$91+ Cheap flights from St. Louis (STL) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from St. Louis to South CarolinaExplore the most affordable flight options available from St. Louis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from St. Louis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:39 pm -
1 stop22h 42m
Mon 9/149:32 am -
1 stop8h 02m
Deal found 8/3![Frontier logo]()
$190
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:02 pm -
1 stop19h 48m
Mon 8/318:56 am -
1 stop7h 32m
Deal found 8/6![Frontier logo]()
$191
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:23 pm -
1 stop14h 38m
Mon 8/318:56 am -
1 stop7h 32m
Deal found 8/3![Frontier logo]()
$205
This Expedia deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:10 pm -
1 stop21h 41m
Mon 10/197:46 pm -
1 stop24h 29m
Deal found 8/3![Frontier logo]()
$206
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:58 pm -
1 stop19h 28m
Wed 9/29:52 pm -
1 stop19h 19m
Deal found 8/3![Frontier logo]()
$211
This Orbitz deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:10 pm -
1 stop21h 41m
Sun 10/1810:02 pm -
1 stop22h 37m
Deal found 8/3![Frontier logo]()
$220
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm -
1 stop23h 35m
Fri 9/119:32 am -
1 stop8h 02m
Deal found 8/4![Frontier logo]()
$221
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:54 am -
Nonstop1h 55m
Sun 9/611:00 am -
Nonstop1h 56m
Deal found 8/2![American Airlines logo]()
$226
This Travelocity deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:10 pm -
1 stop21h 41m
Fri 10/238:11 pm -
1 stop24h 28m
Deal found 8/4![Frontier logo]()
$229
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/305:02 pm -
1 stop19h 48m
Wed 9/29:52 pm -
1 stop19h 19m
Deal found 8/6![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:02 pm -
1 stop14h 36m
Sat 9/58:56 pm -
2 stops21h 26m
Deal found 8/3![Multiple Airlines logo]()
$231
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:35 pm -
Nonstop2h 00m
Mon 9/145:20 pm -
Nonstop2h 05m
Deal found 8/5![Southwest logo]()
$236
Best flights from St. Louis to South CarolinaDiscover carefully curated flight deals from St. Louis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from St. Louis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am -
1 stop4h 54m
Sun 9/67:13 am -
1 stop5h 43m
Deal found 8/3![Delta logo]()
$251
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:40 pm -
Nonstop2h 00m
Mon 8/316:35 am -
1 stop4h 35m
Deal found 8/3![Southwest logo]()
$260
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:40 am -
1 stop4h 41m
Sat 9/56:25 am -
1 stop6h 38m
Deal found 8/5![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:22 am -
1 stop5h 16m
Mon 9/145:15 pm -
1 stop6h 27m
Deal found 8/6![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:23 pm -
2 stops40h 42m
Fri 8/281:13 pm -
1 stop27h 58m
Deal found 8/6![Multiple Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:05 am -
1 stop4h 15m
Wed 10/288:10 am -
1 stop4h 25m
Deal found 8/4![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop6h 26m
Sun 9/67:40 am -
1 stop5h 16m
Deal found 8/3![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:35 pm -
Nonstop2h 00m
Thu 9/247:15 pm -
1 stop3h 55m
Deal found 8/5![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:20 pm -
1 stop3h 39m
Mon 10/127:46 pm -
1 stop5h 08m
Deal found 8/6![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:59 pm -
1 stop7h 29m
Sun 8/306:25 am -
1 stop4h 47m
Deal found 8/6![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:20 am -
2 stops9h 00m
Wed 10/78:10 am -
1 stop4h 25m
Deal found 8/5![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:14 am -
1 stop4h 56m
Mon 10/127:46 pm -
1 stop5h 08m
Deal found 8/4![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:35 am -
1 stop5h 37m
Sun 9/135:09 am -
1 stop4h 21m
Deal found 8/7![American Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:50 am -
1 stop7h 13m
Tue 9/15:38 pm -
1 stop4h 39m
Deal found 8/3![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:45 am -
2 stops9h 45m
Thu 9/2411:50 am -
Nonstop1h 55m
Deal found 8/6![Southwest logo]()
$270
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:13 pm -
1 stop5h 02m
Sun 9/274:49 pm -
1 stop4h 55m
Deal found 8/6![American Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop6h 26m
Mon 9/79:33 am -
1 stop6h 00m
Deal found 8/2![Delta logo]()
$290
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:00 am -
1 stop4h 35m
Mon 10/126:20 am -
1 stop6h 53m
Deal found 8/4![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:15 am -
1 stop6h 45m
Sun 9/64:00 pm -
1 stop5h 25m
Deal found 8/2![Southwest logo]()
$272
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:59 pm -
1 stop3h 32m
Tue 9/229:38 am -
1 stop4h 45m
Deal found 8/2![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am -
1 stop7h 25m
Wed 11/412:25 pm -
1 stop6h 04m
Deal found 8/4![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:30 am -
1 stop5h 46m
Wed 10/289:50 am -
2 stops8h 01m
Deal found 8/6![United Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:20 am -
1 stop4h 45m
Mon 10/59:00 pm -
1 stop3h 35m
Deal found 8/6![Southwest logo]()
$275
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:02 am -
1 stop5h 49m
Sun 12/1312:21 pm -
1 stop6h 42m
Deal found 8/4![American Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:05 am -
2 stops8h 35m
Tue 10/201:55 pm -
2 stops7h 05m
Deal found 8/2![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:25 am -
1 stop5h 38m
Sat 9/122:48 pm -
1 stop6h 12m
Deal found 8/2![United Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:25 am -
1 stop4h 16m
Mon 11/95:30 am -
1 stop4h 23m
Deal found 8/6![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:54 pm -
1 stop5h 46m
Mon 9/146:00 am -
1 stop5h 15m
Deal found 8/3![American Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:50 pm -
2 stops7h 40m
Tue 9/158:30 am -
2 stops9h 15m
Deal found 8/5![Southwest logo]()
$285
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:30 am -
1 stop7h 32m
Fri 9/116:20 am -
1 stop6h 37m
Deal found 8/6![United Airlines logo]()
$352
Last-minute flights from St. Louis to South CarolinaDiscover last-minute flight deals from St. Louis to South Carolina. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to South Carolina. Data last updated August 7, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:02 pm -
1 stop19h 48m
Mon 8/318:56 am -
1 stop7h 32m
Deal found 8/6![Frontier logo]()
$191
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:23 pm -
1 stop14h 38m
Mon 8/318:56 am -
1 stop7h 32m
Deal found 8/3![Frontier logo]()
$205
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:58 pm -
1 stop19h 28m
Wed 9/29:52 pm -
1 stop19h 19m
Deal found 8/3![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:02 pm -
1 stop14h 36m
Sat 9/58:56 pm -
2 stops21h 26m
Deal found 8/3![Multiple Airlines logo]()
$231
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/305:02 pm -
1 stop19h 48m
Wed 9/29:52 pm -
1 stop19h 19m
Deal found 8/6![Frontier logo]()
$230
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:39 pm -
1 stop3h 46m
Sun 9/66:00 am -
1 stop4h 20m
Deal found 8/4![Delta logo]()
$246
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:54 am -
Nonstop1h 55m
Sun 9/611:00 am -
Nonstop1h 56m
Deal found 8/2![American Airlines logo]()
$226
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm -
1 stop23h 35m
Fri 9/119:32 am -
1 stop8h 02m
Deal found 8/4![Frontier logo]()
$221
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm -
1 stop23h 35m
Tue 9/810:47 am -
1 stop6h 44m
Deal found 8/4![Frontier logo]()
$239
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:39 pm -
1 stop22h 42m
Mon 9/149:32 am -
1 stop8h 02m
Deal found 8/3![Frontier logo]()
$190
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:35 pm -
Nonstop2h 00m
Mon 9/145:20 pm -
Nonstop2h 05m
Deal found 8/5![Southwest logo]()
$236
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:19 pm -
1 stop14h 16m
Sun 9/139:40 pm -
1 stop19h 54m
Deal found 8/4![Frontier logo]()
$242
One-way flights from St. Louis to South CarolinaSearch for one-way flight options from St. Louis to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from St. Louis to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:17 pm -
2 stops37h 21m
Deal found 8/5![Multiple Airlines logo]()
$91
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:02 pm -
1 stop19h 48m
Deal found 8/3![Frontier logo]()
$96
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:02 pm -
1 stop19h 48m
Deal found 8/6![Frontier logo]()
$97
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:19 pm -
1 stop24h 02m
Deal found 8/3![Frontier logo]()
$98
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:35 am -
Nonstop1h 55m
Deal found 8/6![American Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:29 pm -
2 stops41h 09m
Deal found 8/4![Multiple Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm -
2 stops37h 51m
Deal found 8/3![Multiple Airlines logo]()
$106
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:04 pm -
1 stop4h 17m
Deal found 8/3![Delta logo]()
$109
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:40 pm -
Nonstop2h 00m
Deal found 8/6![Southwest logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:17 pm -
2 stops41h 17m
Deal found 8/2![Frontier logo]()
$111
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:58 pm -
1 stop19h 28m
Deal found 8/3![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:35 am -
2 stops26h 47m
Deal found 8/4![Multiple Airlines logo]()
$116
Find flight deals from St. Louis to South Carolina
Keep the following information in mind while searching for St. Louis to South Carolina flight deals. Data was last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Trip.com) |
One-way from | $91 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $384 |
Good one-way deal | $444 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from St. Louis to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Wed 9/2
6:00 am-11:54 am
1 stop4h 54m
Charleston
Sun 9/6
7:13 am-11:56 am
1 stop5h 43m
$251
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Sat 8/29
1:40 pm-4:40 pm
Nonstop2h 00m
Charleston
Mon 8/31
6:35 am-10:10 am
1 stop4h 35m
$260
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Sat 10/24
6:05 am-11:20 am
1 stop4h 15m
Charleston
Wed 10/28
8:10 am-11:35 am
1 stop4h 25m
$260
Quickest round-trip
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Mon 9/21
3:35 pm-6:35 pm
Nonstop2h 00m
Charleston
Thu 9/24
7:15 pm-10:10 pm
1 stop3h 55m
$260
St. LouisCharlotte
STL Lambert-St Louis - CLT Charlotte Douglas
STLCLT
Lambert-St Louis
Fri 9/4
6:00 am-1:26 pm
1 stop6h 26m
Charlotte Douglas
Sun 9/6
7:40 am-11:56 am
1 stop5h 16m
$261
St. LouisCharleston
STL Lambert-St Louis - CHS Charleston
STLCHS
Lambert-St Louis
Tue 10/6
10:20 am-8:20 pm
2 stops9h 00m
Charleston
Wed 10/7
8:10 am-11:35 am
1 stop4h 25m
$266
St. LouisCharlotte
STL Lambert-St Louis - CLT Charlotte Douglas
STLCLT
Lambert-St Louis
Wed 9/9
10:45 am-9:30 pm
2 stops9h 45m
Charlotte Douglas
Thu 9/24
11:50 am-12:45 pm
Nonstop1h 55m
$270
St. LouisGreenville
STL Lambert-St Louis - GSP Greenville
STLGSP
Lambert-St Louis
Sat 9/5
11:15 am-7:00 pm
1 stop6h 45m
Greenville
Sun 9/6
4:00 pm-8:25 pm
1 stop5h 25m
$272
St. LouisCharlotte
STL Lambert-St Louis - CLT Charlotte Douglas
STLCLT
Lambert-St Louis
Thu 10/8
7:20 pm-11:59 pm
1 stop3h 39m
Charlotte Douglas
Mon 10/12
7:46 pm-11:54 pm
1 stop5h 08m
$275
St. LouisCharlotte
STL Lambert-St Louis - CLT Charlotte Douglas
STLCLT
Lambert-St Louis
Wed 10/7
10:14 am-4:10 pm
1 stop4h 56m
Charlotte Douglas
Mon 10/12
7:46 pm-11:54 pm
1 stop5h 08m
$275
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from St. Louis to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from St. Louis with our price prediction graph.
STL-CLT
STL-CHS
STL-CAE
STL-GSP
STL-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to South Carolina
STL-USSC
STL-CLT
STL-CHS
STL-CAE
STL-GSP
What is the cheapest month to book a flight from St. Louis to South Carolina?
Currently, October is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $348). Flying from St. Louis to South Carolina in July is currently the most expensive (average of $424). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SC?
Find hourly flight availability from St. Louis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2026.
When flying from St. Louis to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from St. Louis to South Carolina?
Airfare is below average for this route at the moment.
St. Louis to South Carolina flights typically cost between $256 and $424 in August.The cheapest round-trip price found within the last 5 days was $231 on Multiple Airlines (Aug 29-Sep 5).
How far ahead should I book a flight from St. Louis to South Carolina?
The price you pay for your flight from St. Louis to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 50 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 7, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from St. Louis to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
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Alternative routes for St. Louis to South Carolina
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Complete your trip
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St. Louis and South Carolina flights
Browse other St. Louis and South Carolina flight options. Last updated on August 7, 2026.
Popular flight searches
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St. Louis to South Carolina flights
Consider these flights traveling from St. Louis to South Carolina.
Top 4 airlines flying from St. Louis to South Carolina
Discover the top 4 airlines that operate flights from St. Louis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$163 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$195 | Average$427 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$256 | Average$458 | FlexibilityNo cancel fee | On-time63% |