$78+ Cheap flights from San Diego (SAN) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Sep 19 — Sep 261
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to MissouriExplore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2026.
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:25 am -
1 stop10h 52m
Sat 10/107:42 pm -
1 stop6h 14m
Deal found 8/19![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:25 am -
1 stop10h 52m
Mon 10/58:10 pm -
1 stop21h 49m
Deal found 8/18![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:25 am -
1 stop6h 59m
Sat 10/177:42 pm -
1 stop6h 14m
Deal found 8/15![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:54 pm -
1 stop24h 54m
Mon 10/128:43 pm -
1 stop29h 13m
Deal found 8/19![Frontier logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:25 am -
1 stop10h 52m
Mon 9/218:10 pm -
1 stop21h 49m
Deal found 8/15![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:25 am -
1 stop11h 12m
Tue 9/228:32 pm -
1 stop29h 19m
Deal found 8/18![Frontier logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:25 am -
1 stop10h 52m
Sat 9/268:10 pm -
1 stop21h 49m
Deal found 8/18![Frontier logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:25 am -
1 stop10h 52m
Tue 10/612:17 pm -
2 stops13h 34m
Deal found 8/18![Frontier logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:32 pm -
1 stop14h 50m
Mon 11/22:17 pm -
1 stop27h 24m
Deal found 8/15![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:54 pm -
1 stop24h 23m
Tue 9/2212:17 pm -
2 stops37h 34m
Deal found 8/18![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:25 am -
1 stop10h 52m
Sat 9/1912:17 pm -
1 stop6h 42m
Deal found 8/15![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:25 am -
1 stop11h 12m
Wed 9/238:32 pm -
1 stop29h 19m
Deal found 8/19![Frontier logo]()
$215
Best flights from San Diego to MissouriDiscover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 20, 2026.
Discover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 20, 2026.
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:07 pm -
1 stop5h 33m
Sat 9/121:36 pm -
1 stop5h 34m
Deal found 8/15![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:40 pm -
1 stop4h 55m
Sat 10/173:35 pm -
Nonstop3h 30m
Deal found 8/17![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:45 am -
2 stops11h 24m
Sat 10/3111:20 am -
2 stops13h 31m
Deal found 8/19![Delta logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:45 pm -
1 stop15h 25m
Mon 9/144:20 pm -
2 stops33h 31m
Deal found 8/15![Multiple Airlines logo]()
$371
This Alaska Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:12 pm -
1 stop20h 58m
Wed 10/217:02 am -
2 stops13h 41m
Deal found 8/18![Alaska Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:15 pm -
1 stop6h 44m
Sun 10/255:10 am -
1 stop6h 00m
Deal found 8/15![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 pm -
Nonstop3h 15m
Mon 9/287:20 am -
Nonstop3h 15m
Deal found 8/19![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:11 pm -
1 stop5h 31m
Wed 10/215:06 pm -
1 stop7h 21m
Deal found 8/19![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:37 am -
1 stop9h 44m
Wed 9/94:00 pm -
1 stop7h 19m
Deal found 8/19![Delta logo]()
$374
This Alaska Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:10 pm -
1 stop9h 49m
Mon 10/197:02 am -
1 stop9h 36m
Deal found 8/15![Alaska Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:55 am -
Nonstop3h 30m
Fri 11/278:25 am -
1 stop6h 15m
Deal found 8/19![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:00 am -
1 stop6h 11m
Sat 10/31:37 pm -
1 stop5h 28m
Deal found 8/15![United Airlines logo]()
$339
This Alaska Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:30 am -
1 stop8h 34m
Sun 11/18:29 am -
2 stops13h 58m
Deal found 8/19![Alaska Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 pm -
Nonstop3h 15m
Thu 9/247:20 am -
Nonstop3h 15m
Deal found 8/18![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:20 pm -
1 stop4h 40m
Tue 11/248:00 pm -
1 stop5h 20m
Deal found 8/19![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:13 am -
1 stop6h 42m
Wed 9/95:30 am -
2 stops8h 05m
Deal found 8/19![United Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:59 pm -
2 stops13h 11m
Fri 9/44:20 pm -
1 stop25h 21m
Deal found 8/16![Multiple Airlines logo]()
$544
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:05 am -
2 stops6h 55m
Mon 2/810:20 am -
1 stop5h 00m
Deal found 8/15![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:20 am -
2 stops9h 35m
Sat 9/53:12 pm -
1 stop8h 56m
Deal found 8/17![United Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:36 pm -
1 stop16h 49m
Mon 9/712:10 pm -
2 stops37h 41m
Deal found 8/19![Multiple Airlines logo]()
$545
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:55 am -
Nonstop3h 30m
Mon 11/234:50 pm -
1 stop7h 25m
Deal found 8/16![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:20 am -
2 stops12h 26m
Thu 9/312:59 pm -
1 stop7h 31m
Deal found 8/17![United Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:25 am -
2 stops27h 25m
Mon 9/74:20 pm -
1 stop25h 21m
Deal found 8/19![Multiple Airlines logo]()
$562
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:40 pm -
Nonstop3h 30m
Sun 11/86:10 am -
1 stop5h 50m
Deal found 8/17![Southwest logo]()
$408
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:45 am -
1 stop5h 39m
Sat 9/51:37 pm -
2 stops9h 08m
Deal found 8/16![United Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:36 pm -
1 stop16h 49m
Sun 9/65:10 pm -
2 stops17h 55m
Deal found 8/18![Multiple Airlines logo]()
$569
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:37 pm -
1 stop6h 02m
Tue 9/2211:20 am -
1 stop9h 10m
Deal found 8/15![United Airlines logo]()
$418
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:25 pm -
1 stop5h 40m
Mon 10/1210:15 am -
Nonstop3h 30m
Deal found 8/18![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:20 am -
2 stops10h 26m
Sat 9/58:30 am -
2 stops10h 56m
Deal found 8/17![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:24 pm -
2 stops7h 06m
Mon 9/146:00 am -
2 stops7h 35m
Deal found 8/18![United Airlines logo]()
$422
Last-minute flights from San Diego to MissouriDiscover last-minute flight deals from San Diego to Missouri. Data last updated August 20, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Missouri. Data last updated August 20, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:45 pm -
1 stop25h 28m
Wed 9/98:10 pm -
1 stop5h 41m
Deal found 8/18![Frontier logo]()
$209
This CheapOair deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:45 pm -
1 stop25h 28m
Tue 9/86:45 pm -
1 stop24h 14m
Deal found 8/16![Frontier logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:54 pm -
1 stop24h 43m
Fri 9/188:32 pm -
1 stop29h 19m
Deal found 8/19![Frontier logo]()
$226
This Frontier deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:25 am -
1 stop11h 12m
Wed 9/168:32 pm -
1 stop5h 19m
Deal found 8/17![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:25 am -
1 stop11h 12m
Tue 9/228:32 pm -
1 stop29h 19m
Deal found 8/18![Frontier logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:54 pm -
1 stop24h 23m
Tue 9/2212:17 pm -
2 stops37h 34m
Deal found 8/18![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:25 am -
1 stop10h 52m
Sat 9/1912:17 pm -
1 stop6h 42m
Deal found 8/15![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:25 am -
1 stop11h 12m
Wed 9/238:32 pm -
1 stop29h 19m
Deal found 8/19![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:03 pm -
1 stop12h 29m
Mon 9/218:10 pm -
1 stop21h 49m
Deal found 8/15![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:25 am -
1 stop10h 52m
Mon 9/218:10 pm -
1 stop21h 49m
Deal found 8/15![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:25 am -
1 stop10h 52m
Tue 9/2212:17 pm -
2 stops26h 36m
Deal found 8/15![Frontier logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:25 am -
1 stop10h 52m
Sat 9/268:10 pm -
1 stop21h 49m
Deal found 8/18![Frontier logo]()
$198
One-way flights from San Diego to MissouriSearch for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated August 20, 2026.
Search for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated August 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:25 am -
1 stop10h 52m
Deal found 8/19![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:25 am -
1 stop10h 52m
Deal found 8/19![Frontier logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:54 pm -
1 stop24h 23m
Deal found 8/18![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:25 am -
1 stop10h 52m
Deal found 8/18![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:25 am -
1 stop10h 52m
Deal found 8/19![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:53 pm -
1 stop20h 31m
Deal found 8/19![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:25 am -
1 stop6h 59m
Deal found 8/19![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:25 am -
1 stop11h 23m
Deal found 8/15![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:32 pm -
1 stop14h 50m
Deal found 8/16![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:25 am -
1 stop6h 59m
Deal found 8/17![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:03 pm -
1 stop12h 29m
Deal found 8/15![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:53 pm -
1 stop24h 55m
Deal found 8/15![Frontier logo]()
$98
Find flight deals from San Diego to Missouri
Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated August 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (Kiwi.com) |
One-way from | $78 (Kiwi.com) |
Popular in | April |
Cheapest in | November |
Average price | $312 |
Good round-trip deal | $362 or less |
Good one-way deal | $233 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 20, 2026.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSt. Louis
SAN San Diego - STL Lambert-St Louis
SANSTL
San Diego
Sat 9/5
4:07 pm-11:40 pm
1 stop5h 33m
Lambert-St Louis
Sat 9/12
1:36 pm-5:10 pm
1 stop5h 34m
$307
San DiegoSt. Louis
SAN San Diego - STL Lambert-St Louis
SANSTL
San Diego
Wed 9/23
2:15 pm-10:59 pm
1 stop6h 44m
Lambert-St Louis
Sun 10/25
5:10 am-9:10 am
1 stop6h 00m
$307
San DiegoKansas City
SAN San Diego - MCI Kansas City
SANMCI
San Diego
Wed 10/14
4:40 pm-11:35 pm
1 stop4h 55m
Kansas City
Sat 10/17
3:35 pm-5:05 pm
Nonstop3h 30m
$322
Quickest round-trip
San DiegoKansas City
SAN San Diego - MCI Kansas City
SANMCI
San Diego
Thu 9/24
7:00 pm-12:15 am
Nonstop3h 15m
Kansas City
Mon 9/28
7:20 am-8:35 am
Nonstop3h 15m
$322
San DiegoSpringfield
SAN San Diego - SGF Springfield-Branson
SANSGF
San Diego
Sat 10/3
4:11 pm-11:42 pm
1 stop5h 31m
Springfield-Branson
Wed 10/21
5:06 pm-10:27 pm
1 stop7h 21m
$339
San DiegoSpringfield
SAN San Diego - SGF Springfield-Branson
SANSGF
San Diego
Sat 9/12
8:00 am-4:11 pm
1 stop6h 11m
Springfield-Branson
Sat 10/3
1:37 pm-5:05 pm
1 stop5h 28m
$339
San DiegoSt. Louis
SAN San Diego - STL Lambert-St Louis
SANSTL
San Diego
Sat 10/24
7:45 am-9:09 pm
2 stops11h 24m
Lambert-St Louis
Sat 10/31
11:20 am-10:51 pm
2 stops13h 31m
$353
San DiegoFort Leonard Wood
SAN San Diego - TBN Fort Leonard Wood Waynesville Regional
SANTBN
San Diego
Fri 9/11
6:45 pm-12:10 pm
1 stop15h 25m
Fort Leonard Wood Waynesville Regional
Mon 9/14
4:20 pm-11:51 pm
2 stops33h 31m
$371
San DiegoSt. Louis
SAN San Diego - STL Lambert-St Louis
SANSTL
San Diego
Thu 11/19
11:55 am-5:25 pm
Nonstop3h 30m
Lambert-St Louis
Fri 11/27
8:25 am-12:40 pm
1 stop6h 15m
$372
San DiegoSpringfield
SAN San Diego - SGF Springfield-Branson
SANSGF
San Diego
Fri 9/4
10:37 am-10:21 pm
1 stop9h 44m
Springfield-Branson
Wed 9/9
4:00 pm-9:19 pm
1 stop7h 19m
$374
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
SAN-STL
SAN-MCI
SAN-TBN
SAN-SGF
SAN-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Missouri
SAN-USMO
SAN-STL
SAN-MCI
SAN-TBN
SAN-SGF
What is the cheapest month to book a flight from San Diego to Missouri?
Currently, August is the cheapest month in which you can book a flight from San Diego to Missouri (average of $342). Flying from San Diego to Missouri in March is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to MO?
Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2026.
One of the essential ways to save on airfare from San Diego to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.
How much does it cost to fly round-trip from San Diego to Missouri?
Airfare is below average for this route at the moment.
San Diego to Missouri flights typically cost between $261 and $482 in October.The cheapest round-trip price found within the last 5 days was $151 on Frontier (Oct 3-Oct 10).
How far ahead should I book a flight from San Diego to Missouri?
To ensure you get the cheapest price possible for a flight from San Diego to Missouri, you should look to book at least 83 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 20, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for San Diego to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Missouri by cabin class
Find flights from San Diego to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Missouri flights
Browse other San Diego and Missouri flight options. Last updated on August 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Missouri flights
Consider these flights traveling from San Diego to Missouri.
Top 7 airlines flying from San Diego to Missouri
Discover the top 7 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$91 | Average$443 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$104 | Average$255 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$198 | Average$330 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$386 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$236 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$416 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$452 | FlexibilityNo cancel fee | On-time63% |