$259+ Cheap flights from Sioux Falls (FSD) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — MCI
Aug 21 — Aug 281
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to MissouriExplore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop4h 18m
United Airlines
Tue 9/224:40 pm
STL
- FSD
1 stop7h 04m
United Airlines
Deal found 7/21![United Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop5h 46m
American Airlines
Tue 9/2211:01 am
STL
- FSD
2 stops8h 41m
American Airlines
Deal found 7/19![American Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:08 pm
FSD
- MCI
1 stop16h 52m
Frontier
Fri 8/211:38 pm
MCI
- FSD
1 stop6h 23m
Frontier
Deal found 7/16![Frontier logo]()
$278
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- STL
1 stop6h 54m
United Airlines
Sat 8/225:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:57 pm
FSD
- STL
2 stops11h 01m
American Airlines
Sat 8/225:13 pm
STL
- FSD
1 stop7h 17m
American Airlines
Deal found 7/18![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm
FSD
- STL
1 stop5h 44m
American Airlines
Sun 9/275:43 am
STL
- FSD
1 stop6h 33m
American Airlines
Deal found 7/19![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:05 am
FSD
- MCI
1 stop3h 27m
Delta
Sun 9/136:20 am
MCI
- FSD
1 stop3h 59m
Delta
Deal found 7/20![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop5h 46m
American Airlines
Mon 9/2111:01 am
STL
- FSD
1 stop13h 28m
American Airlines
Deal found 7/21![American Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:05 pm
FSD
- STL
1 stop3h 42m
Delta
Mon 9/215:47 pm
STL
- FSD
1 stop5h 04m
Delta
Deal found 7/17![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:57 pm
FSD
- STL
2 stops11h 17m
American Airlines
Sat 8/225:00 am
STL
- FSD
1 stop6h 36m
American Airlines
Deal found 7/20![American Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:39 pm
FSD
- STL
1 stop4h 19m
American Airlines
Sat 10/3111:31 am
STL
- FSD
2 stops9h 42m
American Airlines
Deal found 7/19![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:50 pm
FSD
- MCI
1 stop4h 40m
United Airlines
Mon 8/175:08 pm
MCI
- FSD
1 stop6h 14m
United Airlines
Deal found 7/20![United Airlines logo]()
$359
Best flights from Sioux Falls to MissouriDiscover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
Discover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:10 am
FSD
- STL
1 stop3h 53m
Delta
Sat 10/3111:10 am
STL
- FSD
1 stop4h 49m
Delta
Deal found 7/17![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm
FSD
- STL
1 stop4h 18m
United Airlines
Tue 9/224:40 pm
STL
- FSD
1 stop7h 04m
United Airlines
Deal found 7/21![United Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:08 pm
FSD
- MCI
1 stop16h 52m
Frontier
Fri 8/211:38 pm
MCI
- FSD
1 stop6h 23m
Frontier
Deal found 7/16![Frontier logo]()
$278
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:23 pm
FSD
- STL
1 stop6h 51m
American Airlines
Sat 8/228:06 pm
STL
- FSD
1 stop4h 24m
American Airlines
Deal found 7/20![American Airlines logo]()
$280
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:33 pm
FSD
- STL
1 stop7h 05m
United Airlines
Mon 9/216:53 pm
STL
- FSD
1 stop4h 19m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:09 pm
FSD
- STL
2 stops10h 49m
American Airlines
Sun 12/67:29 am
STL
- FSD
1 stop6h 49m
American Airlines
Deal found 7/19![American Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:05 am
FSD
- MCI
1 stop3h 27m
Delta
Sun 9/136:20 am
MCI
- FSD
1 stop3h 59m
Delta
Deal found 7/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- STL
1 stop6h 54m
United Airlines
Sat 8/225:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm
FSD
- STL
1 stop5h 44m
American Airlines
Sun 9/275:43 am
STL
- FSD
1 stop6h 33m
American Airlines
Deal found 7/19![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:05 pm
FSD
- STL
1 stop3h 42m
Delta
Mon 9/215:47 pm
STL
- FSD
1 stop5h 04m
Delta
Deal found 7/20![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:55 pm
FSD
- MCI
1 stop5h 29m
American Airlines
Sat 9/125:28 am
MCI
- FSD
1 stop6h 48m
American Airlines
Deal found 7/19![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:10 am
FSD
- STL
1 stop5h 33m
United Airlines
Sat 10/315:00 am
STL
- FSD
1 stop5h 32m
United Airlines
Deal found 7/21![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:57 pm
FSD
- STL
1 stop5h 08m
American Airlines
Mon 8/103:32 pm
STL
- FSD
1 stop4h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
FSD
- MCI
1 stop6h 37m
United Airlines
Mon 8/241:43 pm
MCI
- FSD
1 stop6h 24m
United Airlines
Deal found 7/19![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:50 pm
FSD
- MCI
1 stop4h 40m
United Airlines
Mon 8/175:08 pm
MCI
- FSD
1 stop6h 14m
United Airlines
Deal found 7/19![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am
FSD
- MCI
1 stop4h 51m
United Airlines
Mon 8/246:00 am
MCI
- FSD
1 stop4h 43m
United Airlines
Deal found 7/21![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
FSD
- SGF
1 stop4h 43m
United Airlines
Mon 8/176:37 pm
SGF
- FSD
1 stop4h 45m
United Airlines
Deal found 7/17![United Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:31 pm
FSD
- SGF
1 stop14h 37m
American Airlines
Sun 11/1510:38 am
SGF
- FSD
1 stop8h 23m
American Airlines
Deal found 7/19![American Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:41 pm
FSD
- SGF
1 stop4h 40m
United Airlines
Sun 9/205:30 am
SGF
- FSD
1 stop5h 14m
United Airlines
Deal found 7/20![United Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:05 pm
FSD
- SGF
2 stops9h 03m
Delta
Sun 9/2011:37 am
SGF
- FSD
2 stops8h 06m
Delta
Deal found 7/19![Delta logo]()
$1,431
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:26 pm
FSD
- SGF
2 stops8h 55m
Delta
Tue 8/116:06 am
SGF
- FSD
2 stops9h 42m
Delta
Deal found 7/17![Delta logo]()
$1,441
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:00 am
FSD
- SGF
2 stops9h 38m
Delta
Mon 8/176:06 am
SGF
- FSD
2 stops9h 42m
Delta
Deal found 7/17![Delta logo]()
$1,451
Last-minute flights from Sioux Falls to MissouriDiscover last-minute flight deals from Sioux Falls to Missouri. Data last updated July 22, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Missouri. Data last updated July 22, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:28 pm
FSD
- SGF
1 stop4h 59m
United Airlines
Mon 8/36:34 pm
SGF
- FSD
1 stop4h 57m
United Airlines
Deal found 7/17![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:05 pm
FSD
- STL
1 stop6h 52m
United Airlines
Sun 8/96:00 am
STL
- FSD
1 stop4h 41m
United Airlines
Deal found 7/21![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:28 pm
FSD
- STL
1 stop5h 01m
United Airlines
Tue 8/111:36 pm
STL
- FSD
1 stop6h 31m
United Airlines
Deal found 7/19![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
FSD
- SGF
1 stop4h 43m
United Airlines
Mon 8/176:37 pm
SGF
- FSD
1 stop4h 45m
United Airlines
Deal found 7/17![United Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:08 pm
FSD
- MCI
1 stop16h 52m
Frontier
Fri 8/211:38 pm
MCI
- FSD
1 stop6h 23m
Frontier
Deal found 7/16![Frontier logo]()
$278
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:50 pm
FSD
- MCI
1 stop4h 40m
United Airlines
Mon 8/175:08 pm
MCI
- FSD
1 stop6h 14m
United Airlines
Deal found 7/20![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- STL
1 stop6h 54m
United Airlines
Sat 8/225:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/18![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:57 pm
FSD
- STL
2 stops11h 01m
American Airlines
Sat 8/225:13 pm
STL
- FSD
1 stop7h 17m
American Airlines
Deal found 7/18![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:57 pm
FSD
- STL
1 stop6h 54m
American Airlines
Sun 8/238:07 pm
STL
- FSD
1 stop4h 18m
American Airlines
Deal found 7/18![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:57 pm
FSD
- STL
2 stops11h 17m
American Airlines
Sat 8/225:00 am
STL
- FSD
1 stop6h 36m
American Airlines
Deal found 7/20![American Airlines logo]()
$320
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:47 am
FSD
- STL
1 stop7h 10m
United Airlines
Wed 8/265:30 pm
STL
- FSD
1 stop5h 52m
United Airlines
Deal found 7/19![United Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:57 pm
FSD
- STL
2 stops11h 17m
American Airlines
Mon 8/313:32 pm
STL
- FSD
1 stop4h 59m
American Airlines
Deal found 7/19![American Airlines logo]()
$399
One-way flights from Sioux Falls to MissouriSearch for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
Search for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:56 pm
FSD
- STL
1 stop5h 08m
American Airlines
Deal found 7/18![American Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:58 pm
FSD
- STL
3 stops44h 42m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$261
This deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:12 am
FSD
- STL
1 stop4h 26m
United Airlines
Deal found 7/19![United Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:08 pm
FSD
- MCI
2 stops19h 39m
Frontier
Deal found 7/20![Frontier logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:36 pm
FSD
- MCI
1 stop24h 11m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:00 pm
FSD
- MCI
1 stop25h 07m
Allegiant Air
Deal found 7/20![Allegiant Air logo]()
$367
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:23 am
FSD
- MCI
1 stop3h 23m
Delta
Deal found 7/20![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:35 am
FSD
- STL
1 stop4h 36m
United Airlines
Deal found 7/21![United Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:39 pm
FSD
- MCI
2 stops39h 21m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:36 pm
FSD
- STL
2 stops23h 39m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:00 pm
FSD
- MCI
3 stops44h 00m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:00 pm
FSD
- MCI
2 stops10h 17m
United Airlines
Deal found 7/20![United Airlines logo]()
$772
Find flight deals from Sioux Falls to Missouri
Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated July 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (United Airlines) |
One-way from | $259 (American Airlines) |
Popular in | September |
Cheapest in | July |
Average price | $288 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 10/28
5:10 am-9:03 am
1 stop3h 53m
Lambert-St Louis
Sat 10/31
11:10 am-3:59 pm
1 stop4h 49m
$271
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 9/19
6:41 pm-10:59 pm
1 stop4h 18m
Lambert-St Louis
Tue 9/22
4:40 pm-11:44 pm
1 stop7h 04m
$271
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Fri 8/14
8:08 pm-1:00 pm
1 stop16h 52m
Kansas City
Fri 8/21
1:38 pm-8:01 pm
1 stop6h 23m
$278
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 8/20
5:23 pm-12:14 am
1 stop6h 51m
Lambert-St Louis
Sat 8/22
8:06 pm-12:30 am
1 stop4h 24m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 9/19
1:33 pm-8:38 pm
1 stop7h 05m
Lambert-St Louis
Mon 9/21
6:53 pm-11:12 pm
1 stop4h 19m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 8/15
3:06 pm-10:00 pm
1 stop6h 54m
Lambert-St Louis
Sat 8/22
5:30 pm-11:22 pm
1 stop5h 52m
$280
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 12/2
1:09 pm-11:58 pm
2 stops10h 49m
Lambert-St Louis
Sun 12/6
7:29 am-2:18 pm
1 stop6h 49m
$285
Quickest round-trip
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 9/10
5:05 am-8:32 am
1 stop3h 27m
Kansas City
Sun 9/13
6:20 am-10:19 am
1 stop3h 59m
$289
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 9/25
5:59 pm-11:43 pm
1 stop5h 44m
Lambert-St Louis
Sun 9/27
5:43 am-12:16 pm
1 stop6h 33m
$289
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 9/10
5:55 pm-11:24 pm
1 stop5h 29m
Kansas City
Sat 9/12
5:28 am-12:16 pm
1 stop6h 48m
$289
Showing 1-10 of 33 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
FSD-STL
FSD-MCI
FSD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Missouri
FSD-USMO
FSD-STL
FSD-MCI
FSD-SGF
What is the cheapest month to book a flight from Sioux Falls to Missouri?
Currently, July is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $288). Flying from Sioux Falls to Missouri in September is currently the most expensive (average of $837). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 22, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Sioux Falls and Missouri flights
Browse other Sioux Falls and Missouri flight options. Last updated on July 22, 2026.
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Sioux Falls to Missouri flights
Consider these flights traveling from Sioux Falls to Missouri.
Top 3 airlines flying from Sioux Falls to Missouri
Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$243 | Average$335 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$249 | Average$379 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$337 | FlexibilityNo cancel fee | On-time69% |