$146+ Cheap flights from Missouri to South Dakota
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — FSD
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to South Dakota with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to South DakotaExplore the most affordable flight options available from Missouri to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Missouri to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:32 am -
1 stop5h 41m
Fri 10/235:54 pm -
1 stop5h 48m
Deal found 9/8![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:25 am -
1 stop6h 48m
Sun 10/117:39 pm -
1 stop4h 49m
Deal found 9/8![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:18 pm -
1 stop7h 11m
Sun 9/276:41 pm -
1 stop5h 46m
Deal found 9/4![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:27 pm -
1 stop7h 56m
Sat 10/34:56 pm -
1 stop5h 28m
Deal found 9/3![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:14 am -
1 stop7h 06m
Wed 9/2312:56 pm -
1 stop6h 11m
Deal found 9/4![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop6h 36m
Tue 10/67:39 pm -
1 stop4h 40m
Deal found 9/5![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:43 am -
1 stop5h 04m
Wed 9/304:56 pm -
1 stop5h 47m
Deal found 9/3![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
1 stop4h 48m
Sun 11/85:50 pm -
1 stop5h 02m
Deal found 9/6![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop5h 14m
Wed 10/145:04 pm -
1 stop5h 38m
Deal found 9/7![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:13 pm -
1 stop6h 20m
Tue 9/225:48 pm -
1 stop4h 42m
Deal found 9/3![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:16 pm -
1 stop6h 21m
Tue 11/31:20 pm -
1 stop7h 27m
Deal found 9/3![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:40 pm -
1 stop7h 04m
Mon 9/146:41 pm -
1 stop4h 18m
Deal found 9/4![United Airlines logo]()
$369
Best flights from Missouri to South DakotaDiscover carefully curated flight deals from Missouri to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Missouri to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:43 am -
1 stop5h 04m
Wed 9/304:56 pm -
1 stop5h 47m
Deal found 9/4![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:38 pm -
1 stop6h 08m
Mon 12/146:42 am -
1 stop7h 07m
Deal found 9/7![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
1 stop4h 48m
Sun 11/85:50 pm -
1 stop5h 02m
Deal found 9/6![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:35 pm -
2 stops23h 31m
Sun 10/257:34 pm -
1 stop27h 39m
Deal found 9/8![Multiple Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:13 pm -
1 stop6h 20m
Tue 9/225:48 pm -
1 stop4h 42m
Deal found 9/3![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:32 am -
1 stop5h 41m
Sat 10/2412:53 pm -
1 stop6h 55m
Deal found 9/7![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:16 pm -
1 stop6h 21m
Tue 11/31:20 pm -
1 stop7h 27m
Deal found 9/3![United Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:36 pm -
2 stops15h 41m
Mon 12/1411:07 am -
1 stop8h 59m
Deal found 9/7![Multiple Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:30 am -
1 stop3h 30m
Fri 10/238:30 am -
1 stop3h 23m
Deal found 9/8![Delta logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:21 am -
2 stops9h 59m
Tue 10/65:54 pm -
1 stop5h 48m
Deal found 9/5![American Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:40 pm -
1 stop6h 24m
Mon 11/21:20 pm -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:08 pm -
1 stop4h 33m
Fri 10/2312:53 pm -
1 stop7h 14m
Deal found 9/8![American Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:00 pm -
2 stops29h 14m
Sun 10/257:34 pm -
1 stop27h 39m
Deal found 9/8![Multiple Airlines logo]()
$455
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:30 am -
1 stop3h 47m
Sat 1/25:10 pm -
1 stop4h 37m
Deal found 9/6![Delta logo]()
$456
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:13 pm -
1 stop7h 10m
Sat 1/910:00 am -
1 stop4h 34m
Deal found 9/4![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:51 pm -
1 stop4h 38m
Wed 9/2312:56 pm -
1 stop7h 22m
Deal found 9/4![American Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:10 pm -
2 stops8h 53m
Sat 10/175:00 pm -
1 stop5h 20m
Deal found 9/8![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:10 am -
1 stop7h 45m
Sat 10/247:05 am -
1 stop4h 35m
Deal found 9/3![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/308:22 pm -
1 stop4h 24m
Sat 1/27:35 pm -
1 stop4h 24m
Deal found 9/7![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 pm -
1 stop4h 46m
Tue 10/279:32 am -
1 stop6h 49m
Deal found 9/7![United Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:13 pm -
1 stop7h 57m
Sat 1/92:40 pm -
1 stop4h 54m
Deal found 9/7![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:30 am -
1 stop3h 30m
Tue 10/135:10 am -
2 stops8h 15m
Deal found 9/4![Delta logo]()
$607
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:22 am -
2 stops12h 08m
Sat 10/105:53 pm -
1 stop4h 22m
Deal found 9/6![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:00 am -
2 stops12h 25m
Sun 10/185:04 pm -
1 stop5h 38m
Deal found 9/6![American Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:34 pm -
1 stop6h 45m
Sat 11/75:50 pm -
1 stop5h 02m
Deal found 9/3![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:43 pm -
1 stop5h 10m
Wed 9/237:00 am -
1 stop4h 37m
Deal found 9/3![United Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:35 pm -
1 stop4h 54m
Fri 9/256:41 pm -
1 stop5h 42m
Deal found 9/6![American Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:24 pm -
1 stop6h 20m
Tue 10/67:50 am -
1 stop4h 30m
Deal found 9/4![United Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:20 pm -
2 stops11h 10m
Wed 10/145:00 am -
2 stops9h 21m
Deal found 9/7![United Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:30 am -
1 stop5h 14m
Thu 9/246:50 pm -
1 stop4h 52m
Deal found 9/5![United Airlines logo]()
$665
Last-minute flights from Missouri to South DakotaDiscover last-minute flight deals from Missouri to South Dakota. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to South Dakota. Data last updated September 8, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:40 pm -
1 stop7h 04m
Mon 9/146:41 pm -
1 stop4h 18m
Deal found 9/4![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:01 am -
2 stops9h 44m
Mon 9/145:59 pm -
1 stop5h 44m
Deal found 9/4![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:13 pm -
1 stop6h 20m
Tue 9/225:48 pm -
1 stop4h 42m
Deal found 9/3![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:14 am -
1 stop7h 06m
Wed 9/2312:56 pm -
1 stop6h 11m
Deal found 9/4![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:43 am -
1 stop5h 04m
Wed 9/304:56 pm -
1 stop5h 47m
Deal found 9/3![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:18 pm -
1 stop7h 11m
Sun 9/276:41 pm -
1 stop5h 46m
Deal found 9/4![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:27 pm -
1 stop7h 56m
Sat 10/34:56 pm -
1 stop5h 28m
Deal found 9/3![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop6h 36m
Tue 10/67:39 pm -
1 stop4h 40m
Deal found 9/5![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop5h 14m
Wed 10/145:04 pm -
1 stop5h 38m
Deal found 9/7![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:25 am -
1 stop6h 48m
Sun 10/117:39 pm -
1 stop4h 49m
Deal found 9/8![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:32 am -
1 stop5h 41m
Fri 10/235:54 pm -
1 stop5h 48m
Deal found 9/8![American Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:16 pm -
1 stop6h 21m
Tue 11/31:20 pm -
1 stop7h 27m
Deal found 9/3![United Airlines logo]()
$369
One-way flights from Missouri to South DakotaSearch for one-way flight options from Missouri to South Dakota. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Missouri to South Dakota. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:32 pm -
1 stop23h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:30 pm -
2 stops38h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$246
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:18 pm -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:01 am -
2 stops9h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am -
1 stop4h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:25 am -
1 stop5h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop5h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:29 pm -
3 stops24h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:29 pm -
2 stops8h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:18 pm -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:53 pm -
3 stops46h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:43 pm -
1 stop4h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$374
Find flight deals from Missouri to South Dakota
Keep the following information in mind while searching for Missouri to South Dakota flight deals. Data was last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $290 (American Airlines) |
One-way from | $139 (Trip.com) |
Popular in | July |
Cheapest in | September |
Average price | $297 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Missouri to South Dakota that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CitySioux Falls
MCI Kansas City - FSD Sioux Falls Joe Foss Field
MCIFSD
Kansas City
Thu 9/17
8:32 pm-8:07 pm
1 stop23h 35m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
Kansas CityRapid City
MCI Kansas City - RAP Rapid City
MCIRAP
Kansas City
Mon 9/14
10:30 pm-12:15 pm
2 stops38h 45m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$246
Quickest round-trip
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Sat 9/26
10:27 am-2:28 pm
1 stop4h 01m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Fri 9/25
5:18 pm-12:29 am
1 stop7h 11m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Sat 9/26
11:01 am-8:45 pm
2 stops9h 44m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$269
SpringfieldRapid City
SGF Springfield-Branson - RAP Rapid City
SGFRAP
Springfield-Branson
Mon 9/28
6:00 am-9:47 am
1 stop4h 47m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
Kansas CityRapid City
MCI Kansas City - RAP Rapid City
MCIRAP
Kansas City
Mon 10/12
5:25 am-9:54 am
1 stop5h 29m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
St. LouisRapid City
STL Lambert-St Louis - RAP Rapid City
STLRAP
Lambert-St Louis
Thu 10/8
5:40 am-9:54 am
1 stop5h 14m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
St. LouisRapid City
STL Lambert-St Louis - RAP Rapid City
STLRAP
Lambert-St Louis
Wed 10/7
2:29 pm-1:45 pm
3 stops24h 16m
Rapid City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
St. LouisSioux Falls
STL Lambert-St Louis - FSD Sioux Falls Joe Foss Field
STLFSD
Lambert-St Louis
Mon 9/21
5:18 pm-12:29 am
1 stop7h 11m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$323
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from Missouri to South Dakota
Have a flexible travel schedule? Discover the best time to fly to South Dakota from Missouri with our price prediction graph.
MCI-FSD
MCI-RAP
STL-FSD
SGF-RAP
STL-RAP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to South Dakota
USMO-USSD
MCI-FSD
MCI-RAP
STL-FSD
SGF-RAP
What is the cheapest month to book a flight from Missouri to South Dakota?
Currently, November is the cheapest month in which you can book a flight from Missouri to South Dakota (average of $328). Flying from Missouri to South Dakota in August is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to South Dakota?
Airfare is below average for this route at the moment.
Missouri to South Dakota flights typically cost between $297 and $417 in October.The cheapest round-trip price found within the last 5 days was $290 on American Airlines (Oct 14-Oct 23).
Reviews of airlines servicing South Dakota
Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated September 8, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Missouri to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Missouri to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to South Dakota
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Dakota by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to South Dakota by cabin class
Find flights from Missouri to South Dakota, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and South Dakota flights
Browse other Missouri and South Dakota flight options. Last updated on September 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Dakota
Find the right flight back to Missouri after your stay in South Dakota
Missouri to South Dakota flights
Consider these flights traveling from Missouri to South Dakota.
Top 3 airlines flying from Missouri to South Dakota
Discover the top 3 airlines that operate flights from Missouri to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$372 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$258 | Average$415 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$293 | Average$411 | FlexibilityNo cancel fee | On-time71% |