$147+ Cheap flights from Portland, ME to St. Louis (PWM - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to St. Louis
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Best
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Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 15m
Thu 11/196:40 am -
1 stop4h 18m
Deal found 10/21![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:25 am -
2 stops9h 45m
Mon 12/146:35 am -
1 stop7h 10m
Deal found 10/22![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops7h 40m
Mon 11/235:00 pm -
1 stop5h 21m
Deal found 10/23![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/207:30 am -
1 stop5h 46m
Deal found 10/21![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:45 pm -
2 stops7h 40m
Mon 12/76:35 am -
1 stop4h 35m
Deal found 10/24![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:25 pm -
2 stops7h 35m
Wed 11/186:20 am -
2 stops7h 25m
Deal found 10/24![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop6h 29m
Tue 12/225:21 pm -
1 stop4h 45m
Deal found 10/20![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:41 pm -
1 stop7h 11m
Tue 11/247:30 am -
1 stop5h 46m
Deal found 10/20![United Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:10 pm -
1 stop4h 50m
Tue 12/222:35 pm -
2 stops8h 20m
Deal found 10/22![Southwest logo]()
$380
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 15m
Thu 11/196:40 am -
1 stop4h 18m
Deal found 10/21![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:50 am -
1 stop5h 58m
Mon 11/231:08 pm -
1 stop7h 43m
Deal found 10/23![United Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/121:00 pm -
2 stops7h 35m
Mon 12/146:20 am -
2 stops7h 25m
Deal found 10/22![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:35 am -
1 stop7h 45m
Sun 1/106:30 am -
1 stop4h 40m
Deal found 10/23![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/207:30 am -
1 stop5h 46m
Deal found 10/21![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/277:30 am -
1 stop5h 46m
Deal found 10/22![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop6h 29m
Tue 12/225:21 pm -
1 stop4h 45m
Deal found 10/20![Delta logo]()
$374
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:20 pm -
1 stop7h 35m
Tue 12/221:40 pm -
2 stops9h 15m
Deal found 10/20![Southwest logo]()
$394
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/79:10 am -
2 stops9h 40m
Sun 1/104:57 pm -
1 stop5h 35m
Deal found 10/25![United Airlines logo]()
$399
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated October 25, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 15m
Thu 11/196:40 am -
1 stop4h 18m
Deal found 10/21![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/207:30 am -
1 stop5h 46m
Deal found 10/21![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:27 am -
1 stop6h 21m
Wed 11/1810:00 am -
1 stop5h 38m
Deal found 10/24![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:25 pm -
2 stops7h 35m
Wed 11/186:20 am -
2 stops7h 25m
Deal found 10/24![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:41 pm -
1 stop7h 11m
Tue 11/247:30 am -
1 stop5h 46m
Deal found 10/20![United Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
2 stops7h 40m
Thu 11/197:30 am -
1 stop5h 46m
Deal found 10/21![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops7h 40m
Mon 11/235:00 pm -
1 stop5h 21m
Deal found 10/23![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:08 pm -
1 stop5h 32m
Mon 11/233:15 pm -
2 stops7h 06m
Deal found 10/22![United Airlines logo]()
$411
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:50 am -
1 stop5h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$147
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:45 am -
1 stop7h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
1 stop8h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$201
This deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/123:41 pm -
1 stop7h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:28 pm -
3 stops47h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$230
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:49 am -
2 stops7h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$234
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:50 am -
2 stops10h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$237
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
2 stops13h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$248
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Delta) |
One-way from | $147 (United Airlines) |
Popular in | April |
Cheapest in | March |
Average price | $429 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/17
2:05 pm-9:42 pm
1 stop8h 37m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Sat 12/12
6:00 am-2:41 pm
2 stops9h 41m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$152
Quickest round-trip
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/17
5:15 am-11:00 am
2 stops6h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$152
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 12/1
5:45 am-12:14 pm
1 stop7h 29m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$192
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Fri 12/25
6:00 am-1:13 pm
1 stop8h 13m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$201
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/24
8:49 am-3:43 pm
2 stops7h 54m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$234
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Fri 12/25
6:00 am-6:18 pm
2 stops13h 18m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$248
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/17
6:00 am-11:15 am
1 stop6h 15m
Lambert-St Louis
Thu 11/19
6:40 am-11:58 am
1 stop4h 18m
$293
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 11/19
5:50 am-10:48 am
1 stop5h 58m
Lambert-St Louis
Mon 11/23
1:08 pm-9:51 pm
1 stop7h 43m
$293
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 12/1
7:00 am-10:59 pm
2 stops16h 59m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$304
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PWM-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
What is the cheapest month to book a flight from Portland, Maine to St. Louis?
Currently, March is the cheapest month in which you can book a flight from Portland, Maine to St. Louis (average of $334). Flying from Portland, Maine to St. Louis in April is currently the most expensive (average of $568). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to St. Louis?
Airfare is below average for this route at the moment.
Portland, Maine to St. Louis flights typically cost between $391 and $578 in November.The cheapest round-trip price found within the last 5 days was $293 on Delta (Nov 17-Nov 19).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 25, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Portland to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
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Portland and St. Louis flights
Browse other Portland and St. Louis flight options. Last updated on October 25, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Top 4 airlines flying from Portland to St. Louis
Discover the top 4 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$280 | Average$526 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$314 | Average$436 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$348 | Average$549 | FlexibilityNo cancel fee | On-time63% |