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Sioux Falls

$146+ Cheap flights from Missouri to Sioux Falls (FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — FSD
May 11 — May 181
Mon 5/11
Mon 5/18
1 adult, Economy
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Cheap flight deals from Missouri to Sioux Falls

Cheapest flights from Missouri to Sioux Falls
Explore the most affordable flight options available from Missouri to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.

This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:11 pm
STL
-
FSD
1 stop4h 16m
Delta
Sat 5/169:15 am
FSD
-
STL
1 stop6h 04m
Delta
Deal found 4/9$271
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:40 am
STL
-
FSD
1 stop6h 06m
American Airlines
Mon 9/216:00 pm
FSD
-
STL
1 stop5h 20m
American Airlines
Deal found 4/8$290
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:35 pm
STL
-
FSD
1 stop5h 27m
Delta
Sun 5/38:05 am
FSD
-
STL
1 stop3h 27m
Delta
Deal found 4/10$300
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
STL
-
FSD
1 stop7h 36m
American Airlines
Wed 4/2912:29 pm
FSD
-
STL
1 stop4h 12m
American Airlines
Deal found 4/7$305
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:06 pm
MCI
-
FSD
1 stop5h 05m
American Airlines
Mon 5/117:39 pm
FSD
-
MCI
1 stop4h 37m
American Airlines
Deal found 4/6$309
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:53 pm
SGF
-
FSD
1 stop4h 17m
American Airlines
Mon 8/315:54 pm
FSD
-
SGF
1 stop6h 04m
American Airlines
Deal found 4/7$309
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:30 am
MCI
-
FSD
1 stop7h 26m
American Airlines
Sun 4/267:39 pm
FSD
-
MCI
1 stop4h 20m
American Airlines
Deal found 4/6$319
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:12 am
STL
-
FSD
1 stop5h 44m
American Airlines
Mon 4/277:39 pm
FSD
-
STL
1 stop4h 07m
American Airlines
Deal found 4/8$319
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:50 am
STL
-
FSD
2 stops7h 58m
Multiple Airlines
Fri 5/18:06 pm
FSD
-
STL
1 stop23h 26m
Multiple Airlines
Deal found 4/9$321
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:50 am
STL
-
FSD
2 stops7h 58m
Multiple Airlines
Wed 4/292:35 pm
FSD
-
STL
1 stop30h 25m
Multiple Airlines
Deal found 4/7$323
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:10 pm
MCI
-
FSD
1 stop4h 43m
United Airlines
Tue 6/165:05 pm
FSD
-
MCI
1 stop6h 20m
United Airlines
Deal found 4/9$329
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:35 pm
STL
-
FSD
1 stop4h 33m
United Airlines
Mon 6/296:50 pm
FSD
-
STL
1 stop4h 09m
United Airlines
Deal found 4/7$329

Find flight deals from Missouri to Sioux Falls

Keep the following information in mind while searching for Missouri to Sioux Falls flight deals. Data was last updated April 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Delta)

One-way from

$146
(American Airlines)

Popular in

November

Cheapest in

May

Average price

$421
Provider with most accurate pricing for Lambert-St Louis-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Sioux Falls Joe Foss Field flights.
Search Deals
From Missouri to Sioux Falls Joe Foss Field
Search Deals
One-way flight from Missouri to Sioux Falls Joe Foss Field
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Missouri to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Wed 5/13

3:11 pm-7:27 pm

1 stop4h 16m

Sioux Falls Joe Foss Field

Sat 5/16

9:15 am-3:19 pm

1 stop6h 04m

$271

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Sat 5/2

5:35 pm-11:02 pm

1 stop5h 27m

Sioux Falls Joe Foss Field

Sun 5/3

8:05 am-11:32 am

1 stop3h 27m

$300

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Fri 4/24

5:20 am-12:56 pm

1 stop7h 36m

Sioux Falls Joe Foss Field

Wed 4/29

12:29 pm-4:41 pm

1 stop4h 12m

$305

Kansas CitySioux Falls

MCI - FSD

MCIFSD

Kansas City

Fri 5/8

5:15 pm-9:52 pm

1 stop4h 37m

Sioux Falls Joe Foss Field

Sun 5/10

7:30 am-12:24 pm

1 stop4h 54m

$309

Kansas CitySioux Falls

MCI - FSD

MCIFSD

Kansas City

Mon 5/4

6:06 pm-11:11 pm

1 stop5h 05m

Sioux Falls Joe Foss Field

Mon 5/11

7:39 pm-12:16 am

1 stop4h 37m

$309

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Thu 4/23

7:12 am-12:56 pm

1 stop5h 44m

Sioux Falls Joe Foss Field

Mon 4/27

7:39 pm-11:46 pm

1 stop4h 07m

$319

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Sat 4/25

5:20 am-12:57 pm

1 stop7h 37m

Sioux Falls Joe Foss Field

Wed 4/29

6:00 am-11:37 am

1 stop5h 37m

$319

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Fri 4/24

9:50 am-5:48 pm

2 stops7h 58m

Sioux Falls Joe Foss Field

Wed 4/29

2:35 pm-9:00 pm

1 stop30h 25m

$323

Kansas CitySioux Falls

MCI - FSD

MCIFSD

Kansas City

Fri 6/12

7:10 pm-11:53 pm

1 stop4h 43m

Sioux Falls Joe Foss Field

Tue 6/16

5:05 pm-11:25 pm

1 stop6h 20m

$329
Quickest round-trip

St. LouisSioux Falls

STL - FSD

STLFSD

Lambert-St Louis

Fri 6/26

8:35 pm-1:08 am

1 stop4h 33m

Sioux Falls Joe Foss Field

Mon 6/29

6:50 pm-10:59 pm

1 stop4h 09m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/9

Showing 1-10 of 29 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sioux Falls

What is the cheapest month to book a flight from Missouri to Sioux Falls?

Currently, August is the cheapest month in which you can book a flight from Missouri to Sioux Falls (average of $197). Flying from Missouri to Sioux Falls in November is currently the most expensive (average of $514). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Sioux Falls?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Sioux Falls from Missouri?

    For a flight from Missouri to Sioux Falls, you will be flying into Joe Foss Field. Sioux Falls Joe Foss Field (FSD) is just 2.6 mi from the center of the city.

  • How long is the flight from Missouri to Sioux Falls?

    A quick flight from Missouri to Sioux Falls can take about 4h 16m. Delta provides one of the quickest options available for as low as $271. Missouri and Sioux Falls are separated by a distance of 470 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Sioux Falls?

    When deciding which route to take from Missouri to Sioux Falls consider Lambert-St Louis - Sioux Falls Joe Foss Field, Kansas City - Sioux Falls Joe Foss Field or Springfield-Branson - Sioux Falls Joe Foss Field as they are the most popular.

  • Can I find deals for flights from Missouri to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Missouri to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sioux Falls.

  • Can I find deals for business class flights from Missouri to Sioux Falls?

    Yes. Cheapflights offers flight deals from Missouri to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Sioux Falls?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Sioux Falls (average of $197). Flying from Missouri to Sioux Falls in November is currently the most expensive (average of $514). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Top 3 airlines flying from Missouri to Sioux Falls

Discover the top 3 airlines that operate flights from Missouri to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$297FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$417FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$422FlexibilityNo cancel feeOn-time69%

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