$259+ Cheap flights from Sioux Falls to St. Louis (FSD - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Jul 26 — Aug 21
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to St. LouisExplore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am
FSD
- STL
1 stop7h 15m
American Airlines
Sat 8/2910:16 am
STL
- FSD
1 stop7h 20m
American Airlines
Deal found 6/21![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:34 pm
FSD
- STL
1 stop6h 24m
American Airlines
Tue 7/216:55 am
STL
- FSD
1 stop4h 35m
American Airlines
Deal found 6/23![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:02 am
FSD
- STL
1 stop7h 00m
American Airlines
Fri 7/109:44 am
STL
- FSD
1 stop7h 10m
American Airlines
Deal found 6/23![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:00 am
FSD
- STL
1 stop3h 46m
Delta
Tue 7/215:36 pm
STL
- FSD
1 stop5h 30m
Delta
Deal found 6/26![Delta logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:35 am
FSD
- STL
1 stop4h 36m
United Airlines
Sun 8/95:59 pm
STL
- FSD
1 stop5h 32m
United Airlines
Deal found 6/25![United Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:56 pm
FSD
- STL
1 stop7h 47m
United Airlines
Sat 7/115:59 pm
STL
- FSD
1 stop5h 32m
United Airlines
Deal found 6/22![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:05 pm
FSD
- STL
1 stop6h 52m
United Airlines
Fri 7/317:05 pm
STL
- FSD
1 stop4h 26m
United Airlines
Deal found 6/23![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:20 pm
FSD
- STL
1 stop4h 38m
American Airlines
Sun 12/68:41 am
STL
- FSD
1 stop4h 53m
American Airlines
Deal found 6/23![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:35 am
FSD
- STL
1 stop6h 59m
United Airlines
Wed 9/25:10 am
STL
- FSD
1 stop5h 33m
United Airlines
Deal found 6/22![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:11 am
FSD
- STL
1 stop6h 41m
American Airlines
Sun 7/55:32 am
STL
- FSD
1 stop6h 38m
American Airlines
Deal found 6/25![American Airlines logo]()
$359
Best flights from Sioux Falls to St. LouisDiscover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 26, 2026.
Discover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 26, 2026.
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am
FSD
- STL
1 stop7h 15m
American Airlines
Sat 8/2910:16 am
STL
- FSD
1 stop7h 20m
American Airlines
Deal found 6/21![American Airlines logo]()
$280
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:39 pm
FSD
- STL
1 stop4h 20m
United Airlines
Sat 8/299:00 am
STL
- FSD
1 stop7h 23m
United Airlines
Deal found 6/25![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/241:30 pm
FSD
- STL
2 stops10h 23m
Delta
Fri 7/315:36 pm
STL
- FSD
1 stop5h 30m
Delta
Deal found 6/23![Delta logo]()
$439
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:23 pm
FSD
- STL
1 stop6h 51m
American Airlines
Mon 8/175:42 am
STL
- FSD
1 stop6h 35m
American Airlines
Deal found 6/25![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:35 am
FSD
- STL
1 stop6h 59m
United Airlines
Wed 9/25:10 am
STL
- FSD
1 stop5h 33m
United Airlines
Deal found 6/24![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:00 am
FSD
- STL
2 stops8h 05m
Delta
Tue 7/215:36 pm
STL
- FSD
1 stop5h 30m
Delta
Deal found 6/23![Delta logo]()
$469
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am
FSD
- STL
1 stop7h 15m
American Airlines
Fri 8/288:07 pm
STL
- FSD
1 stop15h 29m
American Airlines
Deal found 6/21![American Airlines logo]()
$432
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:00 am
FSD
- STL
1 stop5h 23m
Delta
Fri 8/285:34 pm
STL
- FSD
1 stop5h 17m
Delta
Deal found 6/21![Delta logo]()
$517
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:34 pm
FSD
- STL
1 stop6h 24m
American Airlines
Thu 7/165:58 pm
STL
- FSD
1 stop6h 20m
American Airlines
Deal found 6/22![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:16 pm
FSD
- STL
1 stop6h 14m
American Airlines
Mon 11/307:58 pm
STL
- FSD
1 stop17h 15m
American Airlines
Deal found 6/21![American Airlines logo]()
$583
Last-minute flights from Sioux Falls to St. LouisDiscover last-minute flight deals from Sioux Falls to St. Louis. Data last updated June 26, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to St. Louis. Data last updated June 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:02 am
FSD
- STL
1 stop7h 00m
American Airlines
Fri 7/109:44 am
STL
- FSD
1 stop7h 10m
American Airlines
Deal found 6/23![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:11 am
FSD
- STL
1 stop6h 41m
American Airlines
Sun 7/55:32 am
STL
- FSD
1 stop6h 38m
American Airlines
Deal found 6/25![American Airlines logo]()
$359
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:40 pm
FSD
- STL
1 stop26h 43m
Frontier
Thu 7/98:08 pm
STL
- FSD
1 stop23h 15m
Frontier
Deal found 6/22![Frontier logo]()
$447
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:56 pm
FSD
- STL
1 stop7h 47m
United Airlines
Sat 7/115:59 pm
STL
- FSD
1 stop5h 32m
United Airlines
Deal found 6/22![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:34 pm
FSD
- STL
1 stop6h 24m
American Airlines
Thu 7/165:58 pm
STL
- FSD
1 stop6h 20m
American Airlines
Deal found 6/22![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:34 pm
FSD
- STL
1 stop6h 24m
American Airlines
Tue 7/216:55 am
STL
- FSD
1 stop4h 35m
American Airlines
Deal found 6/23![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:00 am
FSD
- STL
1 stop3h 46m
Delta
Tue 7/215:36 pm
STL
- FSD
1 stop5h 30m
Delta
Deal found 6/26![Delta logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:05 pm
FSD
- STL
1 stop6h 52m
United Airlines
Fri 7/317:05 pm
STL
- FSD
1 stop4h 26m
United Airlines
Deal found 6/23![United Airlines logo]()
$334
One-way flights from Sioux Falls to St. LouisSearch for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 26, 2026.
Search for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 26, 2026.
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:40 pm
FSD
- STL
1 stop7h 13m
American Airlines
Deal found 6/22![American Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:05 pm
FSD
- STL
1 stop6h 52m
United Airlines
Deal found 6/26![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:30 pm
FSD
- STL
2 stops10h 23m
Delta
Deal found 6/26![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:34 pm
FSD
- STL
1 stop6h 18m
American Airlines
Deal found 6/22![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:36 pm
FSD
- STL
3 stops23h 42m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$538
Find flight deals from Sioux Falls to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $280 (American Airlines) |
One-way from | $259 (American Airlines) |
Popular in | May |
Cheapest in | September |
Average price | $617 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 8/27
7:30 am-2:45 pm
1 stop7h 15m
Lambert-St Louis
Sat 8/29
10:16 am-5:36 pm
1 stop7h 20m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 8/13
5:23 pm-12:14 am
1 stop6h 51m
Lambert-St Louis
Mon 8/17
5:42 am-12:17 pm
1 stop6h 35m
$289
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 8/26
6:39 pm-10:59 pm
1 stop4h 20m
Lambert-St Louis
Sat 8/29
9:00 am-4:23 pm
1 stop7h 23m
$341
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 8/29
9:35 am-4:34 pm
1 stop6h 59m
Lambert-St Louis
Wed 9/2
5:10 am-10:43 am
1 stop5h 33m
$341
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 8/27
7:30 am-2:45 pm
1 stop7h 15m
Lambert-St Louis
Fri 8/28
8:07 pm-11:36 am
1 stop15h 29m
$432
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 7/24
1:30 pm-11:53 pm
2 stops10h 23m
Lambert-St Louis
Fri 7/31
5:36 pm-11:06 pm
1 stop5h 30m
$439
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Tue 7/14
5:00 am-1:05 pm
2 stops8h 05m
Lambert-St Louis
Tue 7/21
5:36 pm-11:06 pm
1 stop5h 30m
$469
Quickest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 8/28
5:00 am-10:23 am
1 stop5h 23m
Lambert-St Louis
Fri 8/28
5:34 pm-10:51 pm
1 stop5h 17m
$517
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 7/13
5:34 pm-11:58 pm
1 stop6h 24m
Lambert-St Louis
Thu 7/16
5:58 pm-12:18 am
1 stop6h 20m
$517
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 11/20
1:16 pm-7:30 pm
1 stop6h 14m
Lambert-St Louis
Mon 11/30
7:58 pm-1:13 pm
1 stop17h 15m
$583
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to St. Louis in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.
FSD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to St. Louis
Prices
More
What’s the top layover airport for flights from Sioux Falls to St. Louis?
Share of 1-stop round-trip flights from Sioux Falls to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Sioux Falls to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Sioux Falls to St. Louis?
Average round-trip fare for 1-stop flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $278.
What’s the fastest layover option from Sioux Falls to St. Louis?
Shortest average travel time for 1-stop one-way flights from Sioux Falls to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 4h 24m.
Which airport typically offers the quickest layover for flights from Sioux Falls to St. Louis?
Average layover duration for 1-stop one-way flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Denver (DEN) offer the fastest connection on this route, with an average layover time of 1h 01m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 26, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
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Alternative routes for Sioux Falls to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Sioux Falls and St. Louis flights
Browse other Sioux Falls and St. Louis flight options. Last updated on June 26, 2026.
Other flights from Sioux Falls
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Other flights to St. Louis
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Top 3 airlines flying from Sioux Falls to St. Louis
Discover the top 3 airlines that operate flights from Sioux Falls to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$243 | Average$392 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$249 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$337 | FlexibilityNo cancel fee | On-time69% |