$81+ Cheap flights from San Diego (SAN) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Jun 12 — Jun 191
Round-trip
1 adult, Economy
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Cheapest flights from San Diego to MissouriExplore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sat 6/68:08 pm
STL
- SAN
1 stop5h 42m
Frontier
Deal found 5/10![Frontier logo]()
$192
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:25 am
SAN
- MCI
1 stop4h 57m
Frontier
Tue 10/132:17 pm
MCI
- SAN
1 stop11h 42m
Frontier
Deal found 5/12![Frontier logo]()
$210
This Expedia deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:25 am
SAN
- STL
1 stop10h 58m
Frontier
Tue 6/167:46 pm
STL
- SAN
1 stop15h 02m
Frontier
Deal found 5/10![Frontier logo]()
$210
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:43 am
SAN
- STL
1 stop7h 08m
Frontier
Wed 6/248:08 pm
STL
- SAN
1 stop15h 01m
Frontier
Deal found 5/10![Frontier logo]()
$211
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:32 pm
SAN
- MCI
1 stop14h 50m
Frontier
Wed 9/162:17 pm
MCI
- SAN
1 stop11h 42m
Frontier
Deal found 5/8![Frontier logo]()
$224
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:36 pm
SAN
- STL
1 stop20h 30m
Frontier
Wed 6/107:03 pm
STL
- SAN
1 stop15h 45m
Frontier
Deal found 5/9![Frontier logo]()
$224
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- MCI
1 stop5h 24m
Frontier
Sat 6/62:34 pm
MCI
- SAN
1 stop11h 16m
Frontier
Deal found 5/10![Frontier logo]()
$230
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- STL
1 stop10h 58m
Frontier
Wed 6/38:08 pm
STL
- SAN
1 stop5h 42m
Frontier
Deal found 5/10![Frontier logo]()
$230
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:43 am
SAN
- STL
1 stop8h 28m
Frontier
Mon 6/157:38 pm
STL
- SAN
1 stop6h 15m
Frontier
Deal found 5/9![Frontier logo]()
$240
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:53 pm
SAN
- MCI
1 stop13h 02m
Frontier
Sun 7/261:45 pm
MCI
- SAN
1 stop21h 20m
Frontier
Deal found 5/11![Frontier logo]()
$241
This Booking.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:53 pm
SAN
- MCI
1 stop13h 02m
Frontier
Sun 8/91:50 pm
MCI
- SAN
1 stop7h 41m
Frontier
Deal found 5/12![Frontier logo]()
$242
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:25 am
SAN
- STL
1 stop6h 24m
Frontier
Wed 7/297:03 pm
STL
- SAN
1 stop26h 28m
Frontier
Deal found 5/8![Frontier logo]()
$242
Best flights from San Diego to MissouriDiscover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
Discover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:55 pm
SAN
- MCI
1 stop4h 35m
Southwest
Mon 6/296:30 pm
MCI
- SAN
1 stop4h 35m
Southwest
Deal found 5/8![Southwest logo]()
$272
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:54 am
SAN
- MCI
1 stop6h 18m
Delta
Mon 7/135:42 pm
MCI
- SAN
1 stop7h 48m
Delta
Deal found 5/10![Delta logo]()
$277
This Alaska Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
SAN
- MCI
1 stop7h 57m
Alaska Airlines
Sat 5/305:52 pm
MCI
- SAN
1 stop8h 15m
Alaska Airlines
Deal found 5/8![Alaska Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:45 pm
SAN
- COU
1 stop9h 16m
American Airlines
Thu 8/66:37 pm
COU
- SAN
1 stop6h 57m
American Airlines
Deal found 5/11![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:00 am
SAN
- MCI
1 stop6h 52m
United Airlines
Sun 8/166:00 am
MCI
- SAN
2 stops7h 35m
United Airlines
Deal found 5/10![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:30 pm
SAN
- MCI
1 stop9h 54m
Delta
Sat 7/254:04 pm
MCI
- SAN
1 stop6h 11m
Delta
Deal found 5/11![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:55 am
SAN
- MCI
1 stop5h 50m
Southwest
Mon 6/155:50 am
MCI
- SAN
1 stop6h 45m
Southwest
Deal found 5/12![Southwest logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:25 am
SAN
- TBN
2 stops29h 25m
Multiple Airlines
Wed 5/272:30 pm
TBN
- SAN
1 stop30h 00m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:15 pm
SAN
- MCI
1 stop9h 31m
Delta
Thu 6/113:55 pm
MCI
- SAN
1 stop5h 21m
Delta
Deal found 5/8![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1910:45 pm
SAN
- COU
1 stop9h 17m
American Airlines
Sat 7/255:19 pm
COU
- SAN
1 stop7h 18m
American Airlines
Deal found 5/12![American Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:15 am
SAN
- MCI
1 stop8h 43m
Delta
Mon 9/77:40 pm
MCI
- SAN
1 stop6h 02m
Delta
Deal found 5/12![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:40 pm
SAN
- STL
1 stop7h 05m
Southwest
Mon 8/34:45 pm
STL
- SAN
2 stops6h 20m
Southwest
Deal found 5/11![Southwest logo]()
$323
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:00 pm
SAN
- SGF
1 stop8h 38m
American Airlines
Wed 9/167:48 pm
SGF
- SAN
1 stop6h 03m
American Airlines
Deal found 5/12![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:00 am
SAN
- SGF
1 stop6h 11m
United Airlines
Sat 8/155:30 am
SGF
- SAN
1 stop5h 35m
United Airlines
Deal found 5/8![United Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:01 pm
SAN
- STL
1 stop5h 40m
Delta
Wed 7/297:55 pm
STL
- SAN
1 stop5h 55m
Delta
Deal found 5/10![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:55 pm
SAN
- MCI
1 stop4h 35m
Southwest
Mon 7/67:10 pm
MCI
- SAN
1 stop6h 05m
Southwest
Deal found 5/12![Southwest logo]()
$348
This Alaska Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:00 am
SAN
- SGF
1 stop6h 26m
Alaska Airlines
Sat 8/19:30 am
SGF
- SAN
1 stop8h 24m
Alaska Airlines
Deal found 5/10![Alaska Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:15 pm
SAN
- MCI
1 stop9h 31m
Delta
Sun 6/73:55 pm
MCI
- SAN
1 stop5h 21m
Delta
Deal found 5/9![Delta logo]()
$298
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:58 pm
SAN
- SGF
1 stop5h 30m
United Airlines
Sat 11/141:41 pm
SGF
- SAN
2 stops9h 04m
United Airlines
Deal found 5/8![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:50 pm
SAN
- MCI
2 stops6h 45m
Southwest
Mon 9/76:20 am
MCI
- SAN
1 stop5h 00m
Southwest
Deal found 5/12![Southwest logo]()
$353
This Alaska Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:00 am
SAN
- SGF
1 stop6h 26m
Alaska Airlines
Tue 6/239:29 am
SGF
- SAN
1 stop8h 25m
Alaska Airlines
Deal found 5/12![Alaska Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:04 pm
SAN
- SGF
1 stop6h 15m
United Airlines
Tue 10/66:25 am
SGF
- SAN
2 stops13h 01m
United Airlines
Deal found 5/13![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:55 pm
SAN
- STL
1 stop4h 55m
Southwest
Sun 6/217:35 pm
STL
- SAN
1 stop5h 35m
Southwest
Deal found 5/12![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:50 pm
SAN
- SGF
1 stop7h 42m
Delta
Sat 11/143:30 pm
SGF
- SAN
1 stop9h 33m
Delta
Deal found 5/8![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:05 am
SAN
- COU
1 stop9h 19m
American Airlines
Sun 6/217:39 pm
COU
- SAN
1 stop6h 20m
American Airlines
Deal found 5/9![American Airlines logo]()
$454
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:25 am
SAN
- TBN
1 stop27h 20m
Multiple Airlines
Sun 5/312:30 pm
TBN
- SAN
2 stops20h 12m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:41 pm
SAN
- STL
2 stops10h 58m
United Airlines
Mon 5/256:00 am
STL
- SAN
1 stop7h 21m
United Airlines
Deal found 5/8![United Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:15 am
SAN
- SGF
1 stop9h 58m
Delta
Sat 8/156:06 am
SGF
- SAN
1 stop7h 01m
Delta
Deal found 5/8![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:40 am
SAN
- STL
1 stop9h 33m
United Airlines
Sat 5/306:00 am
STL
- SAN
2 stops16h 53m
United Airlines
Deal found 5/11![United Airlines logo]()
$443
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:40 pm
SAN
- STL
1 stop7h 50m
Southwest
Tue 6/238:30 am
STL
- SAN
Nonstop3h 40m
Southwest
Deal found 5/12![Southwest logo]()
$406
Last-minute flights from San Diego to MissouriDiscover last-minute flight deals from San Diego to Missouri. Data last updated May 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Missouri. Data last updated May 13, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:37 am
SAN
- STL
1 stop7h 46m
Frontier
Sat 6/68:08 pm
STL
- SAN
1 stop5h 42m
Frontier
Deal found 5/10![Frontier logo]()
$249
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:37 am
SAN
- STL
1 stop7h 46m
Frontier
Mon 6/19:21 pm
STL
- SAN
1 stop13h 26m
Frontier
Deal found 5/9![Frontier logo]()
$254
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:36 pm
SAN
- STL
1 stop20h 30m
Frontier
Wed 6/107:03 pm
STL
- SAN
1 stop15h 45m
Frontier
Deal found 5/9![Frontier logo]()
$224
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sat 6/68:08 pm
STL
- SAN
1 stop5h 42m
Frontier
Deal found 5/10![Frontier logo]()
$192
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- MCI
1 stop5h 24m
Frontier
Sat 6/62:34 pm
MCI
- SAN
1 stop11h 16m
Frontier
Deal found 5/10![Frontier logo]()
$230
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- STL
1 stop10h 58m
Frontier
Wed 6/38:08 pm
STL
- SAN
1 stop5h 42m
Frontier
Deal found 5/10![Frontier logo]()
$230
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:43 am
SAN
- STL
1 stop8h 28m
Frontier
Mon 6/157:38 pm
STL
- SAN
1 stop6h 15m
Frontier
Deal found 5/9![Frontier logo]()
$240
This Expedia deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:25 am
SAN
- STL
1 stop10h 58m
Frontier
Tue 6/167:46 pm
STL
- SAN
1 stop15h 02m
Frontier
Deal found 5/10![Frontier logo]()
$210
This Booking.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:28 pm
SAN
- MCI
1 stop21h 32m
Frontier
Mon 6/151:45 pm
MCI
- SAN
1 stop12h 08m
Frontier
Deal found 5/9![Frontier logo]()
$243
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:04 am
SAN
- STL
1 stop6h 49m
Frontier
Mon 6/157:38 pm
STL
- SAN
1 stop6h 15m
Frontier
Deal found 5/9![Frontier logo]()
$247
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:43 am
SAN
- STL
1 stop7h 08m
Frontier
Wed 6/248:08 pm
STL
- SAN
1 stop15h 01m
Frontier
Deal found 5/10![Frontier logo]()
$211
This Expedia deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:25 am
SAN
- STL
1 stop10h 28m
Frontier
Mon 6/297:38 pm
STL
- SAN
1 stop6h 15m
Frontier
Deal found 5/12![Frontier logo]()
$250
One-way flights from San Diego to MissouriSearch for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
Search for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
SAN
- MCI
1 stop29h 24m
Frontier
Deal found 5/9![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 5/9![Frontier logo]()
$81
This Frontier deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- MCI
1 stop5h 24m
Frontier
Deal found 5/11![Frontier logo]()
$105
This Priceline deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:04 am
SAN
- STL
1 stop7h 19m
Frontier
Deal found 5/12![Frontier logo]()
$105
This Mytrip deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:43 am
SAN
- STL
1 stop7h 08m
Frontier
Deal found 5/9![Frontier logo]()
$106
This Super.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:53 pm
SAN
- STL
1 stop18h 12m
Frontier
Deal found 5/11![Frontier logo]()
$110
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 5/12![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:25 am
SAN
- MCI
1 stop29h 24m
Frontier
Deal found 5/10![Frontier logo]()
$112
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:53 pm
SAN
- MCI
1 stop13h 02m
Frontier
Deal found 5/11![Frontier logo]()
$116
This Super.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:43 am
SAN
- STL
1 stop8h 28m
Frontier
Deal found 5/9![Frontier logo]()
$118
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:43 am
SAN
- STL
1 stop8h 28m
Frontier
Deal found 5/12![Frontier logo]()
$119
This Super.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 5/12![Frontier logo]()
$120
Find flight deals from San Diego to Missouri
Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated May 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $192 (Trip.com) |
One-way from | $81 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $373 |
Good round-trip deal | $361 or less |
Good one-way deal | $233 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Thu 6/25
6:55 pm-1:30 am
1 stop4h 35m
Kansas City
Mon 6/29
6:30 pm-9:05 pm
1 stop4h 35m
$272
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Sat 7/11
10:54 am-7:12 pm
1 stop6h 18m
Kansas City
Mon 7/13
5:42 pm-11:30 pm
1 stop7h 48m
$277
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Mon 7/20
9:30 pm-9:24 am
1 stop9h 54m
Kansas City
Sat 7/25
4:04 pm-8:15 pm
1 stop6h 11m
$277
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Thu 6/11
11:55 am-7:45 pm
1 stop5h 50m
Kansas City
Mon 6/15
5:50 am-10:35 am
1 stop6h 45m
$277
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Fri 6/5
10:15 pm-9:46 am
1 stop9h 31m
Kansas City
Thu 6/11
3:55 pm-7:16 pm
1 stop5h 21m
$277
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Sun 8/30
6:15 am-4:58 pm
1 stop8h 43m
Kansas City
Mon 9/7
7:40 pm-11:42 pm
1 stop6h 02m
$277
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Wed 5/27
7:00 am-4:57 pm
1 stop7h 57m
Kansas City
Sat 5/30
5:52 pm-12:07 am
1 stop8h 15m
$284
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 7/24
5:01 pm-12:41 am
1 stop5h 40m
Lambert-St Louis
Wed 7/29
7:55 pm-11:50 pm
1 stop5h 55m
$297
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Fri 6/5
10:15 pm-9:46 am
1 stop9h 31m
Kansas City
Sun 6/7
3:55 pm-7:16 pm
1 stop5h 21m
$298
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Sat 8/1
10:40 pm-7:45 am
1 stop7h 05m
Lambert-St Louis
Mon 8/3
4:45 pm-9:05 pm
2 stops6h 20m
$323
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
SAN-STL
SAN-MCI
SAN-COU
SAN-TBN
SAN-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Missouri
SAN-USMO
SAN-STL
SAN-MCI
SAN-COU
SAN-TBN
How far ahead should I book a flight from San Diego to Missouri?
To ensure you get the cheapest price possible for a flight from San Diego to Missouri, you should look to book at least 86 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from San Diego to Missouri?
Currently, October is the cheapest month in which you can book a flight from San Diego to Missouri (average of $74). Flying from San Diego to Missouri in January is currently the most expensive (average of $214). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to MO?
Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 13, 2026.
One of the essential ways to save on airfare from San Diego to Missouri is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 39% on airfare.
How much does it cost to fly round-trip from San Diego to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 13, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Missouri by cabin class
Find flights from San Diego to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Missouri flights
Browse other San Diego and Missouri flight options. Last updated on May 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Missouri flights
Consider these flights traveling from San Diego to Missouri.
Top 8 airlines flying from San Diego to Missouri
Discover the top 8 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$96 | Average$229 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$104 | Average$218 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$133 | Average$322 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$386 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$217 | Average$403 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$232 | Average$397 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$236 | Average$355 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$267 | Average$459 | FlexibilityNo cancel fee | On-time63% |