Cheap flights from Knoxville to St. Louis (TYS - STL)

TYS — STL
Dec 6 — Dec 131

The best prices from Knoxville McGhee Tyson to Lambert-St Louis are usually found in January or February, booked 44 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

How to find the cheapest flight from Knoxville (TYS) to St. Louis (STL)

All the information you need to plan the best TYS to STL flight in 2022: compare Knoxville to St. Louis flight prices with the expected peak season, weather and rainfall in St. Louis.

TYS - STL

Price

$251 - $741

STL

Temperature

32 - 80.6 °F

STL

Rainfall

2.2 - 4.7 inches

Popular inMayHigh demand for flights, 40% potential price rise
Cheapest inJanuaryBest time to find cheap flights, 44% potential price drop
Round-trip from$251From Knoxville McGhee Tyson to Lambert-St Louis
One-way from$88One-way flight from Knoxville McGhee Tyson to Lambert-St Louis

What is the cheapest day to fly round-trip from Knoxville to St. Louis?

Saturday flights are found to be more expensive to fly from Knoxville to St. Louis. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

How far in advance should I book a flight from Knoxville to St. Louis?

Users have found that booking a flight from Knoxville to St. Louis at least 45 days early can save you up to 43% on average compared to booking a flight this week. If booking 45 days before your flight isn’t an option for you, users have found flights from Knoxville to St. Louis for as little as $466 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $521 for flights departing within the next 3 days.

What is the cheapest month to fly from Knoxville to St. Louis?

The best pricing can be found in the month of January. Prices to St. Louis from Knoxville average $447. You can even find prices in January for less than $447, as users have found deals to St. Louis from as low as $213. The month of May appears to be one of the more expensive times to travel to St. Louis from Knoxville. Flying in the targeted month can save you up to 65%.

When is the cheapest time to fly from Knoxville to St. Louis (TYS - STL)?

A simple way to save on the total cost of your ticket is to fly from Knoxville to St. Louis in the morning. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the evening.

Cheap flights from Knoxville to St. Louis in December, January 2022

The best prices found for TYS to STL flights for December, January
Dec 8 - Dec 12
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

12h 42m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 25m
$185

Frontier

Pick Dates

Deal found 11/29

Dec 9 - Dec 12
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

23h 30m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 25m
$217

Frontier

Pick Dates

Deal found 12/1

Dec 13 - Dec 15
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

12h 42m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 37m
$232

Multiple Airlines

Pick Dates

Deal found 11/29

Knoxville to St. Louis 2022 flight deals

Cheap flights to St. Louis from Knoxville found for this year
Dec 8 - Dec 12
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

12h 42m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 25m
$185

Frontier

Pick Dates

Deal found 11/29

Dec 9 - Dec 12
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

23h 30m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 25m
$217

Frontier

Pick Dates

Deal found 12/1

Dec 13 - Dec 15
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

12h 42m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 37m
$232

Multiple Airlines

Pick Dates

Deal found 11/29

Cheap American Airlines flights from Knoxville to St. Louis

Dec 28 - Jan 4
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

3h 56m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

2 stops

7h 51m
$381

American Airlines

Pick Dates

Deal found 11/30

Apr 20 - Apr 24
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

3h 50m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

3h 33m
$396

American Airlines

Pick Dates

Deal found 11/29

Jan 12 - Jan 15
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

2 stops

8h 58m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

3h 17m
$399

American Airlines

Pick Dates

Deal found 11/28

Cheap United Airlines flights from Knoxville to St. Louis

Feb 10 - Feb 13
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

25h 48m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

15h 23m
$329

United Airlines

Pick Dates

Deal found 12/1

Feb 10 - Feb 13
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

2 stops

13h 02m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

18h 58m
$339

United Airlines

Pick Dates

Deal found 12/1

Dec 24 - Dec 29
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

26h 38m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

21h 40m
$342

United Airlines

Pick Dates

Deal found 11/28

Non-stop flights to St. Louis from Knoxville

Save time with Knoxville to St. Louis direct flight deals
Dec 28 - Jan 4
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

Nonstop

2h 51m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

Nonstop

2h 51m
$4,582

Linear Air Taxi

Pick Dates

Deal found 11/30

Dec 24 - Dec 29
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

Nonstop

2h 51m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

Nonstop

2h 51m
$5,151

Linear Air Taxi

Pick Dates

Deal found 11/28

Dec 23 - Dec 28
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

Nonstop

2h 51m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

Nonstop

2h 51m
$5,921

Linear Air Taxi

Pick Dates

Deal found 11/28

Last minute flights from Knoxville to St. Louis

Late deals on return flights to St. Louis from Knoxville, departing today and this week
Dec 8 - Dec 12
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

12h 42m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 25m
$185

Frontier

Pick Dates

Deal found 11/29

Dec 9 - Dec 12
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

23h 30m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

8h 25m
$217

Frontier

Pick Dates

Deal found 12/1

Dec 7 - Dec 11
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

4h 51m
STL

Lambert-St Louis

TYS

Knoxville McGhee Tyson

1 stop

3h 58m
$475

American Airlines

Pick Dates

Deal found 11/29

One-way flights to St. Louis from Knoxville

The cheapest one-way flights from Knoxville to St. Louis
Dec 6
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

12h 42m
$88

Frontier

Pick Dates

Deal found 11/29

Dec 30
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

1 stop

4h 57m
$229

United Airlines

Pick Dates

Deal found 11/30

Jan 2
TYS

Knoxville McGhee Tyson

STL

Lambert-St Louis

2 stops

24h 39m
$241

Multiple Airlines

Pick Dates

Deal found 11/29

Related info for your journey

Useful info, stats and facts about Knoxville to St. Louis flights.

Which airlines flying from Knoxville McGhee Tyson to Lambert-St Louis have flexible cancellations due to COVID-19?

American Airlines, Delta, and United Airlines are some of the carriers that may have flexible cancellation policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

Can I find flights from Knoxville to St. Louis for under $300 on Cheapflights?

Yes, there are multiple flights from Knoxville to St. Louis for under $300. The cheapest flight booked recently is on Multiple Airlines for just $232, but on average you can expect to pay $369.

Are there nonstop flights from Knoxville to St. Louis for under $4,600 on Cheapflights?

Cheapflights has at least 11 direct flights from Knoxville to St. Louis under $4,600. A good price for a nonstop flight from Knoxville to St. Louis is less than $7,722.

Are there last-minute flights available from Knoxville to St. Louis for under $200?

There are currently 12+ open flights from Knoxville to St. Louis within the next 7 days for less than $200.

What are the cheapest airlines flying from Knoxville to St. Louis round-trip?

Cheapflights users have booked flights from Knoxville to St. Louis round-trip from $329. Another airline that can offer you cheap pricing is American Airlines. These flights start at 26% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from Knoxville to St. Louis one-way?

For one-way options, check prices for Frontier. According to our data, you can fly for as low as $88. Users have also found prices from $229 and $282 on United Airlines and American Airlines, respectively.

What are the most popular airlines that fly from Knoxville to St. Louis?

Consider American Airlines, Delta or Juneyao Airlines when booking your flight. These represent the most popular airlines when flying from Knoxville to St. Louis.

What are the cheapest flights from Knoxville to St. Louis?

Looking for the cheapest flight from Knoxville to St. Louis? While on average our users pay $504, our data indicates the cheapest price to be $277. The most popular route (Knoxville McGhee Tyson - Lambert-St Louis), is priced around $299.

Alternative routes for Knoxville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Knoxville to St. Louis

The chart below displays the airlines Cheapflights users traveling from Knoxville to St. Louis choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.
AirlineCheapestAverageFlexibilityOn-timeCOVID-19 safety
American AirlinesCheapest$261Average$445FlexibilityNo cancel feeOn-time71%COVID-19 safety
Search American Airlines flights
DeltaCheapest$279Average$417FlexibilityNo cancel feeOn-timeN/ACOVID-19 safety
Search Delta flights