How popular is this Charleston to St. Louis flight route?

Flights from Charleston to Lambert-St Louis have been viewed 3 times in the past calendar month.

What are the cheapest airlines flying from Charleston to St. Louis round-trip?

Our cheapest airline available from Charleston to St. Louis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $224 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $245 and $316 round-trip. You may be able to fly from Charleston to St. Louis for 40% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Charleston to St. Louis one-way?

One-way options have recently been found by users for as low as $98 on Spirit Airlines. Other airlines that offer cheap prices include American Airlines from $119 and United Airlines from $139 one-way.

What are the cheapest flights from Charleston to St. Louis?

While on average a flight from Charleston to St. Louis is generally $373, our data shows the cheapest flight currently is $104. When looking at the most popular route, (Charleston - Lambert-St Louis), you can expect to pay $233 for that flight.

What are the most popular airlines that fly from Charleston to St. Louis?

The most popular airlines flying from Charleston to St. Louis are American Airlines, Delta and Southwest. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Charleston to St. Louis?

It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

How far in advance should I book a flight from Charleston to St. Louis?

Users have found that booking a flight from Charleston to St. Louis at least 50 days early can save you up to 29% on average compared to booking a flight this week. If booking 50 days before your flight isn’t an option for you, users have found flights from Charleston to St. Louis for as little as $244 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $244 for flights departing within the next 3 days.

What is the cheapest month to fly from Charleston to St. Louis?

The best pricing can be found in the month of July. Prices to St. Louis from Charleston average $374. You can even find prices in July for less than $374, as users have found deals to St. Louis from as low as $201. The month of February appears to be one of the more expensive times to travel to St. Louis from Charleston. Flying in the targeted month can save you up to 37%.

Most accurate provider : When it comes to deals on Charleston-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Charleston-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Charleston to St. Louis that include hotel bookings?

Yes. In addition to deals on Charleston to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Charleston to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to St. Louis.

Can I find deals for business class flights from Charleston to St. Louis?

Yes. Cheapflights offers flight deals from Charleston to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$98+ Flights from Charleston to St. Louis - Compare & Save Big

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Charleston to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Charleston to Lambert-St Louis are usually found in July or August, booked 80 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Charleston to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$224 (Mytrip)
One-way from	$98 (FlightHub)
Popular in	February
Cheapest in	July
Average price	$417
Good round-trip deal	$352 or less
Good one-way deal	$218 or less

Provider with most accurate pricing for Charleston-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Charleston-Lambert-St Louis flights.

Search Deals

From Charleston to Lambert-St Louis

Search Deals

One-way flight from Charleston to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($66 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in May 2025

Search Deals

Price to beat on a round-trip flight from Charleston to Lambert-St Louis.

Search Deals

Price to beat on a one-way flight from Charleston to Lambert-St Louis.

Search Deals

Find flight deals from Charleston to St. Louis

Cheapest flights from Charleston to St. Louis
Explore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

Thu 9/1110:28 amCHS - STL

1 stop22h 21mSpirit Airlines

Sun 9/148:44 amSTL - CHS

1 stop23h 49mSpirit Airlines

Deal found 5/22

$224

Tue 6/106:00 amCHS - STL

1 stop4h 26mAmerican Airlines

Wed 6/115:37 amSTL - CHS

1 stop5h 18mAmerican Airlines

Deal found 5/20

$237

Wed 6/115:15 amCHS - STL

1 stop4h 08mDelta

Wed 6/112:15 pmSTL - CHS

1 stop6h 49mDelta

Deal found 5/20

$287

Tue 6/107:45 pmCHS - STL

Nonstop2h 05mSouthwest

Wed 6/1111:20 amSTL - CHS

Nonstop1h 50mSouthwest

Deal found 5/20

$303

Fri 6/137:03 amCHS - STL

2 stops11h 01mMultiple Airlines

Sat 6/2112:15 pmSTL - CHS

3 stops33h 14mMultiple Airlines

Deal found 5/21

$330

Fri 6/1311:39 amCHS - STL

1 stop4h 51mUnited Airlines

Sat 6/213:40 pmSTL - CHS

2 stops7h 17mUnited Airlines

Deal found 5/21

$348

Wed 6/116:56 pmCHS - STL

2 stops14h 09mAlaska Airlines

Thu 6/127:32 pmSTL - CHS

2 stops15h 23mAlaska Airlines

Deal found 5/20

$976

Best flights from Charleston to St. Louis
Discover carefully curated flight deals from Charleston to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 23, 2025.

Thu 9/1110:28 amCHS - STL

1 stop22h 21mSpirit Airlines

Sun 9/148:44 amSTL - CHS

1 stop23h 49mSpirit Airlines

Deal found 5/22

$224

Tue 8/266:00 amCHS - STL

1 stop4h 30mAmerican Airlines

Thu 8/2810:16 amSTL - CHS

1 stop7h 47mAmerican Airlines

Deal found 5/22

$245

Fri 9/1211:25 amCHS - STL

Nonstop2h 05mSouthwest

Mon 9/157:50 amSTL - CHS

Nonstop1h 55mSouthwest

Deal found 5/22

$316

Wed 6/117:05 amCHS - STL

1 stop7h 21mDelta

Tue 6/249:28 amSTL - CHS

1 stop3h 28mDelta

Deal found 5/22

$352

Fri 9/123:35 pmCHS - STL

3 stops41h 14mMultiple Airlines

Mon 9/158:44 amSTL - CHS

2 stops22h 53mMultiple Airlines

Deal found 5/22

$399

Tue 6/105:50 amCHS - STL

1 stop5h 06mUnited Airlines

Tue 6/178:10 amSTL - CHS

2 stops9h 50mUnited Airlines

Deal found 5/22

$418

Last-minute flights from Charleston to St. Louis
Discover last-minute flight deals from Charleston to St. Louis. Data last updated May 23, 2025 and is based on user searches.

Wed 5/285:35 amCHS - STL

1 stop4h 25mDelta

Wed 5/281:09 pmSTL - CHS

1 stop4h 49mDelta

Deal found 5/21

$417

Wed 5/288:55 amCHS - STL

2 stops7h 55mSouthwest

Wed 5/285:00 pmSTL - CHS

1 stop3h 45mSouthwest

Deal found 5/21

$485

Fri 5/306:25 amCHS - STL

1 stop9h 46mAmerican Airlines

Mon 6/26:00 amSTL - CHS

1 stop5h 00mAmerican Airlines

Deal found 5/21

$382

Fri 5/3010:04 amCHS - STL

2 stops13h 41mUnited Airlines

Mon 6/25:00 amSTL - CHS

1 stop4h 36mUnited Airlines

Deal found 5/21

$487

Fri 5/302:03 pmCHS - STL

2 stops20h 12mMultiple Airlines

Mon 6/29:50 amSTL - CHS

3 stops34h 56mMultiple Airlines

Deal found 5/21

$527

Fri 6/62:03 pmCHS - STL

2 stops20h 12mSpirit Airlines

Sun 6/810:10 amSTL - CHS

2 stops25h 58mSpirit Airlines

Deal found 5/21

$350

Tue 6/106:00 amCHS - STL

1 stop4h 26mAmerican Airlines

Wed 6/115:37 amSTL - CHS

1 stop5h 18mAmerican Airlines

Deal found 5/20

$237

Tue 6/107:00 pmCHS - STL

1 stop4h 55mSouthwest

Wed 6/1111:20 amSTL - CHS

Nonstop1h 50mSouthwest

Deal found 5/20

$303

Wed 6/115:15 amCHS - STL

1 stop4h 08mDelta

Wed 6/112:15 pmSTL - CHS

1 stop6h 49mDelta

Deal found 5/20

$287

Wed 6/116:56 pmCHS - STL

2 stops14h 09mAlaska Airlines

Thu 6/127:32 pmSTL - CHS

2 stops15h 23mAlaska Airlines

Deal found 5/20

$976

Fri 6/137:03 amCHS - STL

2 stops11h 01mMultiple Airlines

Sat 6/2112:15 pmSTL - CHS

3 stops33h 14mMultiple Airlines

Deal found 5/21

$330

Fri 6/1311:39 amCHS - STL

1 stop4h 51mUnited Airlines

Sat 6/213:40 pmSTL - CHS

2 stops7h 17mUnited Airlines

Deal found 5/21

$348

One-way flights from Charleston to St. Louis
Search for one-way flight options from Charleston to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 23, 2025.

Mon 6/231:10 pmCHS - STL

1 stop6h 08mSpirit Airlines

Deal found 5/21

$98

Wed 7/91:29 pmCHS - STL

1 stop7h 50mAmerican Airlines

Deal found 5/21

$119

Tue 7/222:44 pmCHS - STL

2 stops9h 01mUnited Airlines

Deal found 5/21

$139

Wed 7/97:45 pmCHS - STL

Nonstop2h 05mSouthwest

Deal found 5/22

$144

Sat 6/289:42 amCHS - STL

3 stops33h 59mMultiple Airlines

Deal found 5/21

$185

Mon 7/146:23 pmCHS - STL

1 stop6h 30mDelta

Deal found 5/21

$187

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 9/11

10:28 am-7:49 am

1 stop22h 21m

Lambert-St Louis

Sun 9/14

8:44 am-9:33 am

1 stop23h 49m

$224

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 6/10

6:00 am-9:26 am

1 stop4h 26m

Lambert-St Louis

Wed 6/11

5:37 am-11:55 am

1 stop5h 18m

$237

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 6/11

5:15 am-8:23 am

1 stop4h 08m

Lambert-St Louis

Wed 6/11

2:15 pm-10:04 pm

1 stop6h 49m

$287

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 6/10

7:45 pm-8:50 pm

Nonstop2h 05m

Lambert-St Louis

Wed 6/11

11:20 am-2:10 pm

Nonstop1h 50m

$303

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 6/13

7:03 am-5:04 pm

2 stops11h 01m

Lambert-St Louis

Sat 6/21

12:15 pm-10:29 pm

3 stops33h 14m

$330

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 6/13

11:39 am-3:30 pm

1 stop4h 51m

Lambert-St Louis

Sat 6/21

3:40 pm-11:57 pm

2 stops7h 17m

$348

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 6/11

6:56 pm-8:05 am

2 stops14h 09m

Lambert-St Louis

Thu 6/12

7:32 pm-11:55 am

2 stops15h 23m

$976

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Mon 6/23

1:10 pm-6:18 pm

1 stop6h 08m

$98

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 7/8

8:38 pm-11:59 pm

1 stop4h 21m

$119

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 7/22

2:44 pm-10:45 pm

2 stops9h 01m

$139

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/21

Showing 1-10 of 13 results

Compare providers for flights from Charleston to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to St. Louis in May.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Charleston-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Charleston-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Charleston with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to St. Louis

How far ahead should I book a flight from Charleston to St. Louis?

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Charleston to St. Louis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Charleston to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Charleston to St. Louis (average of $311). Flying from Charleston to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to STL?

A simple way to save on the total cost of your ticket is to fly from Charleston to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 46% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Charleston to St. Louis?

Travelers seeking maximum savings on their Charleston to St. Louis flight should consider departing on Thursday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest, Delta and United Airlines from Charleston to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,291 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Southwest

8.0

Very good

4,291 reviews

Southwest

8.0

Very good

4,291 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Delta

8.0

Very good

7,950 reviews

Southwest

8.0

Very good

4,291 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

United Airlines

7.4

Good

8,745 reviews

Southwest

8.0

Very good

4,291 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,291 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Spirit Airlines

6.3

Okay

8,004 reviews

Southwest

8.0

Very good

4,291 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

How popular is this Charleston to St. Louis flight route?
Flights from Charleston to Lambert-St Louis have been viewed 3 times in the past calendar month.
What are the cheapest airlines flying from Charleston to St. Louis round-trip?
Our cheapest airline available from Charleston to St. Louis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $224 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $245 and $316 round-trip. You may be able to fly from Charleston to St. Louis for 40% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Charleston to St. Louis one-way?
One-way options have recently been found by users for as low as $98 on Spirit Airlines. Other airlines that offer cheap prices include American Airlines from $119 and United Airlines from $139 one-way.
What are the cheapest flights from Charleston to St. Louis?
While on average a flight from Charleston to St. Louis is generally $373, our data shows the cheapest flight currently is $104. When looking at the most popular route, (Charleston - Lambert-St Louis), you can expect to pay $233 for that flight.
Can I find deals for flights from Charleston to St. Louis that include hotel bookings?
Yes. In addition to deals on Charleston to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Charleston to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to St. Louis.
Can I find deals for business class flights from Charleston to St. Louis?
Yes. Cheapflights offers flight deals from Charleston to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Charleston to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Charleston to St. Louis (average of $311). Flying from Charleston to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Maryland Heights

Fairview Heights

Collinsville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

O'Fallon

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Charleston to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$172	Average$349	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$232	Average$382	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$316	Average$368	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$98+ Cheap flights from Charleston to St. Louis (CHS - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Charleston to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Charleston to Lambert-St Louis are usually found in July or August, booked 80 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Charleston to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Charleston to St. Louis

Cheapest flights from Charleston to St. LouisExplore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

Explore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Compare providers for flights from Charleston to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to St. Louis in May.

Best time to book a flight from Charleston to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Charleston with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Charleston to St. Louis

How far ahead should I book a flight from Charleston to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Charleston to St. Louis. Price data was last updated on May 16, 2025.

What is the cheapest month to book a flight from Charleston to St. Louis?

What is the cheapest time of day to fly from CHS to STL?

Find hourly flight availability from Charleston to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 23, 2025.

What is the cheapest day to fly from Charleston to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Charleston to St. Louis. Price data was last updated on December 16, 2024.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest, Delta and United Airlines from Charleston to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Charleston to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Charleston to St. Louis flight route?

What are the cheapest airlines flying from Charleston to St. Louis round-trip?

What are the cheapest airlines to fly from Charleston to St. Louis one-way?

What are the cheapest flights from Charleston to St. Louis?

Can I find deals for flights from Charleston to St. Louis that include hotel bookings?

How can I find direct flights from Charleston to St. Louis?

Can I find deals for business class flights from Charleston to St. Louis?

What is the cheapest month to book a flight from Charleston to St. Louis?

Traveling to a place near Charleston?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charleston to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Charleston to St. Louis
Explore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.