$103+ Cheap flights from Missouri to Charleston (CHS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to CharlestonExplore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:05 am -
1 stop4h 15m
Thu 10/221:25 pm -
Nonstop2h 05m
Deal found 9/10![Southwest logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:05 pm -
1 stop13h 33m
Wed 12/163:42 pm -
1 stop9h 59m
Deal found 9/10![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:30 pm -
1 stop21h 08m
Tue 11/103:00 pm -
2 stops27h 40m
Deal found 9/10![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm -
1 stop15h 08m
Thu 10/222:13 pm -
1 stop10h 00m
Deal found 9/10![Multiple Airlines logo]()
$236
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:03 am -
1 stop3h 47m
Thu 12/1712:55 pm -
1 stop4h 29m
Deal found 9/10![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm -
Nonstop1h 55m
Thu 10/221:25 pm -
Nonstop2h 05m
Deal found 9/10![Southwest logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:05 pm -
1 stop13h 33m
Wed 12/163:42 pm -
1 stop9h 59m
Deal found 9/10![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:05 pm -
1 stop13h 33m
Mon 12/143:27 pm -
1 stop10h 14m
Deal found 9/10![Multiple Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/244:49 pm -
1 stop4h 48m
Tue 12/296:03 pm -
1 stop6h 52m
Deal found 9/10![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:30 pm -
Nonstop1h 55m
Fri 10/234:45 pm -
2 stops7h 55m
Deal found 9/10![Southwest logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop15h 08m
Wed 10/286:00 am -
2 stops12h 40m
Deal found 9/14![Multiple Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:05 am -
1 stop3h 55m
Wed 10/285:43 pm -
1 stop4h 34m
Deal found 9/14![Delta logo]()
$287
Best flights from Missouri to CharlestonDiscover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:03 am -
1 stop4h 56m
Mon 12/145:34 pm -
1 stop5h 04m
Deal found 9/10![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 am -
1 stop7h 30m
Mon 12/76:25 pm -
1 stop5h 00m
Deal found 9/14![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:37 am -
2 stops13h 22m
Mon 12/143:34 pm -
1 stop7h 41m
Deal found 9/10![United Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:08 pm -
1 stop5h 51m
Sat 10/243:45 pm -
1 stop7h 57m
Deal found 9/12![American Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:25 am -
2 stops8h 10m
Fri 11/137:10 pm -
1 stop6h 25m
Deal found 9/13![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:32 am -
2 stops10h 16m
Sat 10/246:00 am -
2 stops7h 09m
Deal found 9/14![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:27 pm -
1 stop5h 32m
Sun 10/115:30 am -
1 stop6h 23m
Deal found 9/14![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:37 pm -
1 stop7h 09m
Mon 10/56:50 pm -
1 stop5h 28m
Deal found 9/12![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:10 pm -
1 stop6h 05m
Fri 11/132:00 pm -
1 stop8h 20m
Deal found 9/13![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:00 am -
1 stop7h 30m
Mon 12/146:35 am -
2 stops7h 10m
Deal found 9/9![Southwest logo]()
$368
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:20 pm -
1 stop3h 39m
Sun 10/256:30 am -
1 stop3h 39m
Deal found 9/10![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:36 pm -
1 stop4h 16m
Sun 11/85:05 am -
1 stop5h 31m
Deal found 9/11![American Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:05 pm -
1 stop6h 16m
Wed 10/217:00 am -
2 stops12h 36m
Deal found 9/10![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:05 pm -
1 stop6h 16m
Sat 10/246:00 am -
2 stops9h 30m
Deal found 9/12![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:55 am -
2 stops8h 05m
Wed 12/161:30 pm -
2 stops6h 55m
Deal found 9/12![Southwest logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/63:00 pm -
1 stop6h 01m
Tue 2/96:00 am -
1 stop5h 55m
Deal found 9/10![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:46 pm -
1 stop7h 09m
Sat 11/284:08 pm -
1 stop7h 33m
Deal found 9/11![American Airlines logo]()
$521
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:44 pm -
1 stop4h 15m
Sun 10/255:30 am -
1 stop4h 59m
Deal found 9/13![Delta logo]()
$477
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:25 pm -
2 stops6h 35m
Mon 11/97:40 am -
2 stops12h 30m
Deal found 9/13![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:02 am -
1 stop5h 49m
Sat 1/94:00 pm -
1 stop8h 44m
Deal found 9/10![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:34 pm -
1 stop5h 25m
Sun 10/46:52 pm -
1 stop4h 16m
Deal found 9/11![Delta logo]()
$493
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:01 am -
2 stops11h 59m
Thu 11/127:00 pm -
1 stop4h 58m
Deal found 9/11![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:30 pm -
1 stop6h 00m
Sat 10/38:05 am -
2 stops9h 10m
Deal found 9/11![Southwest logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:19 pm -
1 stop5h 22m
Sat 10/33:00 pm -
2 stops8h 55m
Deal found 9/11![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:05 pm -
1 stop11h 30m
Sun 11/85:30 am -
2 stops6h 55m
Deal found 9/11![Southwest logo]()
$475
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:50 am -
2 stops11h 09m
Thu 10/154:58 pm -
1 stop6h 02m
Deal found 9/10![United Airlines logo]()
$448
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:50 pm -
2 stops13h 20m
Sun 10/257:55 pm -
1 stop5h 00m
Deal found 9/10![Southwest logo]()
$507
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:30 pm -
1 stop7h 16m
Sat 10/248:00 am -
1 stop5h 09m
Deal found 9/12![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop7h 27m
Tue 11/1711:12 am -
1 stop6h 05m
Deal found 9/13![United Airlines logo]()
$471
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:05 am -
1 stop5h 35m
Fri 9/256:35 am -
1 stop4h 40m
Deal found 9/11![Southwest logo]()
$590
Last-minute flights from Missouri to CharlestonDiscover last-minute flight deals from Missouri to Charleston. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Charleston. Data last updated September 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:44 am -
1 stop6h 32m
Sat 10/36:44 am -
1 stop5h 45m
Deal found 9/10![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:37 pm -
1 stop7h 09m
Mon 10/56:50 pm -
1 stop5h 28m
Deal found 9/11![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:22 pm -
1 stop4h 35m
Wed 10/214:34 pm -
1 stop6h 12m
Deal found 9/10![American Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm -
1 stop15h 08m
Thu 10/222:13 pm -
1 stop10h 00m
Deal found 9/10![Multiple Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:30 pm -
Nonstop1h 55m
Thu 10/221:25 pm -
Nonstop2h 05m
Deal found 9/10![Southwest logo]()
$246
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:08 pm -
1 stop5h 51m
Sat 10/243:45 pm -
1 stop7h 57m
Deal found 9/12![American Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:05 am -
1 stop4h 15m
Thu 10/221:25 pm -
Nonstop2h 05m
Deal found 9/10![Southwest logo]()
$227
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:14 pm -
1 stop5h 34m
Thu 10/226:00 am -
2 stops7h 13m
Deal found 9/10![United Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:30 pm -
1 stop21h 08m
Tue 11/103:00 pm -
2 stops27h 40m
Deal found 9/10![Multiple Airlines logo]()
$233
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:30 pm -
Nonstop1h 55m
Fri 10/234:45 pm -
2 stops7h 55m
Deal found 9/10![Southwest logo]()
$261
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:05 am -
1 stop3h 55m
Wed 10/285:43 pm -
1 stop4h 34m
Deal found 9/14![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop15h 08m
Wed 10/286:00 am -
2 stops12h 40m
Deal found 9/14![Multiple Airlines logo]()
$264
One-way flights from Missouri to CharlestonSearch for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:35 pm -
2 stops37h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:44 pm -
2 stops41h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:44 pm -
2 stops41h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$114
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:31 pm -
1 stop5h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:35 pm -
2 stops37h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:59 pm -
2 stops22h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:59 pm -
2 stops20h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:59 pm -
2 stops46h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:46 am -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$168
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:40 pm -
2 stops7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$177
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:34 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:14 pm -
2 stops8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$230
Find flight deals from Missouri to Charleston
Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $103 (Kiwi.com) |
Popular in | July |
Cheapest in | February |
Average price | $430 |
Good round-trip deal | $236 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Mon 11/9
5:00 pm-11:59 pm
1 stop5h 59m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Sat 10/31
10:47 am-3:28 pm
1 stop3h 41m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Tue 11/10
10:55 am-4:30 pm
1 stop4h 35m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Mon 12/7
6:00 am-12:59 pm
1 stop5h 59m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Sat 11/7
7:00 am-1:18 pm
1 stop5h 18m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$129
Quickest round-trip
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Fri 10/16
4:30 pm-7:25 pm
Nonstop1h 55m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$138
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Sat 11/7
5:00 am-5:39 pm
2 stops11h 39m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$164
Kansas CityCharleston
MCI Kansas City - CHS Charleston
MCICHS
Kansas City
Mon 11/9
12:40 pm-9:00 pm
2 stops7h 20m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$177
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Sat 12/12
2:33 pm-7:22 pm
1 stop3h 49m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$196
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Fri 10/9
4:30 pm-7:25 pm
Nonstop1h 55m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$196
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from Missouri to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
STL-CHS
MCI-CHS
COU-CHS
SGF-CHS
JLN-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Charleston
USMO-CHS
STL-CHS
MCI-CHS
COU-CHS
SGF-CHS
What is the cheapest month to book a flight from Missouri to Charleston?
Currently, February is the cheapest month in which you can book a flight from Missouri to Charleston (average of $353). Flying from Missouri to Charleston in April is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to CHS?
Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Charleston as you normally would.
How much does it cost to fly round-trip from Missouri to Charleston?
Airfare is below average for this route at the moment.
Missouri to Charleston flights typically cost between $336 and $435 in October.The cheapest round-trip price found within the last 5 days was $227 on Southwest (Oct 17-Oct 22).
How far ahead should I book a flight from Missouri to Charleston?
Booking 49 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Charleston flight routes
Complete your trip
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Alternative routes for Missouri to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Charleston by cabin class
Find flights from Missouri to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Charleston flights
Browse other Missouri and Charleston flight options. Last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Charleston flights
Consider these flights traveling from Missouri to Charleston.
Top 4 airlines flying from Missouri to Charleston
Discover the top 4 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$439 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$252 | Average$402 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$263 | Average$423 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$270 | Average$434 | FlexibilityNo cancel fee | On-time71% |