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Cheap flights from Missouri to South Carolina from $48

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
MCI — CHS
May 1 — May 81
From?
To?
Wed 5/1
Wed 5/8
1 adult, Economy
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When is the cheapest time to fly from Missouri to South Carolina (MO - SC)?

When flying from Missouri to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Cheap American Airlines flights from Missouri to South Carolina

Explore cheap flight options specifically provided by American Airlines for the route between Missouri and South Carolina. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
Take a peek at the cheapest American Airlines flights we've detected traveling from Missouri to South Carolina. Deals update often to give you more flight options matching your criteria
Wed 7/315:48 amMCI - CLT
1 stop8h 00mAmerican Airlines
Wed 7/314:15 pmCLT - MCI
Nonstop2h 23mAmerican Airlines
Deal found 4/24$185
Tue 5/215:04 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Tue 5/2810:30 pmCLT - STL
Nonstop1h 52mAmerican Airlines
Deal found 4/26$219
Wed 7/36:00 amSTL - CLT
1 stop7h 50mAmerican Airlines
Sat 7/67:26 amCLT - STL
Nonstop2h 04mAmerican Airlines
Deal found 4/25$232
Wed 5/227:30 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Sat 5/256:36 pmCLT - STL
Nonstop1h 54mAmerican Airlines
Deal found 4/26$234
Wed 7/36:00 amSTL - CLT
1 stop7h 50mAmerican Airlines
Sat 7/611:06 amCLT - STL
1 stop7h 15mAmerican Airlines
Deal found 4/25$241
Wed 7/37:00 amSTL - CLT
Nonstop1h 56mAmerican Airlines
Sat 7/67:26 amCLT - STL
Nonstop2h 04mAmerican Airlines
Deal found 4/25$243
Tue 10/2211:08 amSTL - CLT
Nonstop1h 52mAmerican Airlines
Sat 10/267:10 amCLT - STL
1 stop5h 40mAmerican Airlines
Deal found 4/25$244
Sat 5/255:04 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Tue 5/2810:30 pmCLT - STL
Nonstop1h 52mAmerican Airlines
Deal found 4/26$249
Thu 8/85:37 amSTL - CLT
Nonstop1h 53mAmerican Airlines
Sun 8/111:00 pmCLT - STL
Nonstop1h 56mAmerican Airlines
Deal found 4/25$258

Cheap Frontier flights from Missouri to South Carolina

Explore cheap flight options specifically provided by Frontier for the route between Missouri and South Carolina. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
Take a gander at the lowest prices we've found on Frontier flights from Missouri to South Carolina. If these deals don't fit your criteria, make sure to check back soon as new deals are always added.
Tue 5/147:16 pmSTL - CLT
1 stop12h 04mFrontier
Thu 5/1611:52 amCLT - STL
1 stop11h 14mFrontier
Deal found 4/25$123
Sat 5/188:04 pmSTL - CLT
1 stop13h 48mFrontier
Wed 5/293:20 pmCLT - STL
1 stop5h 50mFrontier
Deal found 4/25$132
Thu 5/97:16 pmSTL - CLT
1 stop12h 09mFrontier
Tue 5/148:35 pmCLT - STL
1 stop21h 20mFrontier
Deal found 4/25$133
Sat 5/48:04 pmSTL - CLT
1 stop15h 09mFrontier
Fri 5/1010:14 pmCLT - STL
1 stop18h 23mFrontier
Deal found 4/25$137
Mon 5/209:26 pmSTL - CLT
1 stop18h 33mFrontier
Fri 5/248:42 pmCLT - STL
1 stop21h 14mFrontier
Deal found 4/26$138
Sat 5/185:25 pmSTL - CLT
1 stop12h 30mFrontier
Sun 5/2611:52 amCLT - STL
1 stop11h 40mFrontier
Deal found 4/25$139
Wed 5/89:53 pmSTL - CLT
1 stop9h 32mFrontier
Sat 5/112:26 pmCLT - STL
1 stop17h 47mFrontier
Deal found 4/25$147
Wed 5/89:53 pmSTL - CLT
1 stop9h 32mFrontier
Sat 5/112:26 pmCLT - STL
1 stop17h 47mFrontier
Deal found 4/25$154
Tue 9/1010:32 pmSTL - CLT
1 stop19h 00mFrontier
Tue 9/177:12 pmCLT - STL
1 stop15h 25mFrontier
Deal found 4/25$156

Cheap Missouri to South Carolina flights in April & May 2024

Find cheap flight options from Missouri to South Carolina specifically for the months of April and May 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 3,068,117 searches. Prices were last updated on April 26, 2024.
Check out some of the best flight deals from Missouri to South Carolina in 2024. For more flight deals, be sure to check back very soon.
Wed 5/155:46 pmMCI - CLT
1 stop5h 13mMultiple Airlines
Wed 5/223:20 pmCLT - MCI
1 stop5h 32mMultiple Airlines
Deal found 4/26$105
Tue 5/75:00 amMCI - CLT
1 stop12h 32mSpirit Airlines
Sat 5/116:00 amCLT - MCI
2 stops15h 55mSpirit Airlines
Deal found 4/25$115
Tue 5/147:16 pmSTL - CLT
1 stop12h 04mFrontier
Thu 5/1611:52 amCLT - STL
1 stop11h 14mFrontier
Deal found 4/25$123
Tue 5/75:00 amMCI - CLT
1 stop12h 32mSpirit Airlines
Sat 5/116:30 amCLT - MCI
1 stop16h 25mSpirit Airlines
Deal found 4/25$126
Tue 5/75:00 amMCI - CLT
1 stop16h 55mSpirit Airlines
Sat 5/116:00 amCLT - MCI
2 stops15h 55mSpirit Airlines
Deal found 4/25$128
Sat 5/188:04 pmSTL - CLT
1 stop13h 48mFrontier
Wed 5/293:20 pmCLT - STL
1 stop5h 50mFrontier
Deal found 4/25$132
Thu 5/97:16 pmSTL - CLT
1 stop12h 09mFrontier
Tue 5/148:35 pmCLT - STL
1 stop21h 20mFrontier
Deal found 4/25$133
Wed 5/155:46 pmMCI - CLT
1 stop5h 13mSpirit Airlines
Wed 5/224:53 pmCLT - MCI
2 stops32h 48mSpirit Airlines
Deal found 4/26$134
Tue 5/75:00 amMCI - CLT
2 stops18h 08mSpirit Airlines
Sat 5/116:00 amCLT - MCI
2 stops15h 55mSpirit Airlines
Deal found 4/25$135

Missouri to South Carolina 2024 flight deals

Discover exclusive flight deals for travel between Missouri and South Carolina in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
Check out some of the best flight deals from Missouri to South Carolina in 2024. For more flight deals, be sure to check back very soon.
Wed 5/155:46 pmMCI - CLT
1 stop5h 13mMultiple Airlines
Wed 5/223:20 pmCLT - MCI
1 stop5h 32mMultiple Airlines
Deal found 4/26$105
Tue 5/75:00 amMCI - CLT
1 stop12h 32mSpirit Airlines
Sat 5/116:00 amCLT - MCI
2 stops15h 55mSpirit Airlines
Deal found 4/25$115
Tue 5/147:16 pmSTL - CLT
1 stop12h 04mFrontier
Thu 5/1611:52 amCLT - STL
1 stop11h 14mFrontier
Deal found 4/25$123
Tue 5/75:00 amMCI - CLT
1 stop12h 32mSpirit Airlines
Sat 5/116:30 amCLT - MCI
1 stop16h 25mSpirit Airlines
Deal found 4/25$126
Tue 5/75:00 amMCI - CLT
1 stop16h 55mSpirit Airlines
Sat 5/116:00 amCLT - MCI
2 stops15h 55mSpirit Airlines
Deal found 4/25$128
Sat 5/188:04 pmSTL - CLT
1 stop13h 48mFrontier
Wed 5/293:20 pmCLT - STL
1 stop5h 50mFrontier
Deal found 4/25$132
Thu 5/97:16 pmSTL - CLT
1 stop12h 09mFrontier
Tue 5/148:35 pmCLT - STL
1 stop21h 20mFrontier
Deal found 4/25$133
Wed 5/155:46 pmMCI - CLT
1 stop5h 13mSpirit Airlines
Wed 5/224:53 pmCLT - MCI
2 stops32h 48mSpirit Airlines
Deal found 4/26$134
Tue 5/75:00 amMCI - CLT
2 stops18h 08mSpirit Airlines
Sat 5/116:00 amCLT - MCI
2 stops15h 55mSpirit Airlines
Deal found 4/25$135

Non-stop flights to South Carolina from Missouri

Discover non-stop flight options from Missouri to South Carolina. Find direct flights with no layovers, providing a convenient travel experience. Explore non-stop flight options based on user searches, and compare prices and availability for your desired travel dates. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
To help reduce your travel time, choose from one of these non-stop flights from Missouri to South Carolina. Users can also choose from other Missouri to South Carolina flights by using the search form above.
Tue 5/215:04 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Tue 5/2810:30 pmCLT - STL
Nonstop1h 52mAmerican Airlines
Deal found 4/26$219
Tue 10/227:37 amSTL - CLT
Nonstop1h 53mAmerican Airlines
Sat 10/2610:20 pmCLT - STL
Nonstop2h 00mAmerican Airlines
Deal found 4/25$234
Wed 7/37:00 amSTL - CLT
Nonstop1h 56mAmerican Airlines
Sat 7/67:26 amCLT - STL
Nonstop2h 04mAmerican Airlines
Deal found 4/25$243
Sat 5/255:04 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Tue 5/2810:30 pmCLT - STL
Nonstop1h 52mAmerican Airlines
Deal found 4/26$249
Thu 8/85:37 amSTL - CLT
Nonstop1h 53mAmerican Airlines
Sun 8/111:00 pmCLT - STL
Nonstop1h 56mAmerican Airlines
Deal found 4/25$258
Sun 6/95:15 amSTL - CLT
Nonstop1h 56mAmerican Airlines
Fri 6/147:31 amCLT - STL
Nonstop2h 02mAmerican Airlines
Deal found 4/25$267
Fri 5/314:20 pmSTL - CLT
Nonstop1h 54mAmerican Airlines
Sun 6/212:15 pmCLT - STL
Nonstop1h 55mAmerican Airlines
Deal found 4/25$270
Sun 5/264:20 pmSTL - CLT
Nonstop1h 54mAmerican Airlines
Sun 6/212:15 pmCLT - STL
Nonstop1h 55mAmerican Airlines
Deal found 4/25$281
Tue 5/145:04 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Tue 5/2110:30 pmCLT - STL
Nonstop1h 52mAmerican Airlines
Deal found 4/25$291

Missouri to South Carolina flights leaving soon

Find last-minute flight options from Missouri to South Carolina for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
Consider one of these great deals we found on last-minute flights from Missouri to South Carolina. To prevent any unwanted surprises, users should verify their flight info before booking.
Sat 5/48:04 pmSTL - CLT
1 stop15h 09mFrontier
Fri 5/1010:14 pmCLT - STL
1 stop18h 23mFrontier
Deal found 4/25$137
Sat 5/48:04 pmSTL - CLT
1 stop15h 09mFrontier
Tue 5/78:49 pmCLT - STL
1 stop25h 04mFrontier
Deal found 4/25$157
Thu 5/211:38 amSTL - CLT
1 stop23h 45mFrontier
Tue 5/78:49 pmCLT - STL
1 stop25h 04mFrontier
Deal found 4/25$166
Thu 5/211:38 amSTL - CLT
1 stop23h 45mFrontier
Sun 5/58:50 pmCLT - STL
1 stop24h 21mFrontier
Deal found 4/25$175
Thu 5/27:07 pmMCI - CLT
1 stop16h 16mFrontier
Thu 5/99:00 amCLT - MCI
1 stop25h 14mFrontier
Deal found 4/25$176
Wed 5/19:53 pmSTL - CLT
1 stop9h 32mFrontier
Mon 5/62:43 pmCLT - STL
1 stop6h 28mFrontier
Deal found 4/25$178
Fri 5/37:16 pmSTL - CLT
1 stop11h 49mFrontier
Sun 5/128:50 pmCLT - STL
1 stop24h 21mFrontier
Deal found 4/25$196
Mon 5/65:02 pmSTL - CHS
1 stop22h 09mSpirit Airlines
Thu 5/912:52 pmCHS - STL
1 stop5h 37mSpirit Airlines
Deal found 4/25$204
Wed 5/19:53 pmSTL - CLT
1 stop9h 32mFrontier
Tue 5/79:05 amCLT - STL
1 stop7h 45mFrontier
Deal found 4/25$217

One-way flights to South Carolina from Missouri

Search for one-way flight options from Missouri to South Carolina. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
Users in need of a one-way flight from Missouri to South Carolina can choose from these deals. Users can also find round-trip Missouri to South Carolina flights by using the search form above.
Wed 5/295:46 pmMCI - CLT
1 stop5h 13mSpirit Airlines
Deal found 4/24$48
Tue 5/2810:34 amSTL - CLT
1 stop8h 10mSpirit Airlines
Deal found 4/26$55
Tue 5/2110:34 amSTL - MYR
1 stop9h 10mSpirit Airlines
Deal found 4/25$56
Mon 5/139:11 pmSTL - CLT
1 stop21h 24mFrontier
Deal found 4/25$60
Tue 5/2810:34 amSTL - CLT
2 stops23h 24mSpirit Airlines
Deal found 4/26$65
Tue 5/75:00 amMCI - CLT
1 stop16h 55mSpirit Airlines
Deal found 4/26$67
Sat 5/119:40 pmMCI - CLT
1 stop10h 40mSpirit Airlines
Deal found 4/26$68
Tue 5/2110:34 amSTL - MYR
2 stops22h 51mSpirit Airlines
Deal found 4/25$77
Sat 5/258:57 amSTL - CLT
1 stop7h 57mFrontier
Deal found 4/25$80

Find flights from Missouri to South Carolina within your budget

Customize your flight search to find flights from Missouri to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$115 - $253

Route

Depart

Return

Price

Kansas CityCharlotte Douglas

MCI - CLT

MCICLT

Kansas City

Tue 5/7

1 stop12h 32m

Charlotte Douglas

Sat 5/11

2 stops15h 55m

$115

Lambert-St LouisCharlotte Douglas

STL - CLT

STLCLT

Lambert-St Louis

Tue 5/14

1 stop12h 04m

Charlotte Douglas

Thu 5/16

1 stop11h 14m

$123

Kansas CityCharlotte Douglas

MCI - CLT

MCICLT

Kansas City

Tue 5/7

1 stop12h 32m

Charlotte Douglas

Sat 5/11

1 stop16h 25m

$126

Lambert-St LouisCharlotte Douglas

STL - CLT

STLCLT

Lambert-St Louis

Sat 5/18

1 stop13h 48m

Charlotte Douglas

Wed 5/29

1 stop5h 50m

$132

Kansas CityCharlotte Douglas

MCI - CLT

MCICLT

Kansas City

Wed 5/22

1 stop11h 16m

Charlotte Douglas

Tue 6/4

1 stop14h 09m

$149

Kansas CityCharlotte Douglas

MCI - CLT

MCICLT

Kansas City

Wed 7/31

1 stop8h 00m

Charlotte Douglas

Wed 7/31

Nonstop2h 23m

$185

Kansas CityColumbia Metropolitan

MCI - CAE

MCICAE

Kansas City

Sat 9/14

1 stop6h 41m

Columbia Metropolitan

Tue 9/17

1 stop4h 30m

$216

Lambert-St LouisMyrtle Beach Intl

STL - MYR

STLMYR

Lambert-St Louis

Sun 5/26

1 stop17h 06m

Myrtle Beach Intl

Thu 5/30

1 stop24h 33m

$235

Kansas CityColumbia Metropolitan

MCI - CAE

MCICAE

Kansas City

Thu 5/16

1 stop5h 29m

Columbia Metropolitan

Sun 5/19

1 stop5h 18m

$253

Flights are sorted by cheapest first

Deals found on 4/25

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 26, 2024.
Read reviews from past customers who have flown American Airlines, Frontier and Spirit Airlines from Missouri to South Carolina. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.2
Very good
6,173 reviews
Check prices

Entertainment

7.8

Overall

8.2

Food

7.4

Boarding

8.3

Comfort

8.1

Crew

8.7

Reviews

1 / 10

I was traveling with a companion that utilizes a scooter to get around. We have flown together many times and used other airlines. Southwest by far is the most accommodating airline in the fleet your staff Makes the accessibility easy and convenient for for this type of travel. We would personally like to think the flight teams of our two flights for being very accommodating and helpful throughout our trip.

Southwest
8.2
Very good
6,173 reviews
Southwest
8.2
Very good
6,173 reviews
Check prices

Entertainment

7.8

Overall

8.2

Food

7.4

Boarding

8.3

Comfort

8.1

Crew

8.7

Reviews

1 / 10

I was traveling with a companion that utilizes a scooter to get around. We have flown together many times and used other airlines. Southwest by far is the most accommodating airline in the fleet your staff Makes the accessibility easy and convenient for for this type of travel. We would personally like to think the flight teams of our two flights for being very accommodating and helpful throughout our trip.

Alaska Airlines
8.1
Very good
9,115 reviews
Southwest
8.2
Very good
6,173 reviews
Check prices

Entertainment

7.8

Overall

8.2

Food

7.4

Boarding

8.3

Comfort

8.1

Crew

8.7

Reviews

1 / 10

I was traveling with a companion that utilizes a scooter to get around. We have flown together many times and used other airlines. Southwest by far is the most accommodating airline in the fleet your staff Makes the accessibility easy and convenient for for this type of travel. We would personally like to think the flight teams of our two flights for being very accommodating and helpful throughout our trip.

Delta
8.1
Very good
10,966 reviews
Southwest
8.2
Very good
6,173 reviews
Check prices

Entertainment

7.8

Overall

8.2

Food

7.4

Boarding

8.3

Comfort

8.1

Crew

8.7

Reviews

1 / 10

I was traveling with a companion that utilizes a scooter to get around. We have flown together many times and used other airlines. Southwest by far is the most accommodating airline in the fleet your staff Makes the accessibility easy and convenient for for this type of travel. We would personally like to think the flight teams of our two flights for being very accommodating and helpful throughout our trip.

United Airlines
7.4
Good
11,228 reviews
Southwest
8.2
Very good
6,173 reviews
Check prices

Entertainment

7.8

Overall

8.2

Food

7.4

Boarding

8.3

Comfort

8.1

Crew

8.7

Reviews

1 / 10

I was traveling with a companion that utilizes a scooter to get around. We have flown together many times and used other airlines. Southwest by far is the most accommodating airline in the fleet your staff Makes the accessibility easy and convenient for for this type of travel. We would personally like to think the flight teams of our two flights for being very accommodating and helpful throughout our trip.

American Airlines
7.3
Good
14,889 reviews
Southwest
8.2
Very good
6,173 reviews
Check prices

Entertainment

7.8

Overall

8.2

Food

7.4

Boarding

8.3

Comfort

8.1

Crew

8.7

Reviews

1 / 10

I was traveling with a companion that utilizes a scooter to get around. We have flown together many times and used other airlines. Southwest by far is the most accommodating airline in the fleet your staff Makes the accessibility easy and convenient for for this type of travel. We would personally like to think the flight teams of our two flights for being very accommodating and helpful throughout our trip.

Related info for your journey

Find useful and relevant information for your journey from Missouri to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find flights from Missouri to South Carolina for under $200 on Cheapflights?

    Yes, there are multiple flights from Missouri to South Carolina for under $200. The cheapest flight booked recently is on Spirit Airlines for just $115, but on average you can expect to pay $141.

  • Are there nonstop flights from Missouri to South Carolina for under $300 on Cheapflights?

    Cheapflights has at least 20 direct flights from Missouri to South Carolina under $300. A good price for a nonstop flight from Missouri to South Carolina is less than $282.

  • Are there last-minute flights available from Missouri to South Carolina for under $200?

    There are currently 20+ open flights from Missouri to South Carolina within the next 7 days for less than $200.

  • What does MCI to CHS mean?

    Great question - MCI to CHS just means Kansas City Airport to Charleston Airport. Now you’ll know what these unique codes when you look for flights! Myrtle Beach Intl Airport (MYR), Greenville Airport (GSP), Columbia Metropolitan Airport (CAE), Hilton Head Island Airport (HHH), Florence Airport (FLO) are some additional IATA codes for airports related to your trip.

  • Can I find deals for flights from Missouri to South Carolina that include extra baggage allowance?

    The amount of baggage you can bring on your Missouri to South Carolina flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Missouri to South Carolina with specific airlines?

    Yes, Cheapflights allows you to browse and filter Missouri to South Carolina flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Missouri to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missouri to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to South Carolina.

  • Can I find deals for business class flights from Missouri to South Carolina?

    Yes. Cheapflights offers flight deals from Missouri to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Missouri to South Carolina that allow pets onboard?

    Many airlines flying from Missouri to South Carolina offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Missouri to South Carolina?

    Yes, you can often find last-minute deals on Missouri to South Carolina flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Missouri to South Carolina flight deals updated?

    The Missouri to South Carolina flight deals you see on this page were last updated on 4/26.

See more FAQs

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Top 6 airlines flying from Missouri to South Carolina

Discover the top 6 airlines that operate flights from Missouri to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 3,068,117 searches. Data last updated April 26, 2024.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$148Average$268FlexibilityNo cancel feeOn-time65%
Search Spirit Airlines flights
JetBlueCheapest$184Average$278FlexibilityNo cancel feeOn-time62%
Search JetBlue flights
American AirlinesCheapest$209Average$447FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest$227Average$418FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
United AirlinesCheapest$259Average$380FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Alaska AirlinesCheapest$445Average$543FlexibilityNo cancel feeOn-time75%
Search Alaska Airlines flights
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Missouri to South Dakota flights

Search flights from Missouri to South Carolina by cabin class

Find flights from Missouri to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
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How does Cheapflights help users find flights from Missouri to South Carolina?

When you search for this flight from Missouri to South Carolina, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Missouri to South Carolina?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Missouri to South Carolina for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Missouri to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Missouri to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Missouri to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Missouri to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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