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Missouri

$72+ Cheap flights from South Carolina to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from South Carolina to Missouri

Keep the following information in mind while searching for South Carolina to Missouri flight deals. Data was last updated July 3, 2025.

Round-trip from

$135
(Mytrip)

One-way from

$72
(Priceline)

Popular in

June

Cheapest in

February

Average price

$360

Good round-trip deal

$287 or less

Good one-way deal

$238 or less
From South Carolina to Missouri
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One-way flight from South Carolina to Missouri
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Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from South Carolina to Missouri.
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Price to beat on a one-way flight from South Carolina to Missouri.
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Find flight deals from South Carolina to Missouri

Cheapest flights from South Carolina to Missouri
Explore the most affordable flight options available from South Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/167:03 pmCLT - STL
1 stop5h 44mFrontier
Sat 8/237:54 pmSTL - CLT
1 stop19h 43mFrontier
Deal found 7/2$135
This Priceline deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/157:03 pmCLT - STL
1 stop5h 44mMultiple Airlines
Thu 7/1710:47 amSTL - CLT
1 stop5h 37mMultiple Airlines
Deal found 7/2$177
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/26:00 amCLT - STL
1 stop9h 39mSpirit Airlines
Mon 8/1110:47 amSTL - CLT
1 stop5h 30mSpirit Airlines
Deal found 6/30$179
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:50 pmCLT - STL
Nonstop2h 00mSouthwest
Mon 8/182:45 pmSTL - CLT
Nonstop1h 50mSouthwest
Deal found 7/3$197
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:23 pmCHS - STL
1 stop6h 30mDelta
Thu 8/146:49 pmSTL - CHS
1 stop4h 02mDelta
Deal found 7/3$207
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1610:42 amCAE - STL
1 stop6h 33mAmerican Airlines
Sat 9/206:27 amSTL - CAE
1 stop5h 46mAmerican Airlines
Deal found 7/3$211
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:45 pmCHS - STL
1 stop4h 20mSouthwest
Mon 8/257:50 amSTL - CHS
Nonstop1h 55mSouthwest
Deal found 7/1$221
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:05 amCLT - STL
1 stop6h 21mDelta
Sat 9/66:00 amSTL - CLT
1 stop5h 59mDelta
Deal found 7/3$227
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:36 pmCLT - STL
1 stop7h 56mAmerican Airlines
Sat 9/62:11 pmSTL - CLT
Nonstop2h 00mAmerican Airlines
Deal found 7/3$230
This FlightHub deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/26:20 amCLT - MCI
1 stop9h 57mSpirit Airlines
Fri 8/84:23 pmMCI - CLT
1 stop27h 10mSpirit Airlines
Deal found 7/2$233
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:50 pmCLT - MCI
1 stop3h 45mSouthwest
Mon 9/110:35 amMCI - CLT
1 stop4h 55mSouthwest
Deal found 7/3$236
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:45 pmGSP - MCI
1 stop5h 10mSouthwest
Mon 9/17:15 amMCI - GSP
1 stop5h 00mSouthwest
Deal found 7/1$237

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from South Carolina to Missouri that are best for you.

Fly from

South Carolina

Fly to

Missouri

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/16

7:03 pm-11:47 pm

1 stop5h 44m

Lambert-St Louis

Sat 8/23

7:54 pm-4:37 pm

1 stop19h 43m

$135

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 7/15

7:03 pm-11:47 pm

1 stop5h 44m

Lambert-St Louis

Thu 7/17

10:47 am-5:24 pm

1 stop5h 37m

$177

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/2

6:00 am-2:39 pm

1 stop9h 39m

Lambert-St Louis

Mon 8/11

10:47 am-5:17 pm

1 stop5h 30m

$179

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 8/14

7:50 pm-8:50 pm

Nonstop2h 00m

Lambert-St Louis

Mon 8/18

2:45 pm-5:35 pm

Nonstop1h 50m

$197

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 8/7

6:23 pm-11:53 pm

1 stop6h 30m

Lambert-St Louis

Thu 8/14

6:49 pm-11:51 pm

1 stop4h 02m

$207

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Tue 9/16

10:42 am-4:15 pm

1 stop6h 33m

Lambert-St Louis

Sat 9/20

6:27 am-1:13 pm

1 stop5h 46m

$211

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 8/20

6:45 pm-10:05 pm

1 stop4h 20m

Lambert-St Louis

Mon 8/25

7:50 am-10:45 am

Nonstop1h 55m

$221

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 9/4

7:05 am-12:26 pm

1 stop6h 21m

Lambert-St Louis

Sat 9/6

6:00 am-12:59 pm

1 stop5h 59m

$227

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 9/4

1:36 pm-8:32 pm

1 stop7h 56m

Lambert-St Louis

Sat 9/6

2:11 pm-5:11 pm

Nonstop2h 00m

$230

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 8/2

6:20 am-3:17 pm

1 stop9h 57m

Kansas City

Fri 8/8

4:23 pm-8:33 pm

1 stop27h 10m

$233

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missouri

What is the cheapest month to book a flight from South Carolina to Missouri?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MO?

Find hourly flight availability from South Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 3, 2025.
Read through reviews of airlines operating flights from South Carolina to Missouri, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Entertainment

7.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Entertainment

7.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Entertainment

7.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Entertainment

7.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Entertainment

7.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Spirit Airlines
6.3
Okay
8,086 reviews
Southwest
8.0
Very good
4,266 reviews

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Entertainment

7.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Missouri flight route?

    The South Carolina to Missouri flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Missouri one-way?

    One-way options have recently been found by users for as low as $72 on Frontier. Other airlines that offer cheap prices include Spirit Airlines from $98 and Southwest from $99 one-way.

  • Can I find deals for flights from South Carolina to Missouri that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missouri.

  • Can I find deals for business class flights from South Carolina to Missouri?

    Yes. Cheapflights offers flight deals from South Carolina to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Missouri?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Missouri

Discover the top 5 airlines that operate flights from South Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$139Average$355FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$158Average$389FlexibilityNo cancel feeOn-time71%
Spirit AirlinesCheapest$199Average$243FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$388FlexibilityNo cancel feeOn-time63%

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