$260+ Cheap flights from Sioux Falls (FSD) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to MissouriExplore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:50 pm -
1 stop4h 50m
Sat 9/129:00 am -
1 stop7h 33m
Deal found 9/1![United Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:56 pm -
1 stop5h 08m
Tue 10/611:31 am -
2 stops9h 42m
Deal found 9/1![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop5h 08m
Tue 10/65:00 am -
1 stop6h 34m
Deal found 9/1![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:18 pm -
1 stop4h 41m
Sun 11/88:15 pm -
1 stop4h 14m
Deal found 9/2![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm -
1 stop5h 25m
Sun 9/277:35 pm -
1 stop4h 54m
Deal found 9/2![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:31 pm -
1 stop5h 00m
Mon 10/261:40 pm -
1 stop6h 24m
Deal found 9/5![United Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:56 pm -
1 stop6h 11m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/31![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:59 pm -
1 stop5h 25m
Tue 9/221:03 pm -
1 stop6h 39m
Deal found 8/31![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:56 pm -
1 stop6h 11m
Sun 9/135:43 am -
1 stop6h 33m
Deal found 9/1![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:31 pm -
1 stop4h 47m
Mon 10/126:25 pm -
1 stop4h 46m
Deal found 9/2![United Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:50 pm -
1 stop4h 52m
Wed 9/305:30 am -
1 stop5h 20m
Deal found 9/2![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:32 am -
1 stop6h 49m
Sat 11/141:25 pm -
1 stop6h 39m
Deal found 9/5![United Airlines logo]()
$361
Best flights from Sioux Falls to MissouriDiscover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/137:40 am -
1 stop4h 33m
Sat 1/163:00 pm -
1 stop5h 46m
Deal found 9/3![United Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop5h 08m
Tue 10/65:00 am -
1 stop6h 34m
Deal found 9/1![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:31 am -
1 stop3h 46m
Mon 11/303:30 pm -
1 stop3h 36m
Deal found 9/2![Delta logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm -
1 stop5h 25m
Sun 9/277:35 pm -
1 stop4h 54m
Deal found 9/2![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:31 pm -
1 stop5h 00m
Mon 10/261:40 pm -
1 stop6h 24m
Deal found 9/5![United Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:00 pm -
2 stops32h 32m
Sat 11/1411:38 am -
1 stop23h 32m
Deal found 9/5![Multiple Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:56 pm -
1 stop6h 11m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/31![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:35 am -
1 stop6h 59m
Sun 9/206:55 pm -
1 stop4h 49m
Deal found 9/1![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:59 pm -
1 stop5h 25m
Tue 9/221:03 pm -
1 stop6h 39m
Deal found 8/31![American Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 pm -
1 stop6h 24m
Sun 11/226:00 am -
1 stop4h 20m
Deal found 9/4![Delta logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:20 pm -
1 stop7h 39m
Sat 10/311:40 pm -
1 stop6h 24m
Deal found 9/3![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:59 pm -
1 stop5h 44m
Fri 9/255:18 pm -
1 stop7h 11m
Deal found 9/3![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:32 am -
1 stop6h 49m
Sat 11/141:25 pm -
1 stop6h 39m
Deal found 9/5![United Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:31 pm -
1 stop4h 47m
Sat 10/36:25 pm -
1 stop4h 46m
Deal found 9/3![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:54 pm -
1 stop5h 29m
Mon 10/127:21 pm -
1 stop5h 20m
Deal found 9/5![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:50 pm -
1 stop4h 52m
Sun 9/205:30 am -
1 stop5h 14m
Deal found 9/5![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:04 pm -
1 stop6h 11m
Wed 9/301:48 pm -
1 stop6h 32m
Deal found 8/31![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:32 am -
1 stop6h 39m
Sun 11/85:45 am -
1 stop4h 42m
Deal found 9/4![United Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop6h 37m
Mon 9/217:11 pm -
1 stop4h 33m
Deal found 9/2![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop4h 59m
Sun 9/207:51 pm -
1 stop4h 38m
Deal found 9/3![American Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:05 pm -
1 stop6h 25m
Tue 9/225:13 pm -
1 stop6h 31m
Deal found 9/2![United Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:50 pm -
2 stops21h 16m
Sun 9/276:25 pm -
1 stop4h 46m
Deal found 9/5![United Airlines logo]()
$758
Last-minute flights from Sioux Falls to MissouriDiscover last-minute flight deals from Sioux Falls to Missouri. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Missouri. Data last updated September 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:56 pm -
1 stop6h 11m
Sun 9/135:43 am -
1 stop6h 33m
Deal found 9/1![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:50 pm -
1 stop4h 50m
Sat 9/129:00 am -
1 stop7h 33m
Deal found 9/1![United Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:56 pm -
1 stop5h 08m
Tue 10/611:31 am -
2 stops9h 42m
Deal found 9/1![American Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:50 pm -
1 stop4h 52m
Wed 9/305:30 am -
1 stop5h 20m
Deal found 9/2![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:59 pm -
1 stop5h 25m
Tue 9/221:03 pm -
1 stop6h 39m
Deal found 8/31![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:56 pm -
1 stop6h 11m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/31![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm -
1 stop5h 25m
Sun 9/277:35 pm -
1 stop4h 54m
Deal found 9/2![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:04 pm -
1 stop6h 11m
Wed 9/301:48 pm -
1 stop6h 32m
Deal found 9/1![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop5h 08m
Tue 10/65:00 am -
1 stop6h 34m
Deal found 9/1![American Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
1 stop6h 40m
Sat 10/36:25 pm -
1 stop4h 46m
Deal found 9/1![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:31 pm -
1 stop4h 47m
Mon 10/126:25 pm -
1 stop4h 46m
Deal found 9/2![United Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:31 pm -
1 stop5h 00m
Mon 10/261:40 pm -
1 stop6h 24m
Deal found 9/5![United Airlines logo]()
$310
One-way flights from Sioux Falls to MissouriSearch for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
Search for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:02 pm -
3 stops45h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$260
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:41 pm -
1 stop5h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:55 pm -
1 stop5h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:56 pm -
2 stops11h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:35 am -
1 stop6h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:28 pm -
2 stops30h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:02 pm -
2 stops21h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:05 pm -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:41 pm -
1 stop5h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:48 pm -
3 stops45h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:02 pm -
2 stops21h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:06 pm -
2 stops31h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$388
Find flight deals from Sioux Falls to Missouri
Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $276 (United Airlines) |
One-way from | $260 (Kiwi.com) |
Popular in | May |
Cheapest in | December |
Average price | $388 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Thu 9/24
6:41 pm-12:27 am
1 stop5h 46m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
Quickest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 9/23
7:47 am-11:57 am
1 stop4h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 10/7
12:53 pm-7:48 pm
1 stop6h 55m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
Sioux FallsKansas City
FSD Sioux Falls Joe Foss Field - MCI Kansas City
FSDMCI
Sioux Falls Joe Foss Field
Thu 10/1
5:55 pm-11:24 pm
1 stop5h 29m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Sat 10/24
12:58 pm-7:15 pm
3 stops54h 17m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$269
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 9/23
12:56 pm-12:27 am
2 stops11h 31m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$269
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 1/13
7:40 am-12:13 pm
1 stop4h 33m
Lambert-St Louis
Sat 1/16
3:00 pm-8:46 pm
1 stop5h 46m
$276
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Tue 9/29
12:56 pm-6:04 pm
1 stop5h 08m
Lambert-St Louis
Tue 10/6
5:00 am-11:34 am
1 stop6h 34m
$290
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Thu 9/24
10:02 pm-7:17 pm
2 stops21h 15m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$291
Sioux FallsKansas City
FSD Sioux Falls Joe Foss Field - MCI Kansas City
FSDMCI
Sioux Falls Joe Foss Field
Fri 9/25
5:59 pm-11:24 pm
1 stop5h 25m
Kansas City
Sun 9/27
7:35 pm-12:29 am
1 stop4h 54m
$299
Showing 1-10 of 34 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
FSD-STL
FSD-MCI
FSD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Missouri
FSD-USMO
FSD-STL
FSD-MCI
FSD-SGF
What is the cheapest month to book a flight from Sioux Falls to Missouri?
Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $297). Flying from Sioux Falls to Missouri in May is currently the most expensive (average of $696). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 5, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
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Sioux Falls and Missouri flights
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Top 3 airlines flying from Sioux Falls to Missouri
Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$192 | Average$337 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$243 | Average$348 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$249 | Average$388 | FlexibilityNo cancel fee | On-timeN/A |