$114+ Cheap flights from Charleston to St. Louis (CHS - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to St. Louis
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Best
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One-way
Cheapest flights from Charleston to St. LouisExplore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:45 am -
2 stops29h 32m
Mon 12/76:20 pm -
1 stop13h 18m
Deal found 10/22![Multiple Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:55 pm -
1 stop5h 15m
Wed 11/113:10 pm -
1 stop5h 30m
Deal found 10/22![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:30 am -
2 stops7h 15m
Wed 11/1110:55 am -
2 stops8h 10m
Deal found 10/21![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop5h 40m
Thu 12/1012:40 pm -
1 stop6h 25m
Deal found 10/22![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:20 am -
1 stop4h 40m
Tue 11/107:18 pm -
1 stop3h 41m
Deal found 10/22![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:15 pm -
1 stop4h 00m
Mon 11/306:30 pm -
1 stop4h 45m
Deal found 10/23![Southwest logo]()
$305
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:04 pm -
1 stop5h 52m
Wed 11/186:00 am -
1 stop5h 52m
Deal found 10/22![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:20 am -
1 stop4h 43m
Sun 11/157:13 am -
1 stop4h 39m
Deal found 10/22![Delta logo]()
$351
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:10 pm -
1 stop7h 04m
Sat 11/287:26 am -
1 stop6h 51m
Deal found 10/21![American Airlines logo]()
$353
Best flights from Charleston to St. LouisDiscover carefully curated flight deals from Charleston to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Charleston to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:25 pm -
1 stop4h 35m
Wed 11/1110:55 am -
1 stop4h 35m
Deal found 10/21![Southwest logo]()
$263
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:32 pm -
1 stop4h 26m
Sun 11/155:29 pm -
1 stop5h 48m
Deal found 10/23![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:29 pm -
1 stop4h 54m
Sun 11/156:00 am -
2 stops7h 28m
Deal found 10/23![United Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:59 pm -
1 stop4h 56m
Mon 12/287:15 pm -
1 stop3h 39m
Deal found 10/25![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:30 pm -
1 stop5h 45m
Sun 11/156:40 am -
1 stop5h 40m
Deal found 10/23![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:30 pm -
1 stop5h 35m
Thu 12/1010:55 am -
2 stops8h 10m
Deal found 10/22![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:29 pm -
1 stop7h 11m
Mon 11/238:00 am -
1 stop5h 28m
Deal found 10/25![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:15 pm -
1 stop4h 00m
Mon 11/306:30 pm -
1 stop4h 45m
Deal found 10/23![Southwest logo]()
$305
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:52 pm -
2 stops7h 48m
Sat 11/285:00 am -
1 stop5h 21m
Deal found 10/20![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:00 am -
2 stops9h 10m
Mon 11/236:40 am -
1 stop5h 35m
Deal found 10/25![Southwest logo]()
$392
Last-minute flights from Charleston to St. LouisDiscover last-minute flight deals from Charleston to St. Louis. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to St. Louis. Data last updated October 25, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:55 pm -
1 stop5h 15m
Wed 11/113:10 pm -
1 stop5h 30m
Deal found 10/22![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:30 am -
2 stops7h 15m
Wed 11/1110:55 am -
2 stops8h 10m
Deal found 10/21![Southwest logo]()
$273
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:20 am -
1 stop4h 40m
Tue 11/107:18 pm -
1 stop3h 41m
Deal found 10/22![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:20 am -
1 stop4h 43m
Sun 11/157:13 am -
1 stop4h 39m
Deal found 10/22![Delta logo]()
$351
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:29 pm -
1 stop4h 54m
Sun 11/156:00 am -
2 stops7h 28m
Deal found 10/23![United Airlines logo]()
$356
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:04 pm -
1 stop5h 52m
Wed 11/186:00 am -
1 stop5h 52m
Deal found 10/22![Delta logo]()
$335
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:29 pm -
1 stop7h 11m
Mon 11/238:00 am -
1 stop5h 28m
Deal found 10/25![United Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:10 pm -
1 stop7h 04m
Sat 11/287:26 am -
1 stop6h 51m
Deal found 10/21![American Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:50 pm -
2 stops25h 50m
Mon 11/306:05 pm -
1 stop13h 33m
Deal found 10/23![Multiple Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:15 pm -
1 stop4h 00m
Mon 11/306:30 pm -
1 stop4h 45m
Deal found 10/23![Southwest logo]()
$305
One-way flights from Charleston to St. LouisSearch for one-way flight options from Charleston to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Charleston to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:45 am -
2 stops29h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:45 am -
3 stops12h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
2 stops12h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$127
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:55 pm -
1 stop5h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$132
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:35 am -
2 stops8h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:00 am -
2 stops35h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$202
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:20 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$221
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:52 pm -
2 stops7h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:10 pm -
3 stops43h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:13 pm -
2 stops20h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$235
Find flight deals from Charleston to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $250 (Kiwi.com) |
One-way from | $114 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $322 |
Good one-way deal | $234 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Thu 12/10
6:45 am-11:17 am
3 stops29h 32m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Wed 11/11
6:00 am-5:42 pm
2 stops12h 42m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$127
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Thu 12/10
5:15 pm-10:15 pm
1 stop6h 00m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$132
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Thu 11/19
5:15 pm-10:15 pm
1 stop6h 00m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$132
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Mon 11/9
7:55 pm-12:10 am
1 stop5h 15m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$132
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Mon 12/21
4:55 pm-12:15 am
2 stops8h 20m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$137
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Sun 11/22
7:00 am-5:40 pm
2 stops35h 40m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$202
Quickest round-trip
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Sun 11/22
5:20 am-9:00 am
1 stop4h 40m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$221
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Mon 11/9
2:52 pm-9:40 pm
2 stops7h 48m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$222
CharlestonSt. Louis
CHS Charleston - STL Lambert-St Louis
CHSSTL
Charleston
Mon 12/21
4:10 pm-10:53 am
3 stops43h 43m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$225
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Charleston to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Charleston with our price prediction graph.
CHS-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to St. Louis
What is the cheapest month to book a flight from Charleston to St. Louis?
Currently, February is the cheapest month in which you can book a flight from Charleston to St. Louis (average of $276). Flying from Charleston to St. Louis in June is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHS to STL?
Find hourly flight availability from Charleston to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
A simple way to save on the total cost of your ticket is to fly from Charleston to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 25, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Charleston to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.4
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.4
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Charleston to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
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Charleston and St. Louis flights
Browse other Charleston and St. Louis flight options. Last updated on October 25, 2026.
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Top 3 airlines flying from Charleston to St. Louis
Discover the top 3 airlines that operate flights from Charleston to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$351 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$274 | Average$361 | FlexibilityNo cancel fee | On-time71% |