$284+ Cheap flights from South Dakota to Mississippi
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from South Dakota to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Dakota to MississippiExplore the most affordable flight options available from South Dakota to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from South Dakota to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:58 pm -
1 stop5h 44m
Sun 12/65:36 pm -
1 stop6h 53m
Deal found 9/18![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:31 pm -
1 stop4h 45m
Sat 10/36:25 pm -
1 stop4h 46m
Deal found 9/14![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:59 pm -
1 stop5h 25m
Tue 10/65:04 am -
1 stop7h 09m
Deal found 9/17![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop5h 07m
Tue 9/295:34 pm -
1 stop6h 55m
Deal found 9/14![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:31 pm -
1 stop4h 45m
Tue 9/292:36 pm -
2 stops9h 08m
Deal found 9/14![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
2 stops9h 53m
Sat 10/312:05 pm -
2 stops8h 35m
Deal found 9/14![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop8h 13m
Sun 10/116:25 pm -
1 stop4h 46m
Deal found 9/18![United Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:58 pm -
1 stop5h 15m
Thu 12/105:00 am -
1 stop7h 28m
Deal found 9/17![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:58 pm -
1 stop5h 44m
Sun 11/85:44 am -
1 stop6h 44m
Deal found 9/18![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:32 am -
1 stop5h 07m
Wed 11/44:23 pm -
1 stop7h 21m
Deal found 9/15![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:20 am -
1 stop4h 53m
Sat 10/245:04 am -
1 stop7h 09m
Deal found 9/15![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 am -
2 stops10h 34m
Tue 10/610:50 am -
2 stops9h 30m
Deal found 9/17![United Airlines logo]()
$428
Best flights from South Dakota to MississippiDiscover carefully curated flight deals from South Dakota to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from South Dakota to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/610:00 am -
1 stop7h 44m
Mon 2/82:38 pm -
1 stop7h 45m
Deal found 9/16![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/55:15 am -
1 stop6h 06m
Mon 2/87:00 am -
1 stop5h 11m
Deal found 9/13![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:59 pm -
1 stop5h 25m
Tue 10/65:04 am -
1 stop7h 09m
Deal found 9/17![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:31 pm -
1 stop4h 45m
Sat 10/36:25 pm -
1 stop4h 46m
Deal found 9/14![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:20 am -
1 stop4h 34m
Sat 10/102:29 pm -
1 stop6h 44m
Deal found 9/17![American Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop8h 13m
Sun 10/116:25 pm -
1 stop4h 46m
Deal found 9/18![United Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:05 pm -
2 stops8h 48m
Sat 10/31:32 pm -
1 stop6h 15m
Deal found 9/14![Delta logo]()
$464
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:59 pm -
1 stop4h 59m
Tue 9/295:30 am -
1 stop6h 46m
Deal found 9/14![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:32 am -
1 stop5h 07m
Wed 11/44:23 pm -
1 stop7h 21m
Deal found 9/14![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:53 pm -
1 stop6h 09m
Wed 11/412:15 pm -
1 stop5h 12m
Deal found 9/16![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
2 stops8h 22m
Sat 10/32:00 pm -
2 stops9h 11m
Deal found 9/13![United Airlines logo]()
$431
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:30 am -
1 stop5h 47m
Sat 10/246:00 am -
1 stop13h 55m
Deal found 9/17![Delta logo]()
$538
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:53 pm -
1 stop6h 09m
Sat 10/175:40 am -
1 stop6h 33m
Deal found 9/15![American Airlines logo]()
$467
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:42 am -
2 stops9h 56m
Sat 10/242:00 pm -
2 stops9h 11m
Deal found 9/15![United Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop4h 40m
Sat 10/37:49 am -
2 stops10h 22m
Deal found 9/13![American Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:00 am -
2 stops10h 32m
Sat 1/3012:05 pm -
2 stops11h 05m
Deal found 9/16![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:46 pm -
2 stops7h 52m
Tue 9/2910:50 am -
2 stops12h 21m
Deal found 9/14![United Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop4h 40m
Sun 10/45:02 pm -
1 stop4h 55m
Deal found 9/15![American Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:39 am -
2 stops11h 05m
Sat 10/2411:10 am -
2 stops12h 20m
Deal found 9/17![Delta logo]()
$734
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:48 am -
2 stops10h 50m
Sat 10/316:55 am -
2 stops9h 30m
Deal found 9/17![United Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 am -
1 stop27h 00m
Sun 10/256:30 pm -
1 stop25h 25m
Deal found 9/17![Delta logo]()
$807
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:58 pm -
1 stop5h 33m
Thu 12/1011:44 am -
1 stop5h 43m
Deal found 9/16![American Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/265:30 am -
2 stops6h 53m
Sat 1/307:00 am -
2 stops10h 03m
Deal found 9/14![United Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:54 pm -
1 stop5h 03m
Sun 10/115:04 am -
1 stop7h 09m
Deal found 9/18![American Airlines logo]()
$678
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:50 am -
2 stops7h 42m
Sat 10/101:55 pm -
2 stops9h 49m
Deal found 9/15![United Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:30 am -
2 stops9h 10m
Sun 10/2512:06 pm -
1 stop7h 49m
Deal found 9/17![Delta logo]()
$1,002
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:54 pm -
1 stop5h 04m
Mon 10/265:03 am -
1 stop7h 10m
Deal found 9/16![American Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
2 stops10h 12m
Sun 10/42:00 pm -
2 stops9h 44m
Deal found 9/15![United Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:56 pm -
1 stop4h 57m
Sat 10/312:14 pm -
2 stops10h 09m
Deal found 9/14![American Airlines logo]()
$830
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:50 am -
2 stops8h 22m
Sun 10/112:00 pm -
2 stops9h 11m
Deal found 9/18![United Airlines logo]()
$725
Last-minute flights from South Dakota to MississippiDiscover last-minute flight deals from South Dakota to Mississippi. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to Mississippi. Data last updated September 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop5h 07m
Tue 9/295:34 pm -
1 stop6h 55m
Deal found 9/14![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:31 pm -
1 stop4h 45m
Tue 9/292:36 pm -
2 stops9h 08m
Deal found 9/14![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:31 pm -
1 stop4h 45m
Sat 9/262:36 pm -
2 stops9h 08m
Deal found 9/14![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:31 pm -
1 stop4h 45m
Sat 10/36:25 pm -
1 stop4h 46m
Deal found 9/14![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
2 stops9h 53m
Sat 10/312:05 pm -
2 stops8h 35m
Deal found 9/14![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
2 stops8h 22m
Sat 10/32:00 pm -
2 stops9h 11m
Deal found 9/13![United Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:59 pm -
1 stop5h 25m
Tue 10/65:04 am -
1 stop7h 09m
Deal found 9/17![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 am -
2 stops10h 34m
Tue 10/610:50 am -
2 stops9h 30m
Deal found 9/17![United Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop8h 13m
Sun 10/116:25 pm -
1 stop4h 46m
Deal found 9/18![United Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:20 am -
1 stop4h 34m
Sat 10/102:29 pm -
1 stop6h 44m
Deal found 9/17![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:20 am -
1 stop4h 53m
Sat 10/245:04 am -
1 stop7h 09m
Deal found 9/15![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:32 am -
1 stop5h 07m
Wed 11/44:23 pm -
1 stop7h 21m
Deal found 9/15![United Airlines logo]()
$419
One-way flights from South Dakota to MississippiSearch for one-way flight options from South Dakota to Mississippi. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from South Dakota to Mississippi. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:20 am -
1 stop4h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:46 pm -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:58 pm -
3 stops47h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop5h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:56 pm -
3 stops38h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:05 pm -
2 stops10h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/27:03 am -
2 stops10h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$415
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:56 pm -
1 stop4h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop5h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:35 am -
2 stops10h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/27:40 am -
3 stops13h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:26 am -
2 stops10h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$470
Find flight deals from South Dakota to Mississippi
Keep the following information in mind while searching for South Dakota to Mississippi flight deals. Data was last updated September 19, 2026.
Round-trip from | $339 (United Airlines) |
|---|---|
One-way from | $284 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from South Dakota to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Wed 10/21
6:20 am-11:04 am
1 stop4h 44m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Tue 3/2
7:03 am-1:47 pm
1 stop6h 44m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Wed 10/21
1:46 pm-11:16 pm
2 stops9h 30m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Sat 10/24
6:00 am-2:46 pm
2 stops8h 46m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Sat 2/6
10:00 am-5:44 pm
1 stop7h 44m
Memphis
Mon 2/8
2:38 pm-10:23 pm
1 stop7h 45m
$339
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Fri 2/5
5:15 am-11:21 am
1 stop6h 06m
Memphis
Mon 2/8
7:00 am-12:11 pm
1 stop5h 11m
$339
Sioux FallsMemphis
FSD Sioux Falls Joe Foss Field - MEM Memphis
FSDMEM
Sioux Falls Joe Foss Field
Tue 9/29
6:31 pm-11:16 pm
1 stop4h 45m
Memphis
Sat 10/3
6:25 pm-11:11 pm
1 stop4h 46m
$369
Sioux FallsGulfport
FSD Sioux Falls Joe Foss Field - GPT Gulfport Biloxi Regional
FSDGPT
Sioux Falls Joe Foss Field
Fri 10/2
5:59 pm-11:24 pm
1 stop5h 25m
Gulfport Biloxi Regional
Tue 10/6
5:04 am-12:13 pm
1 stop7h 09m
$399
Sioux FallsJackson
FSD Sioux Falls Joe Foss Field - JAN Jackson-Evers Intl
FSDJAN
Sioux Falls Joe Foss Field
Thu 10/1
6:00 am-11:47 am
1 stop5h 47m
Jackson-Evers Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$403
Sioux FallsJackson
FSD Sioux Falls Joe Foss Field - JAN Jackson-Evers Intl
FSDJAN
Sioux Falls Joe Foss Field
Thu 10/1
1:05 pm-11:21 pm
2 stops10h 16m
Jackson-Evers Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$408
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from South Dakota to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from South Dakota with our price prediction graph.
FSD-MEM
FSD-JAN
FSD-MOB
RAP-JAN
RAP-BTR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to Mississippi
USSD-USMS
FSD-MEM
FSD-JAN
FSD-MOB
RAP-JAN
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 19, 2026.
Read reviews from past customers who have flown American Airlines from South Dakota to Mississippi. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.2
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.2
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from South Dakota to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Dakota to Mississippi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Dakota to Mississippi by cabin class
Find flights from South Dakota to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Dakota and Mississippi flights
Browse other South Dakota and Mississippi flight options. Last updated on September 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mississippi
Find the right flight back to South Dakota after your stay in Mississippi
South Dakota to Mississippi flights
Consider these flights traveling from South Dakota to Mississippi.
Top airline flying from South Dakota to Mississippi
Discover the top airline that operate flights from South Dakota to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$478 | FlexibilityNo cancel fee | On-time71% |