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$87+ Cheap flights from Knoxville to St. Louis (TYS - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — STL
Jul 31 — Aug 71
From?
To?
Wed 7/31
Wed 8/7
1 adult, Economy
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Cheap flight deals from Knoxville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2024.

Popular in

May

Cheapest in

April

Round-trip from

$238
(Delta)

One-way from

$87
(mytrip.com)
High demand for flights, 26% potential price rise
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Best time to find cheap flights, 16% potential price drop
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From Knoxville McGhee Tyson to Lambert-St Louis
Search Deals
One-way flight from Knoxville McGhee Tyson to Lambert-St Louis
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What is the cheapest day to fly round-trip from Knoxville to St. Louis?

Sunday flights are found to be more expensive to fly from Knoxville to St. Louis. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

What is the cheapest month to fly from Knoxville to St. Louis?

The best pricing can be found in the month of April. Prices to St. Louis from Knoxville average $301. You can even find prices in April for less than $301, as users have found deals to St. Louis from as low as $214. The month of May appears to be one of the more expensive times to travel to St. Louis from Knoxville. Flying in the targeted month can save you up to 35%.

What is the cheapest time of day to fly from TYS to STL?

A simple way to save on the total cost of your ticket is to fly from Knoxville to St. Louis at noon. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the morning.

Cheap Knoxville to St. Louis flights in July & August 2024

Find cheap flight options from Knoxville to St. Louis specifically for the months of July and August 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,752,877 searches. Prices were last updated on July 26, 2024.
These are some of the most attractive deals on flights from Knoxville to St. Louis in 2024. Check back in a little while for more flight options.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/157:56 pmTYS - STL
1 stop4h 44mDelta
Thu 8/227:06 pmSTL - TYS
1 stop3h 45mDelta
Deal found 7/25$238
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/85:25 amTYS - STL
1 stop4h 24mDelta
Sun 8/116:00 amSTL - TYS
1 stop4h 12mDelta
Deal found 7/25$248
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/188:25 pmTYS - STL
3 stops35h 57mMultiple Airlines
Sun 8/255:18 pmSTL - TYS
1 stop15h 47mMultiple Airlines
Deal found 7/25$294
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/257:49 pmTYS - STL
1 stop4h 40mAmerican Airlines
Sun 7/285:17 amSTL - TYS
1 stop4h 15mAmerican Airlines
Deal found 7/25$298
This mytrip.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2310:55 amTYS - STL
2 stops21h 27mMultiple Airlines
Fri 8/308:12 amSTL - TYS
1 stop13h 34mMultiple Airlines
Deal found 7/24$303
This mytrip.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2310:55 amTYS - STL
3 stops21h 27mMultiple Airlines
Fri 8/308:12 amSTL - TYS
1 stop13h 34mMultiple Airlines
Deal found 7/24$315
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1811:00 amTYS - STL
2 stops26h 58mMultiple Airlines
Sun 8/255:18 pmSTL - TYS
1 stop15h 47mMultiple Airlines
Deal found 7/25$323
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1912:55 pmTYS - STL
2 stops19h 27mMultiple Airlines
Wed 8/211:48 pmSTL - TYS
3 stops28h 47mMultiple Airlines
Deal found 7/25$325
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/188:25 pmTYS - STL
3 stops35h 57mMultiple Airlines
Sun 8/258:12 amSTL - TYS
2 stops24h 53mMultiple Airlines
Deal found 7/25$342

Knoxville to St. Louis 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and St. Louis in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,752,877 searches. Data last updated July 26, 2024.
These are some of the most attractive deals on flights from Knoxville to St. Louis in 2024. Check back in a little while for more flight options.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/157:56 pmTYS - STL
1 stop4h 44mDelta
Thu 8/227:06 pmSTL - TYS
1 stop3h 45mDelta
Deal found 7/25$238
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/194:59 pmTYS - STL
1 stop16h 03mMultiple Airlines
Sun 9/2212:15 pmSTL - TYS
2 stops28h 25mMultiple Airlines
Deal found 7/25$241
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/85:25 amTYS - STL
1 stop4h 24mDelta
Sun 8/116:00 amSTL - TYS
1 stop4h 12mDelta
Deal found 7/25$248
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/194:59 pmTYS - STL
1 stop16h 03mMultiple Airlines
Sun 9/228:57 amSTL - TYS
3 stops33h 10mMultiple Airlines
Deal found 7/25$284
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/188:25 pmTYS - STL
3 stops35h 57mMultiple Airlines
Sun 8/255:18 pmSTL - TYS
1 stop15h 47mMultiple Airlines
Deal found 7/25$294
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/257:49 pmTYS - STL
1 stop4h 40mAmerican Airlines
Sun 7/285:17 amSTL - TYS
1 stop4h 15mAmerican Airlines
Deal found 7/25$298
This mytrip.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2310:55 amTYS - STL
2 stops21h 27mMultiple Airlines
Fri 8/308:12 amSTL - TYS
1 stop13h 34mMultiple Airlines
Deal found 7/24$303
This mytrip.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2310:55 amTYS - STL
3 stops21h 27mMultiple Airlines
Fri 8/308:12 amSTL - TYS
1 stop13h 34mMultiple Airlines
Deal found 7/24$315
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1811:00 amTYS - STL
2 stops26h 58mMultiple Airlines
Sun 8/255:18 pmSTL - TYS
1 stop15h 47mMultiple Airlines
Deal found 7/25$323

One-way flights to St. Louis from Knoxville

Search for one-way flight options from Knoxville to St. Louis. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,752,877 searches. Data last updated July 26, 2024.
If you're seeking multiple options on one-way flights from Knoxville to St. Louis, be sure to check out these deals, which are updated often. For those needing a return trip from Knoxville, there is a search form available above.
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/910:36 pmTYS - STL
1 stop11h 49mFrontier
Deal found 7/25$87
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3110:03 pmTYS - STL
1 stop21h 45mFrontier
Deal found 7/25$127
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/94:49 pmTYS - STL
2 stops18h 45mMultiple Airlines
Deal found 7/25$225
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/316:00 pmTYS - STL
3 stops44h 30mMultiple Airlines
Deal found 7/25$230
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3112:44 pmTYS - STL
2 stops6h 36mAmerican Airlines
Deal found 7/25$237
This mytrip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/96:30 amTYS - STL
3 stops33h 20mMultiple Airlines
Deal found 7/25$247

Find flights from Knoxville to St. Louis within your budget

Customize your flight search to find flights from Knoxville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,752,877 searches. Data last updated July 26, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$238 - $418

Route

Depart

Return

Price

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 8/15

1 stop4h 44m

Lambert-St Louis

Thu 8/22

1 stop3h 45m

$238

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 9/19

1 stop16h 03m

Lambert-St Louis

Sun 9/22

2 stops28h 25m

$241

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 8/8

1 stop4h 24m

Lambert-St Louis

Sun 8/11

1 stop4h 12m

$248

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 9/19

1 stop16h 03m

Lambert-St Louis

Sun 9/22

3 stops33h 10m

$284

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Sun 8/18

3 stops35h 57m

Lambert-St Louis

Sun 8/25

1 stop15h 47m

$294

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Fri 8/23

2 stops21h 27m

Lambert-St Louis

Fri 8/30

1 stop13h 34m

$303

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Fri 8/23

3 stops21h 27m

Lambert-St Louis

Fri 8/30

1 stop13h 34m

$315

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 9/5

2 stops15h 47m

Lambert-St Louis

Sun 9/8

1 stop4h 31m

$363

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Mon 8/19

1 stop5h 40m

Lambert-St Louis

Wed 8/21

1 stop5h 44m

$418

Flights are sorted by cheapest first

Deals found on 7/25

What is the cheapest day to fly from Knoxville to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to St. Louis. Price data was last updated on July 21, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Knoxville to St. Louis flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Best time to book a flight from Knoxville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Temperature and rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature and rainfall totals by month.

STL

Temperature

32 - 80.6 °F

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 26, 2024.
Peruse reviews from past customers who have flown with Delta and United Airlines from Knoxville to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
9,630 reviews

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Food

7.4

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Delta
8.0
Very good
9,630 reviews
Delta
8.0
Very good
9,630 reviews

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Food

7.4

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

United Airlines
7.4
Good
10,000 reviews
Delta
8.0
Very good
9,630 reviews

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Food

7.4

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

American Airlines
7.3
Good
10,000 reviews
Delta
8.0
Very good
9,630 reviews

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Food

7.4

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Frontier
6.2
Okay
3,835 reviews
Delta
8.0
Very good
9,630 reviews

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Food

7.4

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from Knoxville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find flights from Knoxville to St. Louis for under $300 on Cheapflights?

    Yes, there are multiple flights from Knoxville to St. Louis for under $300. The cheapest flight booked recently is on Delta for just $238, but on average you can expect to pay $355.

  • What are the cheapest airlines flying from Knoxville to St. Louis round-trip?

    Cheapflights users have booked flights from Knoxville to St. Louis round-trip from $238. Other airlines that can offer you cheap pricing are United Airlines, from $363, and American Airlines, from $418. These flights start at 21% lower than the current average price 3 months from now.

  • What does TYS to STL mean?

    This is defined as Knoxville McGhee Tyson Airport (TYS) and Lambert-St Louis Airport (STL). Codes like Lambert-St Louis Airport are often used to just call airports uniquely.

  • Can I find deals for flights from Knoxville to St. Louis that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to St. Louis flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to St. Louis with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to St. Louis flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Knoxville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to St. Louis.

  • Can I find deals for business class flights from Knoxville to St. Louis?

    Yes. Cheapflights offers flight deals from Knoxville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to St. Louis that allow pets onboard?

    Many airlines flying from Knoxville to St. Louis offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to St. Louis?

    Yes, you can often find last-minute deals on Knoxville to St. Louis flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to St. Louis flight deals updated?

    The Knoxville to St. Louis flight deals you see on this page were last updated on 7/25.

  • What is the cheapest month to book a flight from Knoxville to St. Louis?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to St. Louis (average of $312). Flying from Knoxville to St. Louis in March is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Knoxville to St. Louis

Discover the top 2 airlines that operate flights from Knoxville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,752,877 searches. Data last updated July 26, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$209Average$283FlexibilityNo cancel feeOn-time71%
DeltaCheapest$227Average$340FlexibilityNo cancel feeOn-timeN/A
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Search flights from Knoxville to St. Louis by cabin class

Find flights from Knoxville to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
First Class
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