$189+ Cheap flights from South Dakota to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
RAP — MCI
Jun 20 — Jun 271
Round-trip
1 adult, Economy
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Cheapest flights from South Dakota to MissouriExplore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
This Frontier deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:14 pm
FSD
- MCI
1 stop16h 46m
Frontier
Wed 7/81:45 pm
MCI
- FSD
1 stop5h 38m
Frontier
Deal found 5/21![Frontier logo]()
$249
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Sun 7/55:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/19![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:30 am
FSD
- MCI
1 stop7h 25m
American Airlines
Sat 9/126:38 am
MCI
- FSD
1 stop5h 08m
American Airlines
Deal found 5/20![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:35 am
FSD
- STL
1 stop4h 36m
United Airlines
Fri 7/175:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/19![United Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
RAP
- STL
1 stop5h 11m
United Airlines
Wed 6/245:10 am
STL
- RAP
1 stop5h 10m
United Airlines
Deal found 5/19![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/88:14 pm
STL
- FSD
1 stop4h 06m
American Airlines
Deal found 5/20![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
FSD
- MCI
1 stop4h 50m
United Airlines
Sun 6/76:00 am
MCI
- FSD
1 stop4h 40m
United Airlines
Deal found 5/21![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:35 pm
RAP
- STL
1 stop6h 55m
United Airlines
Wed 6/245:10 am
STL
- RAP
1 stop5h 10m
United Airlines
Deal found 5/19![United Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:00 am
FSD
- STL
1 stop3h 46m
Delta
Wed 6/246:21 am
STL
- FSD
1 stop3h 55m
Delta
Deal found 5/18![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:35 pm
FSD
- MCI
1 stop3h 15m
Delta
Tue 6/95:37 pm
MCI
- FSD
1 stop5h 35m
Delta
Deal found 5/17![Delta logo]()
$329
This Booking.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:14 pm
FSD
- STL
1 stop23h 09m
Frontier
Sun 6/217:38 pm
STL
- FSD
1 stop23h 41m
Frontier
Deal found 5/18![Frontier logo]()
$333
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 pm
RAP
- MCI
1 stop6h 25m
American Airlines
Tue 6/235:31 am
MCI
- RAP
1 stop5h 18m
American Airlines
Deal found 5/19![American Airlines logo]()
$335
Best flights from South Dakota to MissouriDiscover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
Discover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Sun 7/55:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/19![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:00 pm
RAP
- STL
1 stop6h 18m
Delta
Mon 11/169:45 am
STL
- RAP
1 stop5h 07m
Delta
Deal found 5/17![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/88:14 pm
STL
- FSD
1 stop4h 06m
American Airlines
Deal found 5/20![American Airlines logo]()
$319
This Booking.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:14 pm
FSD
- STL
1 stop23h 09m
Frontier
Sun 6/217:38 pm
STL
- FSD
1 stop23h 41m
Frontier
Deal found 5/18![Frontier logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:47 pm
FSD
- SGF
1 stop21h 54m
Allegiant Air
Fri 8/78:42 am
SGF
- FSD
1 stop25h 01m
Allegiant Air
Deal found 5/18![Allegiant Air logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:14 pm
FSD
- STL
1 stop23h 09m
Multiple Airlines
Sun 6/212:00 pm
STL
- FSD
2 stops30h 17m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$516
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:51 pm
FSD
- MCI
1 stop4h 34m
United Airlines
Sat 6/276:41 pm
MCI
- FSD
1 stop4h 50m
United Airlines
Deal found 5/18![United Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
FSD
- MCI
1 stop4h 50m
United Airlines
Sun 6/76:00 am
MCI
- FSD
1 stop4h 40m
United Airlines
Deal found 5/21![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Mon 6/225:10 am
STL
- FSD
1 stop5h 30m
United Airlines
Deal found 5/17![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:07 am
RAP
- STL
1 stop4h 39m
Delta
Sun 6/215:36 pm
STL
- RAP
1 stop6h 01m
Delta
Deal found 5/19![Delta logo]()
$423
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:55 pm
RAP
- STL
1 stop6h 10m
American Airlines
Sun 7/195:32 am
STL
- RAP
1 stop5h 15m
American Airlines
Deal found 5/20![American Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:35 am
FSD
- STL
1 stop4h 36m
United Airlines
Sun 8/25:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/18![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:14 pm
FSD
- STL
1 stop23h 09m
Frontier
Mon 6/227:03 pm
STL
- FSD
2 stops48h 16m
Frontier
Deal found 5/17![Frontier logo]()
$479
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:47 am
FSD
- STL
1 stop4h 15m
United Airlines
Sat 9/55:59 pm
STL
- FSD
1 stop4h 53m
United Airlines
Deal found 5/17![United Airlines logo]()
$341
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:21 pm
RAP
- MCI
1 stop7h 04m
United Airlines
Tue 6/236:00 am
MCI
- RAP
1 stop4h 20m
United Airlines
Deal found 5/19![United Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/71:30 pm
FSD
- MCI
1 stop3h 18m
Delta
Thu 7/96:23 am
MCI
- FSD
1 stop6h 26m
Delta
Deal found 5/21![Delta logo]()
$517
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:43 am
FSD
- MCI
1 stop6h 27m
United Airlines
Sat 10/247:10 pm
MCI
- FSD
1 stop4h 34m
United Airlines
Deal found 5/19![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:28 am
RAP
- SGF
2 stops15h 17m
American Airlines
Tue 8/187:55 pm
SGF
- RAP
1 stop19h 56m
American Airlines
Deal found 5/19![American Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:05 pm
FSD
- MCI
1 stop6h 25m
United Airlines
Sat 9/55:13 pm
MCI
- FSD
1 stop6h 31m
United Airlines
Deal found 5/16![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:25 pm
RAP
- SGF
1 stop17h 52m
American Airlines
Mon 7/137:53 pm
SGF
- RAP
1 stop16h 21m
American Airlines
Deal found 5/16![American Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 pm
FSD
- MCI
1 stop4h 43m
United Airlines
Mon 6/227:11 pm
MCI
- FSD
1 stop4h 42m
United Airlines
Deal found 5/17![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:53 pm
RAP
- STL
1 stop5h 04m
United Airlines
Wed 6/101:38 pm
STL
- RAP
1 stop6h 35m
United Airlines
Deal found 5/21![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:48 am
RAP
- SGF
2 stops10h 25m
Delta
Tue 8/1811:38 am
SGF
- RAP
2 stops11h 59m
Delta
Deal found 5/19![Delta logo]()
$770
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:05 pm
FSD
- MCI
1 stop6h 20m
United Airlines
Tue 6/91:50 pm
MCI
- FSD
1 stop6h 18m
United Airlines
Deal found 5/18![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:58 pm
RAP
- SGF
1 stop6h 00m
American Airlines
Fri 10/96:00 am
SGF
- RAP
1 stop4h 49m
American Airlines
Deal found 5/16![American Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:41 pm
RAP
- MCI
1 stop5h 49m
United Airlines
Sat 8/225:13 pm
MCI
- RAP
1 stop4h 25m
United Airlines
Deal found 5/19![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:47 pm
RAP
- SGF
1 stop4h 55m
United Airlines
Tue 8/185:05 pm
SGF
- RAP
1 stop4h 33m
United Airlines
Deal found 5/19![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:31 pm
RAP
- STL
1 stop7h 29m
United Airlines
Sat 8/224:40 pm
STL
- RAP
1 stop6h 48m
United Airlines
Deal found 5/16![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:00 am
RAP
- SGF
1 stop4h 37m
United Airlines
Sun 8/306:37 pm
SGF
- RAP
2 stops15h 51m
United Airlines
Deal found 5/18![United Airlines logo]()
$520
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:26 pm
FSD
- SGF
2 stops8h 55m
Delta
Fri 8/711:38 am
SGF
- FSD
2 stops8h 07m
Delta
Deal found 5/18![Delta logo]()
$1,563
Last-minute flights from South Dakota to MissouriDiscover last-minute flight deals from South Dakota to Missouri. Data last updated May 21, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to Missouri. Data last updated May 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:00 am
FSD
- STL
1 stop3h 46m
Delta
Wed 6/246:21 am
STL
- FSD
1 stop3h 55m
Delta
Deal found 5/18![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:35 pm
FSD
- MCI
1 stop3h 15m
Delta
Tue 6/95:37 pm
MCI
- FSD
1 stop5h 35m
Delta
Deal found 5/17![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/88:14 pm
STL
- FSD
1 stop4h 06m
American Airlines
Deal found 5/20![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
FSD
- MCI
1 stop4h 50m
United Airlines
Sun 6/76:00 am
MCI
- FSD
1 stop4h 40m
United Airlines
Deal found 5/21![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:35 pm
RAP
- STL
1 stop6h 55m
United Airlines
Wed 6/245:10 am
STL
- RAP
1 stop5h 10m
United Airlines
Deal found 5/19![United Airlines logo]()
$324
This Booking.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:14 pm
FSD
- STL
1 stop23h 09m
Frontier
Sun 6/217:38 pm
STL
- FSD
1 stop23h 41m
Frontier
Deal found 5/18![Frontier logo]()
$333
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Mon 6/225:10 am
STL
- FSD
1 stop5h 30m
United Airlines
Deal found 5/17![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 pm
RAP
- MCI
1 stop6h 25m
American Airlines
Tue 6/235:31 am
MCI
- RAP
1 stop5h 18m
American Airlines
Deal found 5/19![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
RAP
- STL
1 stop5h 11m
United Airlines
Wed 6/245:10 am
STL
- RAP
1 stop5h 10m
United Airlines
Deal found 5/19![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:51 pm
FSD
- MCI
1 stop4h 34m
United Airlines
Sat 6/276:41 pm
MCI
- FSD
1 stop4h 50m
United Airlines
Deal found 5/18![United Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Sun 7/55:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/19![United Airlines logo]()
$289
This Frontier deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:14 pm
FSD
- MCI
1 stop16h 46m
Frontier
Wed 7/81:45 pm
MCI
- FSD
1 stop5h 38m
Frontier
Deal found 5/21![Frontier logo]()
$249
One-way flights from South Dakota to MissouriSearch for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
Search for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/289:54 pm
RAP
- MCI
3 stops57h 53m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$189
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:48 am
RAP
- MCI
1 stop4h 01m
Delta
Deal found 5/19![Delta logo]()
$212
This Mytrip deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:18 pm
FSD
- STL
1 stop24h 05m
Frontier
Deal found 5/21![Frontier logo]()
$215
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:41 pm
RAP
- MCI
1 stop5h 14m
American Airlines
Deal found 5/16![American Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/289:54 pm
RAP
- STL
2 stops19h 24m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$226
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:29 pm
RAP
- STL
1 stop5h 54m
Delta
Deal found 5/20![Delta logo]()
$241
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:40 am
FSD
- STL
1 stop4h 31m
United Airlines
Deal found 5/16![United Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:05 pm
FSD
- MCI
1 stop6h 20m
United Airlines
Deal found 5/21![United Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:34 pm
RAP
- STL
2 stops16h 18m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$260
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:00 pm
RAP
- MCI
1 stop6h 25m
American Airlines
Deal found 5/19![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/284:28 pm
RAP
- STL
1 stop5h 55m
Delta
Deal found 5/17![Delta logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:05 pm
RAP
- STL
3 stops29h 10m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$266
Find flight deals from South Dakota to Missouri
Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated May 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (United Airlines) |
One-way from | $189 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $303 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 6/26
6:51 pm-11:57 pm
1 stop5h 06m
Lambert-St Louis
Sun 7/5
5:33 pm-11:31 pm
1 stop5h 58m
$289
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 6/25
6:51 pm-11:25 pm
1 stop4h 34m
Kansas City
Sat 6/27
6:41 pm-11:31 pm
1 stop4h 50m
$289
Rapid CitySt. Louis
RAP - STL
RAPSTL
Rapid City
Thu 11/12
4:00 pm-11:18 pm
1 stop6h 18m
Lambert-St Louis
Mon 11/16
9:45 am-1:52 pm
1 stop5h 07m
$309
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 6/4
5:35 pm-11:59 pm
1 stop6h 24m
Lambert-St Louis
Mon 6/8
8:14 pm-12:20 am
1 stop4h 06m
$319
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 6/4
6:00 am-10:50 am
1 stop4h 50m
Kansas City
Sun 6/7
6:00 am-10:40 am
1 stop4h 40m
$319
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 6/15
8:14 pm-7:23 pm
1 stop23h 09m
Lambert-St Louis
Sun 6/21
7:38 pm-7:19 pm
1 stop23h 41m
$333
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 6/15
6:51 pm-11:57 pm
1 stop5h 06m
Lambert-St Louis
Mon 6/22
5:10 am-10:40 am
1 stop5h 30m
$338
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 7/30
7:35 am-12:11 pm
1 stop4h 36m
Lambert-St Louis
Sun 8/2
5:33 pm-11:31 pm
1 stop5h 58m
$339
Quickest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Tue 9/1
7:47 am-12:02 pm
1 stop4h 15m
Lambert-St Louis
Sat 9/5
5:59 pm-10:52 pm
1 stop4h 53m
$341
Rapid CityKansas City
RAP - MCI
RAPMCI
Rapid City
Tue 6/16
3:21 pm-11:25 pm
1 stop7h 04m
Kansas City
Tue 6/23
6:00 am-9:20 am
1 stop4h 20m
$350
Showing 1-10 of 58 resultsSorted by cheapest first
Best time to book a flight from South Dakota to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
FSD-STL
RAP-STL
FSD-SGF
FSD-MCI
RAP-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to Missouri
USSD-USMO
FSD-STL
RAP-STL
FSD-SGF
FSD-MCI
What is the cheapest month to book a flight from South Dakota to Missouri?
Currently, January is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $208). Flying from South Dakota to Missouri in February is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Dakota to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 21, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Dakota to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Dakota to Missouri by cabin class
Find flights from South Dakota to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Dakota and Missouri flights
Browse other South Dakota and Missouri flight options. Last updated on May 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to South Dakota after your stay in Missouri
South Dakota to Missouri flights
Consider these flights traveling from South Dakota to Missouri.
Top 3 airlines flying from South Dakota to Missouri
Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$326 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$212 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$243 | Average$418 | FlexibilityNo cancel fee | On-time71% |