$130+ Cheap flights from Myrtle Beach to St. Louis (MYR - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Jul 23 — Jul 301
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Myrtle Beach to St. LouisExplore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:23 pm
MYR
- STL
1 stop8h 19m
American Airlines
Mon 8/3110:22 am
STL
- MYR
1 stop5h 03m
American Airlines
Deal found 6/23![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:23 am
MYR
- STL
2 stops12h 37m
United Airlines
Tue 9/18:00 am
STL
- MYR
1 stop5h 53m
United Airlines
Deal found 6/23![United Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:15 pm
MYR
- STL
1 stop4h 50m
Southwest
Sat 7/184:45 pm
STL
- MYR
Nonstop1h 55m
Southwest
Deal found 6/19![Southwest logo]()
$306
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
MYR
- STL
1 stop4h 43m
Delta
Tue 7/287:08 am
STL
- MYR
1 stop4h 52m
Delta
Deal found 6/22![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:25 pm
MYR
- STL
2 stops6h 35m
Southwest
Tue 9/2210:45 am
STL
- MYR
2 stops7h 35m
Southwest
Deal found 6/23![Southwest logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:53 pm
MYR
- STL
2 stops36h 04m
Multiple Airlines
Tue 7/214:09 pm
STL
- MYR
1 stop15h 56m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:55 pm
MYR
- STL
Nonstop2h 05m
Southwest
Mon 8/316:05 am
STL
- MYR
1 stop6h 45m
Southwest
Deal found 6/23![Southwest logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:13 pm
MYR
- STL
1 stop8h 46m
Multiple Airlines
Fri 7/244:57 pm
STL
- MYR
2 stops27h 11m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:13 pm
MYR
- STL
1 stop8h 46m
Multiple Airlines
Thu 7/236:34 pm
STL
- MYR
2 stops19h 38m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$320
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:23 am
MYR
- STL
2 stops12h 37m
United Airlines
Mon 8/318:00 am
STL
- MYR
1 stop5h 53m
United Airlines
Deal found 6/23![United Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:53 pm
MYR
- STL
2 stops20h 44m
Multiple Airlines
Wed 7/224:09 pm
STL
- MYR
1 stop15h 46m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:30 pm
MYR
- STL
2 stops21h 07m
Multiple Airlines
Tue 7/214:09 pm
STL
- MYR
1 stop15h 56m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$330
Best flights from Myrtle Beach to St. LouisDiscover carefully curated flight deals from Myrtle Beach to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from Myrtle Beach to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:05 pm
MYR
- STL
1 stop5h 05m
Southwest
Sat 9/128:30 am
STL
- MYR
2 stops9h 30m
Southwest
Deal found 6/21![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
MYR
- STL
1 stop4h 43m
Delta
Tue 7/219:24 am
STL
- MYR
1 stop5h 03m
Delta
Deal found 6/21![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:10 pm
MYR
- STL
2 stops7h 06m
American Airlines
Mon 7/205:10 am
STL
- MYR
1 stop6h 19m
American Airlines
Deal found 6/19![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:25 pm
MYR
- STL
2 stops8h 45m
Southwest
Tue 9/221:40 pm
STL
- MYR
1 stop4h 30m
Southwest
Deal found 6/23![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:59 pm
MYR
- STL
1 stop4h 54m
Delta
Wed 7/226:00 am
STL
- MYR
1 stop6h 00m
Delta
Deal found 6/22![Delta logo]()
$307
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
MYR
- STL
1 stop4h 43m
Delta
Tue 7/287:08 am
STL
- MYR
1 stop4h 52m
Delta
Deal found 6/22![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:30 am
MYR
- STL
Nonstop2h 10m
Southwest
Tue 7/211:45 pm
STL
- MYR
1 stop5h 50m
Southwest
Deal found 6/20![Southwest logo]()
$382
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/127:59 pm
MYR
- STL
1 stop4h 54m
Delta
Mon 7/206:00 am
STL
- MYR
1 stop6h 00m
Delta
Deal found 6/21![Delta logo]()
$373
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:34 am
MYR
- STL
1 stop6h 50m
Delta
Mon 7/206:00 am
STL
- MYR
1 stop3h 47m
Delta
Deal found 6/21![Delta logo]()
$373
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:45 pm
MYR
- STL
1 stop6h 35m
Delta
Mon 7/206:58 pm
STL
- MYR
1 stop3h 57m
Delta
Deal found 6/20![Delta logo]()
$373
Last-minute flights from Myrtle Beach to St. LouisDiscover last-minute flight deals from Myrtle Beach to St. Louis. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to St. Louis. Data last updated June 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:53 pm
MYR
- STL
2 stops36h 04m
Multiple Airlines
Tue 7/214:09 pm
STL
- MYR
1 stop15h 56m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:53 pm
MYR
- STL
2 stops20h 44m
Multiple Airlines
Wed 7/224:09 pm
STL
- MYR
1 stop15h 46m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:30 pm
MYR
- STL
2 stops21h 07m
Multiple Airlines
Mon 7/204:09 pm
STL
- MYR
1 stop16h 56m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:30 pm
MYR
- STL
2 stops36h 27m
Multiple Airlines
Wed 7/224:09 pm
STL
- MYR
1 stop15h 46m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:15 pm
MYR
- STL
1 stop4h 50m
Southwest
Sat 7/184:45 pm
STL
- MYR
Nonstop1h 55m
Southwest
Deal found 6/19![Southwest logo]()
$306
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
MYR
- STL
1 stop4h 43m
Delta
Tue 7/287:08 am
STL
- MYR
1 stop4h 52m
Delta
Deal found 6/22![Delta logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:13 pm
MYR
- STL
1 stop8h 46m
Multiple Airlines
Fri 7/244:57 pm
STL
- MYR
2 stops27h 11m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:13 pm
MYR
- STL
1 stop8h 46m
Multiple Airlines
Thu 7/236:34 pm
STL
- MYR
2 stops19h 38m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:10 pm
MYR
- STL
2 stops9h 20m
Southwest
Tue 7/211:45 pm
STL
- MYR
1 stop5h 50m
Southwest
Deal found 6/19![Southwest logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:13 pm
MYR
- STL
1 stop8h 46m
Multiple Airlines
Wed 7/224:57 pm
STL
- MYR
2 stops23h 48m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:42 pm
MYR
- STL
1 stop10h 17m
Multiple Airlines
Fri 7/244:57 pm
STL
- MYR
2 stops27h 11m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:50 pm
MYR
- STL
1 stop7h 15m
Southwest
Sat 7/254:45 pm
STL
- MYR
Nonstop1h 55m
Southwest
Deal found 6/20![Southwest logo]()
$346
One-way flights from Myrtle Beach to St. LouisSearch for one-way flight options from Myrtle Beach to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from Myrtle Beach to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:58 pm
MYR
- STL
2 stops35h 59m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:30 pm
MYR
- STL
2 stops21h 07m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:58 pm
MYR
- STL
2 stops40h 42m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:25 pm
MYR
- STL
2 stops40h 15m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/214:13 pm
MYR
- STL
1 stop8h 46m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:30 pm
MYR
- STL
2 stops21h 52m
Frontier
Deal found 6/23![Frontier logo]()
$152
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:59 pm
MYR
- STL
1 stop5h 43m
Delta
Deal found 6/22![Delta logo]()
$154
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:23 am
MYR
- STL
2 stops12h 37m
United Airlines
Deal found 6/19![United Airlines logo]()
$155
Find flight deals from Myrtle Beach to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $130 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $350 |
Good round-trip deal | $465 or less |
Good one-way deal | $203 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Tue 9/8
5:05 pm-9:10 pm
1 stop5h 05m
Lambert-St Louis
Sat 9/12
8:30 am-7:00 pm
2 stops9h 30m
$304
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Wed 9/16
2:25 pm-10:10 pm
2 stops8h 45m
Lambert-St Louis
Tue 9/22
1:40 pm-7:10 pm
1 stop4h 30m
$304
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Tue 7/14
6:00 am-9:43 am
1 stop4h 43m
Lambert-St Louis
Tue 7/21
9:24 am-3:27 pm
1 stop5h 03m
$307
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Mon 7/13
7:59 pm-11:53 pm
1 stop4h 54m
Lambert-St Louis
Wed 7/22
6:00 am-1:00 pm
1 stop6h 00m
$307
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Tue 7/14
6:00 am-9:43 am
1 stop4h 43m
Lambert-St Louis
Tue 7/28
7:08 am-1:00 pm
1 stop4h 52m
$307
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Sun 7/12
7:59 pm-11:53 pm
1 stop4h 54m
Lambert-St Louis
Mon 7/20
6:00 am-1:00 pm
1 stop6h 00m
$373
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Thu 7/9
11:34 am-5:24 pm
1 stop6h 50m
Lambert-St Louis
Mon 7/20
6:00 am-10:47 am
1 stop3h 47m
$373
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Sat 7/11
5:45 pm-11:20 pm
1 stop6h 35m
Lambert-St Louis
Mon 7/20
6:58 pm-11:55 pm
1 stop3h 57m
$373
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 7/17
6:10 pm-12:16 am
2 stops7h 06m
Lambert-St Louis
Mon 7/20
5:10 am-12:29 pm
1 stop6h 19m
$378
Quickest round-trip
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Sun 7/12
6:30 am-7:40 am
Nonstop2h 10m
Lambert-St Louis
Tue 7/21
1:45 pm-8:35 pm
1 stop5h 50m
$382
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to St. Louis in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Myrtle Beach with our price prediction graph.
MYR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to St. Louis
What is the cheapest month to book a flight from Myrtle Beach to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to St. Louis (average of $225). Flying from Myrtle Beach to St. Louis in December is currently the most expensive (average of $616). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to STL?
Find hourly flight availability from Myrtle Beach to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 23, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to St. Louis as you normally would.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 23, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to St. Louis, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
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Myrtle Beach and St. Louis flights
Browse other Myrtle Beach and St. Louis flight options. Last updated on June 23, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
Top 3 airlines flying from Myrtle Beach to St. Louis
Discover the top 3 airlines that operate flights from Myrtle Beach to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$225 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$357 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$307 | Average$361 | FlexibilityNo cancel fee | On-time63% |