$109+ Cheap flights from Charleston (CHS) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
May 30 — Jun 61
Round-trip
1 adult, Economy
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Cheapest flights from Charleston to MissouriExplore the most affordable flight options available from Charleston to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
Explore the most affordable flight options available from Charleston to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:13 pm
CHS
- STL
1 stop6h 16m
American Airlines
Wed 6/109:23 am
STL
- CHS
1 stop7h 16m
American Airlines
Deal found 4/27![American Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:15 pm
CHS
- STL
Nonstop2h 15m
Southwest
Tue 5/263:45 pm
STL
- CHS
1 stop4h 20m
Southwest
Deal found 4/30![Southwest logo]()
$233
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:19 pm
CHS
- STL
1 stop5h 40m
American Airlines
Tue 5/266:12 pm
STL
- CHS
1 stop4h 36m
American Airlines
Deal found 4/30![American Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:59 pm
CHS
- STL
1 stop5h 00m
Delta
Wed 5/206:45 am
STL
- CHS
1 stop4h 34m
Delta
Deal found 4/26![Delta logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:25 am
CHS
- STL
2 stops9h 50m
Multiple Airlines
Tue 5/264:19 pm
STL
- CHS
1 stop16h 19m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$252
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:31 am
CHS
- STL
1 stop5h 15m
United Airlines
Wed 6/246:00 am
STL
- CHS
2 stops7h 27m
United Airlines
Deal found 4/28![United Airlines logo]()
$256
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:21 pm
CHS
- STL
1 stop5h 29m
United Airlines
Sat 5/301:13 pm
STL
- CHS
1 stop7h 38m
United Airlines
Deal found 4/25![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:15 pm
CHS
- STL
1 stop6h 45m
Southwest
Wed 6/243:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Deal found 4/28![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:59 pm
CHS
- STL
1 stop5h 00m
Delta
Mon 5/257:05 am
STL
- CHS
1 stop4h 05m
Delta
Deal found 4/27![Delta logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:53 pm
CHS
- STL
1 stop9h 56m
Multiple Airlines
Tue 6/234:17 pm
STL
- CHS
1 stop16h 21m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:40 pm
CHS
- STL
1 stop7h 15m
Southwest
Tue 6/233:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Deal found 4/26![Southwest logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:23 pm
CHS
- STL
1 stop9h 46m
Multiple Airlines
Mon 6/154:17 pm
STL
- CHS
1 stop15h 21m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$278
Best flights from Charleston to MissouriDiscover carefully curated flight deals from Charleston to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
Discover carefully curated flight deals from Charleston to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:59 pm
CHS
- STL
1 stop4h 57m
Delta
Tue 6/236:00 am
STL
- CHS
1 stop5h 04m
Delta
Deal found 4/25![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:31 am
CHS
- SGF
1 stop7h 29m
United Airlines
Sat 5/302:54 pm
SGF
- CHS
1 stop6h 21m
United Airlines
Deal found 4/25![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:00 am
CHS
- STL
1 stop7h 10m
Southwest
Tue 6/233:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Deal found 4/29![Southwest logo]()
$315
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:26 pm
CHS
- COU
1 stop6h 51m
American Airlines
Sun 6/76:50 am
COU
- CHS
1 stop7h 02m
American Airlines
Deal found 4/28![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:15 am
CHS
- SGF
1 stop6h 12m
Delta
Wed 5/276:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/28![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
CHS
- STL
1 stop7h 11m
United Airlines
Sat 6/61:13 pm
STL
- CHS
1 stop7h 38m
United Airlines
Deal found 4/29![United Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:15 am
CHS
- SGF
1 stop6h 12m
Delta
Wed 5/276:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/28![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:31 am
CHS
- SGF
1 stop7h 35m
United Airlines
Tue 7/146:00 am
SGF
- CHS
2 stops7h 27m
United Airlines
Deal found 4/29![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:35 pm
CHS
- STL
1 stop4h 35m
Southwest
Fri 6/2610:00 am
STL
- CHS
2 stops7h 55m
Southwest
Deal found 4/29![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:24 pm
CHS
- SGF
1 stop4h 45m
Delta
Mon 6/226:58 pm
SGF
- CHS
1 stop4h 38m
Delta
Deal found 4/29![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:25 am
CHS
- SGF
1 stop6h 24m
American Airlines
Mon 6/296:12 pm
SGF
- CHS
1 stop4h 47m
American Airlines
Deal found 4/25![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:15 am
CHS
- STL
1 stop4h 35m
Southwest
Fri 7/32:15 pm
STL
- CHS
2 stops6h 20m
Southwest
Deal found 4/25![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:03 pm
CHS
- SGF
1 stop5h 16m
Delta
Wed 5/276:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/28![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:45 am
CHS
- MCI
1 stop5h 10m
Southwest
Tue 7/77:20 am
MCI
- CHS
1 stop7h 15m
Southwest
Deal found 4/29![Southwest logo]()
$393
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:15 am
CHS
- STL
1 stop4h 31m
Delta
Fri 7/33:57 pm
STL
- CHS
1 stop4h 02m
Delta
Deal found 4/25![Delta logo]()
$337
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:44 pm
CHS
- STL
1 stop6h 12m
Delta
Mon 7/612:35 pm
STL
- CHS
1 stop8h 24m
Delta
Deal found 4/26![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:45 pm
CHS
- MCI
1 stop6h 55m
Southwest
Thu 6/45:15 am
MCI
- CHS
1 stop5h 10m
Southwest
Deal found 4/27![Southwest logo]()
$427
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:59 pm
CHS
- STL
1 stop4h 57m
Delta
Thu 6/257:12 pm
STL
- CHS
1 stop4h 24m
Delta
Deal found 4/26![Delta logo]()
$337
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:00 pm
CHS
- MCI
1 stop6h 42m
United Airlines
Mon 8/316:00 am
MCI
- CHS
1 stop7h 54m
United Airlines
Deal found 4/27![United Airlines logo]()
$517
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:35 am
CHS
- MCI
2 stops7h 55m
Southwest
Wed 7/85:20 am
MCI
- CHS
2 stops7h 10m
Southwest
Deal found 4/29![Southwest logo]()
$433
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:03 pm
CHS
- STL
1 stop4h 35m
Delta
Sun 5/247:05 am
STL
- CHS
1 stop5h 58m
Delta
Deal found 4/27![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:35 am
CHS
- MCI
2 stops7h 55m
Southwest
Fri 6/261:00 pm
MCI
- CHS
2 stops7h 35m
Southwest
Deal found 4/29![Southwest logo]()
$465
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:20 pm
CHS
- COU
1 stop7h 33m
American Airlines
Fri 5/154:28 pm
COU
- CHS
1 stop5h 38m
American Airlines
Deal found 4/26![American Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:15 am
CHS
- SGF
1 stop6h 12m
Delta
Tue 5/266:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/26![Delta logo]()
$386
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:15 pm
CHS
- MCI
2 stops7h 35m
Southwest
Sun 5/317:10 am
MCI
- CHS
1 stop12h 00m
Southwest
Deal found 4/28![Southwest logo]()
$468
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:08 pm
CHS
- COU
1 stop5h 55m
United Airlines
Fri 5/83:10 pm
COU
- CHS
1 stop27h 29m
United Airlines
Deal found 4/29![United Airlines logo]()
$666
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:15 am
CHS
- STL
1 stop4h 29m
Delta
Sun 5/177:05 am
STL
- CHS
1 stop6h 02m
Delta
Deal found 4/27![Delta logo]()
$386
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:25 pm
CHS
- MCI
2 stops9h 05m
Southwest
Sun 5/249:10 am
MCI
- CHS
2 stops9h 00m
Southwest
Deal found 4/28![Southwest logo]()
$487
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:40 am
CHS
- COU
1 stop5h 52m
United Airlines
Fri 5/83:10 pm
COU
- CHS
1 stop21h 41m
United Airlines
Deal found 4/29![United Airlines logo]()
$666
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:17 pm
CHS
- SGF
1 stop5h 47m
Delta
Sun 5/244:00 pm
SGF
- CHS
1 stop6h 59m
Delta
Deal found 4/28![Delta logo]()
$399
Last-minute flights from Charleston to MissouriDiscover last-minute flight deals from Charleston to Missouri. Data last updated April 30, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Missouri. Data last updated April 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:15 am
CHS
- STL
1 stop5h 29m
Delta
Mon 5/257:01 pm
STL
- CHS
1 stop3h 58m
Delta
Deal found 4/27![Delta logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:34 pm
CHS
- STL
2 stops25h 20m
Multiple Airlines
Sat 5/234:19 pm
STL
- CHS
1 stop15h 19m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:53 pm
CHS
- STL
1 stop10h 28m
Multiple Airlines
Sun 5/176:55 pm
STL
- CHS
2 stops36h 43m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$288
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/164:55 pm
CHS
- SGF
1 stop6h 24m
Delta
Wed 5/276:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/26![Delta logo]()
$308
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:59 pm
CHS
- STL
1 stop5h 00m
Delta
Wed 5/206:45 am
STL
- CHS
1 stop4h 34m
Delta
Deal found 4/26![Delta logo]()
$247
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:59 pm
CHS
- STL
1 stop5h 00m
Delta
Mon 5/257:05 am
STL
- CHS
1 stop4h 05m
Delta
Deal found 4/27![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:15 am
CHS
- SGF
1 stop6h 12m
Delta
Tue 5/266:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/26![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:15 am
CHS
- SGF
1 stop6h 12m
Delta
Wed 5/276:49 pm
SGF
- CHS
1 stop4h 10m
Delta
Deal found 4/28![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:13 pm
CHS
- SGF
1 stop22h 00m
Multiple Airlines
Sat 5/236:36 pm
SGF
- CHS
1 stop13h 02m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:30 pm
CHS
- STL
1 stop8h 29m
American Airlines
Wed 5/276:12 pm
STL
- CHS
1 stop4h 36m
American Airlines
Deal found 4/29![American Airlines logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:21 pm
CHS
- STL
1 stop5h 29m
United Airlines
Sat 5/301:13 pm
STL
- CHS
1 stop7h 38m
United Airlines
Deal found 4/25![United Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:44 pm
CHS
- STL
1 stop9h 13m
Multiple Airlines
Sat 5/305:27 pm
STL
- CHS
2 stops28h 48m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$287
One-way flights from Charleston to MissouriSearch for one-way flight options from Charleston to Missouri. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
Search for one-way flight options from Charleston to Missouri. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:40 pm
CHS
- STL
Nonstop2h 20m
Southwest
Deal found 4/29![Southwest logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:50 pm
CHS
- STL
2 stops37h 05m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$113
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:00 am
CHS
- STL
1 stop4h 33m
American Airlines
Deal found 4/29![American Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:33 pm
CHS
- MCI
2 stops21h 48m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$118
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:15 pm
CHS
- STL
Nonstop2h 15m
Southwest
Deal found 4/27![Southwest logo]()
$120
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:03 pm
CHS
- STL
1 stop6h 15m
Delta
Deal found 4/28![Delta logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:34 pm
CHS
- STL
2 stops25h 59m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:53 pm
CHS
- STL
1 stop9h 56m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:33 pm
CHS
- MCI
2 stops49h 48m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:53 pm
CHS
- STL
1 stop10h 04m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$129
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:42 pm
CHS
- STL
1 stop6h 17m
American Airlines
Deal found 4/29![American Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:25 am
CHS
- STL
2 stops11h 05m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$131
Find flight deals from Charleston to Missouri
Keep the following information in mind while searching for Charleston to Missouri flight deals. Data was last updated April 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (American Airlines) |
One-way from | $109 (Southwest) |
Popular in | November |
Cheapest in | February |
Average price | $359 |
Good round-trip deal | $381 or less |
Good one-way deal | $179 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Charleston to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonSt. Louis
CHS - STL
CHSSTL
Charleston
Thu 6/18
7:59 pm-11:56 pm
1 stop4h 57m
Lambert-St Louis
Tue 6/23
6:00 am-12:04 pm
1 stop5h 04m
$282
CharlestonSpringfield
CHS - SGF
CHSSGF
Charleston
Thu 5/28
11:31 am-6:00 pm
1 stop7h 29m
Springfield-Branson
Sat 5/30
2:54 pm-10:15 pm
1 stop6h 21m
$303
CharlestonSpringfield
CHS - SGF
CHSSGF
Charleston
Wed 5/20
6:15 am-11:27 am
1 stop6h 12m
Springfield-Branson
Wed 5/27
6:49 pm-11:59 pm
1 stop4h 10m
$309
CharlestonSpringfield
CHS - SGF
CHSSGF
Charleston
Tue 5/19
6:15 am-11:27 am
1 stop6h 12m
Springfield-Branson
Wed 5/27
6:49 pm-11:59 pm
1 stop4h 10m
$309
CharlestonSt. Louis
CHS - STL
CHSSTL
Charleston
Thu 6/18
8:00 am-2:10 pm
1 stop7h 10m
Lambert-St Louis
Tue 6/23
3:15 pm-6:15 pm
Nonstop2h 00m
$315
CharlestonSpringfield
CHS - SGF
CHSSGF
Charleston
Fri 6/19
6:24 pm-10:09 pm
1 stop4h 45m
Springfield-Branson
Mon 6/22
6:58 pm-12:36 am
1 stop4h 38m
$317
CharlestonSt. Louis
CHS - STL
CHSSTL
Charleston
Tue 6/2
6:00 am-12:11 pm
1 stop7h 11m
Lambert-St Louis
Sat 6/6
1:13 pm-9:51 pm
1 stop7h 38m
$323
CharlestonSpringfield
CHS - SGF
CHSSGF
Charleston
Sat 5/16
6:03 pm-10:19 pm
1 stop5h 16m
Springfield-Branson
Wed 5/27
6:49 pm-11:59 pm
1 stop4h 10m
$324
Quickest round-trip
CharlestonSt. Louis
CHS - STL
CHSSTL
Charleston
Fri 7/3
6:15 am-9:46 am
1 stop4h 31m
Lambert-St Louis
Fri 7/3
3:57 pm-8:59 pm
1 stop4h 02m
$337
CharlestonSt. Louis
CHS - STL
CHSSTL
Charleston
Fri 7/3
6:44 pm-11:56 pm
1 stop6h 12m
Lambert-St Louis
Mon 7/6
12:35 pm-9:59 pm
1 stop8h 24m
$337
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from Charleston to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Charleston with our price prediction graph.
CHS-STL
CHS-MCI
CHS-COU
CHS-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Missouri
CHS-USMO
CHS-STL
CHS-MCI
CHS-COU
CHS-SGF
What is the cheapest month to book a flight from Charleston to Missouri?
Currently, August is the cheapest month in which you can book a flight from Charleston to Missouri (average of $182). Flying from Charleston to Missouri in December is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHS to MO?
Find hourly flight availability from Charleston to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2026.
One of the essential ways to save on airfare from Charleston to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 24% on airfare.
How much does it cost to fly round-trip from Charleston to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 30, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Charleston to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Charleston to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Missouri by cabin class
Find flights from Charleston to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Missouri flights
Browse other Charleston and Missouri flight options. Last updated on April 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Charleston to Missouri flights
Consider these flights traveling from Charleston to Missouri.
Top 3 airlines flying from Charleston to Missouri
Discover the top 3 airlines that operate flights from Charleston to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$224 | Average$360 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$226 | Average$429 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$246 | Average$419 | FlexibilityNo cancel fee | On-timeN/A |