$129+ Cheap flights from Portland, ME (PWM) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Sep 5 — Sep 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to MissouriExplore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:09 pm -
2 stops21h 01m
Fri 10/25:19 pm -
1 stop14h 49m
Deal found 8/3![Multiple Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:41 pm -
1 stop5h 36m
Sun 9/275:18 pm -
1 stop5h 29m
Deal found 8/5![American Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:04 pm -
1 stop8h 14m
Sat 11/141:38 pm -
2 stops8h 19m
Deal found 8/3![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
1 stop6h 16m
Mon 10/194:30 pm -
1 stop5h 01m
Deal found 8/1![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:38 pm -
2 stops8h 06m
Mon 9/77:30 am -
1 stop6h 04m
Deal found 8/2![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 am -
1 stop5h 12m
Sun 9/65:40 pm -
1 stop5h 07m
Deal found 8/4![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:46 pm -
1 stop5h 48m
Thu 9/105:18 pm -
1 stop5h 29m
Deal found 8/2![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:15 am -
2 stops7h 47m
Sun 9/68:30 am -
1 stop4h 59m
Deal found 8/4![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop6h 16m
Sat 10/174:57 pm -
1 stop5h 44m
Deal found 8/2![American Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:20 am -
1 stop5h 45m
Mon 11/95:00 am -
1 stop4h 30m
Deal found 8/4![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:03 pm -
1 stop7h 16m
Mon 8/243:03 pm -
1 stop5h 20m
Deal found 8/3![United Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:09 pm -
2 stops21h 01m
Fri 10/98:34 pm -
1 stop11h 34m
Deal found 8/3![Multiple Airlines logo]()
$376
Best flights from Portland to MissouriDiscover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
Discover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:28 pm -
1 stop5h 41m
Sat 10/172:36 pm -
1 stop5h 24m
Deal found 8/6![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:40 pm -
2 stops7h 30m
Mon 9/142:20 pm -
1 stop6h 15m
Deal found 8/5![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:03 pm -
1 stop7h 16m
Mon 8/243:03 pm -
1 stop5h 20m
Deal found 8/3![United Airlines logo]()
$374
This KAYAK deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:08 am -
1 stop8h 12m
Wed 9/26:00 am -
1 stop5h 40m
Deal found 8/5![American Airlines logo]()
$441
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:09 pm -
1 stop8h 08m
Mon 11/96:00 am -
1 stop6h 03m
Deal found 8/5![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:45 am -
1 stop5h 20m
Mon 9/212:45 pm -
2 stops6h 45m
Deal found 8/3![Southwest logo]()
$390
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:58 am -
1 stop5h 15m
Fri 10/21:29 pm -
1 stop7h 17m
Deal found 8/4![United Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:28 pm -
1 stop5h 41m
Mon 11/96:00 am -
1 stop6h 03m
Deal found 8/5![Delta logo]()
$376
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:55 am -
1 stop5h 15m
Fri 10/25:40 pm -
1 stop5h 15m
Deal found 8/4![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:38 pm -
1 stop5h 54m
Fri 10/95:08 pm -
1 stop5h 32m
Deal found 8/1![American Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:03 pm -
1 stop5h 41m
Sat 9/512:10 pm -
1 stop6h 08m
Deal found 8/5![United Airlines logo]()
$421
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:40 am -
1 stop7h 10m
Mon 9/212:35 pm -
2 stops6h 55m
Deal found 8/3![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop8h 26m
Fri 11/276:40 am -
1 stop4h 28m
Deal found 8/1![Delta logo]()
$424
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:08 pm -
1 stop5h 32m
Fri 11/273:15 pm -
2 stops7h 06m
Deal found 8/1![United Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
1 stop7h 06m
Sat 10/101:39 pm -
2 stops8h 05m
Deal found 8/5![American Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/99:45 am -
1 stop5h 34m
Wed 1/138:00 am -
1 stop4h 52m
Deal found 8/4![United Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/225:35 am -
2 stops9h 45m
Sun 1/243:55 pm -
1 stop4h 45m
Deal found 8/2![Southwest logo]()
$435
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/274:48 pm -
1 stop5h 35m
Sat 1/303:03 pm -
1 stop5h 24m
Deal found 8/5![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:08 pm -
1 stop5h 32m
Wed 10/281:00 pm -
1 stop5h 02m
Deal found 8/5![United Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:50 am -
2 stops9h 43m
Sun 11/157:30 am -
1 stop5h 46m
Deal found 8/2![United Airlines logo]()
$486
Last-minute flights from Portland to MissouriDiscover last-minute flight deals from Portland to Missouri. Data last updated August 6, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Missouri. Data last updated August 6, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:03 pm -
1 stop7h 16m
Mon 8/243:03 pm -
1 stop5h 20m
Deal found 8/3![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:06 pm -
1 stop8h 04m
Sat 8/227:00 am -
1 stop6h 24m
Deal found 8/3![American Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:38 pm -
2 stops8h 06m
Mon 9/77:30 am -
1 stop6h 04m
Deal found 8/2![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 am -
1 stop5h 12m
Sun 9/65:40 pm -
1 stop5h 07m
Deal found 8/4![American Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:15 am -
2 stops7h 47m
Sun 9/68:30 am -
1 stop4h 59m
Deal found 8/4![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:55 am -
2 stops10h 15m
Sun 9/66:45 am -
2 stops7h 45m
Deal found 8/4![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:46 pm -
1 stop5h 48m
Thu 9/105:18 pm -
1 stop5h 29m
Deal found 8/2![American Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
1 stop5h 15m
Mon 9/215:13 pm -
1 stop5h 32m
Deal found 8/3![American Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:15 am -
2 stops7h 42m
Mon 9/213:32 pm -
1 stop4h 51m
Deal found 8/4![United Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:05 pm -
1 stop5h 49m
Mon 9/283:59 pm -
1 stop6h 48m
Deal found 8/2![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:41 pm -
1 stop5h 36m
Sun 9/275:18 pm -
1 stop5h 29m
Deal found 8/5![American Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:09 pm -
2 stops21h 01m
Fri 10/25:19 pm -
1 stop14h 49m
Deal found 8/3![Multiple Airlines logo]()
$337
One-way flights from Portland to MissouriSearch for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
Search for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:00 am -
3 stops58h 22m
Deal found 8/2![Multiple Airlines logo]()
$129
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
1 stop7h 57m
Deal found 8/2![Delta logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:09 pm -
2 stops21h 01m
Deal found 8/2![Multiple Airlines logo]()
$171
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop8h 21m
Deal found 8/4![Delta logo]()
$175
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am -
2 stops9h 25m
Deal found 8/5![Southwest logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:09 pm -
2 stops21h 01m
Deal found 8/4![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:09 pm -
2 stops24h 15m
Deal found 8/2![Multiple Airlines logo]()
$191
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:59 pm -
1 stop7h 07m
Deal found 8/3![Delta logo]()
$193
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
2 stops9h 28m
Deal found 8/2![United Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:01 pm -
3 stops42h 40m
Deal found 8/1![Multiple Airlines logo]()
$198
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:28 pm -
1 stop5h 41m
Deal found 8/4![Delta logo]()
$202
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:55 am -
2 stops10h 15m
Deal found 8/1![Southwest logo]()
$204
Find flight deals from Portland to Missouri
Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated August 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (Kiwi.com) |
One-way from | $129 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $442 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Tue 10/13
5:28 pm-10:09 pm
1 stop5h 41m
Kansas City
Sat 10/17
2:36 pm-9:00 pm
1 stop5h 24m
$349
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Sat 11/7
2:09 pm-9:17 pm
1 stop8h 08m
Kansas City
Mon 11/9
6:00 am-1:03 pm
1 stop6h 03m
$349
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Fri 9/11
3:40 pm-10:10 pm
2 stops7h 30m
Lambert-St Louis
Mon 9/14
2:20 pm-9:35 pm
1 stop6h 15m
$367
PortlandSpringfield
PWM Portland - SGF Springfield-Branson
PWMSGF
Portland
Wed 8/19
5:03 pm-11:19 pm
1 stop7h 16m
Springfield-Branson
Mon 8/24
3:03 pm-9:23 pm
1 stop5h 20m
$374
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Fri 11/6
5:28 pm-10:09 pm
1 stop5h 41m
Kansas City
Mon 11/9
6:00 am-1:03 pm
1 stop6h 03m
$376
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Wed 9/16
5:45 am-10:05 am
1 stop5h 20m
Lambert-St Louis
Mon 9/21
2:45 pm-10:30 pm
2 stops6h 45m
$390
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 9/29
7:58 am-12:13 pm
1 stop5h 15m
Lambert-St Louis
Fri 10/2
1:29 pm-9:46 pm
1 stop7h 17m
$398
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Mon 9/28
5:55 am-10:10 am
1 stop5h 15m
Lambert-St Louis
Fri 10/2
5:40 pm-11:55 pm
1 stop5h 15m
$398
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Sat 9/19
5:40 am-11:50 am
1 stop7h 10m
Kansas City
Mon 9/21
2:35 pm-10:30 pm
2 stops6h 55m
$400
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Thu 9/3
5:03 pm-9:44 pm
1 stop5h 41m
Kansas City
Sat 9/5
12:10 pm-7:18 pm
1 stop6h 08m
$421
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Portland to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
PWM-STL
PWM-MCI
PWM-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Missouri
PWM-USMO
PWM-STL
PWM-MCI
PWM-SGF
What is the cheapest month to book a flight from Portland, Maine to Missouri?
Currently, September is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $411). Flying from Portland, Maine to Missouri in December is currently the most expensive (average of $613). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to Missouri?
Airfare is below average for this route at the moment.
Portland, Maine to Missouri flights typically cost between $381 and $590 in September.The cheapest round-trip price found within the last 5 days was $337 on Multiple Airlines (Sep 29-Oct 2).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 6, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Portland to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Missouri by cabin class
Find flights from Portland to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Missouri flights
Browse other Portland and Missouri flight options. Last updated on August 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Missouri flights
Consider these flights traveling from Portland to Missouri.
Top 4 airlines flying from Portland to Missouri
Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$262 | Average$437 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$332 | Average$536 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$337 | Average$462 | FlexibilityNo cancel fee | On-time69% |