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Cheap flights from Missouri (MO) to South Carolina (SC)

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How to find the cheapest flight from
Missouri to South Carolina

How far in advance should I book a flight from Missouri to South Carolina?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 16 days in advance, which can save you up to 21% on flights from Missouri to South Carolina compared to booking the week you need them. Waiting 16 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $234. For sooner than that we have options available in the next 3 days from $306.

What is the cheapest month to fly from Missouri to South Carolina?

Flights from Missouri to South Carolina lean towards being more expensive in December. Prices are generally better when you fly from Missouri to South Carolina in August, with the cheapest ticket starting at $124.

Cheap flights from Missouri to South Carolina in January, February 2021

The best prices found for Missouri to South Carolina flights for January, February
13 Feb - 17 Feb
$166pp
MCI
Kansas City
Spirit Airlines
   
2 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
   
2 STOPS
MCI
Kansas City
18 Feb - 21 Feb
$174pp
MCI
Kansas City
Multiple Airlines
   
2 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
   
2 STOPS
MCI
Kansas City
20 Feb - 27 Feb
$182pp
STL
Lambert-St Louis
American Airlines
 
1 STOP
CHS
Charleston AFB-Municipal
CHS
Charleston AFB-Municipal
American Airlines
 
1 STOP
STL
Lambert-St Louis

Missouri to South Carolina 2021 flight deals

Cheap flights to South Carolina from Missouri found for this year
21 Apr - 5 May
$132pp
MCI
Kansas City
Spirit Airlines
Non-Stop
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
Non-Stop
MCI
Kansas City
19 May - 22 May
$137pp
MCI
Kansas City
Spirit Airlines
Non-Stop
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
Non-Stop
MCI
Kansas City
19 May - 22 May
$158pp
MCI
Kansas City
Spirit Airlines
Non-Stop
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
Non-Stop
MCI
Kansas City

Non-stop flights to South Carolina from Missouri

Save time with Missouri to South Carolina direct flight deals
21 Apr - 5 May
$132pp
MCI
Kansas City
Spirit Airlines
Non-Stop
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
Non-Stop
MCI
Kansas City
19 May - 22 May
$137pp
MCI
Kansas City
Spirit Airlines
Non-Stop
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
Non-Stop
MCI
Kansas City
19 May - 22 May
$158pp
MCI
Kansas City
Spirit Airlines
Non-Stop
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
Non-Stop
MCI
Kansas City

Last minute flights from Missouri to South Carolina

Late deals on round-trip flights to South Carolina from Missouri, departing today and this week
29 Jan - 31 Jan
$267pp
MCI
Kansas City
Spirit Airlines
   
2 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
   
2 STOPS
MCI
Kansas City
29 Jan - 31 Jan
$270pp
MCI
Kansas City
Spirit Airlines
   
2 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Spirit Airlines
   
2 STOPS
MCI
Kansas City
31 Jan - 7 Feb
$297pp
STL
Lambert-St Louis
American Airlines
 
1 STOP
CAE
Columbia Metropolitan
CAE
Columbia Metropolitan
American Airlines
 
1 STOP
STL
Lambert-St Louis

One-way flights to South Carolina from Missouri

The cheapest one-way flights from Missouri to South Carolina
8:45 am - 9:07 am
Spirit Airlines
3 Stops
23h 22m
MCI - MYR
Spirit Airlines
$161
Gotogate
8:50 am - 9:00 am
Multiple Airlines
3 Stops
23h 10m
MCI - CHS
Multiple Airlines
$163
Kiwi.com
3:02 am - 12:26 pm
American Airlines
2 Stops
8h 24m
STL - GSP
American Airlines

Related info for your journey

Useful info, stats and facts about Missouri to South Carolina flights.

Flight FAQs

From Missouri to South Carolina

Are flight prices decreasing from Missouri to South Carolina due to COVID-19 (coronavirus)?

At this time, Cheapflights has noticed price decreases for many domestic flights due to COVID-19. Travel is not necessarily recommended at this time, and flights may be prone to cancellation: please check with local authorities in both Missouri and South Carolina for travel alerts, and be sure to review the airline's cancellation policy and travel advisories before booking. For more information, please view our post on what to know about COVID-19 (coronavirus) and travel.

What safety measures are being taken by airlines flying from Missouri to South Carolina to control the spread of COVID-19?

New policies can now be found on Delta to help keep travelers safe while flying. New policies for travelers booking flights from Missouri to South Carolina include masks being provided and required on board, daily cleaning and sanitization, use of HEPA filters, pre-flight testing for antibodies and symptoms, and socially distanced seating (for a limited time). Keep in mind that policies will vary by airline.

Which airlines flying from Missouri to South Carolina have flexible cancellations due to COVID-19?

Some of our airline partners flying from Missouri to South Carolina have new flexible policies in place due to COVID-19. American Airlines, Delta, and Spirit Airlines are some of the carriers where you may find flexible cancellation policies. You can use our site to filter for airlines like American Airlines with this kind of flexibility.

Can I find flights from Missouri to South Carolina for under $200 on Cheapflights?

Yes, there are multiple flights from Missouri to South Carolina for under $200. The cheapest flight booked recently is on Spirit Airlines for just $132, but on average you can expect to pay $183.

Are there nonstop flights from Missouri to South Carolina for under $200 on Cheapflights?

Cheapflights has at least 4 direct flights from Missouri to South Carolina under $200. A good price for a nonstop flight from Missouri to South Carolina is less than $199.

Are there last-minute flights available from Missouri to South Carolina for under $300?

There are currently 20+ open flights from Missouri to South Carolina within the next 7 days for less than $300.

How popular is this flight route?

Flights from Missouri to South Carolina have been viewed 28 times in the past calendar month.

What are the most popular airlines that fly from Missouri to South Carolina?

When booking a flight from Missouri to South Carolina, you may want to consider flying on Major Airline, American Airlines or Delta as they are the most popular for this route.

What are the most popular routes from Missouri to South Carolina?

Most travelers choose Kansas City - Charleston AFB-Municipal, Lambert-St Louis - Charleston AFB-Municipal or Kansas City - Myrtle Beach Metropolitan Area when deciding on the best route from Missouri to South Carolina.

What are the cheapest Flights from Missouri to South Carolina?

Looking at all options, your cheapest flight can be booked for $129. While the most popular route (Kansas City - Charleston AFB-Municipal) can be booked for $237 on average our data indicates $612 when flying from Missouri to South Carolina

How long is the flight from Missouri to South Carolina?

Spirit Airlines, Delta, and American Airlines can get you from Missouri to South Carolina in just under 2h 17m. Your travel time can differ by up to 1h 12m. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Missouri to South Carolina round-trip?

According to our current data, Spirit Airlines ($132), American Airlines ($182), and United Airlines ($185) offers the cheapest pricing from Missouri to South Carolina.

What are the cheapest airlines to fly from Missouri to South Carolina one-way?

To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $91. Spirit Airlines flights start at $107 while deals on Delta start at $173 one-way.

Destination points for flights from Missouri to South Carolina

Destination information for South Carolina

Things to know before you go. Useful info for your trip from Missouri to South Carolina
Flight duration
2h 25m

Airports servicing

Cape Girardeau (CGI)
Columbia (COU)
Kirksville (IRK)
Joplin (JLN)
Kansas City (MCI)

Airports servicing

Charleston (CHS)
Florence (FLO)
Greenville (GSP)
Hilton Head Island (HHH)
Myrtle Beach (MYR)

Top 6 airlines flying from Missouri to South Carolina

The chart below displays the airlines Cheapflights users traveling from Missouri to South Carolina choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.

Airline Cheapest Average Flexibility On-time COVID-19 safety
Spirit Airlines
$69 $198 No cancel fee 65%
Allegiant Air
$142 $207 No cancel fee 88%
Frontier
$133 $293 No cancel fee 62%
United Airlines
$92 $324 No cancel fee 69%
Delta
$133 $381 No cancel fee N/A
American Airlines
$136 $389 No cancel fee 71%
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