$149+ Cheap flights from Missouri to South Dakota
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — FSD
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to South Dakota with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to South DakotaExplore the most affordable flight options available from Missouri to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Missouri to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 pm -
1 stop4h 14m
Tue 11/177:18 pm -
1 stop4h 41m
Deal found 10/21![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:26 am -
1 stop7h 27m
Sun 11/157:18 pm -
1 stop4h 37m
Deal found 10/23![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:15 am -
1 stop5h 04m
Tue 12/295:00 am -
1 stop5h 35m
Deal found 10/22![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:45 am -
1 stop4h 46m
Sat 12/54:31 pm -
1 stop6h 13m
Deal found 10/23![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:40 pm -
1 stop6h 39m
Fri 11/278:30 am -
1 stop7h 27m
Deal found 10/21![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:40 pm -
1 stop4h 49m
Sun 11/227:48 am -
1 stop6h 45m
Deal found 10/21![United Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:44 am -
1 stop6h 55m
Sat 12/51:09 pm -
2 stops10h 27m
Deal found 10/23![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:25 pm -
1 stop5h 04m
Mon 11/97:18 pm -
1 stop5h 06m
Deal found 10/21![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:58 pm -
1 stop7h 56m
Sun 11/87:18 pm -
1 stop4h 37m
Deal found 10/20![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:20 pm -
1 stop6h 09m
Tue 11/245:00 am -
1 stop4h 50m
Deal found 10/20![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
1 stop4h 23m
Mon 11/306:08 pm -
1 stop4h 39m
Deal found 10/22![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop5h 31m
Sat 11/145:00 am -
1 stop6h 38m
Deal found 10/24![United Airlines logo]()
$354
Best flights from Missouri to South DakotaDiscover carefully curated flight deals from Missouri to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Missouri to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/76:00 am -
1 stop6h 35m
Sun 4/116:00 am -
1 stop4h 33m
Deal found 10/22![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 pm -
1 stop4h 14m
Tue 11/177:18 pm -
1 stop4h 41m
Deal found 10/21![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:22 pm -
1 stop5h 38m
Mon 12/75:02 pm -
1 stop6h 24m
Deal found 10/23![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:40 pm -
1 stop6h 24m
Mon 11/237:39 am -
1 stop4h 31m
Deal found 10/23![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:26 am -
1 stop7h 27m
Sun 11/157:18 pm -
1 stop4h 37m
Deal found 10/23![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:15 am -
1 stop5h 04m
Tue 12/295:00 am -
1 stop5h 35m
Deal found 10/22![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/15:40 pm -
1 stop5h 59m
Mon 2/86:55 am -
1 stop6h 46m
Deal found 10/20![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:01 am -
1 stop5h 38m
Mon 12/141:09 pm -
1 stop5h 45m
Deal found 10/22![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:40 am -
1 stop5h 23m
Sun 12/67:00 am -
1 stop4h 53m
Deal found 10/24![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:40 pm -
1 stop6h 39m
Fri 11/278:30 am -
1 stop7h 27m
Deal found 10/21![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:16 pm -
1 stop5h 41m
Sat 1/210:52 am -
1 stop5h 44m
Deal found 10/20![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:40 pm -
1 stop4h 49m
Sun 11/227:48 am -
1 stop6h 45m
Deal found 10/21![United Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/308:22 pm -
1 stop4h 24m
Sat 1/27:27 pm -
1 stop4h 53m
Deal found 10/22![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
1 stop4h 23m
Mon 11/306:08 pm -
1 stop4h 39m
Deal found 10/22![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:15 am -
1 stop5h 04m
Mon 12/2810:52 am -
1 stop3h 52m
Deal found 10/22![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop5h 31m
Sat 11/145:00 am -
1 stop6h 38m
Deal found 10/24![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:40 pm -
1 stop6h 39m
Sun 11/151:30 pm -
1 stop7h 10m
Deal found 10/24![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/76:00 am -
2 stops9h 50m
Sun 4/118:15 am -
1 stop3h 33m
Deal found 10/22![Delta logo]()
$477
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:39 pm -
1 stop7h 05m
Sun 11/87:48 am -
1 stop4h 22m
Deal found 10/25![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:39 pm -
1 stop5h 04m
Sat 11/285:50 pm -
1 stop4h 49m
Deal found 10/22![United Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/278:50 am -
1 stop7h 30m
Sat 1/305:13 pm -
1 stop6h 31m
Deal found 10/20![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/48:28 am -
1 stop5h 14m
Wed 3/241:12 pm -
1 stop6h 47m
Deal found 10/21![American Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/69:00 am -
1 stop7h 20m
Sat 1/99:25 am -
1 stop6h 59m
Deal found 10/22![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:45 pm -
1 stop6h 19m
Mon 11/95:55 am -
1 stop6h 33m
Deal found 10/21![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:05 pm -
1 stop6h 29m
Sat 1/92:40 pm -
1 stop5h 15m
Deal found 10/24![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/271:38 pm -
1 stop6h 23m
Sat 1/306:00 am -
1 stop7h 17m
Deal found 10/24![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:45 am -
1 stop4h 48m
Mon 11/306:08 pm -
1 stop4h 39m
Deal found 10/20![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/273:10 pm -
1 stop6h 20m
Sat 1/3012:50 pm -
1 stop6h 48m
Deal found 10/20![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:45 am -
1 stop4h 35m
Mon 11/95:08 pm -
1 stop6h 44m
Deal found 10/21![United Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:13 pm -
1 stop27h 02m
Fri 1/19:00 am -
1 stop7h 07m
Deal found 10/21![United Airlines logo]()
$580
Last-minute flights from Missouri to South DakotaDiscover last-minute flight deals from Missouri to South Dakota. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to South Dakota. Data last updated October 25, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:39 pm -
1 stop7h 05m
Wed 11/46:00 am -
1 stop4h 32m
Deal found 10/21![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:58 pm -
1 stop7h 56m
Sun 11/87:18 pm -
1 stop4h 37m
Deal found 10/20![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:25 pm -
1 stop5h 04m
Mon 11/97:18 pm -
1 stop5h 06m
Deal found 10/21![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:26 am -
1 stop7h 27m
Sun 11/157:18 pm -
1 stop4h 37m
Deal found 10/23![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:39 pm -
1 stop7h 05m
Sun 11/87:48 am -
1 stop4h 22m
Deal found 10/24![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 pm -
1 stop4h 14m
Tue 11/177:18 pm -
1 stop4h 41m
Deal found 10/21![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop5h 31m
Sat 11/145:00 am -
1 stop6h 38m
Deal found 10/24![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:40 pm -
1 stop6h 39m
Sun 11/151:30 pm -
1 stop7h 10m
Deal found 10/24![United Airlines logo]()
$368
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:20 pm -
1 stop6h 09m
Tue 11/245:00 am -
1 stop4h 50m
Deal found 10/20![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:40 pm -
1 stop4h 49m
Sun 11/227:48 am -
1 stop6h 45m
Deal found 10/21![United Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:40 pm -
1 stop6h 39m
Fri 11/278:30 am -
1 stop7h 27m
Deal found 10/21![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
1 stop4h 23m
Mon 11/306:08 pm -
1 stop4h 39m
Deal found 10/22![United Airlines logo]()
$354
One-way flights from Missouri to South DakotaSearch for one-way flight options from Missouri to South Dakota. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Missouri to South Dakota. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:00 pm -
2 stops18h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:44 pm -
1 stop19h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:10 pm -
2 stops29h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:15 pm -
1 stop15h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Allegiant Air logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:43 pm -
2 stops18h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:00 pm -
2 stops18h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:59 pm -
2 stops15h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:59 pm -
2 stops17h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:59 pm -
2 stops17h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:49 pm -
1 stop4h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:29 pm -
3 stops21h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:26 am -
1 stop4h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$333
Find flight deals from Missouri to South Dakota
Keep the following information in mind while searching for Missouri to South Dakota flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (United Airlines) |
One-way from | $149 (Kiwi.com) |
Popular in | July |
Cheapest in | December |
Average price | $422 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Missouri to South Dakota that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Thu 11/5
2:00 pm-8:38 am
2 stops18h 38m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$149
Kansas CityRapid City
MCI Kansas City - RAP Rapid City
MCIRAP
Kansas City
Mon 11/23
2:44 pm-9:12 am
1 stop19h 28m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$165
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Thu 10/29
2:10 pm-7:19 pm
2 stops29h 09m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$184
Kansas CityRapid City
MCI Kansas City - RAP Rapid City
MCIRAP
Kansas City
Wed 11/4
8:43 pm-2:06 pm
2 stops18h 23m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$219
Kansas CitySioux Falls
MCI Kansas City - FSD Sioux Falls Joe Foss Field
MCIFSD
Kansas City
Wed 4/7
6:00 am-12:35 pm
1 stop6h 35m
Sioux Falls Joe Foss Field
Sun 4/11
6:00 am-10:33 am
1 stop4h 33m
$319
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Thu 11/12
8:15 pm-12:29 am
1 stop4h 14m
Sioux Falls Joe Foss Field
Tue 11/17
7:18 pm-11:59 pm
1 stop4h 41m
$319
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Mon 11/30
5:22 pm-11:00 pm
1 stop5h 38m
Sioux Falls Joe Foss Field
Mon 12/7
5:02 pm-11:26 pm
1 stop6h 24m
$319
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Fri 11/20
1:40 pm-8:04 pm
1 stop6h 24m
Sioux Falls Joe Foss Field
Mon 11/23
7:39 am-12:10 pm
1 stop4h 31m
$319
St. LouisRapid City
STL Lambert-St Louis - RAP Rapid City
STLRAP
Lambert-St Louis
Sat 10/31
7:59 pm-12:39 pm
2 stops17h 40m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$322
Kansas CitySioux Falls
MCI Kansas City - FSD Sioux Falls Joe Foss Field
MCIFSD
Kansas City
Sun 11/22
8:29 pm-5:48 pm
3 stops21h 19m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from Missouri to South Dakota
Have a flexible travel schedule? Discover the best time to fly to South Dakota from Missouri with our price prediction graph.
STL-FSD
STL-RAP
SGF-FSD
MCI-FSD
MCI-RAP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to South Dakota
USMO-USSD
STL-FSD
STL-RAP
SGF-FSD
MCI-FSD
What is the cheapest month to book a flight from Missouri to South Dakota?
Currently, January is the cheapest month in which you can book a flight from Missouri to South Dakota (average of $339). Flying from Missouri to South Dakota in October is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to South Dakota?
Airfare is below average for this route at the moment.
Missouri to South Dakota flights typically cost between $402 and $526 in November.The cheapest round-trip price found within the last 5 days was $319 on American Airlines (Nov 12-Nov 17).
Reviews of airlines servicing South Dakota
Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated October 25, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Missouri to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Missouri to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to South Dakota
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Dakota by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to South Dakota by cabin class
Find flights from Missouri to South Dakota, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and South Dakota flights
Browse other Missouri and South Dakota flight options. Last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Dakota
Find the right flight back to Missouri after your stay in South Dakota
Missouri to South Dakota flights
Consider these flights traveling from Missouri to South Dakota.
Top 3 airlines flying from Missouri to South Dakota
Discover the top 3 airlines that operate flights from Missouri to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$399 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$437 | FlexibilityNo cancel fee | On-time69% |