Cheap flights from St. Louis to Knoxville (STL - TYS) from $129

This is the cheapest one-way flight price, found on 5/31. Prices may vary by date and flight preferences.
STL — TYS
Jun 6 — Jun 131

The best prices from Lambert-St Louis to Knoxville McGhee Tyson are usually found in February or April, booked 60 days in advance, depart on a Tuesday or Saturday and return on a Monday

How to find the cheapest flight from St. Louis (STL) to Knoxville (TYS)

All the information you need to plan the best STL to TYS flight in 2023: compare St. Louis to Knoxville flight prices with the expected peak season, weather and rainfall in Knoxville.

Popular in

October

Cheapest in

February

Round-trip from

$306

One-way from

$160
High demand for flights, 41% potential price rise
Best time to find cheap flights, 23% potential price drop
From Lambert-St Louis to Knoxville McGhee Tyson
One-way flight from Lambert-St Louis to Knoxville McGhee Tyson

STL - TYS

Price

$306 - $520

TYS

Temperature

39.2 - 78.8 °F

TYS

Rainfall

2.7 - 4.8 inches

Cheap flights from St. Louis to Knoxville in June, July 2023

The best prices found for STL to TYS flights for June, July
The lowest fares we've come across on flights traveling from St. Louis to Knoxville in June and July 2023. Check back soon for alternative fares.

St. Louis to Knoxville 2023 flight deals

Cheap flights to Knoxville from St. Louis found for this year
The lowest fares we've come across on flights traveling from St. Louis to Knoxville in June and July 2023. Check back soon for alternative fares.

Cheap American Airlines flights from St. Louis to Knoxville

Take a peek at the cheapest American Airlines flights we've detected traveling from St. Louis to Knoxville. Come back soon if you're not finding the exact deal you're looking for.

Cheap Delta flights from St. Louis to Knoxville

Have a look at some of the cheapest available Delta flights departing from St. Louis and landing in Knoxville. Deals are refreshing constantly so come back soon for more options.

Last minute flights from St. Louis to Knoxville

Late deals on return flights to Knoxville from St. Louis, departing today and this week
Check out these flights departing soon from St. Louis to Knoxville. Users should examine the flight details to ensure there are no surprises.

One-way flights to Knoxville from St. Louis

The cheapest one-way flights from St. Louis to Knoxville
Take a look at some of the best available options we've come across on one-way flights from St. Louis to Knoxville. Those seeking round-trip flights from St. Louis to Knoxville should utilize the search form at the the top of the page.

Find flights from St. Louis to Knoxville within your budget

Use the slider to find flights from St. Louis to Knoxville that fit your budget.

Fly from

Any airport

Fly to

Any airport

Budget

$270 - $419

Route

Depart

Return

Price

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Sat 9/2

1 stop15h 02m

Knoxville McGhee Tyson

Tue 9/5

3 stops48h 45m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Wed 8/16

1 stop15h 32m

Knoxville McGhee Tyson

Fri 8/18

2 stops27h 54m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Sat 9/2

1 stop5h 28m

Knoxville McGhee Tyson

Tue 9/5

1 stop3h 26m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Sat 9/2

1 stop15h 02m

Knoxville McGhee Tyson

Tue 9/5

2 stops26h 43m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Tue 7/11

1 stop24h 41m

Knoxville McGhee Tyson

Tue 7/18

2 stops21h 46m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Sun 7/2

1 stop4h 07m

Knoxville McGhee Tyson

Wed 7/5

1 stop4h 19m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Sat 8/26

2 stops6h 42m

Knoxville McGhee Tyson

Tue 8/29

1 stop4h 32m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Sun 7/2

1 stop4h 07m

Knoxville McGhee Tyson

Wed 7/5

2 stops9h 22m

Lambert-St LouisKnoxville McGhee Tyson

STL - TYS

STLTYS

Lambert-St Louis

Thu 7/20

1 stop5h 17m

Knoxville McGhee Tyson

Sun 7/23

1 stop6h 24m

Flights are sorted by cheapest first

Deals found on 5/31

Reviews of Airlines Servicing Knoxville

To help decide which airline to fly from St. Louis to Knoxville, see what other customers have to say about American Airlines and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
2,369 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.8

Reviews

1 / 10

Flights were on time with no delays, luggage arrived with the flight. I know the flights were short, but the only drinks offered were water, tea and coffee. It would’ve been nice to have the option to choose a soda, especially since I was in comfort class. The snacks were very small.

Delta
8.0
Very good
2,369 reviews
Delta
8.0
Very good
2,369 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.8

Reviews

1 / 10

Flights were on time with no delays, luggage arrived with the flight. I know the flights were short, but the only drinks offered were water, tea and coffee. It would’ve been nice to have the option to choose a soda, especially since I was in comfort class. The snacks were very small.

American Airlines
7.3
Good
2,149 reviews
Delta
8.0
Very good
2,369 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.8

Reviews

1 / 10

Flights were on time with no delays, luggage arrived with the flight. I know the flights were short, but the only drinks offered were water, tea and coffee. It would’ve been nice to have the option to choose a soda, especially since I was in comfort class. The snacks were very small.

Related info for your journey

Useful info, stats and facts about St. Louis to Knoxville flights.

Top 2 airlines flying from St. Louis to Knoxville

The chart below displays the airlines Cheapflights users traveling from St. Louis to Knoxville choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.
AirlineCheapestAverageFlexibilityOn-timeCOVID-19 safety
American AirlinesCheapest$331Average$465FlexibilityNo cancel feeOn-time71%COVID-19 safety
Search American Airlines flights
DeltaCheapest$357Average$466FlexibilityNo cancel feeOn-timeN/ACOVID-19 safety
Search Delta flights
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