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Mississippi

$269+ Cheap flights from Sioux Falls (FSD) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Aug 22 — Aug 291
Sat 8/22
Sat 8/29
1 adult, Economy
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Cheap flight deals from Sioux Falls to Mississippi

Cheapest flights from Sioux Falls to Mississippi
Explore the most affordable flight options available from Sioux Falls to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.

This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:06 pm
FSD
-
JAN
1 stop4h 53m
American Airlines
Mon 8/245:30 am
JAN
-
FSD
1 stop6h 47m
American Airlines
Deal found 7/21$309
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:06 pm
FSD
-
MEM
1 stop4h 44m
American Airlines
Thu 8/207:13 am
MEM
-
FSD
1 stop5h 04m
American Airlines
Deal found 7/21$309
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:47 am
FSD
-
MEM
2 stops10h 29m
United Airlines
Mon 8/246:31 pm
MEM
-
FSD
1 stop4h 51m
United Airlines
Deal found 7/20$314
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:15 am
FSD
-
JAN
2 stops8h 52m
Delta
Sat 11/145:45 am
JAN
-
FSD
2 stops10h 05m
Delta
Deal found 7/19$319
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:06 pm
FSD
-
MOB
1 stop4h 53m
American Airlines
Sun 8/235:30 am
MOB
-
FSD
1 stop6h 47m
American Airlines
Deal found 7/19$319
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:00 am
FSD
-
JAN
2 stops9h 44m
Delta
Mon 8/241:00 pm
JAN
-
FSD
1 stop6h 59m
Delta
Deal found 7/21$324
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:22 am
FSD
-
MOB
2 stops9h 46m
Delta
Sun 8/2312:06 pm
MOB
-
FSD
1 stop7h 53m
Delta
Deal found 7/20$324
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:57 pm
FSD
-
GPT
1 stop5h 04m
American Airlines
Tue 8/255:31 am
GPT
-
FSD
1 stop6h 46m
American Airlines
Deal found 7/21$339
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:30 am
FSD
-
MOB
1 stop5h 52m
Delta
Tue 9/2212:10 pm
MOB
-
FSD
1 stop7h 37m
Delta
Deal found 7/20$344
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:47 am
FSD
-
JAN
2 stops8h 38m
United Airlines
Mon 8/242:05 pm
JAN
-
FSD
2 stops9h 17m
United Airlines
Deal found 7/21$346
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:25 am
FSD
-
MOB
1 stop6h 08m
Delta
Thu 11/269:10 am
MOB
-
FSD
2 stops6h 40m
Delta
Deal found 7/20$349
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
FSD
-
JAN
1 stop5h 44m
American Airlines
Sat 11/147:00 am
JAN
-
FSD
1 stop5h 28m
American Airlines
Deal found 7/19$354

Find flight deals from Sioux Falls to Mississippi

Keep the following information in mind while searching for Sioux Falls to Mississippi flight deals. Data was last updated July 23, 2026.

Round-trip from

$309
(American Airlines)

One-way from

$269
(Delta)
From Sioux Falls Joe Foss Field to Mississippi
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Sioux Falls to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Sat 8/15

6:06 pm-10:50 pm

1 stop4h 44m

Memphis

Thu 8/20

7:13 am-12:17 pm

1 stop5h 04m

$309

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Tue 8/18

7:47 am-6:16 pm

2 stops10h 29m

Memphis

Mon 8/24

6:31 pm-11:22 pm

1 stop4h 51m

$314

Sioux FallsJackson

FSD - JAN

FSDJAN

Sioux Falls Joe Foss Field

Wed 11/11

5:15 am-2:07 pm

2 stops8h 52m

Jackson-Evers Intl

Sat 11/14

5:45 am-3:50 pm

2 stops10h 05m

$319

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Fri 8/14

6:06 pm-10:59 pm

1 stop4h 53m

Mobile

Sun 8/23

5:30 am-12:17 pm

1 stop6h 47m

$319

Sioux FallsJackson

FSD - JAN

FSDJAN

Sioux Falls Joe Foss Field

Wed 1/6

5:25 am-11:22 am

1 stop5h 57m

Jackson-Evers Intl

Sat 1/9

7:45 am-3:50 pm

2 stops8h 05m

$324

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Fri 8/14

8:22 am-6:08 pm

2 stops9h 46m

Mobile

Sun 8/23

12:06 pm-7:59 pm

1 stop7h 53m

$324

Sioux FallsGulfport

FSD - GPT

FSDGPT

Sioux Falls Joe Foss Field

Thu 8/20

12:57 pm-6:01 pm

1 stop5h 04m

Gulfport Biloxi Regional

Sun 8/23

5:31 am-12:17 pm

1 stop6h 46m

$339

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Thu 9/17

5:30 am-11:22 am

1 stop5h 52m

Mobile

Tue 9/22

12:10 pm-7:47 pm

1 stop7h 37m

$344

Sioux FallsJackson

FSD - JAN

FSDJAN

Sioux Falls Joe Foss Field

Wed 11/11

6:00 am-11:44 am

1 stop5h 44m

Jackson-Evers Intl

Sat 11/14

7:00 am-12:28 pm

1 stop5h 28m

$354

Sioux FallsGulfport

FSD - GPT

FSDGPT

Sioux Falls Joe Foss Field

Wed 8/19

5:00 am-1:03 pm

2 stops8h 03m

Gulfport Biloxi Regional

Tue 8/25

1:48 pm-7:59 pm

1 stop6h 11m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/19

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Sioux Falls to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Mississippi

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 23, 2026.
Read through reviews of airlines operating flights from Sioux Falls to Mississippi, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,832 reviews

Comfort

7.2

Boarding

7.5

Food

6.4

Entertainment

6.8

Crew

7.9

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.1
Good
11,832 reviews
American Airlines
7.1
Good
11,832 reviews

Comfort

7.2

Boarding

7.5

Food

6.4

Entertainment

6.8

Crew

7.9

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Mississippi from Sioux Falls.

  • How long is the flight from Sioux Falls to Mississippi?

    Departing from Sioux Falls to Mississippi will take you 4h 44m. Airlines will cover a distance of 691 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Sioux Falls to Mississippi?

    While some choose either Sioux Falls Joe Foss Field - Mobile or Sioux Falls Joe Foss Field - Gulfport Biloxi Regional, Sioux Falls Joe Foss Field - Memphis is the most popular route from Sioux Falls to Mississippi.

  • Can I find deals for flights from Sioux Falls to Mississippi that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Mississippi.

  • Can I find deals for business class flights from Sioux Falls to Mississippi?

    Yes. Cheapflights offers flight deals from Sioux Falls to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Sioux Falls to Mississippi

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Top airline flying from Sioux Falls to Mississippi

Discover the top airline that operate flights from Sioux Falls to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$480FlexibilityNo cancel feeOn-time71%

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