$130+ Cheap flights from St. Louis to Greenville (STL - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Greenville
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Best
Last-minute
One-way
Cheapest flights from St. Louis to GreenvilleExplore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:25 am
STL
- GSP
1 stop5h 07m
United Airlines
Tue 9/110:33 am
GSP
- STL
1 stop7h 33m
United Airlines
Deal found 7/27![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:50 pm
STL
- GSP
2 stops7h 05m
Southwest
Thu 9/36:55 pm
GSP
- STL
1 stop4h 15m
Southwest
Deal found 7/25![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:45 am
STL
- GSP
2 stops7h 40m
Southwest
Tue 9/17:00 am
GSP
- STL
2 stops8h 10m
Southwest
Deal found 7/27![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:30 pm
STL
- GSP
1 stop4h 30m
Southwest
Mon 10/128:40 pm
GSP
- STL
1 stop3h 55m
Southwest
Deal found 7/28![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:20 pm
STL
- GSP
2 stops7h 25m
Southwest
Mon 10/56:25 am
GSP
- STL
2 stops6h 50m
Southwest
Deal found 7/29![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:40 am
STL
- GSP
1 stop7h 40m
Southwest
Wed 9/98:15 am
GSP
- STL
2 stops7h 55m
Southwest
Deal found 7/26![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:52 pm
STL
- GSP
1 stop6h 40m
Delta
Mon 9/76:00 am
GSP
- STL
1 stop4h 20m
Delta
Deal found 7/28![Delta logo]()
$294
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:50 pm
STL
- GSP
1 stop3h 55m
Southwest
Mon 10/128:40 pm
GSP
- STL
1 stop3h 55m
Southwest
Deal found 7/28![Southwest logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- GSP
2 stops43h 36m
Multiple Airlines
Fri 8/288:45 pm
GSP
- STL
1 stop20h 26m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:05 am
STL
- GSP
2 stops9h 00m
Southwest
Fri 9/184:40 pm
GSP
- STL
1 stop6h 05m
Southwest
Deal found 7/28![Southwest logo]()
$314
Best flights from St. Louis to GreenvilleDiscover carefully curated flight deals from St. Louis to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from St. Louis to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:30 pm
STL
- GSP
1 stop3h 30m
Southwest
Mon 10/128:40 pm
GSP
- STL
1 stop3h 55m
Southwest
Deal found 7/26![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:52 pm
STL
- GSP
1 stop6h 40m
Delta
Mon 9/76:00 am
GSP
- STL
1 stop4h 20m
Delta
Deal found 7/28![Delta logo]()
$294
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 pm
STL
- GSP
1 stop5h 47m
United Airlines
Wed 11/186:30 am
GSP
- STL
1 stop5h 02m
United Airlines
Deal found 7/28![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:45 pm
STL
- GSP
1 stop4h 55m
Southwest
Fri 9/184:40 pm
GSP
- STL
1 stop6h 05m
Southwest
Deal found 7/26![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:00 pm
STL
- GSP
1 stop4h 59m
Delta
Mon 10/127:04 pm
GSP
- STL
1 stop5h 50m
Delta
Deal found 7/27![Delta logo]()
$328
Last-minute flights from St. Louis to GreenvilleDiscover last-minute flight deals from St. Louis to Greenville. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Greenville. Data last updated July 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:34 pm
STL
- GSP
2 stops20h 33m
Multiple Airlines
Fri 8/218:45 pm
GSP
- STL
1 stop20h 26m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:20 am
STL
- GSP
1 stop6h 00m
Southwest
Fri 8/217:00 am
GSP
- STL
1 stop4h 10m
Southwest
Deal found 7/28![Southwest logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- GSP
2 stops21h 09m
Multiple Airlines
Fri 8/218:45 pm
GSP
- STL
1 stop20h 26m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:45 pm
STL
- GSP
1 stop4h 50m
Southwest
Fri 8/216:55 pm
GSP
- STL
1 stop4h 10m
Southwest
Deal found 7/28![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:50 pm
STL
- GSP
2 stops7h 05m
Southwest
Thu 9/36:55 pm
GSP
- STL
1 stop4h 15m
Southwest
Deal found 7/25![Southwest logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- GSP
2 stops43h 36m
Multiple Airlines
Fri 8/288:45 pm
GSP
- STL
1 stop20h 26m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:15 am
STL
- GSP
2 stops8h 05m
Southwest
Fri 8/284:40 pm
GSP
- STL
2 stops6h 25m
Southwest
Deal found 7/24![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:25 am
STL
- GSP
1 stop5h 07m
United Airlines
Tue 9/110:33 am
GSP
- STL
1 stop7h 33m
United Airlines
Deal found 7/27![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:45 am
STL
- GSP
2 stops7h 40m
Southwest
Tue 9/17:00 am
GSP
- STL
2 stops8h 10m
Southwest
Deal found 7/27![Southwest logo]()
$269
One-way flights from St. Louis to GreenvilleSearch for one-way flight options from St. Louis to Greenville. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from St. Louis to Greenville. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:45 pm
STL
- GSP
1 stop3h 10m
Southwest
Deal found 7/28![Southwest logo]()
$130
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:00 am
STL
- GSP
2 stops10h 05m
United Airlines
Deal found 7/28![United Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:17 pm
STL
- GSP
2 stops43h 49m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:34 pm
STL
- GSP
2 stops23h 59m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:35 am
STL
- GSP
2 stops21h 26m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:45 pm
STL
- GSP
3 stops39h 41m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:57 pm
STL
- GSP
2 stops14h 00m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$187
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:00 am
STL
- GSP
1 stop4h 20m
Southwest
Deal found 7/28![Southwest logo]()
$199
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:42 am
STL
- GSP
1 stop7h 01m
American Airlines
Deal found 7/25![American Airlines logo]()
$209
Find flight deals from St. Louis to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (United Airlines) |
One-way from | $130 (Southwest) |
Popular in | January |
Cheapest in | October |
Average price | $510 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 10/7
4:30 pm-9:00 pm
1 stop3h 30m
Greenville
Mon 10/12
8:40 pm-11:35 pm
1 stop3h 55m
$259
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Thu 9/3
12:52 pm-8:32 pm
1 stop6h 40m
Greenville
Mon 9/7
6:00 am-9:20 am
1 stop4h 20m
$294
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Thu 9/17
3:45 pm-9:40 pm
1 stop4h 55m
Greenville
Fri 9/18
4:40 pm-9:45 pm
1 stop6h 05m
$321
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Fri 10/9
12:00 pm-5:59 pm
1 stop4h 59m
Greenville
Mon 10/12
7:04 pm-11:54 pm
1 stop5h 50m
$328
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 11/17
5:00 pm-11:47 pm
1 stop5h 47m
Greenville
Wed 11/18
6:30 am-10:32 am
1 stop5h 02m
$339
Cheapest one-way
Quickest one-way
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 8/19
4:45 pm-8:55 pm
1 stop3h 10m
$130
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 8/19
8:00 am-7:05 pm
2 stops10h 05m
$135
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sun 8/23
6:17 pm-3:06 pm
2 stops43h 49m
$136
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Sun 8/16
6:34 pm-7:33 pm
2 stops23h 59m
$143
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Wed 8/12
4:57 pm-7:57 am
2 stops14h 00m
$187
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Greenville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
STL-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Greenville
What is the cheapest month to book a flight from St. Louis to Greenville?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $297). Flying from St. Louis to Greenville in January is currently the most expensive (average of $841). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Greenville?
Airfare is typical for this route at the moment.
St. Louis to Greenville flights typically cost between $253 and $529 in August.The cheapest round-trip price found within the last 5 days was $259 on United Airlines (Aug 25-Sep 1).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 29, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from St. Louis to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
St. Louis and Greenville flights
Browse other St. Louis and Greenville flight options. Last updated on July 29, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Greenville
Discover the top 3 airlines that operate flights from St. Louis to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$486 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$253 | Average$333 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$521 | FlexibilityNo cancel fee | On-time63% |