$111+ Cheap flights from Missouri to Charleston (CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — CHS
Jul 16 — Jul 231
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to CharlestonExplore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Wed 7/221:50 pm
CHS
- STL
Nonstop2h 10m
Southwest
Deal found 6/14![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:32 am
STL
- CHS
1 stop6h 09m
American Airlines
Wed 7/223:42 pm
CHS
- STL
1 stop7h 10m
American Airlines
Deal found 6/14![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:40 pm
STL
- CHS
Nonstop2h 00m
Southwest
Thu 8/135:20 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 6/15![Southwest logo]()
$245
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:42 am
STL
- CHS
1 stop8h 02m
American Airlines
Tue 8/256:00 am
CHS
- STL
1 stop5h 14m
American Airlines
Deal found 6/12![American Airlines logo]()
$246
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:00 am
STL
- CHS
1 stop5h 55m
Southwest
Sat 8/156:45 am
CHS
- STL
Nonstop2h 00m
Southwest
Deal found 6/12![Southwest logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/49:39 am
COU
- CHS
1 stop21h 59m
Multiple Airlines
Fri 7/103:23 pm
CHS
- COU
1 stop18h 26m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$255
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:53 pm
STL
- CHS
1 stop6h 05m
United Airlines
Thu 8/134:28 pm
CHS
- STL
1 stop7h 31m
United Airlines
Deal found 6/14![United Airlines logo]()
$255
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
STL
- CHS
2 stops7h 27m
United Airlines
Tue 8/1111:40 am
CHS
- STL
1 stop4h 58m
United Airlines
Deal found 6/13![United Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:20 am
MCI
- CHS
1 stop8h 00m
Southwest
Wed 9/26:45 am
CHS
- MCI
1 stop4h 00m
Southwest
Deal found 6/11![Southwest logo]()
$270
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:37 pm
MCI
- CHS
1 stop4h 28m
American Airlines
Wed 10/286:36 pm
CHS
- MCI
1 stop6h 30m
American Airlines
Deal found 6/11![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:40 am
STL
- CHS
1 stop8h 25m
Southwest
Mon 12/147:55 am
CHS
- STL
1 stop5h 45m
Southwest
Deal found 6/11![Southwest logo]()
$271
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:24 pm
COU
- CHS
1 stop4h 43m
American Airlines
Sat 11/147:30 am
CHS
- COU
1 stop6h 50m
American Airlines
Deal found 6/16![American Airlines logo]()
$298
Best flights from Missouri to CharlestonDiscover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
Discover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:20 am
MCI
- CHS
1 stop8h 00m
Southwest
Wed 9/26:45 am
CHS
- MCI
1 stop4h 00m
Southwest
Deal found 6/11![Southwest logo]()
$270
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
STL
- CHS
2 stops7h 27m
United Airlines
Fri 7/246:00 am
CHS
- STL
1 stop5h 34m
United Airlines
Deal found 6/14![United Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:51 am
STL
- CHS
1 stop4h 00m
Delta
Sun 11/155:55 pm
CHS
- STL
1 stop6h 44m
Delta
Deal found 6/15![Delta logo]()
$296
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:45 am
COU
- CHS
1 stop6h 16m
American Airlines
Wed 7/2212:44 pm
CHS
- COU
1 stop6h 17m
American Airlines
Deal found 6/16![American Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:07 pm
MCI
- CHS
2 stops25h 03m
Multiple Airlines
Thu 8/68:20 pm
CHS
- MCI
1 stop14h 30m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Thu 7/163:15 pm
CHS
- STL
1 stop7h 40m
Southwest
Deal found 6/12![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:15 am
COU
- CHS
2 stops7h 55m
United Airlines
Wed 8/264:28 pm
CHS
- COU
1 stop7h 27m
United Airlines
Deal found 6/14![United Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:30 pm
STL
- CHS
1 stop6h 20m
Southwest
Tue 7/143:00 pm
CHS
- STL
2 stops8h 30m
Southwest
Deal found 6/11![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
STL
- CHS
1 stop4h 43m
Delta
Thu 7/166:15 am
CHS
- STL
1 stop4h 28m
Delta
Deal found 6/13![Delta logo]()
$337
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:24 pm
COU
- CHS
1 stop4h 43m
American Airlines
Sat 11/147:30 am
CHS
- COU
1 stop6h 50m
American Airlines
Deal found 6/12![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:15 am
COU
- CHS
2 stops7h 55m
United Airlines
Tue 8/253:20 pm
CHS
- COU
2 stops8h 35m
United Airlines
Deal found 6/13![United Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:53 pm
SGF
- CHS
1 stop4h 33m
Delta
Tue 7/285:00 pm
CHS
- SGF
1 stop6h 10m
Delta
Deal found 6/12![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:45 pm
SGF
- CHS
1 stop6h 14m
American Airlines
Tue 10/62:36 pm
CHS
- SGF
1 stop4h 13m
American Airlines
Deal found 6/13![American Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Fri 7/244:45 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 6/14![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:59 pm
STL
- CHS
2 stops10h 00m
United Airlines
Wed 8/192:54 pm
CHS
- STL
2 stops8h 06m
United Airlines
Deal found 6/12![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:53 pm
SGF
- CHS
1 stop4h 33m
Delta
Sat 7/1110:40 am
CHS
- SGF
1 stop5h 40m
Delta
Deal found 6/15![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:25 am
STL
- CHS
2 stops7h 40m
Southwest
Mon 12/146:35 am
CHS
- STL
2 stops8h 15m
Southwest
Deal found 6/11![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:18 pm
STL
- CHS
2 stops9h 40m
United Airlines
Sat 8/156:30 am
CHS
- STL
1 stop6h 33m
United Airlines
Deal found 6/12![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:11 pm
SGF
- CHS
2 stops7h 40m
American Airlines
Sat 7/115:00 am
CHS
- SGF
1 stop6h 54m
American Airlines
Deal found 6/15![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:15 am
STL
- CHS
2 stops9h 15m
Southwest
Mon 7/134:10 pm
CHS
- STL
2 stops7h 45m
Southwest
Deal found 6/13![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:49 am
COU
- CHS
2 stops12h 03m
United Airlines
Sat 8/16:00 am
CHS
- COU
1 stop5h 13m
United Airlines
Deal found 6/12![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:32 am
SGF
- CHS
1 stop6h 27m
Delta
Sat 8/84:56 pm
CHS
- SGF
1 stop5h 23m
Delta
Deal found 6/11![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:20 am
MCI
- CHS
1 stop6h 55m
Southwest
Tue 8/116:45 am
CHS
- MCI
1 stop4h 00m
Southwest
Deal found 6/13![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:05 pm
SGF
- CHS
1 stop6h 06m
United Airlines
Sat 9/510:14 am
CHS
- SGF
2 stops11h 33m
United Airlines
Deal found 6/14![United Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:03 pm
SGF
- CHS
1 stop5h 01m
United Airlines
Tue 12/86:05 am
CHS
- SGF
2 stops10h 58m
United Airlines
Deal found 6/15![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:50 pm
MCI
- CHS
2 stops9h 15m
Southwest
Mon 10/265:30 am
CHS
- MCI
1 stop5h 35m
Southwest
Deal found 6/11![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:11 pm
COU
- CHS
1 stop5h 23m
United Airlines
Sat 8/296:30 am
CHS
- COU
1 stop4h 46m
United Airlines
Deal found 6/11![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2511:35 am
MCI
- CHS
1 stop6h 00m
Southwest
Tue 7/2810:45 am
CHS
- MCI
1 stop5h 10m
Southwest
Deal found 6/14![Southwest logo]()
$391
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:32 am
JLN
- CHS
1 stop5h 26m
United Airlines
Sat 9/268:00 am
CHS
- JLN
1 stop6h 31m
United Airlines
Deal found 6/11![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:40 am
MCI
- CHS
1 stop8h 05m
Southwest
Thu 10/293:15 pm
CHS
- MCI
2 stops9h 55m
Southwest
Deal found 6/13![Southwest logo]()
$392
Last-minute flights from Missouri to CharlestonDiscover last-minute flight deals from Missouri to Charleston. Data last updated June 16, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Charleston. Data last updated June 16, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:15 am
STL
- CHS
1 stop4h 55m
Southwest
Tue 7/141:50 pm
CHS
- STL
Nonstop2h 10m
Southwest
Deal found 6/14![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:39 pm
STL
- CHS
1 stop6h 08m
Delta
Tue 7/76:15 am
CHS
- STL
1 stop4h 28m
Delta
Deal found 6/14![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/49:39 am
COU
- CHS
1 stop21h 59m
Multiple Airlines
Fri 7/103:23 pm
CHS
- COU
1 stop18h 26m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$255
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:49 am
COU
- CHS
2 stops12h 09m
United Airlines
Fri 7/106:00 am
CHS
- COU
1 stop5h 13m
United Airlines
Deal found 6/13![United Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:15 am
STL
- CHS
1 stop4h 55m
Southwest
Mon 7/134:10 pm
CHS
- STL
2 stops7h 45m
Southwest
Deal found 6/13![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:45 am
COU
- CHS
1 stop6h 16m
American Airlines
Wed 7/2212:44 pm
CHS
- COU
1 stop6h 17m
American Airlines
Deal found 6/16![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
STL
- CHS
2 stops7h 27m
United Airlines
Sun 7/196:00 am
CHS
- STL
1 stop5h 34m
United Airlines
Deal found 6/15![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:49 am
COU
- CHS
2 stops12h 03m
United Airlines
Sat 8/16:00 am
CHS
- COU
1 stop5h 13m
United Airlines
Deal found 6/12![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Wed 7/221:50 pm
CHS
- STL
Nonstop2h 10m
Southwest
Deal found 6/14![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:32 am
STL
- CHS
1 stop6h 09m
American Airlines
Wed 7/223:42 pm
CHS
- STL
1 stop7h 10m
American Airlines
Deal found 6/14![American Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:19 pm
SGF
- CHS
1 stop13h 19m
Multiple Airlines
Tue 7/283:13 pm
CHS
- SGF
1 stop21h 47m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:25 am
STL
- CHS
1 stop8h 55m
Southwest
Wed 7/291:50 pm
CHS
- STL
Nonstop2h 10m
Southwest
Deal found 6/15![Southwest logo]()
$283
One-way flights from Missouri to CharlestonSearch for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
Search for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:00 am
STL
- CHS
1 stop6h 51m
Delta
Deal found 6/11![Delta logo]()
$111
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
STL
- CHS
1 stop5h 00m
Delta
Deal found 6/15![Delta logo]()
$114
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:30 am
STL
- CHS
2 stops8h 35m
Southwest
Deal found 6/11![Southwest logo]()
$117
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
STL
- CHS
1 stop6h 25m
Delta
Deal found 6/15![Delta logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:07 pm
MCI
- CHS
2 stops20h 01m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:57 pm
STL
- CHS
2 stops21h 11m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$124
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:39 pm
STL
- CHS
1 stop4h 05m
Delta
Deal found 6/12![Delta logo]()
$128
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
STL
- CHS
2 stops7h 27m
United Airlines
Deal found 6/11![United Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:07 pm
MCI
- CHS
2 stops22h 30m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:57 pm
STL
- CHS
2 stops23h 40m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$130
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:39 pm
STL
- CHS
1 stop4h 05m
Delta
Deal found 6/11![Delta logo]()
$133
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:20 am
MCI
- CHS
1 stop6h 55m
Southwest
Deal found 6/11![Southwest logo]()
$135
Find flight deals from Missouri to Charleston
Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated June 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $217 (Southwest) |
One-way from | $111 (Delta) |
Popular in | July |
Cheapest in | August |
Average price | $394 |
Good round-trip deal | $336 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityCharleston
MCI - CHS
MCICHS
Kansas City
Wed 8/26
9:20 am-6:20 pm
1 stop8h 00m
Charleston
Wed 9/2
6:45 am-9:45 am
1 stop4h 00m
$270
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 7/14
3:15 pm-6:15 pm
Nonstop2h 00m
Charleston
Thu 7/16
3:15 pm-9:55 pm
1 stop7h 40m
$277
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 7/21
6:00 am-2:27 pm
2 stops7h 27m
Charleston
Fri 7/24
6:00 am-10:34 am
1 stop5h 34m
$292
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 11/12
11:51 am-4:51 pm
1 stop4h 00m
Charleston
Sun 11/15
5:55 pm-11:39 pm
1 stop6h 44m
$296
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Sat 7/11
2:30 pm-9:50 pm
1 stop6h 20m
Charleston
Tue 7/14
3:00 pm-10:30 pm
2 stops8h 30m
$297
ColumbiaCharleston
COU - CHS
COUCHS
Columbia Regional
Wed 7/8
11:45 am-7:01 pm
1 stop6h 16m
Charleston
Wed 7/22
12:44 pm-6:01 pm
1 stop6h 17m
$298
ColumbiaCharleston
COU - CHS
COUCHS
Columbia Regional
Sat 8/22
6:15 am-3:10 pm
2 stops7h 55m
Charleston
Wed 8/26
4:28 pm-10:55 pm
1 stop7h 27m
$304
ColumbiaCharleston
COU - CHS
COUCHS
Columbia Regional
Fri 8/21
6:15 am-3:10 pm
2 stops7h 55m
Charleston
Tue 8/25
3:20 pm-10:55 pm
2 stops8h 35m
$313
Quickest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 7/21
3:15 pm-6:15 pm
Nonstop2h 00m
Charleston
Fri 7/24
4:45 pm-5:50 pm
Nonstop2h 05m
$326
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 8/18
12:59 pm-11:59 pm
2 stops10h 00m
Charleston
Wed 8/19
2:54 pm-10:00 pm
2 stops8h 06m
$327
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Missouri to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
MCI-CHS
STL-CHS
COU-CHS
SGF-CHS
JLN-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Charleston
USMO-CHS
MCI-CHS
STL-CHS
COU-CHS
SGF-CHS
What is the cheapest month to book a flight from Missouri to Charleston?
Currently, August is the cheapest month in which you can book a flight from Missouri to Charleston (average of $183). Flying from Missouri to Charleston in January is currently the most expensive (average of $336). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to CHS?
Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Charleston as you normally would.
How much does it cost to fly round-trip from Missouri to Charleston?
How far ahead should I book a flight from Missouri to Charleston?
Booking 50 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Charleston flight routes
Complete your trip
Flights by cabin class
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Popular flights
Top destinations
Alternative routes for Missouri to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 16, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Charleston by cabin class
Find flights from Missouri to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Charleston flights
Browse other Missouri and Charleston flight options. Last updated on June 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Charleston flights
Consider these flights traveling from Missouri to Charleston.
Top 4 airlines flying from Missouri to Charleston
Discover the top 4 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$206 | Average$385 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$237 | Average$415 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$243 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$516 | FlexibilityNo cancel fee | On-time69% |