$199+ Cheap flights from Sioux Falls to St. Louis (FSD - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to St. Louis
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Cheapest flights from Sioux Falls to St. LouisExplore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:59 pm -
1 stop5h 44m
Sun 9/207:00 am -
1 stop5h 16m
Deal found 8/5![American Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm -
1 stop5h 46m
Mon 9/217:00 am -
1 stop5h 16m
Deal found 8/7![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
2 stops10h 48m
Sun 9/135:18 pm -
1 stop7h 11m
Deal found 8/7![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:06 pm -
1 stop5h 36m
Sun 9/63:35 pm -
1 stop6h 32m
Deal found 8/6![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:12 am -
1 stop4h 26m
Sat 8/299:00 am -
1 stop7h 23m
Deal found 8/9![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:09 pm -
2 stops10h 49m
Sun 12/67:29 am -
2 stops9h 14m
Deal found 8/6![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:06 pm -
1 stop5h 36m
Sat 8/299:32 am -
2 stops10h 59m
Deal found 8/9![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:39 pm -
1 stop4h 20m
Fri 9/116:53 pm -
1 stop4h 19m
Deal found 8/6![United Airlines logo]()
$344
Best flights from Sioux Falls to St. LouisDiscover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:59 pm -
1 stop5h 44m
Sun 9/207:00 am -
1 stop5h 16m
Deal found 8/5![American Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:12 am -
1 stop4h 26m
Sat 8/299:00 am -
1 stop7h 23m
Deal found 8/9![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2310:58 am -
1 stop3h 33m
Sun 1/106:30 am -
1 stop3h 35m
Deal found 8/9![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop6h 15m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/10![American Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:39 pm -
1 stop4h 20m
Sun 9/65:30 pm -
1 stop5h 52m
Deal found 8/6![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:09 pm -
2 stops10h 49m
Sun 12/67:29 am -
2 stops9h 14m
Deal found 8/6![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:39 pm -
1 stop4h 20m
Fri 9/116:53 pm -
1 stop4h 19m
Deal found 8/6![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:06 pm -
1 stop5h 36m
Sun 8/238:07 pm -
1 stop4h 18m
Deal found 8/7![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:40 am -
1 stop6h 50m
Wed 12/161:30 pm -
1 stop7h 16m
Deal found 8/8![United Airlines logo]()
$351
Last-minute flights from Sioux Falls to St. LouisDiscover last-minute flight deals from Sioux Falls to St. Louis. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to St. Louis. Data last updated August 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:06 pm -
1 stop5h 36m
Sun 8/238:07 pm -
1 stop4h 18m
Deal found 8/7![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:12 am -
1 stop4h 26m
Sat 8/299:00 am -
1 stop7h 23m
Deal found 8/9![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:06 pm -
1 stop5h 36m
Sat 8/299:32 am -
2 stops10h 59m
Deal found 8/9![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:06 pm -
1 stop5h 36m
Sun 9/63:35 pm -
1 stop6h 32m
Deal found 8/6![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:39 pm -
1 stop4h 20m
Fri 9/116:53 pm -
1 stop4h 19m
Deal found 8/6![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
2 stops10h 48m
Sun 9/135:18 pm -
1 stop7h 11m
Deal found 8/7![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:59 pm -
1 stop5h 44m
Sun 9/207:00 am -
1 stop5h 16m
Deal found 8/5![American Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop6h 15m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/10![American Airlines logo]()
$290
One-way flights from Sioux Falls to St. LouisSearch for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2310:00 pm -
1 stop19h 50m
Deal found 8/8![Multiple Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:35 am -
1 stop6h 59m
Deal found 8/9![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:57 pm -
2 stops11h 01m
Deal found 8/9![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:39 pm -
1 stop4h 20m
Deal found 8/9![United Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:30 am -
2 stops9h 13m
Deal found 8/9![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:12 am -
1 stop4h 26m
Deal found 8/7![United Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:50 pm -
3 stops49h 38m
Deal found 8/7![Multiple Airlines logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:38 am -
3 stops41h 21m
Deal found 8/9![Multiple Airlines logo]()
$7,135
Find flight deals from Sioux Falls to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (American Airlines) |
One-way from | $199 (Kiwi.com) |
Popular in | May |
Cheapest in | December |
Average price | $575 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Fri 9/11
5:59 pm-11:43 pm
1 stop5h 44m
Lambert-St Louis
Sun 9/20
7:00 am-12:16 pm
1 stop5h 16m
$281
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Sat 9/19
6:00 am-12:15 pm
1 stop6h 15m
Lambert-St Louis
Mon 9/21
5:18 pm-12:29 am
1 stop7h 11m
$290
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Tue 8/25
11:12 am-3:38 pm
1 stop4h 26m
Lambert-St Louis
Sat 8/29
9:00 am-4:23 pm
1 stop7h 23m
$329
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 12/2
1:09 pm-11:58 pm
2 stops10h 49m
Lambert-St Louis
Sun 12/6
7:29 am-4:43 pm
2 stops9h 14m
$330
Quickest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 12/23
10:58 am-2:31 pm
1 stop3h 33m
Lambert-St Louis
Sun 1/10
6:30 am-10:05 am
1 stop3h 35m
$334
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Fri 9/4
6:39 pm-10:59 pm
1 stop4h 20m
Lambert-St Louis
Sun 9/6
5:30 pm-11:22 pm
1 stop5h 52m
$344
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Fri 9/4
6:39 pm-10:59 pm
1 stop4h 20m
Lambert-St Louis
Fri 9/11
6:53 pm-11:12 pm
1 stop4h 19m
$344
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Thu 8/20
6:06 pm-11:42 pm
1 stop5h 36m
Lambert-St Louis
Sun 8/23
8:07 pm-12:25 am
1 stop4h 18m
$349
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Sat 12/12
7:40 am-2:30 pm
1 stop6h 50m
Lambert-St Louis
Wed 12/16
1:30 pm-8:46 pm
1 stop7h 16m
$351
Cheapest one-way
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Sun 8/23
10:00 pm-5:50 pm
1 stop19h 50m
$199
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to St. Louis in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.
FSD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to St. Louis
Prices
More
What’s the top layover airport for flights from Sioux Falls to St. Louis?
Share of 1-stop round-trip flights from Sioux Falls to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Sioux Falls to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Sioux Falls to St. Louis?
Average round-trip fare for 1-stop flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $278.
What’s the fastest layover option from Sioux Falls to St. Louis?
Shortest average travel time for 1-stop one-way flights from Sioux Falls to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 4h 24m.
Which airport typically offers the quickest layover for flights from Sioux Falls to St. Louis?
Average layover duration for 1-stop one-way flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Denver (DEN) offer the fastest connection on this route, with an average layover time of 1h 01m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 10, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Sioux Falls and St. Louis flights
Browse other Sioux Falls and St. Louis flight options. Last updated on August 10, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Top 3 airlines flying from Sioux Falls to St. Louis
Discover the top 3 airlines that operate flights from Sioux Falls to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$243 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$249 | Average$379 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$367 | FlexibilityNo cancel fee | On-time69% |