$81+ Cheap flights from Mississippi to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Jul 20 — Jul 271
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to South Carolina
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Cheapest flights from Mississippi to South CarolinaExplore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Wed 7/296:41 pm
CLT
- MEM
1 stop14h 18m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Sat 8/86:41 pm
CLT
- MEM
1 stop14h 03m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:40 pm
MEM
- GSP
1 stop16h 45m
Allegiant Air
Sun 7/193:51 pm
GSP
- MEM
1 stop4h 59m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$220
This Booking.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:59 pm
MEM
- CLT
1 stop21h 20m
Frontier
Wed 9/98:11 pm
CLT
- MEM
1 stop23h 04m
Frontier
Deal found 6/17![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:04 pm
MEM
- SAV
1 stop23h 51m
Multiple Airlines
Sat 8/2212:19 pm
SAV
- MEM
1 stop27h 48m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:49 am
MEM
- CLT
1 stop11h 18m
Multiple Airlines
Sat 8/86:41 pm
CLT
- MEM
1 stop14h 03m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:49 am
MEM
- CLT
1 stop11h 18m
Multiple Airlines
Thu 8/66:41 pm
CLT
- MEM
1 stop22h 33m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:49 am
MEM
- GSP
1 stop22h 08m
Multiple Airlines
Fri 7/108:13 pm
GSP
- MEM
2 stops12h 46m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:49 am
MEM
- GSP
1 stop22h 08m
Multiple Airlines
Wed 7/83:48 pm
GSP
- MEM
1 stop17h 11m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$241
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
JAN
- CLT
1 stop12h 37m
American Airlines
Tue 7/2110:50 pm
CLT
- JAN
Nonstop1h 58m
American Airlines
Deal found 6/18![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- SAV
1 stop24h 06m
Multiple Airlines
Wed 7/2212:19 pm
SAV
- MEM
1 stop20h 40m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Fri 7/246:41 pm
CLT
- MEM
1 stop14h 18m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$254
Best flights from Mississippi to South CarolinaDiscover carefully curated flight deals from Mississippi to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 20, 2026.
Discover carefully curated flight deals from Mississippi to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- SAV
1 stop24h 06m
Multiple Airlines
Wed 7/2212:19 pm
SAV
- MEM
1 stop20h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:40 pm
MEM
- GSP
1 stop16h 45m
Allegiant Air
Sun 7/123:51 pm
GSP
- MEM
1 stop4h 59m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$288
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:15 pm
MEM
- CHS
1 stop3h 15m
Southwest
Wed 7/221:50 pm
CHS
- MEM
2 stops10h 00m
Southwest
Deal found 6/16![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:27 pm
BTR
- SAV
1 stop4h 32m
Delta
Sun 7/267:07 pm
SAV
- BTR
1 stop3h 49m
Delta
Deal found 6/18![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:23 pm
MEM
- CHS
1 stop6h 25m
American Airlines
Mon 8/107:48 pm
CHS
- MEM
1 stop4h 02m
American Airlines
Deal found 6/16![American Airlines logo]()
$316
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:22 pm
MEM
- CAE
1 stop5h 54m
United Airlines
Wed 7/86:25 am
CAE
- MEM
1 stop5h 40m
United Airlines
Deal found 6/17![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:04 pm
BTR
- SAV
1 stop3h 49m
Delta
Wed 7/157:07 pm
SAV
- BTR
1 stop3h 49m
Delta
Deal found 6/16![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:20 pm
MEM
- GSP
1 stop6h 20m
Southwest
Sat 11/77:05 am
GSP
- MEM
1 stop3h 10m
Southwest
Deal found 6/20![Southwest logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:03 pm
MEM
- CHS
1 stop19h 25m
Multiple Airlines
Mon 7/133:23 pm
CHS
- MEM
1 stop25h 18m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:00 pm
BTR
- SAV
1 stop4h 17m
Delta
Mon 7/206:43 am
SAV
- BTR
1 stop3h 56m
Delta
Deal found 6/15![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:15 am
MEM
- GSP
1 stop5h 17m
United Airlines
Wed 8/125:31 pm
GSP
- MEM
1 stop5h 25m
United Airlines
Deal found 6/19![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:20 am
MEM
- MYR
1 stop7h 20m
Southwest
Tue 9/86:30 pm
MYR
- MEM
1 stop4h 15m
Southwest
Deal found 6/18![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:52 pm
MEM
- GSP
1 stop3h 23m
Delta
Tue 7/285:44 am
GSP
- MEM
1 stop3h 02m
Delta
Deal found 6/16![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:00 am
MEM
- CAE
1 stop4h 44m
American Airlines
Tue 8/113:59 pm
CAE
- MEM
1 stop4h 46m
American Airlines
Deal found 6/15![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:00 pm
MEM
- GSP
1 stop4h 55m
Southwest
Tue 7/281:50 pm
GSP
- MEM
2 stops10h 35m
Southwest
Deal found 6/16![Southwest logo]()
$315
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:55 am
MEM
- CHS
1 stop7h 25m
Southwest
Mon 8/1012:05 pm
CHS
- MEM
2 stops9h 25m
Southwest
Deal found 6/16![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:30 am
MEM
- CAE
1 stop5h 42m
United Airlines
Wed 11/186:30 am
CAE
- MEM
1 stop5h 02m
United Airlines
Deal found 6/16![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:15 am
MEM
- GSP
1 stop5h 59m
Delta
Wed 7/226:45 am
GSP
- MEM
1 stop4h 47m
Delta
Deal found 6/17![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:47 pm
MEM
- CAE
1 stop4h 09m
American Airlines
Tue 12/15:06 am
CAE
- MEM
1 stop6h 06m
American Airlines
Deal found 6/15![American Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:25 am
MEM
- GSP
1 stop2h 50m
Southwest
Wed 7/158:25 am
GSP
- MEM
1 stop7h 35m
Southwest
Deal found 6/17![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:45 pm
MEM
- SAV
1 stop6h 02m
Delta
Sat 11/75:30 am
SAV
- MEM
1 stop4h 04m
Delta
Deal found 6/17![Delta logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:23 pm
BTR
- CLT
1 stop7h 16m
American Airlines
Sun 11/16:44 pm
CLT
- BTR
Nonstop2h 22m
American Airlines
Deal found 6/15![American Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:20 am
MEM
- MYR
1 stop7h 20m
Southwest
Mon 9/283:20 pm
MYR
- MEM
2 stops7h 35m
Southwest
Deal found 6/15![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:01 pm
MEM
- MYR
1 stop4h 29m
Delta
Tue 9/226:00 am
MYR
- MEM
1 stop4h 27m
Delta
Deal found 6/19![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:10 am
MEM
- MYR
1 stop4h 55m
Southwest
Sat 9/1912:10 pm
MYR
- MEM
2 stops7h 55m
Southwest
Deal found 6/15![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:35 am
BTR
- CLT
1 stop5h 31m
United Airlines
Tue 8/2511:45 am
CLT
- BTR
1 stop4h 45m
United Airlines
Deal found 6/15![United Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:16 pm
BTR
- CLT
1 stop5h 43m
American Airlines
Sun 8/28:15 pm
CLT
- BTR
Nonstop2h 15m
American Airlines
Deal found 6/18![American Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:13 pm
BTR
- SAV
1 stop4h 08m
Delta
Mon 9/75:35 am
SAV
- BTR
1 stop5h 04m
Delta
Deal found 6/15![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:45 am
MEM
- SAV
2 stops10h 10m
Southwest
Mon 9/211:05 pm
SAV
- MEM
2 stops8h 25m
Southwest
Deal found 6/18![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:20 am
BTR
- SAV
3 stops16h 39m
United Airlines
Sat 10/37:10 am
SAV
- BTR
1 stop5h 08m
United Airlines
Deal found 6/16![United Airlines logo]()
$508
Last-minute flights from Mississippi to South CarolinaDiscover last-minute flight deals from Mississippi to South Carolina. Data last updated June 20, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to South Carolina. Data last updated June 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:49 am
MEM
- GSP
1 stop22h 08m
Multiple Airlines
Fri 7/108:13 pm
GSP
- MEM
2 stops12h 46m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:49 am
MEM
- GSP
1 stop22h 08m
Multiple Airlines
Wed 7/83:48 pm
GSP
- MEM
1 stop17h 11m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:49 pm
MEM
- MYR
1 stop16h 01m
Multiple Airlines
Wed 8/53:17 pm
MYR
- MEM
1 stop17h 27m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:49 am
MEM
- CLT
1 stop11h 18m
Multiple Airlines
Sat 7/186:41 pm
CLT
- MEM
1 stop14h 18m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:40 pm
MEM
- GSP
1 stop16h 45m
Allegiant Air
Sun 7/193:51 pm
GSP
- MEM
1 stop4h 59m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- SAV
1 stop24h 06m
Multiple Airlines
Wed 7/2212:19 pm
SAV
- MEM
1 stop20h 40m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Fri 7/246:41 pm
CLT
- MEM
1 stop14h 18m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:49 am
MEM
- CLT
1 stop11h 18m
Multiple Airlines
Sun 7/196:41 pm
CLT
- MEM
2 stops24h 42m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:40 pm
MEM
- GSP
1 stop16h 45m
Allegiant Air
Sun 7/263:51 pm
GSP
- MEM
1 stop4h 59m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$266
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
JAN
- CLT
1 stop12h 37m
American Airlines
Tue 7/2110:50 pm
CLT
- JAN
Nonstop1h 58m
American Airlines
Deal found 6/18![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:49 am
MEM
- SAV
1 stop8h 06m
Multiple Airlines
Wed 7/2912:19 pm
SAV
- MEM
1 stop20h 40m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Wed 7/296:41 pm
CLT
- MEM
1 stop14h 18m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$183
One-way flights from Mississippi to South CarolinaSearch for one-way flight options from Mississippi to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 20, 2026.
Search for one-way flight options from Mississippi to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:04 am
MEM
- CLT
1 stop11h 09m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:04 pm
MEM
- CLT
1 stop27h 09m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:04 pm
MEM
- CLT
1 stop27h 09m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:04 pm
MEM
- CLT
1 stop20h 16m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:49 am
MEM
- CLT
1 stop11h 18m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:34 am
MEM
- CLT
1 stop11h 39m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- CLT
1 stop27h 18m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:49 am
MEM
- GSP
1 stop22h 08m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:03 pm
MEM
- CHS
1 stop13h 34m
Breeze Airways
Deal found 6/17![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:49 pm
MEM
- SAV
1 stop24h 06m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/303:57 pm
MEM
- MYR
1 stop16h 53m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$138
Find flight deals from Mississippi to South Carolina
Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated June 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $183 (Kiwi.com) |
One-way from | $81 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisSavannah
MEM - SAV
MEMSAV
Memphis
Fri 7/17
4:49 pm-5:55 pm
1 stop24h 06m
Savannah/Hilton Head
Wed 7/22
12:19 pm-7:59 am
1 stop20h 40m
$245
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Thu 7/9
8:40 pm-2:25 pm
1 stop16h 45m
Greenville
Sun 7/12
3:51 pm-7:50 pm
1 stop4h 59m
$288
MemphisCharleston
MEM - CHS
MEMCHS
Memphis
Wed 7/15
4:15 pm-8:30 pm
1 stop3h 15m
Charleston
Wed 7/22
1:50 pm-10:50 pm
2 stops10h 00m
$308
Baton RougeSavannah
BTR - SAV
BTRSAV
Baton Rouge Ryan
Thu 7/23
1:27 pm-6:59 pm
1 stop4h 32m
Savannah/Hilton Head
Sun 7/26
7:07 pm-9:56 pm
1 stop3h 49m
$309
Baton RougeSavannah
BTR - SAV
BTRSAV
Baton Rouge Ryan
Thu 7/9
7:04 pm-11:53 pm
1 stop3h 49m
Savannah/Hilton Head
Wed 7/15
7:07 pm-9:56 pm
1 stop3h 49m
$309
Baton RougeSavannah
BTR - SAV
BTRSAV
Baton Rouge Ryan
Mon 7/13
4:00 pm-9:17 pm
1 stop4h 17m
Savannah/Hilton Head
Mon 7/20
6:43 am-9:39 am
1 stop3h 56m
$309
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Fri 11/6
2:20 pm-9:40 pm
1 stop6h 20m
Greenville
Sat 11/7
7:05 am-9:15 am
1 stop3h 10m
$310
Quickest round-trip
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Fri 7/24
5:52 pm-10:15 pm
1 stop3h 23m
Greenville
Tue 7/28
5:44 am-7:46 am
1 stop3h 02m
$310
MemphisMyrtle Beach
MEM - MYR
MEMMYR
Memphis
Thu 9/3
11:20 am-7:40 pm
1 stop7h 20m
Myrtle Beach Intl
Tue 9/8
6:30 pm-9:45 pm
1 stop4h 15m
$314
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Fri 7/24
5:00 pm-10:55 pm
1 stop4h 55m
Greenville
Tue 7/28
1:50 pm-11:25 pm
2 stops10h 35m
$315
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
MEM-CLT
MEM-GSP
JAN-CLT
MEM-SAV
MEM-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to South Carolina
USMS-USSC
MEM-CLT
MEM-GSP
JAN-CLT
MEM-SAV
What is the cheapest month to book a flight from Mississippi to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $191). Flying from Mississippi to South Carolina in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mississippi to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 20, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Mississippi to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
7.9
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Overall
7.9
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Overall
7.9
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Overall
7.9
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Mississippi to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to South Carolina by cabin class
Find flights from Mississippi to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and South Carolina flights
Browse other Mississippi and South Carolina flight options. Last updated on June 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Mississippi after your stay in South Carolina
Mississippi to South Carolina flights
Consider these flights traveling from Mississippi to South Carolina.
Top 3 airlines flying from Mississippi to South Carolina
Discover the top 3 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$191 | Average$321 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$469 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$392 | FlexibilityNo cancel fee | On-time63% |