SGF
1 stop9h 18m
American Airlines
Mon 8/37:40 pm
SGF
- SAN
1 stop6h 19m
American Airlines
Deal found 6/25![American Airlines logo]()
$421
This Alaska Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:59 pm
SAN
- MCI
2 stops13h 39m
Alaska Airlines
Sun 9/272:53 pm
MCI
- SAN
1 stop7h 31m
Alaska Airlines
Deal found 6/22![Alaska Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:30 am
SAN
- STL
Nonstop3h 40m
Southwest
Sat 8/18:50 pm
STL
- SAN
Nonstop3h 50m
Southwest
Deal found 6/23![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:15 pm
SAN
- COU
1 stop6h 40m
United Airlines
Mon 9/1411:17 am
COU
- SAN
2 stops10h 45m
United Airlines
Deal found 6/24![United Airlines logo]()
$357
This Alaska Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:15 am
SAN
- MCI
1 stop15h 44m
Alaska Airlines
Thu 11/127:01 am
MCI
- SAN
2 stops11h 32m
Alaska Airlines
Deal found 6/24![Alaska Airlines logo]()
$436
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:25 pm
SAN
- STL
1 stop5h 30m
Southwest
Sun 10/114:10 pm
STL
- SAN
1 stop6h 20m
Southwest
Deal found 6/26![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:13 am
SAN
- SGF
1 stop6h 23m
United Airlines
Tue 10/135:30 am
SGF
- SAN
2 stops8h 05m
United Airlines
Deal found 6/22![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:40 am
SAN
- MCI
2 stops8h 30m
Southwest
Sat 7/253:45 pm
MCI
- SAN
2 stops8h 15m
Southwest
Deal found 6/23![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:38 am
SAN
- COU
2 stops8h 52m
United Airlines
Mon 11/163:16 pm
COU
- SAN
2 stops9h 14m
United Airlines
Deal found 6/25![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 pm
SAN
- MCI
Nonstop3h 10m
Southwest
Mon 9/216:35 am
MCI
- SAN
1 stop5h 20m
Southwest
Deal found 6/24![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:07 pm
SAN
- JLN
1 stop5h 37m
United Airlines
Mon 7/131:57 pm
JLN
- SAN
2 stops11h 57m
United Airlines
Deal found 6/24![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:10 pm
SAN
- STL
1 stop7h 25m
Southwest
Sun 9/278:25 am
STL
- SAN
Nonstop3h 45m
Southwest
Deal found 6/23![Southwest logo]()
$413
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:30 am
SAN
- STL
1 stop8h 04m
United Airlines
Tue 8/181:36 pm
STL
- SAN
2 stops9h 09m
United Airlines
Deal found 6/22![United Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:07 pm
SAN
- STL
1 stop5h 24m
United Airlines
Mon 8/3112:59 pm
STL
- SAN
2 stops8h 56m
United Airlines
Deal found 6/26![United Airlines logo]()
$402
Last-minute flights from San Diego to MissouriDiscover last-minute flight deals from San Diego to Missouri. Data last updated June 27, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Missouri. Data last updated June 27, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:43 am
SAN
- STL
1 stop7h 08m
Frontier
Tue 7/148:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/24![Frontier logo]()
$283
This Expedia deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:25 am
SAN
- STL
1 stop10h 58m
Frontier
Tue 7/148:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/23![Frontier logo]()
$278
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:35 am
SAN
- STL
1 stop6h 21m
Frontier
Sun 7/127:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/24![Frontier logo]()
$268
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sun 7/198:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/24![Frontier logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:46 pm
SAN
- MCI
2 stops39h 14m
Frontier
Mon 8/34:32 pm
MCI
- SAN
1 stop23h 36m
Frontier
Deal found 6/23![Frontier logo]()
$280
This Super.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:03 pm
SAN
- MCI
1 stop22h 44m
Frontier
Mon 7/204:32 pm
MCI
- SAN
1 stop5h 34m
Frontier
Deal found 6/24![Frontier logo]()
$281
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:25 am
SAN
- STL
1 stop10h 58m
Frontier
Fri 7/178:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/24![Frontier logo]()
$258
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:32 pm
SAN
- MCI
1 stop5h 51m
American Airlines
Tue 7/216:01 am
MCI
- SAN
1 stop4h 50m
American Airlines
Deal found 6/22![American Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Mon 7/274:57 pm
STL
- SAN
2 stops28h 04m
Frontier
Deal found 6/23![Frontier logo]()
$265
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Wed 7/297:03 pm
STL
- SAN
1 stop27h 03m
Frontier
Deal found 6/24![Frontier logo]()
$263
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:25 am
SAN
- STL
1 stop10h 58m
Frontier
Tue 8/47:03 pm
STL
- SAN
1 stop21h 05m
Frontier
Deal found 6/22![Frontier logo]()
$248
This Trip.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Sun 8/28:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/23![Frontier logo]()
$270
One-way flights from San Diego to MissouriSearch for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
Search for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:51 pm
SAN
- MCI
1 stop16h 56m
Frontier
Deal found 6/26![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:59 pm
SAN
- MCI
1 stop17h 03m
Frontier
Deal found 6/23![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 6/24![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/25![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 6/26![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:25 am
SAN
- STL
1 stop10h 50m
Frontier
Deal found 6/25![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:51 pm
SAN
- MCI
1 stop16h 56m
Frontier
Deal found 6/26![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:32 pm
SAN
- MCI
1 stop14h 50m
Frontier
Deal found 6/26![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:32 pm
SAN
- MCI
1 stop14h 50m
Frontier
Deal found 6/23![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:03 pm
SAN
- MCI
1 stop22h 44m
Frontier
Deal found 6/24![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Deal found 6/24![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:40 pm
SAN
- MCI
2 stops21h 07m
Frontier
Deal found 6/24![Frontier logo]()
$113
Find flight deals from San Diego to Missouri
Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated June 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $216 (Kiwi.com) |
One-way from | $91 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $375 |
Good round-trip deal | $336 or less |
Good one-way deal | $205 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 8/14
9:30 pm-9:20 am
1 stop9h 50m
Lambert-St Louis
Tue 8/18
12:52 pm-7:35 pm
1 stop8h 43m
$297
San DiegoColumbia
SAN - COU
SANCOU
San Diego
Sun 7/19
10:45 pm-10:02 am
1 stop9h 17m
Columbia Regional
Sat 7/25
7:26 pm-11:59 pm
1 stop6h 33m
$318
San DiegoColumbia
SAN - COU
SANCOU
San Diego
Tue 8/11
10:40 pm-10:16 am
1 stop9h 36m
Columbia Regional
Tue 8/18
6:15 am-1:44 pm
2 stops9h 29m
$324
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Wed 11/4
9:20 am-5:45 pm
2 stops6h 25m
Kansas City
Sun 11/8
6:45 am-10:00 am
1 stop5h 15m
$329
San DiegoSpringfield
SAN - SGF
SANSGF
San Diego
Sat 8/29
6:30 am-4:24 pm
1 stop7h 54m
Springfield-Branson
Wed 9/2
4:58 pm-9:25 pm
1 stop6h 27m
$329
San DiegoSpringfield
SAN - SGF
SANSGF
San Diego
Fri 9/11
10:56 am-10:08 pm
1 stop9h 12m
Springfield-Branson
Wed 9/16
3:19 pm-9:20 pm
1 stop8h 01m
$329
San DiegoSpringfield
SAN - SGF
SANSGF
San Diego
Wed 9/30
10:13 am-8:34 pm
1 stop8h 21m
Springfield-Branson
Wed 10/7
5:30 am-9:05 am
1 stop5h 35m
$329
San DiegoSpringfield
SAN - SGF
SANSGF
San Diego
Wed 9/2
8:00 am-6:55 pm
1 stop8h 55m
Springfield-Branson
Mon 9/7
5:30 am-9:05 am
1 stop5h 35m
$329
San DiegoSpringfield
SAN - SGF
SANSGF
San Diego
Wed 10/21
10:13 am-6:36 pm
1 stop6h 23m
Springfield-Branson
Sat 10/24
5:30 am-11:35 am
2 stops8h 05m
$334
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Fri 8/14
2:05 pm-10:15 pm
1 stop6h 10m
Kansas City
Mon 8/17
7:20 am-8:35 am
Nonstop3h 15m
$336
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
SAN-MCI
SAN-SGF
SAN-STL
SAN-COU
SAN-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Missouri
SAN-USMO
SAN-MCI
SAN-SGF
SAN-STL
SAN-COU
What is the cheapest month to book a flight from San Diego to Missouri?
Currently, October is the cheapest month in which you can book a flight from San Diego to Missouri (average of $74). Flying from San Diego to Missouri in January is currently the most expensive (average of $214). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to MO?
Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 27, 2026.
One of the essential ways to save on airfare from San Diego to Missouri is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 39% on airfare.
How much does it cost to fly round-trip from San Diego to Missouri?
How far ahead should I book a flight from San Diego to Missouri?
To ensure you get the cheapest price possible for a flight from San Diego to Missouri, you should look to book at least 85 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 27, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for San Diego to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Missouri by cabin class
Find flights from San Diego to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Missouri flights
Browse other San Diego and Missouri flight options. Last updated on June 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Missouri flights
Consider these flights traveling from San Diego to Missouri.
Top 7 airlines flying from San Diego to Missouri
Discover the top 7 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$104 | Average$242 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$138 | Average$345 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$386 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$217 | Average$407 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$232 | Average$443 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$236 | Average$361 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$447 | FlexibilityNo cancel fee | On-time63% |