$88+ Cheap flights from Mississippi to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to South Carolina
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Cheapest flights from Mississippi to South CarolinaExplore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:04 pm
MEM
- CLT
1 stop18h 01m
Multiple Airlines
Wed 6/106:40 pm
CLT
- MEM
1 stop14h 05m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:04 pm
MEM
- CLT
1 stop20h 07m
Multiple Airlines
Wed 6/106:40 pm
CLT
- MEM
1 stop14h 05m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Sat 5/236:00 am
CLT
- MEM
1 stop6h 34m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Wed 5/275:50 pm
CLT
- MEM
1 stop24h 59m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:37 pm
MEM
- CLT
1 stop17h 28m
Multiple Airlines
Thu 5/289:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Fri 5/229:07 pm
CLT
- MEM
1 stop15h 27m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:37 pm
MEM
- CLT
1 stop17h 35m
Multiple Airlines
Thu 5/289:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:24 pm
MEM
- CLT
1 stop10h 16m
Multiple Airlines
Wed 6/35:50 pm
CLT
- MEM
1 stop14h 55m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:37 pm
MEM
- CLT
1 stop17h 35m
Multiple Airlines
Wed 5/273:16 pm
CLT
- MEM
1 stop27h 33m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:37 pm
MEM
- CLT
1 stop22h 06m
Multiple Airlines
Thu 5/219:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:39 pm
MEM
- CLT
1 stop16h 26m
Multiple Airlines
Thu 5/146:41 pm
CLT
- MEM
1 stop24h 08m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:37 pm
MEM
- CLT
1 stop22h 06m
Multiple Airlines
Thu 5/289:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$205
Best flights from Mississippi to South CarolinaDiscover carefully curated flight deals from Mississippi to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Mississippi to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:22 am
MEM
- GSP
1 stop22h 11m
Multiple Airlines
Mon 6/18:28 pm
GSP
- MEM
1 stop21h 04m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:30 am
MEM
- CHS
1 stop3h 33m
Delta
Sat 6/66:15 am
CHS
- MEM
1 stop3h 35m
Delta
Deal found 4/23![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MEM
- GSP
2 stops9h 20m
Southwest
Thu 5/216:25 am
GSP
- MEM
1 stop3h 15m
Southwest
Deal found 4/26![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:58 pm
MEM
- SAV
1 stop5h 55m
American Airlines
Mon 5/188:09 pm
SAV
- MEM
1 stop4h 38m
American Airlines
Deal found 4/23![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:15 am
MEM
- SAV
1 stop6h 01m
United Airlines
Tue 8/117:00 am
SAV
- MEM
1 stop7h 55m
United Airlines
Deal found 4/24![United Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:05 pm
MEM
- MYR
2 stops22h 43m
Multiple Airlines
Thu 6/2512:15 pm
MYR
- MEM
1 stop20h 08m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:54 pm
MEM
- GSP
1 stop4h 49m
Delta
Mon 5/187:42 pm
GSP
- MEM
1 stop4h 34m
Delta
Deal found 4/24![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:05 am
MEM
- MYR
1 stop5h 05m
Southwest
Tue 5/192:10 pm
MYR
- MEM
2 stops9h 40m
Southwest
Deal found 4/23![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:00 pm
GPT
- SAV
1 stop6h 53m
United Airlines
Tue 8/257:00 am
SAV
- GPT
1 stop7h 26m
United Airlines
Deal found 4/27![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:01 pm
JAN
- SAV
1 stop5h 39m
Delta
Tue 6/25:30 am
SAV
- JAN
1 stop4h 24m
Delta
Deal found 4/27![Delta logo]()
$328
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
MEM
- SAV
2 stops8h 25m
Southwest
Tue 9/291:10 pm
SAV
- MEM
2 stops9h 35m
Southwest
Deal found 4/26![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:07 pm
MEM
- GSP
1 stop3h 36m
Delta
Sun 5/315:40 am
GSP
- MEM
1 stop3h 06m
Delta
Deal found 4/24![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:38 pm
GPT
- SAV
1 stop4h 21m
American Airlines
Tue 6/307:01 am
SAV
- GPT
1 stop4h 13m
American Airlines
Deal found 4/25![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:35 pm
MEM
- CHS
1 stop6h 20m
Southwest
Mon 6/84:45 pm
CHS
- MEM
2 stops8h 10m
Southwest
Deal found 4/23![Southwest logo]()
$350
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:15 am
MEM
- SAV
1 stop6h 01m
United Airlines
Thu 7/163:14 pm
SAV
- MEM
1 stop7h 52m
United Airlines
Deal found 4/23![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:38 pm
GPT
- SAV
1 stop4h 21m
American Airlines
Mon 6/85:56 pm
SAV
- GPT
1 stop7h 05m
American Airlines
Deal found 4/27![American Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:07 pm
MEM
- MYR
1 stop3h 51m
Delta
Sat 5/306:00 am
MYR
- MEM
1 stop3h 50m
Delta
Deal found 4/27![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:15 pm
MEM
- GSP
2 stops7h 25m
Southwest
Mon 5/186:25 pm
GSP
- MEM
1 stop5h 35m
Southwest
Deal found 4/24![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:06 pm
JAN
- SAV
1 stop6h 47m
United Airlines
Wed 8/193:39 pm
SAV
- JAN
1 stop6h 39m
United Airlines
Deal found 4/27![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:07 pm
MEM
- MYR
1 stop3h 51m
Delta
Thu 6/46:00 am
MYR
- MEM
1 stop6h 39m
Delta
Deal found 4/23![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:06 pm
JAN
- SAV
1 stop6h 47m
United Airlines
Wed 8/123:39 pm
SAV
- JAN
1 stop4h 49m
United Airlines
Deal found 4/25![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:33 pm
BTR
- CLT
Nonstop2h 12m
American Airlines
Wed 5/138:06 pm
CLT
- BTR
Nonstop2h 18m
American Airlines
Deal found 4/24![American Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:35 pm
MEM
- CHS
1 stop6h 20m
Southwest
Sat 6/66:30 am
CHS
- MEM
1 stop3h 35m
Southwest
Deal found 4/28![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:44 am
MEM
- SAV
1 stop5h 36m
United Airlines
Wed 8/123:14 pm
SAV
- MEM
1 stop7h 43m
United Airlines
Deal found 4/27![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/194:25 pm
MOB
- SAV
1 stop3h 42m
Delta
Sun 6/215:39 am
SAV
- MOB
1 stop3h 56m
Delta
Deal found 4/28![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:15 am
JAN
- CLT
Nonstop2h 02m
American Airlines
Sun 6/216:53 pm
CLT
- JAN
Nonstop2h 06m
American Airlines
Deal found 4/24![American Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:25 pm
MEM
- GSP
1 stop4h 50m
Southwest
Tue 5/126:45 am
GSP
- MEM
1 stop3h 20m
Southwest
Deal found 4/23![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/114:42 pm
MEM
- CHS
1 stop6h 11m
United Airlines
Wed 8/123:25 pm
CHS
- MEM
1 stop7h 32m
United Airlines
Deal found 4/27![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:55 pm
MOB
- SAV
1 stop3h 58m
Delta
Sun 7/198:08 pm
SAV
- MOB
1 stop4h 17m
Delta
Deal found 4/28![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:09 pm
GPT
- SAV
1 stop4h 44m
American Airlines
Tue 5/127:11 am
SAV
- GPT
1 stop5h 50m
American Airlines
Deal found 4/23![American Airlines logo]()
$447
Last-minute flights from Mississippi to South CarolinaDiscover last-minute flight deals from Mississippi to South Carolina. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to South Carolina. Data last updated April 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:39 pm
MEM
- CLT
1 stop16h 26m
Multiple Airlines
Thu 5/146:41 pm
CLT
- MEM
1 stop24h 08m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Sat 5/236:00 am
CLT
- MEM
1 stop6h 34m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Wed 5/275:50 pm
CLT
- MEM
1 stop24h 59m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Fri 5/229:07 pm
CLT
- MEM
1 stop15h 27m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Fri 5/299:07 pm
CLT
- MEM
1 stop15h 27m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:37 pm
MEM
- CLT
1 stop22h 06m
Multiple Airlines
Thu 5/219:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:37 pm
MEM
- CLT
1 stop22h 06m
Multiple Airlines
Thu 5/289:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:37 pm
MEM
- CLT
1 stop22h 06m
Multiple Airlines
Wed 5/275:50 pm
CLT
- MEM
1 stop24h 59m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:37 pm
MEM
- CLT
1 stop17h 35m
Multiple Airlines
Thu 5/289:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:37 pm
MEM
- CLT
1 stop17h 35m
Multiple Airlines
Wed 5/273:16 pm
CLT
- MEM
1 stop27h 33m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:37 pm
MEM
- CLT
1 stop17h 28m
Multiple Airlines
Thu 5/289:07 pm
CLT
- MEM
1 stop11h 27m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:24 pm
MEM
- CLT
1 stop10h 16m
Multiple Airlines
Wed 6/35:50 pm
CLT
- MEM
1 stop14h 55m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$198
One-way flights from Mississippi to South CarolinaSearch for one-way flight options from Mississippi to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Mississippi to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:04 pm
MEM
- CLT
1 stop18h 01m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:39 pm
MEM
- CLT
1 stop16h 26m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:05 pm
MEM
- CLT
1 stop18h 39m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:39 pm
MEM
- CLT
1 stop18h 32m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:17 pm
MEM
- CLT
1 stop14h 57m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:37 pm
MEM
- CLT
1 stop22h 06m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:55 am
MEM
- CLT
1 stop13h 17m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:45 pm
MEM
- SAV
1 stop27h 03m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$120
This Trip.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:52 pm
MEM
- CLT
1 stop20h 31m
Frontier
Deal found 4/23![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:05 pm
MEM
- CLT
1 stop20h 09m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:37 pm
MEM
- CLT
1 stop17h 28m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:37 pm
MEM
- CHS
1 stop14h 01m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$143
Find flight deals from Mississippi to South Carolina
Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $172 (Kiwi.com) |
One-way from | $88 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Sun 5/24
8:22 am-7:33 am
1 stop22h 11m
Greenville
Mon 6/1
8:28 pm-4:32 pm
1 stop21h 04m
$281
MemphisCharleston
MEM - CHS
MEMCHS
Memphis
Tue 6/2
9:30 am-2:03 pm
1 stop3h 33m
Charleston
Sat 6/6
6:15 am-8:50 am
1 stop3h 35m
$288
MemphisMyrtle Beach
MEM - MYR
MEMMYR
Memphis
Fri 6/19
3:05 pm-2:48 pm
2 stops22h 43m
Myrtle Beach Intl
Thu 6/25
12:15 pm-7:23 am
1 stop20h 08m
$293
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Wed 5/20
6:00 am-4:20 pm
2 stops9h 20m
Greenville
Thu 5/21
6:25 am-8:40 am
1 stop3h 15m
$304
MemphisSavannah
MEM - SAV
MEMSAV
Memphis
Tue 5/12
3:58 pm-10:53 pm
1 stop5h 55m
Savannah/Hilton Head
Mon 5/18
8:09 pm-11:47 pm
1 stop4h 38m
$308
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Sat 5/16
5:54 pm-11:43 pm
1 stop4h 49m
Greenville
Mon 5/18
7:42 pm-11:16 pm
1 stop4h 34m
$311
MemphisMyrtle Beach
MEM - MYR
MEMMYR
Memphis
Sat 5/16
10:05 am-4:10 pm
1 stop5h 05m
Myrtle Beach Intl
Tue 5/19
2:10 pm-10:50 pm
2 stops9h 40m
$322
JacksonSavannah
JAN - SAV
JANSAV
Jackson-Evers Intl
Sat 5/30
5:01 pm-11:40 pm
1 stop5h 39m
Savannah/Hilton Head
Tue 6/2
5:30 am-8:54 am
1 stop4h 24m
$328
MemphisGreenville
MEM - GSP
MEMGSP
Memphis
Thu 5/28
7:07 pm-11:43 pm
1 stop3h 36m
Greenville
Sun 5/31
5:40 am-7:46 am
1 stop3h 06m
$329
MemphisSavannah
MEM - SAV
MEMSAV
Memphis
Wed 9/16
7:00 am-4:25 pm
2 stops8h 25m
Savannah/Hilton Head
Tue 9/29
1:10 pm-9:45 pm
2 stops9h 35m
$335
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
MEM-SAV
MEM-CHS
MEM-MYR
MEM-CLT
MEM-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to South Carolina
USMS-USSC
MEM-SAV
MEM-CHS
MEM-MYR
MEM-CLT
What is the cheapest month to book a flight from Mississippi to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $191). Flying from Mississippi to South Carolina in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mississippi to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 28, 2026.
See what other customers who have flown with Delta and American Airlines from Mississippi to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to South Carolina by cabin class
Find flights from Mississippi to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and South Carolina flights
Browse other Mississippi and South Carolina flight options. Last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Mississippi after your stay in South Carolina
Mississippi to South Carolina flights
Consider these flights traveling from Mississippi to South Carolina.
Top 2 airlines flying from Mississippi to South Carolina
Discover the top 2 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$191 | Average$321 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$193 | Average$436 | FlexibilityNo cancel fee | On-timeN/A |