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South Carolina

$62+ Cheap flights from St. Louis (STL) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
mar 23 — mar 301
dom 3/23
dom 3/30
1 adult, Economy
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Cheap flight deals from St. Louis to South Carolina

Keep the following information in mind while searching for St. Louis to South Carolina flight deals. Data was last updated março 18, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$156
(Mytrip)

One-way from

$62
(Cheapflightsfares)

Popular in

December

Cheapest in

October

Average price

$431

Good round-trip deal

$373 or less
Provider with most accurate pricing for Lambert-St Louis-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Myrtle Beach Intl flights.
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From Lambert-St Louis to South Carolina
Search Deals
One-way flight from Lambert-St Louis to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Lambert-St Louis to South Carolina.
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Find flight deals from St. Louis to South Carolina

Cheapest flights from St. Louis to South Carolina
Explore the most affordable flight options available from St. Louis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on março 18, 2025.

This Mytrip deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 4/136:10 pmSTL - CHS
1 stop14h 26mSpirit Airlines
qua 4/167:30 pmCHS - STL
1 stop22h 45mSpirit Airlines
Deal found 3/18$156
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 4/74:57 pmSTL - CLT
1 stop17h 21mFrontier
qua 4/96:36 pmCLT - STL
1 stop6h 10mFrontier
Deal found 3/17$172
This Cheapflightsfares deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 4/106:10 pmSTL - CLT
1 stop5h 17mSpirit Airlines
qui 4/1710:30 amCLT - STL
1 stop7h 45mSpirit Airlines
Deal found 3/17$183
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 5/66:10 pmSTL - CLT
1 stop5h 17mMultiple Airlines
dom 5/1110:36 pmCLT - STL
1 stop26h 30mMultiple Airlines
Deal found 3/16$206
This Mytrip deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 5/212:15 pmSTL - MYR
3 stops34h 44mMultiple Airlines
qua 5/75:45 amMYR - STL
1 stop28h 30mMultiple Airlines
Deal found 3/16$226
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 4/106:10 pmSTL - MYR
1 stop15h 53mSpirit Airlines
dom 4/1312:08 pmMYR - STL
1 stop6h 07mSpirit Airlines
Deal found 3/17$232
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 8/303:30 pmSTL - CAE
1 stop3h 57mDelta
dom 8/3111:55 amCAE - STL
1 stop3h 40mDelta
Deal found 3/17$243
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 6/37:10 amSTL - HHH
1 stop4h 10mAmerican Airlines
ter 6/1011:03 amHHH - STL
1 stop6h 12mAmerican Airlines
Deal found 3/17$249
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 4/79:50 amSTL - CHS
3 stops26h 29mMultiple Airlines
qui 4/1010:25 amCHS - STL
1 stop7h 50mMultiple Airlines
Deal found 3/17$252
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 3/317:29 amSTL - CAE
1 stop7h 58mAmerican Airlines
qui 5/156:10 amCAE - STL
1 stop5h 33mAmerican Airlines
Deal found 3/17$254
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 4/77:19 amSTL - CLT
Nonstop1h 56mAmerican Airlines
qua 4/98:29 pmCLT - STL
Nonstop1h 55mAmerican Airlines
Deal found 3/17$277
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/152:20 pmSTL - CHS
Nonstop2h 00mSouthwest
ter 4/225:55 pmCHS - STL
Nonstop2h 20mSouthwest
Deal found 3/17$277

Find flights from St. Louis to South Carolina within your budget

Customize your flight search to find flights from St. Louis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated março 18, 2025.

Fly from

St. Louis

Fly to

South Carolina

Route

Depart

Return

Price

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

dom 4/13

6:10 pm-9:36 am

1 stop14h 26m

Charleston

qua 4/16

7:30 pm-5:15 pm

1 stop22h 45m

$156

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

seg 4/7

4:57 pm-11:18 am

1 stop17h 21m

Charlotte Douglas

qua 4/9

6:36 pm-11:46 pm

1 stop6h 10m

$172

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

qui 4/10

6:10 pm-12:27 am

1 stop5h 17m

Charlotte Douglas

qui 4/17

10:30 am-5:15 pm

1 stop7h 45m

$183

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

ter 5/6

6:10 pm-12:27 am

1 stop5h 17m

Charlotte Douglas

dom 5/11

10:36 pm-12:06 am

1 stop26h 30m

$206

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

sex 5/2

12:15 pm-11:59 pm

3 stops34h 44m

Myrtle Beach Intl

qua 5/7

5:45 am-9:15 am

1 stop28h 30m

$226

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

qui 4/10

6:10 pm-11:03 am

1 stop15h 53m

Myrtle Beach Intl

dom 4/13

12:08 pm-5:15 pm

1 stop6h 07m

$232

St. LouisColumbia

STL - CAE

STLCAE

Lambert-St Louis

sáb 8/30

3:30 pm-8:27 pm

1 stop3h 57m

Columbia Metropolitan

dom 8/31

11:55 am-2:35 pm

1 stop3h 40m

$243

St. LouisHilton Head Island

STL - HHH

STLHHH

Lambert-St Louis

ter 6/3

7:10 am-12:20 pm

1 stop4h 10m

Hilton Head Island

ter 6/10

11:03 am-4:15 pm

1 stop6h 12m

$249

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

seg 4/7

9:50 am-1:19 pm

3 stops26h 29m

Charleston

qui 4/10

10:25 am-5:15 pm

1 stop7h 50m

$252

St. LouisColumbia

STL - CAE

STLCAE

Lambert-St Louis

seg 3/31

7:29 am-4:27 pm

1 stop7h 58m

Columbia Metropolitan

qui 5/15

6:10 am-10:43 am

1 stop5h 33m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 60 results
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2
3
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Best time to book a flight from St. Louis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from St. Louis to South Carolina

Get recent, data-driven insights about flights from St. Louis to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from St. Louis to South Carolina?

Currently, August is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $217). Flying from St. Louis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SC?

Find hourly flight availability from St. Louis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated março 18, 2025.

When flying from St. Louis to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated março 18, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from St. Louis to South Carolina. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,280 reviews

Boarding

8.2

Crew

8.7

Food

7.1

Overall

8.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,280 reviews
Southwest
8.1
Very good
4,280 reviews

Boarding

8.2

Crew

8.7

Food

7.1

Overall

8.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,908 reviews
Southwest
8.1
Very good
4,280 reviews

Boarding

8.2

Crew

8.7

Food

7.1

Overall

8.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,611 reviews
Southwest
8.1
Very good
4,280 reviews

Boarding

8.2

Crew

8.7

Food

7.1

Overall

8.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,280 reviews

Boarding

8.2

Crew

8.7

Food

7.1

Overall

8.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Sun Country Air
6.9
Okay
349 reviews
Southwest
8.1
Very good
4,280 reviews

Boarding

8.2

Crew

8.7

Food

7.1

Overall

8.1

Comfort

8.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to South Carolina?

    For a flight from St. Louis to South Carolina, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How popular is this St. Louis to South Carolina flight route?

    Within the past month, 4 users have taken a look at flights from Lambert-St Louis to South Carolina.

  • What are the cheapest airlines to fly from St. Louis to South Carolina one-way?

    The cheapest airlines for a one-way flight from St. Louis to South Carolina are Spirit Airlines ($62), Frontier ($96), and Sun Country Air ($123).

  • What are the most popular routes from St. Louis to South Carolina?

    While some choose either Lambert-St Louis - Charleston or Lambert-St Louis - Savannah/Hilton Head, Lambert-St Louis - Charlotte Douglas is the most popular route from St. Louis to South Carolina.

  • What are the cheapest flights from St. Louis to South Carolina?

    Looking for the cheapest flight from St. Louis to South Carolina? While on average our users pay $408, our data indicates the cheapest price to be $307. The most popular route (Lambert-St Louis - Charlotte Douglas), is priced around $183.

  • Can I find deals for flights from St. Louis to South Carolina that include hotel bookings?

    Yes. In addition to deals on St. Louis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to South Carolina.

  • Can I find deals for business class flights from St. Louis to South Carolina?

    Yes. Cheapflights offers flight deals from St. Louis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $217). Flying from St. Louis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for St. Louis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from St. Louis to South Carolina

Discover the top 5 airlines that operate flights from St. Louis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated março 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$166Average$199FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$188Average$380FlexibilityNo cancel feeOn-time71%
DeltaCheapest$227Average$390FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$306Average$411FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$465Average$640FlexibilityNo cancel feeOn-time69%
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