$134+ Cheap flights from Portland, ME (PWM) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to MissouriExplore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:15 am -
1 stop7h 20m
Thu 12/175:00 am -
1 stop4h 30m
Deal found 10/21![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:23 pm -
1 stop9h 29m
Mon 11/165:50 pm -
1 stop5h 09m
Deal found 10/22![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:05 pm -
1 stop9h 05m
Tue 11/176:00 am -
2 stops9h 10m
Deal found 10/22![Delta logo]()
$272
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:25 am -
2 stops9h 25m
Wed 12/1611:40 am -
2 stops9h 10m
Deal found 10/23![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:27 am -
2 stops10h 59m
Mon 11/163:54 pm -
2 stops7h 25m
Deal found 10/22![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 15m
Thu 11/196:40 am -
1 stop4h 18m
Deal found 10/21![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:25 am -
2 stops9h 45m
Mon 12/146:35 am -
1 stop7h 10m
Deal found 10/22![Southwest logo]()
$298
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:05 pm -
1 stop6h 04m
Sat 11/146:36 am -
1 stop4h 22m
Deal found 10/22![Delta logo]()
$298
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:03 pm -
2 stops8h 52m
Tue 11/176:36 am -
2 stops9h 02m
Deal found 10/22![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops7h 40m
Mon 11/235:00 pm -
1 stop5h 21m
Deal found 10/23![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop6h 09m
Sun 11/226:36 am -
1 stop4h 22m
Deal found 10/21![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:23 pm -
1 stop9h 29m
Thu 11/197:36 am -
1 stop5h 40m
Deal found 10/22![United Airlines logo]()
$325
Best flights from Portland to MissouriDiscover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:23 pm -
1 stop9h 29m
Mon 11/165:50 pm -
1 stop5h 09m
Deal found 10/22![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2412:50 pm -
1 stop5h 25m
Sat 2/276:00 am -
1 stop4h 53m
Deal found 10/20![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/121:00 pm -
2 stops7h 35m
Mon 12/146:20 am -
2 stops7h 25m
Deal found 10/22![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 15m
Thu 11/196:40 am -
1 stop4h 18m
Deal found 10/21![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:50 am -
1 stop5h 58m
Mon 11/231:08 pm -
1 stop7h 43m
Deal found 10/23![United Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:35 am -
1 stop7h 45m
Sun 1/106:30 am -
1 stop4h 40m
Deal found 10/23![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:10 pm -
1 stop8h 15m
Sun 12/206:00 pm -
1 stop4h 55m
Deal found 10/20![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:23 pm -
1 stop9h 29m
Thu 11/197:36 am -
1 stop5h 40m
Deal found 10/22![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops12h 48m
Sun 11/226:36 am -
1 stop4h 22m
Deal found 10/21![Delta logo]()
$326
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/207:30 am -
1 stop5h 46m
Deal found 10/21![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/277:30 am -
1 stop5h 46m
Deal found 10/22![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop6h 29m
Tue 12/225:21 pm -
1 stop4h 45m
Deal found 10/20![Delta logo]()
$374
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:20 pm -
1 stop7h 35m
Tue 12/221:40 pm -
2 stops9h 15m
Deal found 10/20![Southwest logo]()
$394
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2412:45 pm -
1 stop5h 17m
Sat 1/306:30 am -
1 stop4h 37m
Deal found 10/24![Delta logo]()
$388
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:49 am -
2 stops8h 45m
Wed 11/1111:18 am -
2 stops11h 03m
Deal found 10/23![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:45 am -
1 stop17h 57m
Sun 11/87:15 am -
1 stop14h 18m
Deal found 10/23![American Airlines logo]()
$1,258
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/79:10 am -
2 stops9h 40m
Sun 1/104:57 pm -
1 stop5h 35m
Deal found 10/25![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:51 am -
1 stop5h 47m
Wed 12/163:15 pm -
2 stops7h 43m
Deal found 10/20![United Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/69:10 am -
2 stops13h 34m
Sat 1/97:30 am -
1 stop6h 21m
Deal found 10/24![United Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:08 pm -
1 stop6h 50m
Tue 11/108:00 am -
1 stop5h 16m
Deal found 10/21![United Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:08 pm -
1 stop6h 50m
Sun 11/83:00 pm -
1 stop22h 16m
Deal found 10/23![United Airlines logo]()
$1,151
Last-minute flights from Portland to MissouriDiscover last-minute flight deals from Portland to Missouri. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Missouri. Data last updated October 25, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:23 pm -
1 stop9h 29m
Mon 11/165:50 pm -
1 stop5h 09m
Deal found 10/22![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:05 pm -
1 stop9h 05m
Tue 11/176:00 am -
2 stops9h 10m
Deal found 10/22![Delta logo]()
$272
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:27 am -
2 stops10h 59m
Mon 11/163:54 pm -
2 stops7h 25m
Deal found 10/22![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:05 pm -
1 stop6h 04m
Sat 11/146:36 am -
1 stop4h 22m
Deal found 10/22![Delta logo]()
$298
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:15 am -
1 stop7h 20m
Sun 11/155:00 am -
1 stop4h 30m
Deal found 10/22![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:03 pm -
2 stops8h 52m
Mon 11/161:20 pm -
2 stops9h 59m
Deal found 10/22![Delta logo]()
$313
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:03 pm -
2 stops8h 52m
Sat 11/146:36 am -
1 stop4h 22m
Deal found 10/22![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:23 pm -
1 stop9h 29m
Thu 11/197:36 am -
1 stop5h 40m
Deal found 10/22![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 15m
Thu 11/196:40 am -
1 stop4h 18m
Deal found 10/21![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:50 am -
1 stop5h 58m
Fri 11/207:30 am -
1 stop5h 46m
Deal found 10/21![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops7h 40m
Mon 11/235:00 pm -
1 stop5h 21m
Deal found 10/23![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop6h 09m
Sun 11/226:36 am -
1 stop4h 22m
Deal found 10/21![Delta logo]()
$321
One-way flights from Portland to MissouriSearch for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:47 pm -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$134
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:53 pm -
2 stops8h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$139
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:50 am -
1 stop5h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$147
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:25 pm -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$153
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:45 am -
1 stop7h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
1 stop8h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$201
This deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/123:41 pm -
1 stop7h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/189:48 am -
1 stop32h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$206
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
2 stops11h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:28 pm -
3 stops47h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$230
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:49 am -
2 stops7h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$234
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:50 am -
2 stops10h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$237
Find flight deals from Portland to Missouri
Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $262 (Southwest) |
One-way from | $134 (United Airlines) |
Popular in | April |
Cheapest in | March |
Average price | $429 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Wed 12/9
4:47 pm-11:07 pm
1 stop7h 20m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$134
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Wed 12/9
4:53 pm-11:56 pm
2 stops8h 03m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$139
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/17
2:05 pm-9:42 pm
1 stop8h 37m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Quickest round-trip
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/17
5:15 am-11:00 am
2 stops6h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$152
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Sat 12/12
6:00 am-2:41 pm
2 stops9h 41m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$152
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Sat 12/19
5:25 pm-12:20 am
1 stop7h 55m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$153
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 12/1
5:45 am-12:14 pm
1 stop7h 29m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$192
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Fri 12/25
6:00 am-1:13 pm
1 stop8h 13m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$201
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/24
8:49 am-3:43 pm
2 stops7h 54m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$234
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Sun 12/20
1:10 pm-11:50 pm
1 stop11h 40m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$244
Showing 1-10 of 39 resultsSorted by cheapest first
Best time to book a flight from Portland to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
PWM-MCI
PWM-STL
PWM-SGF
PWM-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Missouri
PWM-USMO
PWM-MCI
PWM-STL
PWM-SGF
PWM-COU
What is the cheapest month to book a flight from Portland, Maine to Missouri?
Currently, September is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $426). Flying from Portland, Maine to Missouri in December is currently the most expensive (average of $661). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to Missouri?
Airfare is below average for this route at the moment.
Portland, Maine to Missouri flights typically cost between $391 and $578 in November.The cheapest round-trip price found within the last 5 days was $293 on Delta (Nov 17-Nov 19).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 25, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Entertainment
7.4
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Overall
7.9
Entertainment
7.4
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Overall
7.9
Entertainment
7.4
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Overall
7.9
Entertainment
7.4
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Overall
7.9
Entertainment
7.4
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
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Alternative routes for Portland to Missouri
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Complete your trip
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Find flights from Portland to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Missouri flights
Browse other Portland and Missouri flight options. Last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Missouri flights
Consider these flights traveling from Portland to Missouri.
Top 4 airlines flying from Portland to Missouri
Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$471 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$280 | Average$462 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$464 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$332 | Average$529 | FlexibilityNo cancel fee | On-time63% |