HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$216+ Cheap flights from Greenville to St. Louis (GSP - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
May 19 — May 261
Mon 5/19
Mon 5/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Priceline
3 stars

Round-trip from

$270
(American Airlines)

One-way from

$216
(American Airlines)

Popular in

September

Cheapest in

August

Average price

$386
Provider with most accurate pricing for Greenville-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Lambert-St Louis flights.
Search Deals
From Greenville to Lambert-St Louis
Search Deals
One-way flight from Greenville to Lambert-St Louis
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from Greenville to St. Louis

Cheapest flights from Greenville to St. Louis
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2025.

This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2811:23 amGSP - STL
1 stop5h 52mAmerican Airlines
Fri 7/45:37 amSTL - GSP
1 stop5h 15mAmerican Airlines
Deal found 5/13$270
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:00 pmGSP - STL
1 stop3h 39mDelta
Tue 6/36:00 amSTL - GSP
1 stop3h 36mDelta
Deal found 5/12$287
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/48:10 amGSP - STL
2 stops9h 15mSouthwest
Wed 6/1112:15 pmSTL - GSP
1 stop5h 10mSouthwest
Deal found 5/13$292
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/175:45 pmGSP - STL
1 stop6h 49mUnited Airlines
Thu 7/248:00 amSTL - GSP
2 stops9h 57mUnited Airlines
Deal found 5/13$422
This Mytrip deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/203:34 pmGSP - STL
3 stops28h 07mMultiple Airlines
Wed 7/2311:24 amSTL - GSP
3 stops32h 04mMultiple Airlines
Deal found 5/12$487

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2025.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.

Fly from

Greenville

Fly to

St. Louis

Route

Depart

Return

Price

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sat 6/28

11:23 am-4:15 pm

1 stop5h 52m

Lambert-St Louis

Fri 7/4

5:37 am-11:52 am

1 stop5h 15m

$270

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 5/28

6:00 pm-8:39 pm

1 stop3h 39m

Lambert-St Louis

Tue 6/3

6:00 am-10:36 am

1 stop3h 36m

$287

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 6/4

8:10 am-4:25 pm

2 stops9h 15m

Lambert-St Louis

Wed 6/11

12:15 pm-6:25 pm

1 stop5h 10m

$292

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 7/17

5:45 pm-11:34 pm

1 stop6h 49m

Lambert-St Louis

Thu 7/24

8:00 am-6:57 pm

2 stops9h 57m

$422

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 7/20

3:34 pm-6:41 pm

3 stops28h 07m

Lambert-St Louis

Wed 7/23

11:24 am-8:28 pm

3 stops32h 04m

$487

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 5/21

9:09 am-12:52 pm

1 stop4h 43m

$216

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 5/21

8:10 am-4:25 pm

2 stops9h 15m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/13

Compare providers for flights from Greenville to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to St. Louis in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
PricelinePrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-St. Louis flights, Cheapflights users trust Priceline the most. Priceline has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to St. Louis

What is the cheapest month to book a flight from Greenville to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $311). Flying from Greenville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to STL?

Find hourly flight availability from Greenville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 14, 2025.

When flying from Greenville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the evening.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 14, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Greenville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,290 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,290 reviews
Southwest
8.0
Very good
4,290 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,949 reviews
Southwest
8.0
Very good
4,290 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,726 reviews
Southwest
8.0
Very good
4,290 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,290 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Greenville to St. Louis round-trip?

    According to our current data, American Airlines ($270), Delta ($287), and Southwest ($292) offers the cheapest pricing from Greenville to St. Louis. American Airlines is priced at 27% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Greenville to St. Louis one-way?

    $216 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $221 and $354, respectively.

  • Can I find deals for flights from Greenville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Greenville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to St. Louis.

  • Can I find deals for business class flights from Greenville to St. Louis?

    Yes. Cheapflights offers flight deals from Greenville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $311). Flying from Greenville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Fenton
Maryland Heights
Fairview Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Glencoe
Alton
Farmington
O'Fallon

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to St. Louis flights
Charlotte to Kansas City flights
Charlotte to Springfield flights
Columbia to St. Louis flights
Augusta to St. Louis flights
Charleston to St. Louis flights
Columbia to Kansas City flights
Greenville to Springfield flights
Greenville to Kansas City flights
Charleston to Kansas City flights
Savannah to St. Louis flights
Myrtle Beach to Kansas City flights
Charleston to Springfield flights
Savannah to Springfield flights
Savannah to Kansas City flights
Myrtle Beach to St. Louis flights
Charlotte to Joplin flights
Columbia to Springfield flights
Myrtle Beach to Springfield flights
Augusta to Kansas City flights
Hilton Head Island to Kansas City flights
Hilton Head Island to St. Louis flights
Charlotte to Columbia flights
Myrtle Beach to Joplin flights
Columbia to Columbia flights
Florence to St. Louis flights
Florence to Kansas City flights
Charlotte to Fort Leonard Wood flights
Charleston to Columbia flights
Augusta to Columbia flights

Top 3 airlines flying from Greenville to St. Louis

Discover the top 3 airlines that operate flights from Greenville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$241Average$374FlexibilityNo cancel feeOn-time71%
DeltaCheapest$271Average$385FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$286Average$346FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.