$204+ Cheap flights from South Dakota to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Aug 21 — Aug 281
Round-trip
1 adult, Economy
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Cheapest flights from South Dakota to MissouriExplore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop4h 18m
United Airlines
Tue 9/224:40 pm
STL
- FSD
1 stop7h 04m
United Airlines
Deal found 7/21![United Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop5h 46m
American Airlines
Tue 9/2211:01 am
STL
- FSD
2 stops8h 41m
American Airlines
Deal found 7/19![American Airlines logo]()
$276
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- STL
1 stop6h 54m
United Airlines
Sat 8/225:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:57 pm
FSD
- STL
2 stops11h 01m
American Airlines
Sat 8/225:13 pm
STL
- FSD
1 stop7h 17m
American Airlines
Deal found 7/18![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm
FSD
- STL
1 stop5h 44m
American Airlines
Sun 9/275:43 am
STL
- FSD
1 stop6h 33m
American Airlines
Deal found 7/19![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:05 am
FSD
- MCI
1 stop3h 27m
Delta
Sun 9/136:20 am
MCI
- FSD
1 stop3h 59m
Delta
Deal found 7/20![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop5h 46m
American Airlines
Mon 9/2111:01 am
STL
- FSD
1 stop13h 28m
American Airlines
Deal found 7/22![American Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:05 pm
FSD
- STL
1 stop3h 42m
Delta
Mon 9/215:47 pm
STL
- FSD
1 stop5h 04m
Delta
Deal found 7/20![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:31 pm
RAP
- MCI
1 stop5h 11m
United Airlines
Sun 8/236:00 am
MCI
- RAP
1 stop4h 28m
United Airlines
Deal found 7/20![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:56 pm
RAP
- STL
1 stop5h 47m
American Airlines
Sun 9/277:27 am
STL
- RAP
1 stop4h 48m
American Airlines
Deal found 7/19![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:39 pm
RAP
- MCI
2 stops10h 56m
American Airlines
Sun 8/235:14 pm
MCI
- RAP
1 stop5h 50m
American Airlines
Deal found 7/20![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:41 pm
RAP
- SGF
1 stop6h 01m
United Airlines
Wed 8/261:37 pm
SGF
- RAP
1 stop5h 21m
United Airlines
Deal found 7/22![United Airlines logo]()
$319
Best flights from South Dakota to MissouriDiscover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
Discover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop4h 18m
United Airlines
Tue 9/224:40 pm
STL
- FSD
1 stop7h 04m
United Airlines
Deal found 7/21![United Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:23 pm
FSD
- STL
1 stop6h 51m
American Airlines
Sat 8/228:06 pm
STL
- FSD
1 stop4h 24m
American Airlines
Deal found 7/20![American Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:05 am
FSD
- MCI
1 stop3h 27m
Delta
Sun 9/136:20 am
MCI
- FSD
1 stop3h 59m
Delta
Deal found 7/20![Delta logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:31 pm
FSD
- MCI
1 stop17h 51m
Multiple Airlines
Sat 10/172:17 pm
MCI
- FSD
2 stops21h 19m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- STL
1 stop6h 54m
United Airlines
Sat 8/225:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:09 pm
FSD
- STL
2 stops10h 49m
American Airlines
Sun 12/67:29 am
STL
- FSD
1 stop6h 49m
American Airlines
Deal found 7/19![American Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:05 pm
FSD
- STL
1 stop3h 42m
Delta
Mon 9/215:47 pm
STL
- FSD
1 stop5h 04m
Delta
Deal found 7/19![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:33 pm
FSD
- STL
1 stop7h 05m
United Airlines
Mon 9/216:53 pm
STL
- FSD
1 stop4h 19m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm
FSD
- STL
1 stop5h 44m
American Airlines
Sun 9/275:43 am
STL
- FSD
1 stop6h 33m
American Airlines
Deal found 7/19![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:31 pm
RAP
- STL
1 stop5h 45m
Delta
Wed 9/306:15 am
STL
- RAP
1 stop4h 46m
Delta
Deal found 7/20![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:56 pm
FSD
- MCI
1 stop7h 24m
American Airlines
Sat 9/1212:19 pm
MCI
- FSD
1 stop5h 52m
American Airlines
Deal found 7/21![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:31 pm
RAP
- MCI
1 stop5h 11m
United Airlines
Sun 8/236:00 am
MCI
- RAP
1 stop4h 28m
United Airlines
Deal found 7/20![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:00 pm
RAP
- STL
1 stop6h 18m
Delta
Mon 11/169:45 am
STL
- RAP
1 stop7h 01m
Delta
Deal found 7/21![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:58 pm
RAP
- SGF
1 stop4h 44m
United Airlines
Sat 8/225:30 am
SGF
- RAP
1 stop7h 25m
United Airlines
Deal found 7/18![United Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:57 pm
FSD
- STL
1 stop5h 08m
American Airlines
Mon 8/103:32 pm
STL
- FSD
1 stop4h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:40 am
FSD
- STL
1 stop4h 32m
Delta
Tue 9/2211:21 am
STL
- FSD
1 stop4h 25m
Delta
Deal found 7/22![Delta logo]()
$365
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:10 am
FSD
- STL
1 stop5h 33m
United Airlines
Sat 10/315:00 am
STL
- FSD
1 stop5h 32m
United Airlines
Deal found 7/21![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:21 pm
RAP
- SGF
1 stop6h 22m
American Airlines
Sun 8/303:53 pm
SGF
- RAP
1 stop7h 11m
American Airlines
Deal found 7/20![American Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
FSD
- MCI
1 stop6h 37m
United Airlines
Mon 8/241:43 pm
MCI
- FSD
1 stop6h 24m
United Airlines
Deal found 7/19![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am
FSD
- MCI
1 stop4h 51m
United Airlines
Mon 8/246:00 am
MCI
- FSD
1 stop4h 43m
United Airlines
Deal found 7/21![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:50 pm
FSD
- MCI
1 stop4h 40m
United Airlines
Mon 8/175:08 pm
MCI
- FSD
1 stop6h 14m
United Airlines
Deal found 7/19![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:22 am
RAP
- STL
1 stop4h 12m
United Airlines
Mon 8/2412:59 pm
STL
- RAP
2 stops8h 38m
United Airlines
Deal found 7/20![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:31 pm
FSD
- SGF
1 stop14h 37m
American Airlines
Sun 11/1510:38 am
SGF
- FSD
1 stop8h 23m
American Airlines
Deal found 7/19![American Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am
RAP
- STL
1 stop4h 37m
United Airlines
Mon 11/163:15 pm
STL
- RAP
2 stops7h 53m
United Airlines
Deal found 7/21![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
RAP
- MCI
1 stop4h 37m
United Airlines
Tue 9/19:14 am
MCI
- RAP
1 stop4h 10m
United Airlines
Deal found 7/18![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:46 am
RAP
- SGF
2 stops10h 35m
Delta
Sun 8/306:06 am
SGF
- RAP
2 stops10h 43m
Delta
Deal found 7/19![Delta logo]()
$693
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/264:41 pm
RAP
- SGF
1 stop6h 01m
United Airlines
Sat 8/291:37 pm
SGF
- RAP
1 stop5h 06m
United Airlines
Deal found 7/18![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
RAP
- STL
1 stop4h 40m
United Airlines
Tue 9/14:40 pm
STL
- RAP
1 stop6h 53m
United Airlines
Deal found 7/19![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:41 pm
FSD
- SGF
1 stop4h 40m
United Airlines
Sun 9/205:30 am
SGF
- FSD
1 stop5h 14m
United Airlines
Deal found 7/20![United Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:05 pm
FSD
- SGF
2 stops9h 03m
Delta
Sun 9/2011:37 am
SGF
- FSD
2 stops8h 06m
Delta
Deal found 7/19![Delta logo]()
$1,431
Last-minute flights from South Dakota to MissouriDiscover last-minute flight deals from South Dakota to Missouri. Data last updated July 22, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to Missouri. Data last updated July 22, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:30 pm
RAP
- STL
1 stop5h 56m
Delta
Sat 8/85:34 pm
STL
- RAP
1 stop6h 03m
Delta
Deal found 7/19![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:57 pm
FSD
- STL
1 stop5h 08m
American Airlines
Mon 8/103:32 pm
STL
- FSD
1 stop4h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:50 pm
FSD
- MCI
1 stop4h 40m
United Airlines
Mon 8/175:08 pm
MCI
- FSD
1 stop6h 14m
United Airlines
Deal found 7/20![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- STL
1 stop6h 54m
United Airlines
Sat 8/225:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:57 pm
FSD
- STL
2 stops11h 01m
American Airlines
Sat 8/225:13 pm
STL
- FSD
1 stop7h 17m
American Airlines
Deal found 7/18![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:58 pm
RAP
- SGF
1 stop4h 44m
United Airlines
Sat 8/225:30 am
SGF
- RAP
1 stop7h 25m
United Airlines
Deal found 7/18![United Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:31 pm
RAP
- STL
1 stop7h 29m
United Airlines
Mon 8/244:40 pm
STL
- RAP
1 stop4h 57m
United Airlines
Deal found 7/20![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:41 pm
RAP
- SGF
1 stop6h 01m
United Airlines
Wed 8/261:37 pm
SGF
- RAP
1 stop5h 21m
United Airlines
Deal found 7/22![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:57 pm
FSD
- STL
1 stop6h 54m
American Airlines
Sun 8/238:07 pm
STL
- FSD
1 stop4h 18m
American Airlines
Deal found 7/18![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:57 pm
FSD
- STL
2 stops11h 17m
American Airlines
Sat 8/225:00 am
STL
- FSD
1 stop6h 36m
American Airlines
Deal found 7/20![American Airlines logo]()
$320
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:31 pm
RAP
- MCI
1 stop5h 11m
United Airlines
Sun 8/236:00 am
MCI
- RAP
1 stop4h 28m
United Airlines
Deal found 7/20![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:39 pm
RAP
- MCI
2 stops10h 56m
American Airlines
Sun 8/235:14 pm
MCI
- RAP
1 stop5h 50m
American Airlines
Deal found 7/20![American Airlines logo]()
$314
One-way flights from South Dakota to MissouriSearch for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
Search for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:34 pm
RAP
- STL
3 stops41h 06m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:34 pm
RAP
- MCI
2 stops20h 48m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$213
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:56 pm
FSD
- STL
1 stop5h 08m
American Airlines
Deal found 7/18![American Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:58 pm
FSD
- STL
3 stops44h 42m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:39 pm
RAP
- SGF
1 stop5h 39m
American Airlines
Deal found 7/22![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:00 am
RAP
- STL
1 stop6h 40m
United Airlines
Deal found 7/18![United Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:58 pm
RAP
- SGF
1 stop4h 44m
United Airlines
Deal found 7/22![United Airlines logo]()
$274
This deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:12 am
FSD
- STL
1 stop4h 26m
United Airlines
Deal found 7/19![United Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:08 pm
FSD
- MCI
2 stops19h 39m
Frontier
Deal found 7/20![Frontier logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/71:31 pm
RAP
- STL
1 stop7h 29m
United Airlines
Deal found 7/21![United Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:50 pm
RAP
- MCI
2 stops14h 10m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:36 pm
FSD
- MCI
1 stop24h 11m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$322
Find flight deals from South Dakota to Missouri
Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated July 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (United Airlines) |
One-way from | $204 (Kiwi.com) |
Popular in | September |
Cheapest in | July |
Average price | $288 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 9/19
6:41 pm-10:59 pm
1 stop4h 18m
Lambert-St Louis
Tue 9/22
4:40 pm-11:44 pm
1 stop7h 04m
$271
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 8/20
5:23 pm-12:14 am
1 stop6h 51m
Lambert-St Louis
Sat 8/22
8:06 pm-12:30 am
1 stop4h 24m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 8/15
3:06 pm-10:00 pm
1 stop6h 54m
Lambert-St Louis
Sat 8/22
5:30 pm-11:22 pm
1 stop5h 52m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 9/19
1:33 pm-8:38 pm
1 stop7h 05m
Lambert-St Louis
Mon 9/21
6:53 pm-11:12 pm
1 stop4h 19m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 12/2
1:09 pm-11:58 pm
2 stops10h 49m
Lambert-St Louis
Sun 12/6
7:29 am-2:18 pm
1 stop6h 49m
$285
Quickest round-trip
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 9/10
5:05 am-8:32 am
1 stop3h 27m
Kansas City
Sun 9/13
6:20 am-10:19 am
1 stop3h 59m
$289
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 9/25
5:59 pm-11:43 pm
1 stop5h 44m
Lambert-St Louis
Sun 9/27
5:43 am-12:16 pm
1 stop6h 33m
$289
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 9/10
12:56 pm-8:20 pm
1 stop7h 24m
Kansas City
Sat 9/12
12:19 pm-6:11 pm
1 stop5h 52m
$289
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 9/19
1:05 pm-4:47 pm
1 stop3h 42m
Lambert-St Louis
Mon 9/21
5:47 pm-10:51 pm
1 stop5h 04m
$305
Rapid CitySt. Louis
RAP - STL
RAPSTL
Rapid City
Wed 9/9
4:31 pm-11:16 pm
1 stop5h 45m
Lambert-St Louis
Wed 9/30
6:15 am-10:01 am
1 stop4h 46m
$309
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Dakota to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
FSD-STL
FSD-MCI
RAP-STL
RAP-MCI
RAP-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to Missouri
USSD-USMO
FSD-STL
FSD-MCI
RAP-STL
RAP-MCI
What is the cheapest month to book a flight from South Dakota to Missouri?
Currently, December is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $333). Flying from South Dakota to Missouri in June is currently the most expensive (average of $617). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 22, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Dakota to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Dakota to Missouri by cabin class
Find flights from South Dakota to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Dakota and Missouri flights
Browse other South Dakota and Missouri flight options. Last updated on July 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to South Dakota after your stay in Missouri
South Dakota to Missouri flights
Consider these flights traveling from South Dakota to Missouri.
Top 3 airlines flying from South Dakota to Missouri
Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$351 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$335 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$424 | FlexibilityNo cancel fee | On-time69% |