How popular is this Myrtle Beach to St. Louis flight route?

Flights from Myrtle Beach Intl to Lambert-St Louis have been viewed 1 times in the past calendar month.

What are the cheapest airlines flying from Myrtle Beach to St. Louis round-trip?

Cheapflights users have booked flights from Myrtle Beach to St. Louis round-trip from $179. Other airlines that can offer you cheap pricing are American Airlines, from $261, and Southwest, from $325. You may be able to fly from Myrtle Beach to St. Louis for 51% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Myrtle Beach to St. Louis one-way?

For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $85. Users have also found prices from $89 and $94 on Southwest and American Airlines, respectively.

What is the cheapest day to fly from Myrtle Beach to St. Louis?

Travelers seeking maximum savings on their Myrtle Beach to St. Louis flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the cheapest flights from Myrtle Beach to St. Louis?

On average you can expect to pay $407 for a flight from Myrtle Beach to St. Louis. The cheapest flight overall is $311 while the most popular route, (Myrtle Beach Intl - Lambert-St Louis) is currently priced at $179.

What are the most popular airlines that fly from Myrtle Beach to St. Louis?

The most popular airlines flying from Myrtle Beach to St. Louis are American Airlines, Delta and Southwest. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Myrtle Beach to St. Louis?

Saturday flights are found to be more expensive to fly from Myrtle Beach to St. Louis. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

What is the cheapest month to fly from Myrtle Beach to St. Louis?

The best pricing can be found in the month of June. Prices to St. Louis from Myrtle Beach average $372. You can even find prices in June for less than $372, as users have found deals to St. Louis from as low as $128. The month of February appears to be one of the more expensive times to travel to St. Louis from Myrtle Beach. Flying in the targeted month can save you up to 13%.

Can I find deals for flights from Myrtle Beach to St. Louis that include hotel bookings?

Yes. In addition to deals on Myrtle Beach to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Myrtle Beach to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to St. Louis.

Can I find deals for business class flights from Myrtle Beach to St. Louis?

Yes. Cheapflights offers flight deals from Myrtle Beach to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$85+ Flights from Myrtle Beach to St. Louis

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Cheap flight deals from Myrtle Beach to St. Louis

Round-trip from	$179 (FlightHub)
One-way from	$85 (Mytrip)
Popular in	February
Cheapest in	June
Average price	$323
Good round-trip deal	$316 or less

From Myrtle Beach Intl to Lambert-St Louis

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One-way flight from Myrtle Beach Intl to Lambert-St Louis

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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Price to beat on a round-trip flight from Myrtle Beach Intl to Lambert-St Louis.

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Find flight deals from Myrtle Beach to St. Louis

Cheapest flights from Myrtle Beach to St. Louis
Explore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Thu 8/218:48 pmMYR - STL

1 stop17h 44mSpirit Airlines

Sun 8/242:30 pmSTL - MYR

1 stop4h 23mSpirit Airlines

Deal found 6/29

$179

Mon 7/147:56 pmMYR - STL

2 stops21h 35mMultiple Airlines

Fri 7/1810:47 amSTL - MYR

1 stop10h 51mMultiple Airlines

Deal found 6/28

$248

Tue 8/1210:53 amMYR - STL

1 stop6h 21mAmerican Airlines

Sat 8/167:19 amSTL - MYR

1 stop8h 03mAmerican Airlines

Deal found 6/28

$261

Sat 10/111:50 pmMYR - STL

Nonstop2h 10mSouthwest

Sat 10/1810:35 amSTL - MYR

Nonstop1h 50mSouthwest

Deal found 6/28

$325

Thu 10/165:25 pmMYR - STL

2 stops18h 24mUnited Airlines

Tue 10/218:05 amSTL - MYR

1 stop7h 39mUnited Airlines

Deal found 6/28

$431

Mon 7/147:50 pmMYR - STL

1 stop5h 03mDelta

Fri 7/189:27 amSTL - MYR

1 stop4h 45mDelta

Deal found 6/28

$437

Best flights from Myrtle Beach to St. Louis
Discover carefully curated flight deals from Myrtle Beach to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 30, 2025.

Thu 8/218:48 pmMYR - STL

1 stop17h 44mSpirit Airlines

Sun 8/242:30 pmSTL - MYR

1 stop4h 23mSpirit Airlines

Deal found 6/29

$179

Mon 7/147:56 pmMYR - STL

2 stops21h 35mMultiple Airlines

Fri 7/1810:47 amSTL - MYR

1 stop10h 51mMultiple Airlines

Deal found 6/28

$248

Tue 8/1210:53 amMYR - STL

1 stop6h 21mAmerican Airlines

Sat 8/167:19 amSTL - MYR

1 stop8h 03mAmerican Airlines

Deal found 6/28

$261

Sat 10/111:50 pmMYR - STL

Nonstop2h 10mSouthwest

Sat 10/1810:35 amSTL - MYR

Nonstop1h 50mSouthwest

Deal found 6/28

$325

Thu 10/165:25 pmMYR - STL

2 stops18h 24mUnited Airlines

Tue 10/218:05 amSTL - MYR

1 stop7h 39mUnited Airlines

Deal found 6/28

$431

Mon 7/147:50 pmMYR - STL

1 stop5h 03mDelta

Fri 7/189:27 amSTL - MYR

1 stop4h 45mDelta

Deal found 6/28

$437

Last-minute flights from Myrtle Beach to St. Louis
Discover last-minute flight deals from Myrtle Beach to St. Louis. Data last updated June 30, 2025 and is based on user searches.

Thu 7/37:40 pmMYR - STL

1 stop5h 19mAmerican Airlines

Sat 7/510:08 amSTL - MYR

1 stop7h 19mAmerican Airlines

Deal found 6/28

$452

Mon 7/147:56 pmMYR - STL

2 stops21h 35mMultiple Airlines

Fri 7/1810:47 amSTL - MYR

1 stop10h 51mMultiple Airlines

Deal found 6/28

$248

Mon 7/141:17 pmMYR - STL

3 stops28h 14mSpirit Airlines

Fri 7/1810:47 amSTL - MYR

1 stop10h 51mSpirit Airlines

Deal found 6/28

$273

Mon 7/147:50 pmMYR - STL

1 stop5h 03mDelta

Fri 7/189:27 amSTL - MYR

1 stop4h 45mDelta

Deal found 6/28

$437

Tue 7/1510:54 amMYR - STL

2 stops12h 51mUnited Airlines

Sat 7/196:33 amSTL - MYR

1 stop7h 02mUnited Airlines

Deal found 6/30

$773

One-way flights from Myrtle Beach to St. Louis
Search for one-way flight options from Myrtle Beach to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 30, 2025.

Wed 7/238:58 pmMYR - STL

1 stop13h 54mSpirit Airlines

Deal found 6/28

$85

Thu 7/317:10 pmMYR - STL

1 stop5h 55mSouthwest

Deal found 6/28

$89

Tue 8/57:50 pmMYR - STL

1 stop5h 09mAmerican Airlines

Deal found 6/28

$94

Sun 8/37:50 pmMYR - STL

1 stop5h 03mDelta

Deal found 6/28

$99

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 8/21

8:48 pm-1:32 pm

1 stop17h 44m

Lambert-St Louis

Sun 8/24

2:30 pm-7:53 pm

1 stop4h 23m

$179

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Mon 7/14

7:56 pm-4:31 pm

2 stops21h 35m

Lambert-St Louis

Fri 7/18

10:47 am-10:38 pm

1 stop10h 51m

$248

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 8/12

10:53 am-4:14 pm

1 stop6h 21m

Lambert-St Louis

Sat 8/16

7:19 am-4:22 pm

1 stop8h 03m

$261

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 10/11

1:50 pm-3:00 pm

Nonstop2h 10m

Lambert-St Louis

Sat 10/18

10:35 am-1:25 pm

Nonstop1h 50m

$325

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 10/16

5:25 pm-10:49 am

2 stops18h 24m

Lambert-St Louis

Tue 10/21

8:05 am-4:44 pm

1 stop7h 39m

$431

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Mon 7/14

7:50 pm-11:53 pm

1 stop5h 03m

Lambert-St Louis

Fri 7/18

9:27 am-3:12 pm

1 stop4h 45m

$437

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Wed 7/23

8:58 pm-9:52 am

1 stop13h 54m

$85

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 7/31

7:10 pm-12:05 am

1 stop5h 55m

$89

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 8/5

7:50 pm-11:59 pm

1 stop5h 09m

$94

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sun 8/3

7:50 pm-11:53 pm

1 stop5h 03m

$99

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Best time to book a flight from Myrtle Beach to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Myrtle Beach with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to St. Louis

What is the cheapest month to book a flight from Myrtle Beach to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to St. Louis (average of $311). Flying from Myrtle Beach to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to STL?

One of the essential ways to save on airfare from Myrtle Beach to St. Louis is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 33% on airfare.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Myrtle Beach to St. Louis, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,278 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,969 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,852 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Spirit Airlines

6.3

Okay

8,096 reviews

Southwest

8.0

Very good

4,278 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

How popular is this Myrtle Beach to St. Louis flight route?
Flights from Myrtle Beach Intl to Lambert-St Louis have been viewed 1 times in the past calendar month.
What are the cheapest airlines flying from Myrtle Beach to St. Louis round-trip?
Cheapflights users have booked flights from Myrtle Beach to St. Louis round-trip from $179. Other airlines that can offer you cheap pricing are American Airlines, from $261, and Southwest, from $325. You may be able to fly from Myrtle Beach to St. Louis for 51% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Myrtle Beach to St. Louis one-way?
For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $85. Users have also found prices from $89 and $94 on Southwest and American Airlines, respectively.
What are the cheapest flights from Myrtle Beach to St. Louis?
On average you can expect to pay $407 for a flight from Myrtle Beach to St. Louis. The cheapest flight overall is $311 while the most popular route, (Myrtle Beach Intl - Lambert-St Louis) is currently priced at $179.
Can I find deals for flights from Myrtle Beach to St. Louis that include hotel bookings?
Yes. In addition to deals on Myrtle Beach to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Myrtle Beach to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to St. Louis.
Can I find deals for business class flights from Myrtle Beach to St. Louis?
Yes. Cheapflights offers flight deals from Myrtle Beach to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Myrtle Beach to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to St. Louis (average of $311). Flying from Myrtle Beach to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

O'Fallon

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Fairview Heights

Collinsville

Eureka

St. Peters

Glencoe

Alton

Festus

Chesterfield

Farmington

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Top 3 airlines flying from Myrtle Beach to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$196	Average$377	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$264	Average$396	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$292	Average$382	FlexibilityNo cancel fee	On-time63%

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$85+ Cheap flights from Myrtle Beach to St. Louis (MYR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Myrtle Beach to St. Louis with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Myrtle Beach to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Find flight deals from Myrtle Beach to St. Louis

Cheapest flights from Myrtle Beach to St. LouisExplore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Explore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.

Best time to book a flight from Myrtle Beach to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Myrtle Beach with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to St. Louis

What is the cheapest month to book a flight from Myrtle Beach to St. Louis?

What is the cheapest time of day to fly from MYR to STL?

Find hourly flight availability from Myrtle Beach to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Myrtle Beach to St. Louis, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Myrtle Beach to St. Louis flight route?

What are the cheapest airlines flying from Myrtle Beach to St. Louis round-trip?

What are the cheapest airlines to fly from Myrtle Beach to St. Louis one-way?

What are the cheapest flights from Myrtle Beach to St. Louis?

Can I find deals for flights from Myrtle Beach to St. Louis that include hotel bookings?

How can I find direct flights from Myrtle Beach to St. Louis?

Can I find deals for business class flights from Myrtle Beach to St. Louis?

What is the cheapest month to book a flight from Myrtle Beach to St. Louis?

Traveling to a place near Myrtle Beach?

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Alternative routes for Myrtle Beach to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Myrtle Beach to St. Louis

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Cheapest flights from Myrtle Beach to St. Louis
Explore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.