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St. Louis

$72+ Cheap flights from South Carolina to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
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Cheap flight deals from South Carolina to St. Louis

Keep the following information in mind while searching for South Carolina to St. Louis flight deals. Data was last updated July 2, 2025.

Round-trip from

$135
(Mytrip)

One-way from

$72
(Priceline)

Popular in

February

Cheapest in

June

Average price

$333

Good round-trip deal

$287 or less

Good one-way deal

$238 or less
From South Carolina to Lambert-St Louis
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One-way flight from South Carolina to Lambert-St Louis
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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from South Carolina to Lambert-St Louis.
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Price to beat on a one-way flight from South Carolina to Lambert-St Louis.
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Find flight deals from South Carolina to St. Louis

Cheapest flights from South Carolina to St. Louis
Explore the most affordable flight options available from South Carolina to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/167:03 pmCLT - STL
1 stop5h 44mFrontier
Sat 8/237:54 pmSTL - CLT
1 stop19h 43mFrontier
Deal found 7/2$135
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/227:03 pmCLT - STL
1 stop5h 44mMultiple Airlines
Thu 7/2410:47 amSTL - CLT
1 stop5h 37mMultiple Airlines
Deal found 6/30$146
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/26:00 amCLT - STL
1 stop9h 39mSpirit Airlines
Mon 8/1110:47 amSTL - CLT
1 stop5h 30mSpirit Airlines
Deal found 6/30$179
This Booking.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/37:20 amMYR - STL
1 stop10h 11mSpirit Airlines
Fri 8/810:47 amSTL - MYR
1 stop10h 51mSpirit Airlines
Deal found 7/1$184
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/77:50 pmCLT - STL
Nonstop2h 00mSouthwest
Mon 8/112:45 pmSTL - CLT
Nonstop1h 50mSouthwest
Deal found 6/30$197
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/37:50 pmMYR - STL
1 stop5h 03mDelta
Thu 8/77:11 pmSTL - MYR
1 stop3h 48mDelta
Deal found 7/1$197
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:23 pmCHS - STL
1 stop6h 30mDelta
Thu 8/146:49 pmSTL - CHS
1 stop4h 02mDelta
Deal found 6/30$207
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3011:00 amCAE - STL
1 stop4h 36mDelta
Tue 8/53:16 pmSTL - CAE
1 stop7h 25mDelta
Deal found 6/30$217
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:45 pmCHS - STL
1 stop4h 20mSouthwest
Mon 8/257:50 amSTL - CHS
Nonstop1h 55mSouthwest
Deal found 7/1$221
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/48:25 amCLT - STL
1 stop5h 01mDelta
Sat 9/65:25 pmSTL - CLT
1 stop4h 56mDelta
Deal found 7/2$227
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:36 pmCLT - STL
1 stop7h 56mAmerican Airlines
Sat 9/62:11 pmSTL - CLT
Nonstop2h 00mAmerican Airlines
Deal found 6/30$230
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2910:41 amCAE - STL
1 stop7h 06mAmerican Airlines
Tue 8/55:48 pmSTL - CAE
1 stop4h 56mAmerican Airlines
Deal found 6/30$230

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from South Carolina to St. Louis that are best for you.

Fly from

South Carolina

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/16

7:03 pm-11:47 pm

1 stop5h 44m

Lambert-St Louis

Sat 8/23

7:54 pm-4:37 pm

1 stop19h 43m

$135

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 7/22

7:03 pm-11:47 pm

1 stop5h 44m

Lambert-St Louis

Thu 7/24

10:47 am-5:24 pm

1 stop5h 37m

$146

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/2

6:00 am-2:39 pm

1 stop9h 39m

Lambert-St Louis

Mon 8/11

10:47 am-5:17 pm

1 stop5h 30m

$179

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sun 8/3

7:20 am-4:31 pm

1 stop10h 11m

Lambert-St Louis

Fri 8/8

10:47 am-10:38 pm

1 stop10h 51m

$184

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 8/7

7:50 pm-8:50 pm

Nonstop2h 00m

Lambert-St Louis

Mon 8/11

2:45 pm-5:35 pm

Nonstop1h 50m

$197

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sun 8/3

7:50 pm-11:53 pm

1 stop5h 03m

Lambert-St Louis

Thu 8/7

7:11 pm-11:59 pm

1 stop3h 48m

$197

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 8/7

7:59 pm-11:53 pm

1 stop4h 54m

Lambert-St Louis

Thu 8/14

6:00 am-2:23 pm

1 stop7h 23m

$207

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 7/30

11:00 am-2:36 pm

1 stop4h 36m

Lambert-St Louis

Tue 8/5

3:16 pm-11:41 pm

1 stop7h 25m

$217

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 8/20

6:45 pm-10:05 pm

1 stop4h 20m

Lambert-St Louis

Mon 8/25

7:50 am-10:45 am

Nonstop1h 55m

$221

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 9/4

8:25 am-12:26 pm

1 stop5h 01m

Lambert-St Louis

Sat 9/6

5:25 pm-11:21 pm

1 stop4h 56m

$227

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to St. Louis

What is the cheapest month to book a flight from South Carolina to St. Louis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to St. Louis (average of $311). Flying from South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to STL?

Find hourly flight availability from South Carolina to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

When flying from South Carolina to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 2, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from South Carolina to St. Louis have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,272 reviews

Entertainment

7.6

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,272 reviews
Southwest
8.0
Very good
4,272 reviews

Entertainment

7.6

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,983 reviews
Southwest
8.0
Very good
4,272 reviews

Entertainment

7.6

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,272 reviews

Entertainment

7.6

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,272 reviews

Entertainment

7.6

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Spirit Airlines
6.3
Okay
8,103 reviews
Southwest
8.0
Very good
4,272 reviews

Entertainment

7.6

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from South Carolina?

    For a flight from South Carolina to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How popular is this South Carolina to St. Louis flight route?

    Within the past month, 6 users have taken a look at flights from South Carolina to Lambert-St Louis.

  • What are the cheapest airlines to fly from South Carolina to St. Louis one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $72. Spirit Airlines flights start at $85 while deals on Southwest start at $89 one-way.

  • What are the most popular routes from South Carolina to St. Louis?

    The most popular flight routes from South Carolina to St. Louis are Charlotte Douglas - Lambert-St Louis, Charleston - Lambert-St Louis and Savannah/Hilton Head - Lambert-St Louis.

  • What are the cheapest flights from South Carolina to St. Louis?

    On average you can expect to pay $302 for a flight from South Carolina to St. Louis. The cheapest flight overall is $218 while the most popular route, (Charlotte Douglas - Lambert-St Louis) is currently priced at $191.

  • Can I find deals for flights from South Carolina to St. Louis that include hotel bookings?

    Yes. In addition to deals on South Carolina to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to St. Louis.

  • Can I find deals for business class flights from South Carolina to St. Louis?

    Yes. Cheapflights offers flight deals from South Carolina to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to St. Louis (average of $311). Flying from South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Festus
Chesterfield
Farmington

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Alternative routes for South Carolina to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to St. Louis

Discover the top 3 airlines that operate flights from South Carolina to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$172Average$365FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$362FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$286Average$362FlexibilityNo cancel feeOn-time63%

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