HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Dakota

$135+ Cheap flights from Mississippi to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to South Dakota with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to South Dakota

Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated July 1, 2025.

Round-trip from

$244
(Delta)

One-way from

$135
(Mytrip)
From Mississippi to South Dakota
Search Deals
One-way flight from Mississippi to South Dakota
Search Deals

Find flight deals from Mississippi to South Dakota

Cheapest flights from Mississippi to South Dakota
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:20 pmGPT - FSD
1 stop7h 56mAmerican Airlines
Tue 10/285:05 pmFSD - GPT
1 stop6h 31mAmerican Airlines
Deal found 6/30$239
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:00 pmGPT - FSD
1 stop6h 06mDelta
Wed 9/35:00 amFSD - GPT
2 stops11h 13mDelta
Deal found 6/29$244
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/52:52 pmMEM - FSD
1 stop6h 31mAmerican Airlines
Mon 9/87:00 amFSD - MEM
1 stop6h 58mAmerican Airlines
Deal found 6/30$249
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/265:25 amMOB - FSD
1 stop7h 33mAmerican Airlines
Wed 9/37:00 amFSD - MOB
1 stop5h 03mAmerican Airlines
Deal found 6/30$259
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:39 pmBTR - FSD
1 stop6h 23mDelta
Wed 10/112:56 pmFSD - BTR
2 stops9h 16mDelta
Deal found 6/29$264
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/55:19 amMOB - RAP
1 stop5h 36mAmerican Airlines
Tue 8/125:39 amRAP - MOB
1 stop5h 11mAmerican Airlines
Deal found 6/30$269
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/292:52 pmMEM - RAP
1 stop7h 01mAmerican Airlines
Fri 10/31:12 pmRAP - MEM
1 stop6h 47mAmerican Airlines
Deal found 6/30$301
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/153:10 pmMEM - FSD
1 stop5h 10mUnited Airlines
Sat 7/198:00 amFSD - MEM
1 stop6h 46mUnited Airlines
Deal found 6/30$304
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/96:21 pmMEM - FSD
1 stop5h 23mDelta
Sat 7/125:15 amFSD - MEM
1 stop6h 06mDelta
Deal found 6/30$309
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/277:20 amBTR - FSD
1 stop5h 18mAmerican Airlines
Wed 10/11:21 pmFSD - BTR
1 stop4h 40mAmerican Airlines
Deal found 6/29$329
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/123:10 pmMEM - RAP
1 stop6h 35mUnited Airlines
Sat 7/195:30 amRAP - MEM
2 stops8h 16mUnited Airlines
Deal found 7/1$330
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:19 pmMEM - RAP
1 stop5h 13mDelta
Sat 8/234:25 pmRAP - MEM
1 stop4h 52mDelta
Deal found 7/1$333

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.

Fly from

Mississippi

Fly to

South Dakota

Route

Depart

Return

Price

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Sat 8/30

5:00 pm-11:06 pm

1 stop6h 06m

Sioux Falls Joe Foss Field

Wed 9/3

5:00 am-4:13 pm

2 stops11h 13m

$244

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Fri 9/5

2:52 pm-9:23 pm

1 stop6h 31m

Sioux Falls Joe Foss Field

Mon 9/8

7:00 am-1:58 pm

1 stop6h 58m

$249

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Tue 8/26

5:25 am-12:58 pm

1 stop7h 33m

Sioux Falls Joe Foss Field

Wed 9/3

7:00 am-12:03 pm

1 stop5h 03m

$259

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Sat 9/27

4:39 pm-11:02 pm

1 stop6h 23m

Sioux Falls Joe Foss Field

Wed 10/1

12:56 pm-10:12 pm

2 stops9h 16m

$264

MobileRapid City

MOB - RAP

MOBRAP

Mobile

Tue 8/5

5:19 am-9:55 am

1 stop5h 36m

Rapid City

Tue 8/12

5:39 am-11:50 am

1 stop5h 11m

$269

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Mon 9/29

2:52 pm-8:53 pm

1 stop7h 01m

Rapid City

Fri 10/3

1:12 pm-8:59 pm

1 stop6h 47m

$301

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Tue 7/15

3:10 pm-8:20 pm

1 stop5h 10m

Sioux Falls Joe Foss Field

Sat 7/19

8:00 am-2:46 pm

1 stop6h 46m

$304

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Sat 8/30

1:34 pm-9:03 pm

1 stop7h 29m

Sioux Falls Joe Foss Field

Wed 9/3

5:33 pm-11:32 pm

1 stop5h 59m

$319

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Sat 9/27

7:20 am-12:38 pm

1 stop5h 18m

Sioux Falls Joe Foss Field

Wed 10/1

1:21 pm-6:01 pm

1 stop4h 40m

$329

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Sat 7/12

3:10 pm-8:45 pm

1 stop6h 35m

Rapid City

Sat 7/19

5:30 am-2:46 pm

2 stops8h 16m

$330

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 41 results
1
2
3
...
5

Best time to book a flight from Mississippi to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Dakota
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated July 1, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
710 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to South Dakota one-way?

    The cheapest airlines for a one-way flight from Mississippi to South Dakota are Allegiant Air ($135), American Airlines ($181), and United Airlines ($212).

  • Can I find deals for flights from Mississippi to South Dakota that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Dakota.

  • Can I find deals for business class flights from Mississippi to South Dakota?

    Yes. Cheapflights offers flight deals from Mississippi to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Dakota?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to South Dakota (average of $334). Flying from Mississippi to South Dakota in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to South Dakota

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Seattle flights
Dallas/Fort Worth to LaGuardia flights
Los Angeles to John F Kennedy Intl flights
Los Angeles to Seattle flights
John F Kennedy Intl to Los Angeles flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to O'Hare Intl flights
Atlanta to John F Kennedy Intl flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to O'Hare Intl flights
John F Kennedy Intl to Las Vegas flights
Dallas/Fort Worth to Los Angeles flights
John F Kennedy Intl to Atlanta flights
Los Angeles to Newark flights
LaGuardia to Dallas/Fort Worth flights
Newark to Miami flights
John F Kennedy Intl to Miami flights
Newark to Los Angeles flights
Newark to Fort Lauderdale flights
Newark to O'Hare Intl flights
John F Kennedy Intl to Seattle flights
Dallas/Fort Worth to Las Vegas flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Honolulu flights
LaGuardia to Atlanta flights
LaGuardia to Fort Lauderdale flights
Atlanta to LaGuardia flights
John F Kennedy Intl to San Francisco flights
Los Angeles to Dallas/Fort Worth flights
LaGuardia to Miami flights
Newark to Seattle flights
Newark to Atlanta flights
O'Hare Intl to John F Kennedy Intl flights
Seattle to Los Angeles flights
San Francisco to Las Vegas flights
LaGuardia to O'Hare Intl flights
O'Hare Intl to LaGuardia flights
O'Hare Intl to Las Vegas flights
San Francisco to Los Angeles flights
John F Kennedy Intl to Dallas/Fort Worth flights
Dallas/Fort Worth to Newark flights
Dallas/Fort Worth to Orlando flights
O'Hare Intl to Dallas/Fort Worth flights
Los Angeles to San Francisco flights
San Francisco to Newark flights
Ontario to Seattle flights
John F Kennedy Intl to Denver flights
O'Hare Intl to Newark flights
Atlanta to Las Vegas flights
Atlanta to Newark flights

Top airline flying from Mississippi to South Dakota

Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$273Average$595FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.