$112+ Cheap flights from South Carolina to Mississippi
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — JAN
Oct 22 — Oct 291
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to MississippiExplore the most affordable flight options available from South Carolina to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from South Carolina to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:13 pm -
1 stop5h 52m
Sun 10/257:45 pm -
1 stop12h 03m
Deal found 9/18![Breeze Airways logo]()
$171
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:05 am -
2 stops6h 25m
Tue 12/81:10 pm -
1 stop4h 00m
Deal found 9/20![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:44 pm -
1 stop6h 06m
Sun 12/133:48 pm -
1 stop5h 34m
Deal found 9/18![Delta logo]()
$318
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:14 pm -
1 stop4h 55m
Sun 10/253:33 pm -
1 stop6h 18m
Deal found 9/19![Delta logo]()
$336
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:59 pm -
1 stop3h 41m
Sun 10/255:35 am -
1 stop4h 08m
Deal found 9/18![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:35 pm -
1 stop4h 24m
Tue 11/171:48 pm -
1 stop6h 09m
Deal found 9/20![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:33 pm -
1 stop4h 26m
Tue 10/205:39 pm -
1 stop4h 17m
Deal found 9/22![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
2 stops6h 25m
Sun 12/1311:45 am -
1 stop10h 10m
Deal found 9/18![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:12 pm -
1 stop4h 43m
Sun 10/256:45 pm -
1 stop4h 02m
Deal found 9/22![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop4h 55m
Sun 10/255:35 am -
1 stop3h 35m
Deal found 9/21![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop3h 17m
Sat 10/3110:03 am -
1 stop3h 51m
Deal found 9/17![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:27 pm -
1 stop7h 14m
Tue 12/812:21 pm -
1 stop5h 34m
Deal found 9/20![American Airlines logo]()
$368
Best flights from South Carolina to MississippiDiscover carefully curated flight deals from South Carolina to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from South Carolina to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:05 am -
2 stops6h 25m
Tue 12/81:10 pm -
1 stop4h 00m
Deal found 9/20![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:44 pm -
1 stop6h 06m
Sun 12/133:48 pm -
1 stop5h 34m
Deal found 9/18![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:35 pm -
1 stop4h 24m
Tue 11/171:48 pm -
1 stop6h 09m
Deal found 9/20![American Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
2 stops43h 09m
Sun 10/117:45 pm -
1 stop12h 00m
Deal found 9/22![Breeze Airways logo]()
$466
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am -
1 stop7h 48m
Mon 11/91:54 pm -
1 stop7h 05m
Deal found 9/20![United Airlines logo]()
$512
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:14 pm -
1 stop4h 55m
Sun 10/253:33 pm -
1 stop6h 18m
Deal found 9/19![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
2 stops6h 25m
Sun 12/1311:45 am -
1 stop10h 10m
Deal found 9/18![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:47 pm -
1 stop6h 15m
Sun 11/156:34 pm -
1 stop4h 21m
Deal found 9/21![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:35 am -
1 stop5h 54m
Sat 11/148:00 am -
1 stop4h 25m
Deal found 9/22![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:12 pm -
1 stop4h 43m
Sun 10/256:45 pm -
1 stop4h 02m
Deal found 9/22![American Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:55 pm -
1 stop4h 55m
Sun 10/255:45 am -
2 stops12h 40m
Deal found 9/22![Southwest logo]()
$370
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:59 pm -
1 stop3h 41m
Sun 10/255:35 am -
1 stop4h 08m
Deal found 9/18![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:59 pm -
1 stop4h 42m
Tue 12/12:51 pm -
1 stop3h 48m
Deal found 9/19![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop4h 55m
Sun 10/255:35 am -
1 stop3h 35m
Deal found 9/21![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:35 pm -
1 stop6h 15m
Sun 10/255:45 am -
2 stops10h 50m
Deal found 9/21![Southwest logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:12 am -
1 stop23h 39m
Sun 10/187:45 pm -
1 stop19h 02m
Deal found 9/18![Breeze Airways logo]()
$491
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:33 pm -
1 stop3h 59m
Wed 10/76:42 pm -
1 stop4h 14m
Deal found 9/18![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop3h 17m
Sat 10/3110:03 am -
1 stop3h 51m
Deal found 9/17![Delta logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:00 am -
1 stop7h 25m
Sat 10/32:00 pm -
1 stop7h 21m
Deal found 9/20![United Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:28 pm -
1 stop6h 13m
Wed 12/96:45 am -
1 stop6h 05m
Deal found 9/21![American Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:25 am -
2 stops16h 30m
Sun 10/255:45 am -
2 stops14h 50m
Deal found 9/19![Southwest logo]()
$445
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:20 am -
1 stop6h 09m
Tue 11/245:06 pm -
1 stop5h 53m
Deal found 9/22![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:30 pm -
1 stop4h 25m
Tue 10/277:45 am -
1 stop6h 13m
Deal found 9/18![American Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:49 am -
1 stop7h 29m
Sat 10/317:00 am -
1 stop7h 14m
Deal found 9/18![United Airlines logo]()
$618
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 am -
1 stop6h 50m
Sun 10/1812:55 pm -
1 stop8h 10m
Deal found 9/18![Southwest logo]()
$500
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:00 pm -
2 stops21h 18m
Sat 10/172:00 pm -
1 stop7h 21m
Deal found 9/21![United Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:34 pm -
1 stop5h 18m
Sun 11/226:26 am -
1 stop4h 26m
Deal found 9/22![Delta logo]()
$450
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:25 am -
1 stop8h 35m
Sat 10/1011:25 am -
1 stop5h 50m
Deal found 9/21![Southwest logo]()
$502
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:50 am -
2 stops13h 10m
Sun 10/1112:55 pm -
2 stops8h 10m
Deal found 9/22![Southwest logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:01 pm -
1 stop4h 58m
Sun 10/116:11 am -
1 stop3h 50m
Deal found 9/17![American Airlines logo]()
$516
Last-minute flights from South Carolina to MississippiDiscover last-minute flight deals from South Carolina to Mississippi. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Mississippi. Data last updated September 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:33 pm -
1 stop3h 59m
Wed 10/76:42 pm -
1 stop4h 14m
Deal found 9/18![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:08 pm -
1 stop4h 51m
Tue 10/205:39 pm -
1 stop4h 19m
Deal found 9/20![American Airlines logo]()
$415
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:33 pm -
1 stop4h 26m
Tue 10/205:39 pm -
1 stop4h 17m
Deal found 9/22![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:12 pm -
1 stop4h 47m
Sat 10/246:42 pm -
1 stop4h 05m
Deal found 9/19![American Airlines logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:13 pm -
1 stop5h 52m
Sun 10/257:45 pm -
1 stop12h 03m
Deal found 9/18![Breeze Airways logo]()
$171
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:59 pm -
1 stop3h 41m
Sun 10/255:35 am -
1 stop4h 08m
Deal found 9/18![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:12 pm -
1 stop4h 43m
Sun 10/256:45 pm -
1 stop4h 02m
Deal found 9/22![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop4h 55m
Sun 10/255:35 am -
1 stop3h 35m
Deal found 9/21![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:55 pm -
1 stop4h 55m
Sun 10/255:45 am -
2 stops12h 40m
Deal found 9/22![Southwest logo]()
$370
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:35 pm -
1 stop6h 15m
Sun 10/255:45 am -
2 stops10h 50m
Deal found 9/21![Southwest logo]()
$405
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:14 pm -
1 stop4h 55m
Sun 10/253:33 pm -
1 stop6h 18m
Deal found 9/19![Delta logo]()
$336
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop3h 17m
Sat 10/3110:03 am -
1 stop3h 51m
Deal found 9/17![Delta logo]()
$353
One-way flights from South Carolina to MississippiSearch for one-way flight options from South Carolina to Mississippi. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from South Carolina to Mississippi. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:39 pm -
1 stop12h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Breeze Airways logo]()
$112
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:40 am -
1 stop5h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
3 stops38h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 pm -
3 stops50h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:42 pm -
1 stop28h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Breeze Airways logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:46 pm -
1 stop5h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Breeze Airways logo]()
$217
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:37 pm -
1 stop7h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$222
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:33 pm -
1 stop4h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$245
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:41 pm -
1 stop4h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:30 am -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$256
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:00 pm -
1 stop3h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:00 am -
2 stops7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Southwest logo]()
$293
Find flight deals from South Carolina to Mississippi
Keep the following information in mind while searching for South Carolina to Mississippi flight deals. Data was last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $171 (Kiwi.com) |
One-way from | $112 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from South Carolina to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGulfport
CHS Charleston - GPT Gulfport Biloxi Regional
CHSGPT
Charleston
Thu 10/29
9:39 pm-8:51 am
1 stop12h 12m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$112
GreenvilleJackson
GSP Greenville - JAN Jackson-Evers Intl
GSPJAN
Greenville
Sat 10/10
5:40 am-9:54 am
1 stop5h 14m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
CharlestonGulfport
CHS Charleston - GPT Gulfport Biloxi Regional
CHSGPT
Charleston
Wed 10/28
6:00 am-7:05 pm
3 stops38h 05m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
CharlestonGulfport
CHS Charleston - GPT Gulfport Biloxi Regional
CHSGPT
Charleston
Tue 10/27
6:00 pm-7:05 pm
3 stops50h 05m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$186
CharlestonGulfport
CHS Charleston - GPT Gulfport Biloxi Regional
CHSGPT
Charleston
Wed 10/28
3:42 pm-7:05 pm
1 stop28h 23m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$201
Myrtle BeachGulfport
MYR Myrtle Beach Intl - GPT Gulfport Biloxi Regional
MYRGPT
Myrtle Beach Intl
Sun 10/4
2:46 pm-7:05 pm
1 stop5h 19m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$217
GreenvilleJackson
GSP Greenville - JAN Jackson-Evers Intl
GSPJAN
Greenville
Wed 10/7
8:33 pm-11:55 pm
1 stop4h 22m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$245
CharlestonJackson
CHS Charleston - JAN Jackson-Evers Intl
CHSJAN
Charleston
Sun 10/4
8:41 pm-11:50 pm
1 stop4h 09m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$249
GreenvilleJackson
GSP Greenville - JAN Jackson-Evers Intl
GSPJAN
Greenville
Wed 10/7
8:30 am-6:00 pm
2 stops10h 30m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$256
GreenvilleJackson
GSP Greenville - JAN Jackson-Evers Intl
GSPJAN
Greenville
Sat 10/10
8:00 am-2:45 pm
2 stops7h 45m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$293
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from South Carolina with our price prediction graph.
CHS-GPT
GSP-JAN
MYR-GPT
CHS-JAN
CAE-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Mississippi
USSC-USMS
CHS-GPT
GSP-JAN
MYR-GPT
CHS-JAN
What is the cheapest month to book a flight from South Carolina to Mississippi?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Mississippi (average of $318). Flying from South Carolina to Mississippi in April is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 22, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from South Carolina to Mississippi to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Mississippi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Mississippi by cabin class
Find flights from South Carolina to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Mississippi flights
Browse other South Carolina and Mississippi flight options. Last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mississippi
Find the right flight back to South Carolina after your stay in Mississippi
South Carolina to Mississippi flights
Consider these flights traveling from South Carolina to Mississippi.
Top 2 airlines flying from South Carolina to Mississippi
Discover the top 2 airlines that operate flights from South Carolina to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$437 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$323 | Average$496 | FlexibilityNo cancel fee | On-time71% |