$157+ Cheap flights from Portland, ME (PWM) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Sep 18 — Sep 251
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to MissouriExplore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 16m
Wed 10/214:30 pm -
1 stop5h 01m
Deal found 8/14![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
1 stop5h 25m
Tue 10/276:20 am -
2 stops8h 10m
Deal found 8/15![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:28 pm -
1 stop5h 41m
Mon 11/93:54 pm -
1 stop6h 39m
Deal found 8/18![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 pm -
1 stop7h 55m
Tue 10/276:20 am -
2 stops8h 10m
Deal found 8/15![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop7h 13m
Sat 10/178:00 am -
1 stop5h 38m
Deal found 8/16![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
1 stop5h 42m
Sat 9/1912:01 pm -
1 stop7h 59m
Deal found 8/19![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:40 am -
2 stops8h 45m
Tue 9/83:45 pm -
1 stop5h 25m
Deal found 8/17![Southwest logo]()
$344
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:20 am -
1 stop7h 14m
Sat 10/176:00 am -
1 stop6h 03m
Deal found 8/18![Delta logo]()
$352
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:20 am -
1 stop5h 45m
Sat 10/317:40 am -
2 stops8h 55m
Deal found 8/15![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:53 pm -
1 stop5h 45m
Mon 9/2112:59 pm -
1 stop7h 24m
Deal found 8/17![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:27 pm -
1 stop5h 25m
Mon 10/199:17 am -
1 stop6h 40m
Deal found 8/18![American Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
2 stops8h 50m
Mon 10/264:10 pm -
2 stops6h 45m
Deal found 8/15![Southwest logo]()
$368
Best flights from Portland to MissouriDiscover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
Discover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:01 am -
1 stop5h 52m
Sun 10/185:27 pm -
1 stop5h 08m
Deal found 8/18![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 am -
2 stops7h 40m
Sat 10/313:15 pm -
1 stop5h 36m
Deal found 8/16![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 pm -
2 stops8h 05m
Sat 10/317:00 am -
2 stops9h 35m
Deal found 8/16![Southwest logo]()
$372
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:32 am -
2 stops8h 35m
Sat 9/193:41 pm -
1 stop7h 06m
Deal found 8/16![American Airlines logo]()
$460
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
1 stop6h 09m
Mon 12/143:15 pm -
2 stops6h 42m
Deal found 8/18![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:53 pm -
1 stop5h 45m
Mon 9/2112:59 pm -
1 stop7h 24m
Deal found 8/17![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:25 am -
2 stops10h 15m
Tue 1/55:25 am -
2 stops8h 20m
Deal found 8/15![Southwest logo]()
$405
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop6h 15m
Thu 10/12:26 pm -
1 stop8h 02m
Deal found 8/19![Delta logo]()
$426
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop5h 48m
Sat 9/123:03 pm -
2 stops7h 56m
Deal found 8/15![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:25 am -
2 stops9h 45m
Mon 12/146:20 am -
2 stops7h 25m
Deal found 8/18![Southwest logo]()
$421
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop5h 12m
Sun 9/1312:59 pm -
1 stop7h 24m
Deal found 8/14![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:05 pm -
1 stop8h 10m
Wed 9/2311:55 am -
2 stops8h 20m
Deal found 8/17![Southwest logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop7h 13m
Sun 10/188:00 am -
1 stop5h 38m
Deal found 8/18![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:45 am -
1 stop5h 20m
Thu 10/15:50 pm -
1 stop5h 05m
Deal found 8/14![Southwest logo]()
$454
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:08 pm -
1 stop5h 43m
Mon 11/911:33 am -
2 stops10h 48m
Deal found 8/19![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/29:45 am -
1 stop8h 11m
Wed 2/35:00 am -
1 stop7h 52m
Deal found 8/18![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:08 pm -
1 stop5h 32m
Wed 10/281:00 pm -
1 stop5h 02m
Deal found 8/16![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/66:00 am -
2 stops9h 19m
Wed 2/108:00 am -
1 stop4h 52m
Deal found 8/14![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:45 am -
2 stops9h 57m
Sun 9/65:39 pm -
1 stop5h 20m
Deal found 8/15![United Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:08 pm -
1 stop5h 43m
Mon 11/911:33 am -
2 stops10h 48m
Deal found 8/15![United Airlines logo]()
$453
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:03 am -
2 stops7h 15m
Thu 10/16:29 am -
1 stop6h 22m
Deal found 8/19![United Airlines logo]()
$453
Last-minute flights from Portland to MissouriDiscover last-minute flight deals from Portland to Missouri. Data last updated August 19, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Missouri. Data last updated August 19, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:35 am -
1 stop7h 53m
Sat 9/123:03 pm -
1 stop5h 20m
Deal found 8/15![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:01 am -
1 stop8h 03m
Sun 9/66:20 am -
1 stop4h 42m
Deal found 8/17![Delta logo]()
$391
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:53 pm -
1 stop5h 45m
Tue 9/812:28 pm -
1 stop5h 01m
Deal found 8/17![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:40 am -
2 stops8h 45m
Tue 9/83:45 pm -
1 stop5h 25m
Deal found 8/17![Southwest logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:30 am -
1 stop5h 41m
Wed 9/165:37 am -
1 stop6h 28m
Deal found 8/16![American Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop5h 12m
Sun 9/1312:59 pm -
1 stop7h 24m
Deal found 8/14![United Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:53 pm -
1 stop5h 45m
Mon 9/2112:59 pm -
1 stop7h 24m
Deal found 8/17![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
1 stop5h 42m
Sat 9/1912:01 pm -
1 stop7h 59m
Deal found 8/19![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 am -
1 stop5h 59m
Thu 9/245:13 pm -
1 stop5h 32m
Deal found 8/18![American Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:15 am -
2 stops7h 42m
Sun 9/273:11 pm -
1 stop5h 35m
Deal found 8/17![United Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:38 pm -
1 stop7h 45m
Sun 9/272:14 pm -
1 stop8h 33m
Deal found 8/19![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:38 pm -
1 stop7h 45m
Mon 9/285:13 am -
1 stop6h 52m
Deal found 8/15![American Airlines logo]()
$331
One-way flights from Portland to MissouriSearch for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
Search for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:53 pm -
1 stop6h 06m
Deal found 8/14![United Airlines logo]()
$157
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop6h 22m
Deal found 8/16![United Airlines logo]()
$170
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:28 pm -
1 stop5h 41m
Deal found 8/14![Delta logo]()
$175
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:41 am -
1 stop5h 38m
Deal found 8/14![American Airlines logo]()
$191
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:25 am -
1 stop7h 38m
Deal found 8/17![American Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:08 am -
1 stop5h 22m
Deal found 8/16![American Airlines logo]()
$196
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:38 pm -
2 stops8h 06m
Deal found 8/16![United Airlines logo]()
$201
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/511:17 am -
2 stops11h 32m
Deal found 8/14![United Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:00 am -
3 stops27h 41m
Deal found 8/16![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:00 am -
2 stops37h 37m
Deal found 8/14![Multiple Airlines logo]()
$217
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:08 pm -
1 stop5h 56m
Deal found 8/14![United Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:09 pm -
3 stops51h 28m
Deal found 8/14![Multiple Airlines logo]()
$230
Find flight deals from Portland to Missouri
Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated August 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $313 (American Airlines) |
One-way from | $157 (United Airlines) |
Popular in | December |
Cheapest in | January |
Average price | $434 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSpringfield
PWM Portland - SGF Springfield-Branson
PWMSGF
Portland
Sun 10/11
6:01 am-10:53 am
1 stop5h 52m
Springfield-Branson
Sun 10/18
5:27 pm-11:35 pm
1 stop5h 08m
$339
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 10/29
5:30 am-12:10 pm
2 stops7h 40m
Lambert-St Louis
Sat 10/31
3:15 pm-9:51 pm
1 stop5h 36m
$344
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Sat 12/12
6:00 am-11:09 am
1 stop6h 09m
Lambert-St Louis
Mon 12/14
3:15 pm-10:57 pm
2 stops6h 42m
$344
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Mon 9/14
6:53 pm-11:38 pm
1 stop5h 45m
Lambert-St Louis
Mon 9/21
12:59 pm-9:23 pm
1 stop7h 24m
$359
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 10/29
5:30 pm-12:35 am
2 stops8h 05m
Lambert-St Louis
Sat 10/31
7:00 am-5:35 pm
2 stops9h 35m
$372
PortlandSpringfield
PWM Portland - SGF Springfield-Branson
PWMSGF
Portland
Tue 9/1
6:00 am-10:48 am
1 stop5h 48m
Springfield-Branson
Sat 9/12
3:03 pm-11:59 pm
2 stops7h 56m
$379
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 9/10
6:00 am-10:12 am
1 stop5h 12m
Lambert-St Louis
Sun 9/13
12:59 pm-9:23 pm
1 stop7h 24m
$388
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 10/15
6:00 am-12:13 pm
1 stop7h 13m
Lambert-St Louis
Sun 10/18
8:00 am-2:38 pm
1 stop5h 38m
$388
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Wed 12/30
5:25 am-2:40 pm
2 stops10h 15m
Kansas City
Tue 1/5
5:25 am-2:45 pm
2 stops8h 20m
$405
PortlandKansas City
PWM Portland - MCI Kansas City
PWMMCI
Portland
Sat 11/7
5:08 pm-9:51 pm
1 stop5h 43m
Kansas City
Mon 11/9
11:33 am-11:21 pm
2 stops10h 48m
$408
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Portland to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
PWM-MCI
PWM-STL
PWM-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Missouri
PWM-USMO
PWM-MCI
PWM-STL
PWM-SGF
What is the cheapest month to book a flight from Portland, Maine to Missouri?
Currently, September is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $415). Flying from Portland, Maine to Missouri in December is currently the most expensive (average of $613). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to Missouri?
Airfare is below average for this route at the moment.
Portland, Maine to Missouri flights typically cost between $381 and $662 in October.The cheapest round-trip price found within the last 5 days was $339 on United Airlines (Oct 7-Oct 17).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 19, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Missouri by cabin class
Find flights from Portland to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Missouri flights
Browse other Portland and Missouri flight options. Last updated on August 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Missouri flights
Consider these flights traveling from Portland to Missouri.
Top 4 airlines flying from Portland to Missouri
Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$431 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$314 | Average$476 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$461 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$348 | Average$536 | FlexibilityNo cancel fee | On-time63% |