$138+ Cheap flights from Portland, ME to St. Louis (PWM - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Aug 6 — Aug 131
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:25 am
PWM
- STL
1 stop4h 25m
Southwest
Mon 9/72:20 pm
STL
- PWM
1 stop6h 10m
Southwest
Deal found 7/7![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:05 pm
PWM
- STL
1 stop6h 20m
Southwest
Fri 8/284:15 pm
STL
- PWM
1 stop5h 10m
Southwest
Deal found 7/7![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:46 pm
PWM
- STL
1 stop5h 48m
American Airlines
Sat 8/225:42 pm
STL
- PWM
1 stop4h 55m
American Airlines
Deal found 7/3![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:45 am
PWM
- STL
1 stop5h 16m
American Airlines
Sun 8/25:58 pm
STL
- PWM
1 stop5h 45m
American Airlines
Deal found 7/2![American Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
PWM
- STL
1 stop7h 02m
United Airlines
Wed 9/28:00 am
STL
- PWM
1 stop5h 34m
United Airlines
Deal found 7/2![United Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:15 am
PWM
- STL
2 stops7h 47m
United Airlines
Sun 9/208:00 am
STL
- PWM
1 stop5h 34m
United Airlines
Deal found 7/6![United Airlines logo]()
$432
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:40 pm
PWM
- STL
2 stops7h 25m
Southwest
Fri 8/2812:55 pm
STL
- PWM
2 stops8h 30m
Southwest
Deal found 7/7![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am
PWM
- STL
2 stops9h 17m
United Airlines
Sat 10/101:25 pm
STL
- PWM
2 stops9h 03m
United Airlines
Deal found 7/7![United Airlines logo]()
$402
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am
PWM
- STL
1 stop5h 51m
Delta
Wed 11/116:45 am
STL
- PWM
1 stop4h 08m
Delta
Deal found 7/4![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
PWM
- STL
1 stop7h 02m
United Airlines
Wed 9/28:00 am
STL
- PWM
1 stop5h 34m
United Airlines
Deal found 7/2![United Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:40 pm
PWM
- STL
2 stops8h 20m
Southwest
Wed 11/116:20 am
STL
- PWM
2 stops7h 30m
Southwest
Deal found 7/4![Southwest logo]()
$437
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:30 am
PWM
- STL
1 stop6h 17m
Delta
Mon 8/103:39 pm
STL
- PWM
1 stop6h 34m
Delta
Deal found 7/6![Delta logo]()
$437
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 am
PWM
- STL
2 stops13h 55m
Southwest
Sun 8/25:10 pm
STL
- PWM
1 stop6h 00m
Southwest
Deal found 7/3![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:35 am
PWM
- STL
2 stops8h 20m
Southwest
Sat 8/13:45 pm
STL
- PWM
2 stops7h 00m
Southwest
Deal found 7/5![Southwest logo]()
$513
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated July 7, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated July 7, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:30 am
PWM
- STL
1 stop7h 00m
Southwest
Tue 7/284:00 pm
STL
- PWM
1 stop4h 35m
Southwest
Deal found 7/6![Southwest logo]()
$477
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:01 pm
PWM
- STL
1 stop6h 57m
American Airlines
Sun 8/29:25 am
STL
- PWM
1 stop6h 44m
American Airlines
Deal found 7/3![American Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 am
PWM
- STL
2 stops13h 55m
Southwest
Sun 8/25:10 pm
STL
- PWM
1 stop6h 00m
Southwest
Deal found 7/3![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:45 am
PWM
- STL
1 stop5h 20m
Southwest
Mon 8/102:45 pm
STL
- PWM
2 stops6h 40m
Southwest
Deal found 7/6![Southwest logo]()
$442
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:46 pm
PWM
- STL
1 stop5h 48m
American Airlines
Sat 8/225:42 pm
STL
- PWM
1 stop4h 55m
American Airlines
Deal found 7/3![American Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:07 am
PWM
- STL
1 stop30h 04m
Multiple Airlines
Mon 8/316:17 pm
STL
- PWM
2 stops20h 42m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:30 am
PWM
- STL
2 stops8h 25m
Southwest
Mon 8/3112:15 pm
STL
- PWM
2 stops9h 10m
Southwest
Deal found 7/4![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:05 pm
PWM
- STL
1 stop6h 20m
Southwest
Fri 8/284:15 pm
STL
- PWM
1 stop5h 10m
Southwest
Deal found 7/7![Southwest logo]()
$314
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:40 pm
PWM
- STL
1 stop7h 57m
American Airlines
Deal found 7/7![American Airlines logo]()
$138
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:20 am
PWM
- STL
2 stops6h 40m
Southwest
Deal found 7/6![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:00 am
PWM
- STL
2 stops11h 22m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$158
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:46 pm
PWM
- STL
1 stop5h 48m
American Airlines
Deal found 7/2![American Airlines logo]()
$176
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
PWM
- STL
2 stops10h 43m
United Airlines
Deal found 7/7![United Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:10 pm
PWM
- STL
1 stop6h 00m
Southwest
Deal found 7/6![Southwest logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:35 am
PWM
- STL
3 stops27h 05m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:40 am
PWM
- STL
2 stops8h 45m
Southwest
Deal found 7/2![Southwest logo]()
$239
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:39 pm
PWM
- STL
1 stop5h 37m
American Airlines
Deal found 7/7![American Airlines logo]()
$254
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
PWM
- STL
1 stop7h 11m
United Airlines
Deal found 7/2![United Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:07 am
PWM
- STL
2 stops32h 08m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$278
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $272 (Southwest) |
One-way from | $138 (American Airlines) |
Popular in | April |
Cheapest in | September |
Average price | $552 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Thu 8/27
3:40 pm-10:05 pm
2 stops7h 25m
Lambert-St Louis
Fri 8/28
12:55 pm-10:25 pm
2 stops8h 30m
$325
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Wed 10/7
6:00 am-2:17 pm
2 stops9h 17m
Lambert-St Louis
Sat 10/10
1:25 pm-11:28 pm
2 stops9h 03m
$402
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Tue 9/1
6:00 am-12:02 pm
1 stop7h 02m
Lambert-St Louis
Wed 9/2
8:00 am-2:34 pm
1 stop5h 34m
$423
Quickest round-trip
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Thu 11/5
6:00 am-10:51 am
1 stop5h 51m
Lambert-St Louis
Wed 11/11
6:45 am-11:53 am
1 stop4h 08m
$427
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Thu 11/5
1:40 pm-9:00 pm
2 stops8h 20m
Lambert-St Louis
Wed 11/11
6:20 am-2:50 pm
2 stops7h 30m
$437
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Tue 8/4
6:30 am-11:47 am
1 stop6h 17m
Lambert-St Louis
Mon 8/10
3:39 pm-11:13 pm
1 stop6h 34m
$437
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Thu 7/30
5:35 am-6:30 pm
2 stops13h 55m
Lambert-St Louis
Sun 8/2
5:10 pm-12:10 am
1 stop6h 00m
$448
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Sat 8/1
5:35 am-12:55 pm
2 stops8h 20m
Lambert-St Louis
Sat 8/1
3:45 pm-11:45 pm
2 stops7h 00m
$513
Cheapest one-way
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Wed 10/21
9:20 am-3:00 pm
2 stops6h 40m
$144
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Mon 8/24
7:00 am-5:22 pm
2 stops11h 22m
$158
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PWM-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
What is the cheapest month to book a flight from Portland, Maine to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Portland, Maine to St. Louis (average of $333). Flying from Portland, Maine to St. Louis in April is currently the most expensive (average of $568). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 7, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Portland to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Browse thousands of different options on Cheapflights for your next trip
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Portland and St. Louis flights
Browse other Portland and St. Louis flight options. Last updated on July 7, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on July 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 7, 2026.
Top 3 airlines flying from Portland to St. Louis
Discover the top 3 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$407 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$275 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$348 | Average$549 | FlexibilityNo cancel fee | On-time63% |