$109+ Cheap flights from Missouri to Charleston (CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to CharlestonExplore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- CHS
1 stop4h 30m
Southwest
Tue 6/22:25 pm
CHS
- STL
1 stop7h 40m
Southwest
Deal found 4/28![Southwest logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- CHS
2 stops14h 05m
Multiple Airlines
Tue 6/210:38 am
CHS
- STL
1 stop14h 19m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:19 pm
STL
- CHS
1 stop16h 39m
Multiple Airlines
Fri 6/53:23 pm
CHS
- STL
1 stop9h 34m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$238
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:51 am
STL
- CHS
1 stop4h 42m
American Airlines
Sat 5/233:43 pm
CHS
- STL
1 stop6h 59m
American Airlines
Deal found 4/27![American Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:19 am
STL
- CHS
1 stop6h 34m
Delta
Mon 6/17:59 pm
CHS
- STL
1 stop5h 00m
Delta
Deal found 4/26![Delta logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
STL
- CHS
1 stop15h 29m
Multiple Airlines
Mon 6/13:23 pm
CHS
- STL
1 stop9h 34m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:10 pm
STL
- CHS
Nonstop1h 55m
Southwest
Sat 6/65:30 am
CHS
- STL
1 stop11h 15m
Southwest
Deal found 4/27![Southwest logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:09 pm
STL
- CHS
1 stop15h 29m
Multiple Airlines
Mon 8/243:23 pm
CHS
- STL
2 stops42h 29m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
SGF
- CHS
1 stop6h 41m
Delta
Wed 6/177:20 am
CHS
- SGF
1 stop4h 35m
Delta
Deal found 4/24![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:05 pm
COU
- CHS
1 stop5h 43m
United Airlines
Wed 9/23:25 pm
CHS
- COU
1 stop7h 24m
United Airlines
Deal found 4/28![United Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:35 am
MCI
- CHS
1 stop21h 03m
Multiple Airlines
Wed 6/104:33 pm
CHS
- MCI
2 stops49h 48m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
SGF
- CHS
1 stop6h 41m
Delta
Thu 6/187:20 am
CHS
- SGF
1 stop4h 35m
Delta
Deal found 4/24![Delta logo]()
$303
Best flights from Missouri to CharlestonDiscover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Missouri to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:27 pm
STL
- CHS
1 stop5h 57m
Delta
Sat 6/66:03 pm
CHS
- STL
1 stop6h 56m
Delta
Deal found 4/24![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:05 pm
COU
- CHS
1 stop5h 43m
United Airlines
Wed 9/23:25 pm
CHS
- COU
1 stop7h 24m
United Airlines
Deal found 4/28![United Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Thu 7/24:45 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 4/27![Southwest logo]()
$315
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:19 pm
COU
- CHS
1 stop5h 20m
American Airlines
Tue 5/2612:58 pm
CHS
- COU
2 stops9h 31m
American Airlines
Deal found 4/26![American Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
STL
- CHS
1 stop5h 10m
Delta
Mon 6/15:15 am
CHS
- STL
1 stop5h 29m
Delta
Deal found 4/24![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
SGF
- CHS
1 stop6h 41m
Delta
Wed 6/177:20 am
CHS
- SGF
1 stop4h 35m
Delta
Deal found 4/24![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:21 am
STL
- CHS
1 stop7h 41m
United Airlines
Wed 5/2010:15 am
CHS
- STL
2 stops9h 40m
United Airlines
Deal found 4/27![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Sat 7/411:00 am
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 4/24![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:08 pm
SGF
- CHS
1 stop4h 58m
Delta
Sat 6/275:03 pm
CHS
- SGF
1 stop5h 10m
Delta
Deal found 4/25![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:05 pm
COU
- CHS
1 stop5h 46m
United Airlines
Wed 6/246:00 am
CHS
- COU
1 stop5h 48m
United Airlines
Deal found 4/26![United Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:20 pm
STL
- CHS
1 stop6h 05m
Southwest
Mon 8/104:05 pm
CHS
- STL
1 stop8h 05m
Southwest
Deal found 4/27![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:58 pm
SGF
- CHS
1 stop4h 47m
Delta
Wed 6/176:24 pm
CHS
- SGF
1 stop4h 45m
Delta
Deal found 4/24![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:40 pm
STL
- CHS
1 stop4h 15m
Southwest
Fri 6/54:45 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 4/28![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:30 am
COU
- CHS
2 stops11h 23m
United Airlines
Sun 8/308:55 am
CHS
- COU
1 stop6h 35m
United Airlines
Deal found 4/28![United Airlines logo]()
$390
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:30 pm
SGF
- CHS
1 stop5h 17m
Delta
Sun 8/306:30 am
CHS
- SGF
1 stop5h 31m
Delta
Deal found 4/24![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:30 am
STL
- CHS
2 stops7h 05m
Southwest
Fri 7/1712:00 pm
CHS
- STL
1 stop8h 10m
Southwest
Deal found 4/28![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:05 pm
COU
- CHS
1 stop5h 43m
United Airlines
Wed 7/86:00 am
CHS
- COU
1 stop5h 48m
United Airlines
Deal found 4/26![United Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
STL
- CHS
1 stop5h 04m
Delta
Fri 7/106:24 pm
CHS
- STL
1 stop6h 29m
Delta
Deal found 4/25![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:10 pm
MCI
- CHS
2 stops5h 55m
Southwest
Wed 6/312:00 pm
CHS
- MCI
2 stops7h 10m
Southwest
Deal found 4/27![Southwest logo]()
$388
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:05 pm
COU
- CHS
1 stop5h 46m
United Airlines
Mon 6/226:00 am
CHS
- COU
1 stop5h 48m
United Airlines
Deal found 4/24![United Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:51 am
STL
- CHS
1 stop5h 27m
Delta
Fri 6/196:24 pm
CHS
- STL
1 stop6h 32m
Delta
Deal found 4/26![Delta logo]()
$337
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:05 pm
COU
- CHS
1 stop5h 46m
United Airlines
Mon 6/226:00 am
CHS
- COU
1 stop5h 48m
United Airlines
Deal found 4/24![United Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:58 pm
SGF
- CHS
1 stop4h 28m
Delta
Sun 7/265:10 am
CHS
- SGF
1 stop6h 42m
Delta
Deal found 4/24![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:10 am
MCI
- CHS
1 stop7h 20m
Southwest
Mon 10/266:30 am
CHS
- MCI
2 stops7h 45m
Southwest
Deal found 4/24![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:23 am
COU
- CHS
2 stops11h 29m
United Airlines
Tue 6/236:00 am
CHS
- COU
1 stop5h 48m
United Airlines
Deal found 4/24![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm
SGF
- CHS
1 stop5h 16m
Delta
Sun 10/255:55 pm
CHS
- SGF
1 stop5h 37m
Delta
Deal found 4/25![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:50 am
MCI
- CHS
2 stops7h 35m
Southwest
Sun 8/236:30 am
CHS
- MCI
1 stop4h 45m
Southwest
Deal found 4/28![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:20 am
MCI
- CHS
2 stops11h 33m
United Airlines
Wed 8/192:51 pm
CHS
- MCI
1 stop5h 26m
United Airlines
Deal found 4/28![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:50 am
MCI
- CHS
2 stops8h 50m
Southwest
Thu 8/2711:30 am
CHS
- MCI
2 stops6h 55m
Southwest
Deal found 4/24![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:53 pm
SGF
- CHS
1 stop4h 33m
Delta
Sun 7/125:00 pm
CHS
- SGF
1 stop6h 10m
Delta
Deal found 4/26![Delta logo]()
$396
Last-minute flights from Missouri to CharlestonDiscover last-minute flight deals from Missouri to Charleston. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Charleston. Data last updated April 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:35 am
MCI
- CHS
1 stop21h 13m
Multiple Airlines
Mon 5/185:47 pm
CHS
- MCI
2 stops48h 42m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:19 pm
STL
- CHS
1 stop15h 19m
Multiple Airlines
Thu 5/217:25 am
CHS
- STL
2 stops9h 50m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:51 am
STL
- CHS
1 stop4h 42m
American Airlines
Sat 5/233:43 pm
CHS
- STL
1 stop6h 59m
American Airlines
Deal found 4/27![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:19 pm
STL
- CHS
1 stop15h 19m
Multiple Airlines
Sat 5/303:44 pm
CHS
- STL
1 stop9h 13m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
STL
- CHS
1 stop5h 10m
Delta
Mon 6/15:15 am
CHS
- STL
1 stop5h 29m
Delta
Deal found 4/24![Delta logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 pm
STL
- CHS
2 stops28h 20m
Multiple Airlines
Mon 6/13:23 pm
CHS
- STL
1 stop9h 34m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:30 pm
STL
- CHS
1 stop4h 30m
Southwest
Tue 6/22:25 pm
CHS
- STL
1 stop7h 40m
Southwest
Deal found 4/28![Southwest logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- CHS
2 stops14h 05m
Multiple Airlines
Tue 6/210:38 am
CHS
- STL
1 stop14h 19m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$234
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:12 pm
SGF
- CHS
1 stop4h 36m
American Airlines
Tue 6/25:00 am
CHS
- SGF
1 stop6h 57m
American Airlines
Deal found 4/26![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:19 am
STL
- CHS
1 stop6h 34m
Delta
Mon 6/17:59 pm
CHS
- STL
1 stop5h 00m
Delta
Deal found 4/26![Delta logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
STL
- CHS
1 stop15h 29m
Multiple Airlines
Mon 6/13:23 pm
CHS
- STL
1 stop9h 34m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:00 am
STL
- CHS
1 stop7h 47m
Delta
Wed 6/310:43 am
CHS
- STL
1 stop6h 27m
Delta
Deal found 4/27![Delta logo]()
$282
One-way flights from Missouri to CharlestonSearch for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Missouri to Charleston. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Deal found 4/28![Southwest logo]()
$109
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:57 pm
STL
- CHS
1 stop4h 02m
Delta
Deal found 4/25![Delta logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- CHS
2 stops14h 05m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$118
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:49 am
STL
- CHS
1 stop5h 25m
Delta
Deal found 4/29![Delta logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:27 pm
STL
- CHS
2 stops23h 08m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
STL
- CHS
1 stop15h 29m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$127
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:14 am
STL
- CHS
1 stop5h 54m
American Airlines
Deal found 4/27![American Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:16 pm
MCI
- CHS
2 stops27h 31m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 pm
STL
- CHS
2 stops28h 20m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$133
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:05 am
STL
- CHS
1 stop4h 05m
Delta
Deal found 4/29![Delta logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:35 am
MCI
- CHS
1 stop21h 03m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:16 pm
MCI
- CHS
2 stops27h 59m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$148
Find flight deals from Missouri to Charleston
Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $109 (Southwest) |
Popular in | July |
Cheapest in | November |
Average price | $403 |
Good round-trip deal | $315 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Mon 6/1
1:27 pm-8:24 pm
1 stop5h 57m
Charleston
Sat 6/6
6:03 pm-11:59 pm
1 stop6h 56m
$267
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Mon 5/25
6:00 am-12:10 pm
1 stop5h 10m
Charleston
Mon 6/1
5:15 am-9:44 am
1 stop5h 29m
$267
SpringfieldCharleston
SGF - CHS
SGFCHS
Springfield-Branson
Wed 6/10
6:00 am-1:41 pm
1 stop6h 41m
Charleston
Wed 6/17
7:20 am-10:55 am
1 stop4h 35m
$277
SpringfieldCharleston
SGF - CHS
SGFCHS
Springfield-Branson
Sat 6/20
4:08 pm-10:06 pm
1 stop4h 58m
Charleston
Sat 6/27
5:03 pm-9:13 pm
1 stop5h 10m
$277
ColumbiaCharleston
COU - CHS
COUCHS
Columbia Regional
Wed 8/26
3:05 pm-9:48 pm
1 stop5h 43m
Charleston
Wed 9/2
3:25 pm-9:49 pm
1 stop7h 24m
$298
SpringfieldCharleston
SGF - CHS
SGFCHS
Springfield-Branson
Thu 6/11
6:58 pm-12:45 am
1 stop4h 47m
Charleston
Wed 6/17
6:24 pm-10:09 pm
1 stop4h 45m
$303
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 5/19
9:21 am-6:02 pm
1 stop7h 41m
Charleston
Wed 5/20
10:15 am-6:55 pm
2 stops9h 40m
$312
Quickest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 6/30
3:15 pm-6:15 pm
Nonstop2h 00m
Charleston
Thu 7/2
4:45 pm-5:50 pm
Nonstop2h 05m
$315
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 6/30
3:15 pm-6:15 pm
Nonstop2h 00m
Charleston
Sat 7/4
11:00 am-12:05 pm
Nonstop2h 05m
$315
ColumbiaCharleston
COU - CHS
COUCHS
Columbia Regional
Mon 6/8
3:05 pm-9:51 pm
1 stop5h 46m
Charleston
Wed 6/24
6:00 am-10:48 am
1 stop5h 48m
$318
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from Missouri to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
STL-CHS
COU-CHS
SGF-CHS
MCI-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Charleston
USMO-CHS
STL-CHS
COU-CHS
SGF-CHS
MCI-CHS
How far ahead should I book a flight from Missouri to Charleston?
Booking 46 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Missouri to Charleston?
Currently, June is the cheapest month in which you can book a flight from Missouri to Charleston (average of $109). Flying from Missouri to Charleston in January is currently the most expensive (average of $336). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to CHS?
Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Charleston as you normally would.
How much does it cost to fly round-trip from Missouri to Charleston?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Charleston flight routes
Complete your trip
Flights by cabin class
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Popular flights
Top destinations
Alternative routes for Missouri to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Charleston by cabin class
Find flights from Missouri to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Charleston flights
Browse other Missouri and Charleston flight options. Last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Charleston flights
Consider these flights traveling from Missouri to Charleston.
Top 4 airlines flying from Missouri to Charleston
Discover the top 4 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$206 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$237 | Average$401 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$243 | Average$392 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$516 | FlexibilityNo cancel fee | On-time69% |