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South Dakota

$221+ Cheap flights from Mississippi to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — RAP
Jun 21 — Jun 281
Sun 6/21
Sun 6/28
1 adult, Economy
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Cheap flight deals from Mississippi to South Dakota

Cheapest flights from Mississippi to South Dakota
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.

This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:46 pm
MEM
-
FSD
1 stop6h 45m
American Airlines
Thu 8/276:00 pm
FSD
-
MEM
1 stop4h 50m
American Airlines
Deal found 5/19$309
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:41 pm
MEM
-
RAP
1 stop4h 56m
Delta
Sun 8/1610:46 am
RAP
-
MEM
1 stop6h 14m
Delta
Deal found 5/21$319
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 am
MOB
-
FSD
1 stop6h 16m
American Airlines
Tue 8/1112:27 pm
FSD
-
MOB
1 stop5h 32m
American Airlines
Deal found 5/21$319
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:48 pm
MEM
-
FSD
1 stop6h 32m
American Airlines
Sun 6/75:35 pm
FSD
-
MEM
1 stop6h 24m
American Airlines
Deal found 5/19$339
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:20 pm
MEM
-
RAP
1 stop5h 15m
American Airlines
Sat 8/295:02 pm
RAP
-
MEM
1 stop4h 48m
American Airlines
Deal found 5/18$344
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:39 pm
MEM
-
RAP
1 stop4h 47m
Delta
Thu 7/166:48 am
RAP
-
MEM
2 stops12h 47m
Delta
Deal found 5/20$358
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:39 pm
MEM
-
RAP
1 stop4h 59m
Delta
Sat 6/204:29 pm
RAP
-
MEM
1 stop4h 52m
Delta
Deal found 5/20$361
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:35 pm
MEM
-
RAP
1 stop5h 41m
United Airlines
Tue 6/97:05 am
RAP
-
MEM
1 stop6h 24m
United Airlines
Deal found 5/21$369
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:06 pm
MEM
-
FSD
1 stop6h 12m
American Airlines
Sun 8/24:44 pm
FSD
-
MEM
1 stop7h 34m
American Airlines
Deal found 5/21$384
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:28 pm
MEM
-
FSD
1 stop7h 16m
United Airlines
Wed 10/289:14 am
FSD
-
MEM
1 stop4h 55m
United Airlines
Deal found 5/17$389
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:56 pm
MEM
-
FSD
2 stops9h 24m
American Airlines
Mon 6/295:35 pm
FSD
-
MEM
1 stop6h 24m
American Airlines
Deal found 5/19$399
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:33 pm
MEM
-
RAP
1 stop6h 55m
United Airlines
Wed 8/197:00 am
RAP
-
MEM
1 stop6h 50m
United Airlines
Deal found 5/20$399

Find flight deals from Mississippi to South Dakota

Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated May 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(American Airlines)

One-way from

$221
(Delta)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
Search Deals
From Mississippi to South Dakota
Search Deals
One-way flight from Mississippi to South Dakota
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Mon 8/10

6:41 pm-10:37 pm

1 stop4h 56m

Rapid City

Sun 8/16

6:48 am-6:39 pm

2 stops10h 51m

$324

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Fri 6/5

5:48 pm-12:20 am

1 stop6h 32m

Sioux Falls Joe Foss Field

Sun 6/7

5:35 pm-11:59 pm

1 stop6h 24m

$339

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Fri 6/5

4:10 pm-12:20 am

2 stops8h 10m

Sioux Falls Joe Foss Field

Tue 6/9

6:00 am-11:09 am

1 stop5h 09m

$344

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Thu 7/9

6:39 pm-10:26 pm

1 stop4h 47m

Rapid City

Thu 7/16

6:48 am-8:35 pm

2 stops12h 47m

$358

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sat 10/24

4:28 pm-11:44 pm

1 stop7h 16m

Sioux Falls Joe Foss Field

Wed 10/28

9:14 am-2:09 pm

1 stop4h 55m

$389

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Mon 6/22

5:48 pm-12:20 am

1 stop6h 32m

Sioux Falls Joe Foss Field

Mon 6/29

5:35 pm-11:59 pm

1 stop6h 24m

$394
Quickest round-trip

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Wed 7/8

6:00 am-10:15 am

1 stop4h 15m

Sioux Falls Joe Foss Field

Mon 7/13

4:26 pm-10:15 pm

1 stop5h 49m

$394

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Sat 8/15

8:30 am-12:24 pm

1 stop4h 54m

Rapid City

Wed 8/19

7:00 am-2:50 pm

1 stop6h 50m

$399

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Sat 11/14

9:40 am-8:46 pm

2 stops11h 06m

Sioux Falls Joe Foss Field

Tue 11/17

3:16 pm-10:56 pm

2 stops7h 40m

$409

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Fri 7/10

6:00 am-10:18 am

1 stop5h 18m

Rapid City

Thu 7/16

6:48 am-8:35 pm

2 stops12h 47m

$425

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/17

Showing 1-10 of 37 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Dakota
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated May 22, 2026.
Get a feel of what it's like to fly with American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,644 reviews

Crew

7.9

Food

6.4

Comfort

7.2

Overall

7.1

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,644 reviews
American Airlines
7.1
Good
11,644 reviews

Crew

7.9

Food

6.4

Comfort

7.2

Overall

7.1

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Dakota?

    Departing from Mississippi to South Dakota will take you 4h 56m. Airlines will cover a distance of 931 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mississippi to South Dakota that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Dakota.

  • Can I find deals for business class flights from Mississippi to South Dakota?

    Yes. Cheapflights offers flight deals from Mississippi to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to South Dakota

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to South Dakota

Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$338Average$588FlexibilityNo cancel feeOn-time71%

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