$140+ Cheap flights from South Dakota to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Nov 26 — Dec 31
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Dakota to MissouriExplore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 pm -
1 stop6h 22m
Sun 11/2212:28 pm -
1 stop6h 38m
Deal found 10/24![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:00 am -
1 stop5h 03m
Fri 1/16:00 am -
1 stop5h 58m
Deal found 10/24![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:58 pm -
1 stop5h 35m
Mon 11/168:15 pm -
1 stop4h 14m
Deal found 10/24![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:22 am -
1 stop4h 49m
Sun 11/155:45 am -
1 stop6h 50m
Deal found 10/25![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:50 pm -
1 stop5h 02m
Fri 11/276:00 am -
1 stop5h 31m
Deal found 10/25![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:37 pm -
1 stop5h 51m
Wed 1/65:30 pm -
1 stop6h 09m
Deal found 10/23![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:40 pm -
1 stop4h 44m
Wed 11/114:39 pm -
1 stop7h 05m
Deal found 10/22![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:55 am -
1 stop4h 55m
Sat 11/148:45 am -
1 stop7h 40m
Deal found 10/26![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:36 pm -
1 stop5h 48m
Tue 11/1710:32 am -
1 stop6h 22m
Deal found 10/26![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:20 pm -
1 stop7h 21m
Wed 11/113:00 pm -
1 stop6h 37m
Deal found 10/23![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:08 pm -
1 stop7h 14m
Sun 11/156:00 am -
1 stop6h 28m
Deal found 10/25![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:30 am -
1 stop4h 41m
Mon 11/165:20 pm -
1 stop4h 23m
Deal found 10/27![United Airlines logo]()
$369
Best flights from South Dakota to MissouriDiscover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:31 am -
1 stop6h 10m
Mon 11/3012:28 pm -
1 stop6h 38m
Deal found 10/26![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:40 pm -
1 stop4h 44m
Wed 11/114:39 pm -
1 stop7h 05m
Deal found 10/22![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/276:07 pm -
1 stop5h 25m
Sat 1/3011:34 am -
2 stops9h 20m
Deal found 10/24![American Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:17 pm -
2 stops31h 18m
Sun 12/207:53 pm -
1 stop13h 56m
Deal found 10/25![Multiple Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:31 am -
1 stop6h 10m
Sun 11/296:13 am -
1 stop4h 07m
Deal found 10/26![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:55 am -
1 stop4h 55m
Sat 11/148:45 am -
1 stop7h 40m
Deal found 10/26![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:00 am -
1 stop5h 03m
Fri 1/16:00 am -
1 stop5h 58m
Deal found 10/24![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
1 stop4h 39m
Mon 11/165:45 am -
1 stop4h 48m
Deal found 10/26![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:09 pm -
1 stop7h 53m
Tue 11/179:12 am -
2 stops13h 15m
Deal found 10/22![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:37 pm -
1 stop5h 51m
Wed 1/66:05 am -
1 stop4h 57m
Deal found 10/24![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:20 pm -
1 stop7h 21m
Wed 11/113:00 pm -
1 stop6h 37m
Deal found 10/23![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:34 pm -
1 stop5h 05m
Sat 12/265:20 am -
1 stop6h 04m
Deal found 10/24![American Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:36 pm -
1 stop5h 48m
Tue 11/1710:32 am -
1 stop6h 22m
Deal found 10/26![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:39 pm -
1 stop7h 08m
Fri 11/276:00 am -
1 stop5h 31m
Deal found 10/22![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:39 pm -
1 stop7h 08m
Sat 11/141:34 pm -
1 stop6h 45m
Deal found 10/26![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/211:12 pm -
2 stops18h 17m
Wed 1/611:50 am -
2 stops9h 33m
Deal found 10/23![American Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/99:45 am -
1 stop6h 35m
Tue 1/121:17 pm -
1 stop5h 21m
Deal found 10/22![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:20 pm -
1 stop7h 41m
Wed 11/185:02 pm -
1 stop6h 42m
Deal found 10/24![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:58 am -
1 stop3h 43m
Thu 1/76:00 am -
2 stops9h 50m
Deal found 10/23![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop6h 30m
Mon 12/75:19 pm -
1 stop6h 25m
Deal found 10/26![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
1 stop7h 18m
Mon 1/113:18 pm -
1 stop7h 20m
Deal found 10/23![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:05 am -
2 stops8h 23m
Sat 11/1410:36 am -
2 stops8h 30m
Deal found 10/26![Delta logo]()
$609
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:00 am -
1 stop4h 54m
Wed 2/31:35 pm -
1 stop4h 43m
Deal found 10/23![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:00 am -
1 stop7h 28m
Tue 1/128:52 am -
1 stop5h 14m
Deal found 10/26![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:10 pm -
1 stop6h 41m
Wed 11/115:20 pm -
1 stop6h 24m
Deal found 10/23![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:15 am -
1 stop7h 45m
Tue 1/55:06 pm -
1 stop5h 32m
Deal found 10/24![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:13 pm -
1 stop6h 31m
Thu 1/76:00 am -
1 stop4h 44m
Deal found 10/23![United Airlines logo]()
$542
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:20 pm -
1 stop7h 27m
Tue 11/108:45 am -
1 stop7h 40m
Deal found 10/22![United Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:13 pm -
1 stop6h 31m
Sun 1/101:38 pm -
1 stop6h 59m
Deal found 10/26![United Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:22 am -
2 stops12h 02m
Mon 11/306:50 pm -
1 stop4h 42m
Deal found 10/26![United Airlines logo]()
$636
Last-minute flights from South Dakota to MissouriDiscover last-minute flight deals from South Dakota to Missouri. Data last updated October 27, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to Missouri. Data last updated October 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:32 am -
1 stop6h 49m
Mon 11/26:40 pm -
1 stop4h 49m
Deal found 10/24![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:40 pm -
1 stop4h 44m
Wed 11/114:39 pm -
1 stop7h 05m
Deal found 10/22![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:20 pm -
1 stop7h 21m
Wed 11/113:00 pm -
1 stop6h 37m
Deal found 10/23![United Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:55 am -
1 stop4h 55m
Sat 11/148:45 am -
1 stop7h 40m
Deal found 10/26![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:11 am -
2 stops11h 37m
Sat 11/142:50 pm -
1 stop7h 37m
Deal found 10/26![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:58 pm -
1 stop5h 35m
Mon 11/168:15 pm -
1 stop4h 14m
Deal found 10/24![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:22 am -
1 stop4h 49m
Sun 11/155:45 am -
1 stop6h 50m
Deal found 10/25![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:30 am -
1 stop4h 41m
Mon 11/165:20 pm -
1 stop4h 23m
Deal found 10/27![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:36 pm -
1 stop5h 48m
Tue 11/1710:32 am -
1 stop6h 22m
Deal found 10/26![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:08 pm -
1 stop7h 14m
Sun 11/156:00 am -
1 stop6h 28m
Deal found 10/25![American Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 pm -
1 stop6h 22m
Sun 11/2212:28 pm -
1 stop6h 38m
Deal found 10/24![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:50 pm -
1 stop5h 02m
Fri 11/276:00 am -
1 stop5h 31m
Deal found 10/25![United Airlines logo]()
$339
One-way flights from South Dakota to MissouriSearch for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/149:10 pm -
3 stops38h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$140
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:40 am -
1 stop4h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:18 pm -
1 stop4h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:00 pm -
1 stop6h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/233:55 pm -
1 stop4h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:56 pm -
2 stops53h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/269:47 am -
1 stop6h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:06 pm -
2 stops21h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![United Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:00 pm -
3 stops48h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:31 am -
2 stops8h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:50 pm -
3 stops56h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$474
Find flight deals from South Dakota to Missouri
Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated October 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $314 (United Airlines) |
One-way from | $140 (Kiwi.com) |
Popular in | May |
Cheapest in | December |
Average price | $367 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Mon 12/14
9:10 pm-11:17 am
3 stops38h 07m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Quickest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Fri 11/13
7:18 pm-11:59 pm
1 stop4h 41m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
Sioux FallsKansas City
FSD Sioux Falls Joe Foss Field - MCI Kansas City
FSDMCI
Sioux Falls Joe Foss Field
Thu 11/26
1:00 pm-7:32 pm
1 stop6h 32m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
Rapid CitySt. Louis
RAP Rapid City - STL Lambert-St Louis
RAPSTL
Rapid City
Tue 3/23
3:55 pm-9:52 pm
1 stop4h 57m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Mon 11/23
8:31 am-2:41 pm
1 stop6h 10m
Lambert-St Louis
Mon 11/30
12:28 pm-7:06 pm
1 stop6h 38m
$319
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Tue 11/24
8:31 am-2:41 pm
1 stop6h 10m
Lambert-St Louis
Sun 11/29
6:13 am-10:20 am
1 stop4h 07m
$319
Sioux FallsKansas City
FSD Sioux Falls Joe Foss Field - MCI Kansas City
FSDMCI
Sioux Falls Joe Foss Field
Tue 12/29
5:00 am-10:03 am
1 stop5h 03m
Kansas City
Fri 1/1
6:00 am-11:58 am
1 stop5h 58m
$319
Sioux FallsKansas City
FSD Sioux Falls Joe Foss Field - MCI Kansas City
FSDMCI
Sioux Falls Joe Foss Field
Sun 11/1
1:56 pm-7:47 pm
2 stops53h 51m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
Sioux FallsSpringfield
FSD Sioux Falls Joe Foss Field - SGF Springfield-Branson
FSDSGF
Sioux Falls Joe Foss Field
Wed 11/11
6:00 am-10:55 am
1 stop4h 55m
Springfield-Branson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$333
Rapid CitySt. Louis
RAP Rapid City - STL Lambert-St Louis
RAPSTL
Rapid City
Sat 12/26
9:47 am-5:00 pm
1 stop6h 13m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$334
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from South Dakota to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
FSD-STL
FSD-MCI
RAP-MCI
RAP-STL
FSD-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to Missouri
USSD-USMO
FSD-STL
FSD-MCI
RAP-MCI
RAP-STL
What is the cheapest month to book a flight from South Dakota to Missouri?
Currently, December is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $333). Flying from South Dakota to Missouri in June is currently the most expensive (average of $617). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Dakota to Missouri?
Airfare is below average for this route at the moment.
South Dakota to Missouri flights typically cost between $418 and $487 in January.The cheapest round-trip price found within the last 5 days was $314 on United Airlines (Jan 27-Jan 30).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 27, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Dakota to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Dakota to Missouri by cabin class
Find flights from South Dakota to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Dakota and Missouri flights
Browse other South Dakota and Missouri flight options. Last updated on October 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to South Dakota after your stay in Missouri
South Dakota to Missouri flights
Consider these flights traveling from South Dakota to Missouri.
Top 3 airlines flying from South Dakota to Missouri
Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$192 | Average$434 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$208 | Average$363 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$441 | FlexibilityNo cancel fee | On-time71% |