$98+ Cheap flights from Missouri to Charleston (CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
Aug 31 — Sep 71
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to CharlestonExplore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:30 pm
STL
- CHS
Nonstop1h 55m
Southwest
Thu 10/221:25 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 7/28![Southwest logo]()
$217
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:40 pm
STL
- CHS
Nonstop2h 00m
Southwest
Tue 9/2210:45 am
CHS
- STL
1 stop6h 40m
Southwest
Deal found 7/30![Southwest logo]()
$222
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:46 pm
STL
- CHS
1 stop5h 13m
Delta
Tue 9/225:25 am
CHS
- STL
1 stop6h 30m
Delta
Deal found 7/30![Delta logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:02 pm
STL
- CHS
1 stop14h 36m
Multiple Airlines
Sat 9/58:56 pm
CHS
- STL
2 stops21h 26m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:50 pm
STL
- CHS
2 stops5h 55m
Southwest
Wed 8/265:10 pm
CHS
- STL
1 stop5h 00m
Southwest
Deal found 7/28![Southwest logo]()
$232
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:40 pm
STL
- CHS
Nonstop2h 00m
Southwest
Sat 9/56:45 am
CHS
- STL
Nonstop2h 00m
Southwest
Deal found 8/1![Southwest logo]()
$236
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
STL
- CHS
1 stop4h 54m
Delta
Sun 9/67:13 am
CHS
- STL
1 stop5h 43m
Delta
Deal found 7/29![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:35 pm
STL
- CHS
Nonstop2h 00m
Southwest
Fri 9/255:20 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 8/1![Southwest logo]()
$247
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:30 pm
STL
- CHS
Nonstop1h 55m
Southwest
Tue 10/68:10 am
CHS
- STL
1 stop4h 25m
Southwest
Deal found 7/27![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am
STL
- CHS
1 stop6h 00m
Delta
Tue 11/36:00 am
CHS
- STL
1 stop5h 51m
Delta
Deal found 8/1![Delta logo]()
$251
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:22 pm
COU
- CHS
1 stop5h 02m
American Airlines
Thu 11/124:59 pm
CHS
- COU
1 stop6h 43m
American Airlines
Deal found 7/30![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:19 am
COU
- CHS
2 stops11h 40m
United Airlines
Sat 10/36:50 pm
CHS
- COU
1 stop5h 05m
United Airlines
Deal found 7/30![United Airlines logo]()
$314
Best flights from Missouri to CharlestonDiscover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
Discover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
STL
- CHS
1 stop4h 54m
Delta
Sun 9/67:13 am
CHS
- STL
1 stop5h 43m
Delta
Deal found 7/28![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:35 pm
STL
- CHS
Nonstop2h 00m
Southwest
Mon 9/286:30 pm
CHS
- STL
1 stop4h 40m
Southwest
Deal found 7/30![Southwest logo]()
$252
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:03 pm
SGF
- CHS
1 stop5h 31m
United Airlines
Wed 8/194:30 pm
CHS
- SGF
1 stop8h 12m
United Airlines
Deal found 7/31![United Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:41 pm
SGF
- CHS
1 stop6h 18m
American Airlines
Thu 9/1712:22 pm
CHS
- SGF
1 stop5h 42m
American Airlines
Deal found 7/28![American Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:04 pm
SGF
- CHS
1 stop11h 34m
Multiple Airlines
Sun 10/187:05 am
CHS
- SGF
2 stops27h 50m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm
STL
- CHS
Nonstop1h 55m
Southwest
Wed 10/288:10 am
CHS
- STL
1 stop4h 25m
Southwest
Deal found 7/31![Southwest logo]()
$261
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm
STL
- CHS
1 stop5h 24m
Delta
Mon 10/197:10 pm
CHS
- STL
1 stop5h 44m
Delta
Deal found 7/31![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm
STL
- CHS
Nonstop1h 55m
Southwest
Mon 10/196:40 pm
CHS
- STL
1 stop6h 55m
Southwest
Deal found 7/31![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:25 pm
STL
- CHS
Nonstop1h 55m
Southwest
Sat 10/317:45 am
CHS
- STL
2 stops9h 00m
Southwest
Deal found 7/29![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:03 pm
SGF
- CHS
1 stop5h 01m
United Airlines
Tue 1/124:50 pm
CHS
- SGF
1 stop5h 38m
United Airlines
Deal found 7/30![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:00 am
STL
- CHS
1 stop5h 00m
Delta
Sun 10/115:30 am
CHS
- STL
1 stop4h 39m
Delta
Deal found 7/27![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:25 pm
STL
- CHS
1 stop4h 50m
Southwest
Sat 10/2412:00 pm
CHS
- STL
2 stops8h 55m
Southwest
Deal found 7/31![Southwest logo]()
$291
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:12 pm
COU
- CHS
1 stop5h 22m
United Airlines
Tue 9/14:38 pm
CHS
- COU
1 stop7h 17m
United Airlines
Deal found 7/31![United Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:05 am
MCI
- CHS
1 stop4h 13m
Delta
Mon 11/92:04 pm
CHS
- MCI
1 stop7h 09m
Delta
Deal found 7/27![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:00 am
STL
- CHS
1 stop5h 52m
Delta
Sat 8/226:00 am
CHS
- STL
1 stop4h 20m
Delta
Deal found 7/27![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:02 am
JLN
- CHS
1 stop5h 56m
United Airlines
Sat 1/96:05 am
CHS
- JLN
1 stop7h 14m
United Airlines
Deal found 7/31![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:40 pm
STL
- CHS
Nonstop2h 00m
Southwest
Sat 8/226:45 am
CHS
- STL
Nonstop2h 00m
Southwest
Deal found 7/27![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:00 pm
COU
- CHS
1 stop5h 41m
United Airlines
Thu 11/1210:23 am
CHS
- COU
2 stops12h 15m
United Airlines
Deal found 8/1![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:18 pm
MCI
- CHS
1 stop5h 41m
Delta
Mon 8/312:17 pm
CHS
- MCI
1 stop5h 44m
Delta
Deal found 7/31![Delta logo]()
$387
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:10 pm
MCI
- CHS
1 stop4h 30m
Southwest
Mon 10/198:05 pm
CHS
- MCI
1 stop5h 20m
Southwest
Deal found 7/29![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:08 pm
MCI
- CHS
1 stop7h 26m
United Airlines
Tue 9/811:37 am
CHS
- MCI
1 stop5h 35m
United Airlines
Deal found 7/28![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:44 pm
MCI
- CHS
1 stop4h 15m
Delta
Mon 10/124:20 pm
CHS
- MCI
1 stop4h 55m
Delta
Deal found 7/29![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:25 am
MCI
- CHS
2 stops7h 10m
Southwest
Mon 11/25:30 am
CHS
- MCI
1 stop5h 30m
Southwest
Deal found 7/27![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:15 am
COU
- CHS
2 stops7h 35m
United Airlines
Sun 9/136:30 am
CHS
- COU
1 stop5h 09m
United Airlines
Deal found 7/28![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:05 am
MCI
- CHS
1 stop6h 10m
Delta
Fri 10/95:35 pm
CHS
- MCI
1 stop5h 20m
Delta
Deal found 7/30![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:00 pm
STL
- CHS
1 stop7h 40m
Southwest
Sun 10/189:00 pm
CHS
- STL
1 stop3h 55m
Southwest
Deal found 7/31![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am
MCI
- CHS
1 stop5h 54m
Delta
Sun 11/155:20 am
CHS
- MCI
1 stop5h 02m
Delta
Deal found 7/28![Delta logo]()
$400
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:25 am
MCI
- CHS
2 stops6h 50m
Southwest
Thu 11/196:35 am
CHS
- MCI
2 stops8h 00m
Southwest
Deal found 7/30![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
SGF
- CHS
2 stops7h 50m
United Airlines
Thu 9/174:58 pm
CHS
- SGF
1 stop7h 23m
United Airlines
Deal found 7/28![United Airlines logo]()
$450
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:15 am
MCI
- CHS
2 stops10h 25m
Southwest
Mon 10/266:35 am
CHS
- MCI
1 stop4h 20m
Southwest
Deal found 7/27![Southwest logo]()
$386
Last-minute flights from Missouri to CharlestonDiscover last-minute flight deals from Missouri to Charleston. Data last updated August 1, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Charleston. Data last updated August 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
COU
- CHS
1 stop6h 44m
American Airlines
Mon 8/174:06 pm
CHS
- COU
1 stop6h 59m
American Airlines
Deal found 7/29![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:15 am
COU
- CHS
2 stops7h 55m
United Airlines
Mon 8/176:30 am
CHS
- COU
1 stop4h 44m
United Airlines
Deal found 7/29![United Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:00 am
COU
- CHS
1 stop6h 42m
American Airlines
Tue 8/187:00 am
CHS
- COU
1 stop6h 13m
American Airlines
Deal found 7/30![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:03 pm
SGF
- CHS
1 stop5h 31m
United Airlines
Wed 8/194:30 pm
CHS
- SGF
1 stop8h 12m
United Airlines
Deal found 7/31![United Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:36 am
STL
- CHS
1 stop7h 06m
American Airlines
Wed 8/267:50 pm
CHS
- STL
1 stop5h 24m
American Airlines
Deal found 7/28![American Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:50 pm
STL
- CHS
2 stops5h 55m
Southwest
Wed 8/265:10 pm
CHS
- STL
1 stop5h 00m
Southwest
Deal found 7/28![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:07 am
MCI
- CHS
1 stop5h 04m
Delta
Wed 8/262:17 pm
CHS
- MCI
1 stop5h 44m
Delta
Deal found 7/29![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:52 pm
STL
- CHS
1 stop6h 52m
Delta
Sun 8/236:15 am
CHS
- STL
1 stop4h 39m
Delta
Deal found 7/28![Delta logo]()
$263
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:15 am
STL
- CHS
1 stop4h 35m
Southwest
Fri 8/285:20 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 7/28![Southwest logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:02 pm
STL
- CHS
1 stop14h 36m
Multiple Airlines
Sat 9/58:56 pm
CHS
- STL
2 stops21h 26m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:40 pm
STL
- CHS
Nonstop2h 00m
Southwest
Sat 9/56:45 am
CHS
- STL
Nonstop2h 00m
Southwest
Deal found 8/1![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:40 pm
STL
- CHS
Nonstop2h 00m
Southwest
Mon 8/315:20 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 8/1![Southwest logo]()
$255
One-way flights from Missouri to CharlestonSearch for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
Search for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:29 pm
STL
- CHS
2 stops41h 09m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm
STL
- CHS
2 stops37h 51m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:17 pm
STL
- CHS
2 stops14h 20m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:17 pm
STL
- CHS
2 stops38h 20m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:26 am
MCI
- CHS
2 stops21h 11m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$109
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:35 pm
STL
- CHS
Nonstop2h 00m
Southwest
Deal found 7/28![Southwest logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:26 am
MCI
- CHS
2 stops21h 11m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:17 pm
STL
- CHS
2 stops37h 21m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:35 am
STL
- CHS
2 stops21h 03m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$112
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am
STL
- CHS
1 stop5h 22m
Delta
Deal found 7/28![Delta logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:26 am
MCI
- CHS
2 stops20h 12m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:26 am
MCI
- CHS
2 stops44h 12m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$117
Find flight deals from Missouri to Charleston
Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated August 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $217 (Southwest) |
One-way from | $98 (Kiwi.com) |
Popular in | July |
Cheapest in | August |
Average price | $320 |
Good round-trip deal | $443 or less |
Good one-way deal | $444 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Wed 9/2
6:00 am-11:54 am
1 stop4h 54m
Charleston
Sun 9/6
7:13 am-11:56 am
1 stop5h 43m
$237
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 9/24
3:35 pm-6:35 pm
Nonstop2h 00m
Charleston
Mon 9/28
6:30 pm-10:10 pm
1 stop4h 40m
$252
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Mon 10/26
4:30 pm-7:25 pm
Nonstop1h 55m
Charleston
Wed 10/28
8:10 am-11:35 am
1 stop4h 25m
$261
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Fri 10/16
4:30 pm-7:25 pm
Nonstop1h 55m
Charleston
Mon 10/19
6:40 pm-12:35 am
1 stop6h 55m
$276
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Fri 10/16
5:35 pm-11:59 pm
1 stop5h 24m
Charleston
Mon 10/19
7:10 pm-11:54 pm
1 stop5h 44m
$281
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Sun 10/25
5:25 pm-8:20 pm
Nonstop1h 55m
Charleston
Sat 10/31
7:45 am-3:45 pm
2 stops9h 00m
$287
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 10/22
6:25 pm-12:15 am
1 stop4h 50m
Charleston
Sat 10/24
12:00 pm-7:55 pm
2 stops8h 55m
$291
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 10/8
7:00 am-1:00 pm
1 stop5h 00m
Charleston
Sun 10/11
5:30 am-9:09 am
1 stop4h 39m
$338
Quickest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Sat 8/15
1:40 pm-4:40 pm
Nonstop2h 00m
Charleston
Sat 8/22
6:45 am-7:45 am
Nonstop2h 00m
$352
Kansas CityCharleston
MCI - CHS
MCICHS
Kansas City
Sat 11/7
8:05 am-1:18 pm
1 stop4h 13m
Charleston
Mon 11/9
2:04 pm-8:13 pm
1 stop7h 09m
$353
Showing 1-10 of 58 resultsSorted by cheapest first
Best time to book a flight from Missouri to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
STL-CHS
MCI-CHS
COU-CHS
SGF-CHS
JLN-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Charleston
USMO-CHS
STL-CHS
MCI-CHS
COU-CHS
SGF-CHS
What is the cheapest month to book a flight from Missouri to Charleston?
Currently, February is the cheapest month in which you can book a flight from Missouri to Charleston (average of $353). Flying from Missouri to Charleston in July is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to CHS?
Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 1, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Charleston as you normally would.
How much does it cost to fly round-trip from Missouri to Charleston?
Airfare is below average for this route at the moment.
Missouri to Charleston flights typically cost between $243 and $418 in October.The cheapest round-trip price found within the last 5 days was $217 on Southwest (Oct 19-Oct 22).
How far ahead should I book a flight from Missouri to Charleston?
Booking 49 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Charleston flight routes
Complete your trip
Flights by cabin class
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Popular flights
Top destinations
Alternative routes for Missouri to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Charleston by cabin class
Find flights from Missouri to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Charleston flights
Browse other Missouri and Charleston flight options. Last updated on August 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Charleston flights
Consider these flights traveling from Missouri to Charleston.
Top 4 airlines flying from Missouri to Charleston
Discover the top 4 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$256 | Average$438 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$258 | Average$426 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$270 | Average$412 | FlexibilityNo cancel fee | On-time71% |