$115+ Cheap flights from Sioux Falls to St. Louis (FSD - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to St. LouisExplore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 pm
FSD
- STL
1 stop5h 42m
American Airlines
Mon 8/246:42 am
STL
- FSD
1 stop5h 04m
American Airlines
Deal found 5/7![American Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:54 am
FSD
- STL
1 stop5h 58m
Delta
Tue 8/255:42 pm
STL
- FSD
1 stop5h 09m
Delta
Deal found 5/7![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Sun 7/55:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/10![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 am
FSD
- STL
1 stop4h 05m
Delta
Tue 8/256:20 am
STL
- FSD
1 stop4h 00m
Delta
Deal found 5/7![Delta logo]()
$302
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 am
FSD
- STL
1 stop4h 05m
Delta
Sun 8/236:20 am
STL
- FSD
1 stop4h 00m
Delta
Deal found 5/7![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Sun 6/75:29 am
STL
- FSD
1 stop6h 43m
American Airlines
Deal found 5/10![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:40 am
FSD
- STL
1 stop4h 31m
United Airlines
Mon 7/137:05 pm
STL
- FSD
1 stop4h 26m
United Airlines
Deal found 5/7![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:25 am
FSD
- STL
1 stop5h 09m
United Airlines
Sat 8/155:59 pm
STL
- FSD
1 stop4h 53m
United Airlines
Deal found 5/9![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 am
FSD
- STL
1 stop4h 05m
Delta
Mon 8/245:42 pm
STL
- FSD
1 stop5h 09m
Delta
Deal found 5/7![Delta logo]()
$344
This deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:47 am
FSD
- STL
1 stop4h 15m
United Airlines
Tue 8/255:30 pm
STL
- FSD
1 stop5h 22m
United Airlines
Deal found 5/9![United Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:00 am
FSD
- STL
1 stop7h 57m
United Airlines
Sun 5/177:09 pm
STL
- FSD
1 stop4h 20m
United Airlines
Deal found 5/7![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Sun 5/175:51 am
STL
- FSD
1 stop6h 08m
American Airlines
Deal found 5/10![American Airlines logo]()
$369
Best flights from Sioux Falls to St. LouisDiscover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Sun 7/55:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/10![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 am
FSD
- STL
1 stop4h 05m
Delta
Tue 8/256:20 am
STL
- FSD
1 stop4h 00m
Delta
Deal found 5/7![Delta logo]()
$302
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/19:41 am
STL
- FSD
1 stop7h 14m
American Airlines
Deal found 5/9![American Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:40 am
FSD
- STL
1 stop4h 31m
United Airlines
Mon 7/137:05 pm
STL
- FSD
1 stop4h 26m
United Airlines
Deal found 5/7![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:25 am
FSD
- STL
1 stop5h 09m
United Airlines
Sat 8/155:59 pm
STL
- FSD
1 stop4h 53m
United Airlines
Deal found 5/9![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/229:09 am
STL
- FSD
1 stop7h 01m
American Airlines
Deal found 5/7![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Sun 7/56:55 am
STL
- FSD
1 stop4h 40m
American Airlines
Deal found 5/10![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Fri 6/129:09 am
STL
- FSD
1 stop7h 01m
American Airlines
Deal found 5/9![American Airlines logo]()
$399
Last-minute flights from Sioux Falls to St. LouisDiscover last-minute flight deals from Sioux Falls to St. Louis. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to St. Louis. Data last updated May 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Sun 5/175:51 am
STL
- FSD
1 stop6h 08m
American Airlines
Deal found 5/10![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:00 am
FSD
- STL
1 stop7h 57m
United Airlines
Sun 5/177:09 pm
STL
- FSD
1 stop4h 20m
United Airlines
Deal found 5/7![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/19:41 am
STL
- FSD
1 stop7h 14m
American Airlines
Deal found 5/9![American Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Mon 6/111:25 am
STL
- FSD
2 stops12h 28m
United Airlines
Deal found 5/9![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Sun 6/75:29 am
STL
- FSD
1 stop6h 43m
American Airlines
Deal found 5/10![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:18 pm
FSD
- STL
2 stops10h 11m
United Airlines
Sat 6/61:13 pm
STL
- FSD
1 stop4h 42m
United Airlines
Deal found 5/10![United Airlines logo]()
$643
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Fri 6/125:03 pm
STL
- FSD
1 stop18h 45m
American Airlines
Deal found 5/7![American Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Mon 6/229:09 am
STL
- FSD
1 stop7h 01m
American Airlines
Deal found 5/7![American Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:51 pm
FSD
- STL
1 stop5h 06m
United Airlines
Sun 7/55:33 pm
STL
- FSD
1 stop5h 58m
United Airlines
Deal found 5/10![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:35 pm
FSD
- STL
1 stop6h 24m
American Airlines
Sun 7/56:55 am
STL
- FSD
1 stop4h 40m
American Airlines
Deal found 5/11![American Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:14 pm
FSD
- STL
1 stop22h 39m
Multiple Airlines
Sun 7/54:09 pm
STL
- FSD
2 stops27h 41m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$586
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:14 pm
FSD
- STL
2 stops12h 38m
Frontier
Sun 7/58:08 pm
STL
- FSD
1 stop23h 15m
Frontier
Deal found 5/10![Frontier logo]()
$588
One-way flights from Sioux Falls to St. LouisSearch for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Mytrip deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:18 pm
FSD
- STL
1 stop24h 05m
Frontier
Deal found 5/9![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:02 pm
FSD
- STL
1 stop28h 55m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:19 am
FSD
- STL
1 stop12h 44m
American Airlines
Deal found 5/11![American Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:39 pm
FSD
- STL
2 stops27h 44m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$232
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:34 pm
FSD
- STL
1 stop6h 24m
American Airlines
Deal found 5/11![American Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:36 pm
FSD
- STL
3 stops47h 01m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 pm
FSD
- STL
3 stops43h 39m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am
FSD
- STL
2 stops9h 38m
United Airlines
Deal found 5/11![United Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:07 pm
FSD
- STL
2 stops9h 22m
American Airlines
Deal found 5/11![American Airlines logo]()
$596
Find flight deals from Sioux Falls to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $280 (American Airlines) |
One-way from | $115 (Mytrip) |
Popular in | July |
Cheapest in | September |
Average price | $303 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 6/26
6:51 pm-11:57 pm
1 stop5h 06m
Lambert-St Louis
Sun 7/5
5:33 pm-11:31 pm
1 stop5h 58m
$299
Quickest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 8/21
11:05 am-3:10 pm
1 stop4h 05m
Lambert-St Louis
Tue 8/25
6:20 am-10:20 am
1 stop4h 00m
$302
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 7/11
7:40 am-12:11 pm
1 stop4h 31m
Lambert-St Louis
Mon 7/13
7:05 pm-11:31 pm
1 stop4h 26m
$339
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 8/12
11:25 am-4:34 pm
1 stop5h 09m
Lambert-St Louis
Sat 8/15
5:59 pm-10:52 pm
1 stop4h 53m
$341
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 5/28
5:35 pm-11:59 pm
1 stop6h 24m
Lambert-St Louis
Mon 6/1
9:41 am-4:55 pm
1 stop7h 14m
$385
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 6/15
5:35 pm-11:59 pm
1 stop6h 24m
Lambert-St Louis
Mon 6/22
9:09 am-4:10 pm
1 stop7h 01m
$394
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 6/26
5:35 pm-11:59 pm
1 stop6h 24m
Lambert-St Louis
Sun 7/5
6:55 am-11:35 am
1 stop4h 40m
$399
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 6/6
5:35 pm-11:59 pm
1 stop6h 24m
Lambert-St Louis
Fri 6/12
9:09 am-4:10 pm
1 stop7h 01m
$399
Cheapest one-way
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 5/27
7:18 pm-7:23 pm
1 stop24h 05m
$115
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sun 5/31
7:02 pm-11:57 pm
1 stop28h 55m
$197
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to St. Louis in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.
FSD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to St. Louis
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What is the cheapest month to book a flight from Sioux Falls to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Sioux Falls to St. Louis (average of $278). Flying from Sioux Falls to St. Louis in July is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to St. Louis?
What’s the top layover airport for flights from Sioux Falls to St. Louis?
Share of 1-stop round-trip flights from Sioux Falls to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Sioux Falls to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Sioux Falls to St. Louis?
Average round-trip fare for 1-stop flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $278.
What’s the fastest layover option from Sioux Falls to St. Louis?
Shortest average travel time for 1-stop one-way flights from Sioux Falls to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 4h 24m.
Which airport typically offers the quickest layover for flights from Sioux Falls to St. Louis?
Average layover duration for 1-stop one-way flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Denver (DEN) offer the fastest connection on this route, with an average layover time of 1h 01m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 12, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Sioux Falls and St. Louis flights
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Top 3 airlines flying from Sioux Falls to St. Louis
Discover the top 3 airlines that operate flights from Sioux Falls to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$333 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$314 | FlexibilityNo cancel fee | On-time69% |