$137+ Cheap flights from Syracuse to St. Louis (SYR - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
May 26 — Jun 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Syracuse to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Syracuse to St. LouisExplore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:30 pm
SYR
- STL
1 stop5h 29m
American Airlines
Tue 6/25:40 pm
STL
- SYR
1 stop5h 07m
American Airlines
Deal found 4/22![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:19 pm
SYR
- STL
1 stop5h 13m
American Airlines
Tue 7/75:02 pm
STL
- SYR
1 stop6h 18m
American Airlines
Deal found 4/26![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
SYR
- STL
1 stop5h 44m
United Airlines
Sat 7/111:13 pm
STL
- SYR
1 stop6h 56m
United Airlines
Deal found 4/23![United Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:49 pm
SYR
- STL
1 stop4h 37m
United Airlines
Tue 7/141:13 pm
STL
- SYR
1 stop6h 56m
United Airlines
Deal found 4/23![United Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:20 am
SYR
- STL
1 stop4h 09m
Delta
Sun 6/75:42 pm
STL
- SYR
1 stop5h 01m
Delta
Deal found 4/23![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
SYR
- STL
1 stop7h 20m
Delta
Sun 5/176:00 am
STL
- SYR
1 stop4h 54m
Delta
Deal found 4/23![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 am
SYR
- STL
1 stop5h 33m
United Airlines
Sun 5/107:45 am
STL
- SYR
1 stop4h 46m
United Airlines
Deal found 4/23![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:19 am
SYR
- STL
1 stop4h 13m
Delta
Sat 6/208:00 am
STL
- SYR
1 stop6h 17m
Delta
Deal found 4/22![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:03 am
SYR
- STL
1 stop4h 58m
American Airlines
Mon 7/135:02 pm
STL
- SYR
1 stop6h 18m
American Airlines
Deal found 4/24![American Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:19 am
SYR
- STL
1 stop4h 13m
Delta
Mon 6/226:10 pm
STL
- SYR
1 stop3h 52m
Delta
Deal found 4/22![Delta logo]()
$374
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:10 am
SYR
- STL
1 stop7h 38m
American Airlines
Wed 5/135:51 am
STL
- SYR
1 stop4h 09m
American Airlines
Deal found 4/21![American Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:54 pm
SYR
- STL
1 stop6h 02m
Delta
Sun 6/285:42 pm
STL
- SYR
1 stop5h 01m
Delta
Deal found 4/23![Delta logo]()
$383
Best flights from Syracuse to St. LouisDiscover carefully curated flight deals from Syracuse to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
Discover carefully curated flight deals from Syracuse to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:19 am
SYR
- STL
1 stop4h 13m
Delta
Sat 6/276:30 am
STL
- SYR
1 stop5h 29m
Delta
Deal found 4/22![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:15 am
SYR
- STL
1 stop6h 56m
United Airlines
Mon 6/151:13 pm
STL
- SYR
2 stops9h 46m
United Airlines
Deal found 4/26![United Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:40 pm
SYR
- STL
1 stop4h 29m
Delta
Sun 5/246:04 pm
STL
- SYR
1 stop4h 45m
Delta
Deal found 4/25![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:54 pm
SYR
- STL
1 stop5h 59m
Delta
Mon 7/206:04 pm
STL
- SYR
1 stop3h 54m
Delta
Deal found 4/26![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:19 am
SYR
- STL
1 stop4h 13m
Delta
Sun 6/213:45 pm
STL
- SYR
1 stop7h 16m
Delta
Deal found 4/22![Delta logo]()
$415
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:44 pm
SYR
- STL
1 stop4h 32m
United Airlines
Sat 6/278:00 am
STL
- SYR
2 stops14h 59m
United Airlines
Deal found 4/22![United Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:00 am
SYR
- STL
1 stop4h 43m
Delta
Thu 7/303:40 pm
STL
- SYR
1 stop7h 18m
Delta
Deal found 4/21![Delta logo]()
$424
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
SYR
- STL
2 stops7h 11m
United Airlines
Mon 7/139:23 am
STL
- SYR
1 stop6h 25m
United Airlines
Deal found 4/24![United Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:44 pm
SYR
- STL
1 stop4h 38m
United Airlines
Tue 8/187:01 am
STL
- SYR
3 stops25h 42m
United Airlines
Deal found 4/23![United Airlines logo]()
$562
Last-minute flights from Syracuse to St. LouisDiscover last-minute flight deals from Syracuse to St. Louis. Data last updated April 26, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to St. Louis. Data last updated April 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:10 am
SYR
- STL
1 stop7h 38m
American Airlines
Mon 4/273:43 pm
STL
- SYR
1 stop6h 59m
American Airlines
Deal found 4/22![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:30 am
SYR
- STL
1 stop6h 11m
American Airlines
Wed 5/66:29 am
STL
- SYR
1 stop6h 58m
American Airlines
Deal found 4/23![American Airlines logo]()
$431
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:45 pm
SYR
- STL
1 stop4h 28m
United Airlines
Sat 5/93:20 pm
STL
- SYR
2 stops7h 10m
United Airlines
Deal found 4/22![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
SYR
- STL
1 stop5h 44m
United Airlines
Sat 7/111:13 pm
STL
- SYR
1 stop6h 56m
United Airlines
Deal found 4/23![United Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
SYR
- STL
1 stop7h 20m
Delta
Sun 5/176:00 am
STL
- SYR
1 stop4h 54m
Delta
Deal found 4/23![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 am
SYR
- STL
1 stop5h 33m
United Airlines
Sun 5/107:45 am
STL
- SYR
1 stop4h 46m
United Airlines
Deal found 4/23![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:26 pm
SYR
- STL
2 stops49h 05m
Multiple Airlines
Thu 5/284:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:15 am
SYR
- STL
1 stop6h 56m
United Airlines
Sun 5/241:13 pm
STL
- SYR
1 stop7h 06m
United Airlines
Deal found 4/23![United Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:22 pm
SYR
- STL
2 stops21h 33m
Multiple Airlines
Sun 5/244:19 pm
STL
- SYR
1 stop16h 12m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:01 pm
SYR
- STL
1 stop6h 19m
American Airlines
Fri 5/297:50 pm
STL
- SYR
1 stop13h 32m
American Airlines
Deal found 4/23![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:30 pm
SYR
- STL
1 stop5h 29m
American Airlines
Tue 6/25:40 pm
STL
- SYR
1 stop5h 07m
American Airlines
Deal found 4/22![American Airlines logo]()
$291
One-way flights from Syracuse to St. LouisSearch for one-way flight options from Syracuse to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
Search for one-way flight options from Syracuse to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:26 pm
SYR
- STL
2 stops47h 07m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:03 pm
SYR
- STL
2 stops39h 52m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:09 pm
SYR
- STL
2 stops23h 27m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:09 pm
SYR
- STL
2 stops23h 27m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:23 pm
SYR
- STL
2 stops26h 13m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:44 pm
SYR
- STL
2 stops27h 49m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:44 pm
SYR
- STL
3 stops27h 10m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:03 pm
SYR
- STL
3 stops55h 18m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$221
Find flight deals from Syracuse to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (American Airlines) |
One-way from | $137 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $423 |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Sat 6/13
6:19 am-9:32 am
1 stop4h 13m
Lambert-St Louis
Sat 6/27
6:30 am-12:59 pm
1 stop5h 29m
$291
Quickest round-trip
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Fri 5/22
5:40 pm-9:09 pm
1 stop4h 29m
Lambert-St Louis
Sun 5/24
6:04 pm-11:49 pm
1 stop4h 45m
$329
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Thu 7/16
6:54 pm-11:53 pm
1 stop5h 59m
Lambert-St Louis
Mon 7/20
6:04 pm-10:58 pm
1 stop3h 54m
$329
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Sat 6/20
6:19 am-9:32 am
1 stop4h 13m
Lambert-St Louis
Sun 6/21
3:45 pm-12:01 am
1 stop7h 16m
$415
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Mon 7/20
6:00 am-9:43 am
1 stop4h 43m
Lambert-St Louis
Thu 7/30
3:40 pm-11:58 pm
1 stop7h 18m
$424
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Fri 6/12
6:15 am-12:11 pm
1 stop6h 56m
Lambert-St Louis
Mon 6/15
1:13 pm-11:59 pm
2 stops9h 46m
$537
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Sat 6/13
5:44 pm-9:16 pm
1 stop4h 32m
Lambert-St Louis
Sat 6/27
8:00 am-11:59 pm
2 stops14h 59m
$537
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Wed 7/8
6:00 am-12:11 pm
2 stops7h 11m
Lambert-St Louis
Mon 7/13
9:23 am-4:48 pm
1 stop6h 25m
$540
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Sat 8/15
5:44 pm-9:22 pm
1 stop4h 38m
Lambert-St Louis
Tue 8/18
7:01 am-9:43 am
3 stops25h 42m
$562
Cheapest one-way
SyracuseSt. Louis
SYR - STL
SYRSTL
Syracuse Hancock Intl
Sun 5/31
7:26 pm-5:33 pm
2 stops47h 07m
$137
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Syracuse to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to St. Louis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Syracuse-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Syracuse with our price prediction graph.
SYR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to St. Louis
How far ahead should I book a flight from Syracuse to St. Louis?
To ensure you get the cheapest price possible for a flight from Syracuse to St. Louis, you should look to book at least 23 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Syracuse to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $283). Flying from Syracuse to St. Louis in March is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Syracuse to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 26, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Syracuse to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Syracuse
Popular flights
St. Louis flight routes
Alternative routes for Syracuse to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Syracuse to St. Louis by cabin class
Find flights from Syracuse to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Syracuse and St. Louis flights
Browse other Syracuse and St. Louis flight options. Last updated on April 26, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on April 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 26, 2026.
Top 3 airlines flying from Syracuse to St. Louis
Discover the top 3 airlines that operate flights from Syracuse to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$318 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$357 | FlexibilityNo cancel fee | On-timeN/A |