$105+ Cheap flights from Sioux Falls to San Francisco (FSD - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — SFO
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to San Francisco
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Cheapest flights from Sioux Falls to San FranciscoExplore the most affordable flight options available from Sioux Falls to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Sioux Falls to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:18 pm
FSD
- SFO
1 stop7h 05m
Frontier
Wed 6/38:56 am
SFO
- FSD
1 stop7h 37m
Frontier
Deal found 5/4![Frontier logo]()
$230
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:07 pm
FSD
- SFO
1 stop10h 16m
Frontier
Mon 5/186:00 am
SFO
- FSD
1 stop7h 22m
Frontier
Deal found 5/1![Frontier logo]()
$231
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:14 pm
FSD
- SFO
1 stop6h 04m
Frontier
Fri 7/246:00 am
SFO
- FSD
1 stop11h 23m
Frontier
Deal found 5/5![Frontier logo]()
$250
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:14 pm
FSD
- SFO
1 stop6h 04m
Frontier
Mon 8/246:00 am
SFO
- FSD
1 stop11h 19m
Frontier
Deal found 5/4![Frontier logo]()
$264
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:18 pm
FSD
- SFO
1 stop7h 05m
Frontier
Fri 6/56:00 am
SFO
- FSD
1 stop7h 40m
Frontier
Deal found 5/4![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:42 pm
FSD
- SFO
1 stop21h 53m
Multiple Airlines
Tue 6/93:26 pm
SFO
- FSD
2 stops25h 53m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:53 pm
FSD
- SFO
2 stops48h 43m
Multiple Airlines
Thu 7/97:11 pm
SFO
- FSD
1 stop22h 39m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:42 pm
FSD
- SFO
2 stops24h 53m
Multiple Airlines
Tue 6/1610:58 pm
SFO
- FSD
1 stop13h 48m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/103:36 pm
FSD
- SFO
1 stop19h 15m
Multiple Airlines
Tue 6/1610:58 pm
SFO
- FSD
1 stop13h 48m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$291
Best flights from Sioux Falls to San FranciscoDiscover carefully curated flight deals from Sioux Falls to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Sioux Falls to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:22 am
FSD
- SFO
1 stop6h 47m
Delta
Sat 8/156:06 am
SFO
- FSD
1 stop7h 42m
Delta
Deal found 5/5![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:51 pm
FSD
- SFO
1 stop6h 05m
United Airlines
Sun 5/246:15 am
SFO
- FSD
1 stop8h 08m
United Airlines
Deal found 5/1![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:25 pm
FSD
- SFO
2 stops8h 18m
American Airlines
Mon 10/2611:56 pm
SFO
- FSD
1 stop9h 30m
American Airlines
Deal found 5/2![American Airlines logo]()
$462
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:12 am
FSD
- SFO
1 stop8h 23m
Delta
Wed 7/86:00 am
SFO
- FSD
1 stop7h 41m
Delta
Deal found 5/5![Delta logo]()
$311
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:00 pm
FSD
- SFO
1 stop9h 22m
Delta
Wed 10/283:00 pm
SFO
- FSD
1 stop5h 51m
Delta
Deal found 5/2![Delta logo]()
$320
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:51 pm
FSD
- SFO
1 stop6h 05m
United Airlines
Sat 5/232:20 pm
SFO
- FSD
1 stop7h 33m
United Airlines
Deal found 5/1![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:28 pm
FSD
- SFO
1 stop7h 41m
American Airlines
Wed 5/279:04 am
SFO
- FSD
2 stops11h 13m
American Airlines
Deal found 5/2![American Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:04 am
FSD
- SFO
1 stop8h 24m
Delta
Mon 8/248:59 pm
SFO
- FSD
2 stops11h 21m
Delta
Deal found 5/4![Delta logo]()
$447
Last-minute flights from Sioux Falls to San FranciscoDiscover last-minute flight deals from Sioux Falls to San Francisco. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to San Francisco. Data last updated May 6, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:07 pm
FSD
- SFO
1 stop10h 16m
Frontier
Mon 5/186:00 am
SFO
- FSD
1 stop7h 22m
Frontier
Deal found 5/1![Frontier logo]()
$231
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:18 pm
FSD
- SFO
1 stop7h 05m
Frontier
Wed 6/38:56 am
SFO
- FSD
1 stop7h 37m
Frontier
Deal found 5/4![Frontier logo]()
$230
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:18 pm
FSD
- SFO
1 stop7h 05m
Frontier
Fri 6/56:00 am
SFO
- FSD
1 stop7h 40m
Frontier
Deal found 5/4![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:53 pm
FSD
- SFO
2 stops48h 43m
Multiple Airlines
Thu 7/97:11 pm
SFO
- FSD
1 stop22h 39m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:42 pm
FSD
- SFO
1 stop21h 53m
Multiple Airlines
Tue 6/93:26 pm
SFO
- FSD
2 stops25h 53m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:42 pm
FSD
- SFO
2 stops24h 53m
Multiple Airlines
Tue 6/1610:58 pm
SFO
- FSD
1 stop13h 48m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/103:36 pm
FSD
- SFO
1 stop19h 15m
Multiple Airlines
Tue 6/1610:58 pm
SFO
- FSD
1 stop13h 48m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:42 pm
FSD
- SFO
1 stop21h 39m
Multiple Airlines
Tue 6/1610:58 pm
SFO
- FSD
1 stop13h 48m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$295
One-way flights from Sioux Falls to San FranciscoSearch for one-way flight options from Sioux Falls to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Sioux Falls to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This Priceline deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:18 pm
FSD
- SFO
1 stop7h 05m
Frontier
Deal found 5/5![Frontier logo]()
$105
This Priceline deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:14 pm
FSD
- SFO
1 stop6h 08m
Frontier
Deal found 5/5![Frontier logo]()
$125
This Trip.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:25 pm
FSD
- SFO
1 stop17h 36m
Frontier
Deal found 5/1![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:36 pm
FSD
- SFO
2 stops30h 00m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:01 pm
FSD
- SFO
2 stops30h 56m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:56 pm
FSD
- SFO
1 stop29h 25m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$178
This Priceline deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:07 pm
FSD
- SFO
1 stop10h 16m
Frontier
Deal found 5/6![Frontier logo]()
$191
Find flight deals from Sioux Falls to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Frontier) |
One-way from | $105 (Priceline) |
Popular in | February |
Cheapest in | September |
Average price | $331 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Sioux Falls to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Wed 8/12
8:22 am-1:09 pm
1 stop6h 47m
San Francisco
Sat 8/15
6:06 am-3:48 pm
1 stop7h 42m
$311
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Fri 7/3
5:12 am-11:35 am
1 stop8h 23m
San Francisco
Wed 7/8
6:00 am-3:41 pm
1 stop7h 41m
$311
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Fri 10/23
1:00 pm-8:22 pm
1 stop9h 22m
San Francisco
Wed 10/28
3:00 pm-10:51 pm
1 stop5h 51m
$320
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Fri 5/22
6:51 pm-10:56 pm
1 stop6h 05m
San Francisco
Sun 5/24
6:15 am-4:23 pm
1 stop8h 08m
$389
Quickest round-trip
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Fri 5/22
6:51 pm-10:56 pm
1 stop6h 05m
San Francisco
Sat 5/23
2:20 pm-11:53 pm
1 stop7h 33m
$412
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Mon 8/17
5:04 am-11:28 am
1 stop8h 24m
San Francisco
Mon 8/24
8:59 pm-10:20 am
2 stops11h 21m
$447
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Wed 10/21
12:25 pm-6:43 pm
2 stops8h 18m
San Francisco
Mon 10/26
11:56 pm-11:26 am
1 stop9h 30m
$462
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Tue 5/19
5:28 pm-11:09 pm
1 stop7h 41m
San Francisco
Wed 5/27
9:04 am-10:17 pm
2 stops11h 13m
$469
Cheapest one-way
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Wed 6/3
3:36 pm-7:36 pm
2 stops30h 00m
$141
Sioux FallsSan Francisco
FSD - SFO
FSDSFO
Sioux Falls Joe Foss Field
Sat 5/23
1:01 pm-5:57 pm
2 stops30h 56m
$168
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to San Francisco in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sioux Falls with our price prediction graph.
FSD-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to San Francisco
What is the cheapest month to book a flight from Sioux Falls to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Sioux Falls to San Francisco (average of $281). Flying from Sioux Falls to San Francisco in February is currently the most expensive (average of $588). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 6, 2026.
Read through reviews of airlines operating flights from Sioux Falls to San Francisco, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
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Sioux Falls and San Francisco flights
Browse other Sioux Falls and San Francisco flight options. Last updated on May 6, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Top 3 airlines flying from Sioux Falls to San Francisco
Discover the top 3 airlines that operate flights from Sioux Falls to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$246 | Average$293 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$437 | FlexibilityNo cancel fee | On-time69% |