$124+ Cheap flights from Myrtle Beach to St. Louis (MYR - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Oct 3 — Oct 101
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to St. Louis
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Last-minute
One-way
Cheapest flights from Myrtle Beach to St. LouisExplore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
Explore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:35 pm -
1 stop28h 19m
Mon 10/52:29 pm -
2 stops18h 36m
Deal found 9/2![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:41 pm -
1 stop9h 32m
Thu 10/294:26 pm -
1 stop15h 19m
Deal found 8/30![Multiple Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop3h 59m
Mon 10/511:17 am -
1 stop7h 13m
Deal found 9/2![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:40 pm -
2 stops10h 05m
Thu 11/121:20 pm -
1 stop5h 40m
Deal found 9/1![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:00 am -
2 stops7h 55m
Mon 10/52:00 pm -
2 stops6h 45m
Deal found 9/2![Southwest logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:46 pm -
1 stop26h 48m
Mon 9/212:29 pm -
2 stops23h 48m
Deal found 8/30![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:41 pm -
1 stop9h 32m
Mon 10/266:35 pm -
2 stops37h 33m
Deal found 8/31![Multiple Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 34m
Sat 10/33:54 pm -
1 stop4h 47m
Deal found 8/30![Delta logo]()
$411
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:40 am -
1 stop6h 35m
Thu 10/295:10 am -
2 stops9h 10m
Deal found 8/30![Southwest logo]()
$416
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 pm -
1 stop4h 30m
Thu 9/248:00 am -
1 stop10h 25m
Deal found 9/2![Southwest logo]()
$418
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:55 pm -
2 stops7h 55m
Mon 10/262:00 pm -
2 stops6h 50m
Deal found 8/31![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:40 am -
2 stops9h 20m
Sat 10/176:05 am -
1 stop3h 55m
Deal found 8/31![Southwest logo]()
$423
Best flights from Myrtle Beach to St. LouisDiscover carefully curated flight deals from Myrtle Beach to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
Discover carefully curated flight deals from Myrtle Beach to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:51 pm -
1 stop6h 05m
Thu 11/127:05 am -
1 stop5h 28m
Deal found 9/1![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:00 am -
2 stops7h 55m
Mon 10/52:00 pm -
2 stops6h 45m
Deal found 9/2![Southwest logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:08 am -
1 stop6h 57m
Tue 9/226:53 am -
1 stop3h 27m
Deal found 9/2![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:15 am -
1 stop5h 15m
Mon 10/262:30 pm -
1 stop6h 20m
Deal found 8/31![Southwest logo]()
$411
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 34m
Sat 10/33:54 pm -
1 stop4h 47m
Deal found 8/30![Delta logo]()
$411
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:40 am -
1 stop6h 35m
Thu 10/295:10 am -
2 stops9h 10m
Deal found 8/30![Southwest logo]()
$416
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:56 pm -
1 stop5h 11m
Sun 10/46:00 am -
1 stop6h 33m
Deal found 8/31![Delta logo]()
$429
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 pm -
1 stop4h 30m
Thu 9/248:00 am -
1 stop10h 25m
Deal found 9/2![Southwest logo]()
$418
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:25 am -
2 stops8h 50m
Sun 10/47:00 am -
2 stops7h 25m
Deal found 8/30![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:40 am -
1 stop5h 55m
Thu 9/1711:40 am -
1 stop7h 05m
Deal found 8/29![Southwest logo]()
$459
Last-minute flights from Myrtle Beach to St. LouisDiscover last-minute flight deals from Myrtle Beach to St. Louis. Data last updated September 3, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to St. Louis. Data last updated September 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:46 pm -
1 stop26h 48m
Mon 9/212:29 pm -
2 stops23h 48m
Deal found 8/30![Multiple Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 pm -
1 stop4h 30m
Thu 9/248:00 am -
1 stop10h 25m
Deal found 9/2![Southwest logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:35 pm -
1 stop28h 19m
Mon 10/52:29 pm -
2 stops18h 36m
Deal found 9/2![Multiple Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop3h 59m
Mon 10/511:17 am -
1 stop7h 13m
Deal found 9/2![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:00 am -
2 stops7h 55m
Mon 10/52:00 pm -
2 stops6h 45m
Deal found 9/2![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 34m
Sat 10/33:54 pm -
1 stop4h 47m
Deal found 8/30![Delta logo]()
$411
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:40 am -
2 stops9h 20m
Sat 10/176:05 am -
1 stop3h 55m
Deal found 8/31![Southwest logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:41 pm -
1 stop9h 32m
Mon 10/266:35 pm -
2 stops37h 33m
Deal found 8/31![Multiple Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:55 pm -
2 stops7h 55m
Mon 10/262:00 pm -
2 stops6h 50m
Deal found 8/31![Southwest logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:41 pm -
1 stop9h 32m
Thu 10/294:26 pm -
1 stop15h 19m
Deal found 8/30![Multiple Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:40 am -
1 stop6h 35m
Thu 10/295:10 am -
2 stops9h 10m
Deal found 8/30![Southwest logo]()
$416
One-way flights from Myrtle Beach to St. LouisSearch for one-way flight options from Myrtle Beach to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 3, 2026.
Search for one-way flight options from Myrtle Beach to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:50 am -
2 stops27h 20m
Deal found 8/31![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:58 pm -
2 stops26h 42m
Deal found 8/31![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:03 pm -
2 stops26h 37m
Deal found 8/31![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:36 am -
2 stops33h 04m
Deal found 9/2![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:59 am -
3 stops26h 11m
Deal found 9/1![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:58 pm -
2 stops16h 11m
Deal found 9/2![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:36 am -
2 stops33h 04m
Deal found 8/29![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:25 pm -
2 stops24h 15m
Deal found 9/2![Multiple Airlines logo]()
$148
Find flight deals from Myrtle Beach to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $345 (Kiwi.com) |
One-way from | $124 (Kiwi.com) |
Popular in | July |
Cheapest in | October |
Average price | $391 |
Good round-trip deal | $315 or less |
Good one-way deal | $229 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 3, 2026.
Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Mon 11/9
6:51 pm-11:56 pm
1 stop6h 05m
Lambert-St Louis
Thu 11/12
7:05 am-1:33 pm
1 stop5h 28m
$367
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Wed 9/30
11:00 am-5:55 pm
2 stops7h 55m
Lambert-St Louis
Mon 10/5
2:00 pm-9:45 pm
2 stops6h 45m
$377
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Fri 10/23
6:15 am-10:30 am
1 stop5h 15m
Lambert-St Louis
Mon 10/26
2:30 pm-9:50 pm
1 stop6h 20m
$411
Quickest round-trip
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Sat 10/3
6:00 am-9:34 am
1 stop4h 34m
Lambert-St Louis
Sat 10/3
3:54 pm-9:41 pm
1 stop4h 47m
$411
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Mon 10/26
6:40 am-12:15 pm
1 stop6h 35m
Lambert-St Louis
Thu 10/29
5:10 am-3:20 pm
2 stops9h 10m
$416
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Thu 9/17
6:15 pm-9:45 pm
1 stop4h 30m
Lambert-St Louis
Thu 9/24
8:00 am-7:25 pm
1 stop10h 25m
$418
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Sat 10/3
3:56 pm-8:07 pm
1 stop5h 11m
Lambert-St Louis
Sun 10/4
6:00 am-1:33 pm
1 stop6h 33m
$429
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Sat 10/3
8:25 am-4:15 pm
2 stops8h 50m
Lambert-St Louis
Sun 10/4
7:00 am-3:25 pm
2 stops7h 25m
$439
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Fri 9/18
11:08 am-5:05 pm
1 stop6h 57m
Lambert-St Louis
Tue 9/22
6:53 am-11:20 am
1 stop3h 27m
$457
Myrtle BeachSt. Louis
MYR Myrtle Beach Intl - STL Lambert-St Louis
MYRSTL
Myrtle Beach Intl
Mon 9/14
6:40 am-11:35 am
1 stop5h 55m
Lambert-St Louis
Thu 9/17
11:40 am-7:45 pm
1 stop7h 05m
$459
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Myrtle Beach with our price prediction graph.
MYR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to St. Louis
What is the cheapest month to book a flight from Myrtle Beach to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to St. Louis (average of $296). Flying from Myrtle Beach to St. Louis in July is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to STL?
Find hourly flight availability from Myrtle Beach to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 3, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to St. Louis as you normally would.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 3, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to St. Louis, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
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Top 3 airlines flying from Myrtle Beach to St. Louis
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$267 | Average$351 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$351 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$325 | Average$401 | FlexibilityNo cancel fee | On-time63% |