St. Louis

$69+ Cheap flights from Fort Myers to St. Louis (RSW - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — STL
Jul 7 — Jul 141
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Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in July or May, booked 58 days in advance, depart on a Thursday or Wednesday and return on a Wednesday

Cheap flight deals from Fort Myers to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2025.

Round-trip from

$137
(Southwest)

One-way from

$69
(Southwest)

Popular in

February

Cheapest in

July

Average price

$282
From Fort Myers SW Florida Intl to Lambert-St Louis
One-way flight from Fort Myers SW Florida Intl to Lambert-St Louis
Highest demand for flights based on searches. 11% potential increase in price ($53 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/88:00 amRSW - STL
Nonstop2h 35mSouthwest
Mon 10/138:25 pmSTL - RSW
Nonstop2h 20mSouthwest
Deal found 6/30$157
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/218:23 amRSW - STL
1 stop4h 48mAmerican Airlines
Mon 8/256:00 amSTL - RSW
1 stop7h 45mAmerican Airlines
Deal found 6/30$177
This FlightHub deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/25:58 pmRSW - STL
1 stop16h 54mSpirit Airlines
Mon 8/410:47 amSTL - RSW
1 stop6h 38mSpirit Airlines
Deal found 6/30$199
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/205:40 amRSW - STL
1 stop5h 01mDelta
Wed 7/235:23 pmSTL - RSW
1 stop6h 22mDelta
Deal found 6/30$207
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/29:34 pmRSW - STL
2 stops20h 11mMultiple Airlines
Mon 8/410:47 amSTL - RSW
1 stop6h 38mMultiple Airlines
Deal found 6/30$255
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/24:36 pmRSW - STL
1 stop5h 59mUnited Airlines
Thu 7/311:25 amSTL - RSW
2 stops9h 35mUnited Airlines
Deal found 6/29$384

Cheapflights Fare Finder

Customize your flight search to find flights from Fort Myers to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

Fly from

Fort Myers

Fly to

St. Louis

Route

Depart

Return

Price

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 8/26

6:20 pm-7:55 pm

Nonstop2h 35m

Lambert-St Louis

Thu 8/28

7:55 am-11:20 am

Nonstop2h 25m

$137

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 8/21

2:33 pm-8:23 pm

1 stop6h 50m

Lambert-St Louis

Mon 8/25

3:53 pm-10:27 pm

1 stop5h 34m

$177

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 8/5

1:10 pm-6:47 pm

1 stop6h 37m

Lambert-St Louis

Sat 8/9

7:00 am-12:05 pm

1 stop4h 05m

$202

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 8/6

5:37 pm-1:34 pm

2 stops20h 57m

Lambert-St Louis

Wed 8/13

5:40 pm-6:20 pm

2 stops23h 40m

$277

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 7/16

8:17 pm-12:10 pm

2 stops16h 53m

Lambert-St Louis

Sun 7/20

10:47 am-6:25 pm

1 stop6h 38m

$311

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 8/6

7:15 am-12:27 pm

1 stop6h 12m

Lambert-St Louis

Wed 8/13

5:00 am-11:16 am

1 stop5h 16m

$345

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Mon 7/21

9:34 pm-4:31 pm

2 stops19h 57m

Lambert-St Louis

Wed 7/23

11:24 am-6:25 pm

3 stops30h 01m

$462

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Sun 9/7

7:50 am-9:20 am

Nonstop2h 30m

$69

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Mon 9/8

11:57 am-5:17 pm

1 stop6h 20m

$89

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Mon 8/4

7:55 pm-11:53 pm

1 stop4h 58m

$94

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Showing 1-10 of 13 results
1
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The best insider tips for Fort Myers to St. Louis flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Fort Myers to St. Louis trip
Airports
RSW

During peak tourist seasons, plan an extra 20 minutes at RSW for check-in due to smaller airline ticket counters.

Read more about RSWby Matt Meltzer
STL

Use the MetroLink light rail for a convenient and economical way to reach downtown St. Louis from STL.

Read more about STLby Taryn White
Our travel experts
Matt Meltzer

Matt Meltzer

Expert on RSW

Matt Meltzer

Matt Meltzer

Matt Meltzer has been a travel writer for over a decade, covering U.S. domestic locations and hotels for Thrillist, Fifty Grande, Matador Network, Conde Nast Traveler, and other top publications. He's won multiple travel journalism awards from the Society of American Travel Writers and North American Travel Journalists Association, and currently resides in South Florida.

Read more
Taryn White

Taryn White

Expert on STL

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to St. Louis. Price data was last updated on June 27, 2025.

The best time to book flights from Fort Myers to St. Louis is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Fort Myers to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $311). Flying from Fort Myers to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to STL?

Find hourly flight availability from Fort Myers to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

One of the essential ways to save on airfare from Fort Myers to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 12% on airfare.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 2, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Fort Myers to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
8.0
Very good

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.2

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Fort Myers to St. Louis?

    If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There is 1 flight from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 30m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.

  • How popular is this Fort Myers to St. Louis flight route?

  • What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

    Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $137. Additional round-trip tickets that might be worth considering are offered by American Airlines and Spirit Airlines, with the lowest prices starting at $177 and $199, respectively. Users have found that Southwest is 65% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $69. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Fort Myers to St. Louis for a low price.

  • What are the cheapest flights from Fort Myers to St. Louis?

    While on average a flight from Fort Myers to St. Louis is generally $294, our data shows the cheapest flight currently is $89. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $157 for that flight.

  • Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

    Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.

  • Can I find deals for business class flights from Fort Myers to St. Louis?

    Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $311). Flying from Fort Myers to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Festus
Chesterfield
Farmington

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Alternative routes for Fort Myers to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Fort Myers to St. Louis

Discover the top 3 airlines that operate flights from Fort Myers to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$211Average$332FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$243Average$381FlexibilityNo cancel feeOn-time63%

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