$114+ Cheap flights from Missouri to Charleston (CHS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to CharlestonExplore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop5h 59m
Mon 12/216:15 am -
1 stop6h 37m
Deal found 10/30![Delta logo]()
$227
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:02 am -
1 stop5h 28m
Mon 12/74:19 pm -
1 stop6h 58m
Deal found 10/29![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:55 am -
1 stop4h 35m
Mon 12/76:35 am -
2 stops8h 10m
Deal found 10/29![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:20 pm -
1 stop5h 46m
Tue 12/156:19 am -
1 stop5h 41m
Deal found 10/28![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:27 am -
1 stop6h 59m
Mon 12/76:00 am -
1 stop5h 08m
Deal found 10/28![American Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:55 pm -
1 stop8h 20m
Wed 12/28:00 am -
1 stop6h 15m
Deal found 10/26![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop6h 46m
Thu 12/310:23 am -
2 stops8h 53m
Deal found 10/28![United Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:45 am -
2 stops8h 55m
Thu 12/36:35 am -
2 stops8h 10m
Deal found 10/28![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
2 stops7h 28m
Wed 12/212:15 pm -
1 stop5h 21m
Deal found 10/26![United Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:04 pm -
1 stop11h 34m
Tue 11/244:50 pm -
1 stop22h 35m
Deal found 10/28![Multiple Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:58 pm -
1 stop7h 06m
Mon 12/145:10 am -
1 stop6h 55m
Deal found 10/28![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
2 stops8h 32m
Mon 12/145:00 pm -
1 stop5h 47m
Deal found 10/28![United Airlines logo]()
$326
Best flights from Missouri to CharlestonDiscover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:55 am -
1 stop4h 35m
Mon 12/76:35 am -
2 stops8h 10m
Deal found 10/29![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/226:59 pm -
1 stop4h 03m
Sun 1/247:37 pm -
1 stop4h 49m
Deal found 10/29![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:00 am -
1 stop4h 39m
Fri 1/14:11 pm -
1 stop6h 27m
Deal found 10/27![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops8h 39m
Wed 11/187:00 pm -
1 stop4h 58m
Deal found 10/30![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/181:40 pm -
2 stops7h 20m
Mon 12/214:55 pm -
2 stops6h 50m
Deal found 10/30![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/105:30 am -
1 stop5h 05m
Wed 2/175:30 am -
1 stop5h 05m
Deal found 10/25![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:55 pm -
1 stop6h 04m
Thu 11/197:00 pm -
1 stop5h 10m
Deal found 10/29![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:40 am -
2 stops6h 40m
Thu 12/177:55 pm -
1 stop5h 15m
Deal found 10/29![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/138:00 am -
1 stop4h 47m
Tue 2/165:30 am -
1 stop5h 05m
Deal found 10/25![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:26 am -
1 stop7h 52m
Thu 11/269:00 am -
1 stop6h 35m
Deal found 10/29![American Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:50 pm -
1 stop4h 35m
Mon 12/289:15 pm -
1 stop4h 00m
Deal found 10/26![Southwest logo]()
$365
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/95:30 am -
1 stop5h 05m
Wed 2/177:40 am -
1 stop6h 45m
Deal found 10/27![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:30 am -
1 stop5h 16m
Sat 1/99:46 am -
1 stop5h 48m
Deal found 10/29![United Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/143:30 pm -
1 stop6h 25m
Sun 4/187:30 am -
1 stop4h 41m
Deal found 10/26![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:35 am -
1 stop5h 10m
Fri 1/11:30 pm -
2 stops6h 55m
Deal found 10/28![Southwest logo]()
$370
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:05 pm -
2 stops9h 54m
Thu 11/127:00 am -
1 stop5h 35m
Deal found 10/28![American Airlines logo]()
$460
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:00 pm -
1 stop6h 00m
Mon 11/92:52 pm -
2 stops9h 06m
Deal found 10/29![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/611:30 am -
2 stops6h 40m
Wed 1/1310:50 am -
1 stop4h 00m
Deal found 10/25![Southwest logo]()
$370
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1410:35 am -
1 stop5h 16m
Sat 2/204:30 pm -
1 stop5h 35m
Deal found 10/28![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:45 am -
1 stop8h 15m
Sat 1/912:36 pm -
1 stop5h 44m
Deal found 10/28![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:40 am -
1 stop5h 40m
Fri 12/186:45 pm -
1 stop6h 25m
Deal found 10/26![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1410:35 am -
1 stop4h 04m
Tue 2/162:25 pm -
1 stop4h 07m
Deal found 10/28![Delta logo]()
$400
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1312:55 pm -
1 stop7h 05m
Fri 12/189:15 pm -
1 stop4h 30m
Deal found 10/26![Southwest logo]()
$392
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1410:35 am -
1 stop4h 04m
Wed 2/172:25 pm -
1 stop4h 07m
Deal found 10/26![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:20 am -
2 stops11h 39m
Thu 11/127:00 am -
2 stops14h 41m
Deal found 10/27![United Airlines logo]()
$499
Last-minute flights from Missouri to CharlestonDiscover last-minute flight deals from Missouri to Charleston. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Charleston. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:26 pm -
1 stop4h 51m
Mon 11/167:26 pm -
1 stop4h 16m
Deal found 10/28![American Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:36 am -
1 stop10h 25m
Tue 11/173:00 pm -
2 stops29h 47m
Deal found 10/28![Multiple Airlines logo]()
$368
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops8h 39m
Wed 11/187:00 pm -
1 stop4h 58m
Deal found 10/30![United Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:46 am -
1 stop10h 15m
Thu 11/1910:13 pm -
1 stop19h 47m
Deal found 10/28![Multiple Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:54 pm -
1 stop4h 05m
Sat 11/214:07 pm -
1 stop7h 03m
Deal found 10/25![Delta logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:04 pm -
1 stop11h 34m
Tue 11/244:50 pm -
1 stop22h 35m
Deal found 10/28![Multiple Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:15 pm -
1 stop10h 00m
Sun 11/228:55 pm -
1 stop4h 20m
Deal found 10/26![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:55 pm -
1 stop8h 20m
Wed 12/28:00 am -
1 stop6h 15m
Deal found 10/26![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop5h 28m
Thu 12/36:00 am -
1 stop7h 22m
Deal found 10/28![United Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:45 am -
2 stops8h 55m
Thu 12/36:35 am -
2 stops8h 10m
Deal found 10/28![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
2 stops7h 28m
Wed 12/212:15 pm -
1 stop5h 21m
Deal found 10/26![United Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:26 am -
1 stop6h 51m
Sat 12/55:27 pm -
1 stop6h 15m
Deal found 10/29![American Airlines logo]()
$353
One-way flights from Missouri to CharlestonSearch for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:06 am -
1 stop4h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:02 pm -
2 stops19h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:58 pm -
1 stop18h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$125
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:35 pm -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$151
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:13 am -
1 stop3h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Delta logo]()
$151
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:00 am -
2 stops8h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$156
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
2 stops8h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$161
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:14 am -
1 stop4h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/811:06 am -
3 stops43h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$167
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:42 am -
1 stop8h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/811:30 am -
2 stops6h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:20 pm -
3 stops41h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$190
Find flight deals from Missouri to Charleston
Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $114 (Delta) |
Popular in | October |
Cheapest in | February |
Average price | $440 |
Good round-trip deal | $469 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Wed 12/9
10:06 am-3:10 pm
1 stop4h 04m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$114
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Wed 12/9
12:02 pm-8:38 am
2 stops19h 36m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$123
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Fri 11/13
12:58 pm-8:38 am
1 stop18h 40m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$125
Kansas CityCharleston
MCI Kansas City - CHS Charleston
MCICHS
Kansas City
Sat 11/21
6:35 pm-11:55 pm
1 stop4h 20m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$151
Kansas CityCharleston
MCI Kansas City - CHS Charleston
MCICHS
Kansas City
Mon 11/23
5:40 am-12:52 pm
1 stop6h 12m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$151
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Thu 12/10
5:02 am-11:30 am
1 stop5h 28m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$151
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Mon 11/23
5:00 am-2:28 pm
2 stops8h 28m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$156
ColumbiaCharleston
COU Columbia Regional - CHS Charleston
COUCHS
Columbia Regional
Thu 11/26
7:14 am-12:35 pm
1 stop4h 21m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$164
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Fri 1/8
11:30 am-7:10 pm
2 stops6h 40m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$188
Kansas CityCharleston
MCI Kansas City - CHS Charleston
MCICHS
Kansas City
Sat 11/21
8:29 pm-8:38 am
2 stops11h 09m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$202
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Missouri to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
STL-CHS
MCI-CHS
COU-CHS
SGF-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Charleston
USMO-CHS
STL-CHS
MCI-CHS
COU-CHS
SGF-CHS
What is the cheapest month to book a flight from Missouri to Charleston?
Currently, January is the cheapest month in which you can book a flight from Missouri to Charleston (average of $349). Flying from Missouri to Charleston in April is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to CHS?
Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Charleston as you normally would.
How much does it cost to fly round-trip from Missouri to Charleston?
Airfare is below average for this route at the moment.
Missouri to Charleston flights typically cost between $323 and $565 in December.The cheapest round-trip price found within the last 5 days was $227 on Southwest (Dec 18-Dec 21).
How far ahead should I book a flight from Missouri to Charleston?
Booking 86 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Charleston flight routes
Complete your trip
Flights by cabin class
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Top destinations
Alternative routes for Missouri to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Charleston by cabin class
Find flights from Missouri to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Charleston flights
Browse other Missouri and Charleston flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Charleston flights
Consider these flights traveling from Missouri to Charleston.
Top 4 airlines flying from Missouri to Charleston
Discover the top 4 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$404 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$245 | Average$449 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$263 | Average$430 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$270 | Average$427 | FlexibilityNo cancel fee | On-time71% |