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Missouri

$80+ Cheap flights from Fort Myers (RSW) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — STL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Fort Myers to Missouri

Cheapest flights from Fort Myers to Missouri
Explore the most affordable flight options available from Fort Myers to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:40 pmRSW - STL
1 stop17h 22mFrontier
Mon 12/227:43 pmSTL - RSW
1 stop20h 01mFrontier
Deal found 12/3$247
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amRSW - SGF
1 stop8h 38mUnited Airlines
Sun 1/411:24 amSGF - RSW
1 stop6h 05mUnited Airlines
Deal found 12/3$329
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:37 pmRSW - STL
1 stop5h 56mDelta
Thu 12/187:05 amSTL - RSW
1 stop6h 58mDelta
Deal found 12/1$343
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:34 amRSW - STL
2 stops8h 03mAmerican Airlines
Thu 12/182:04 pmSTL - RSW
1 stop5h 36mAmerican Airlines
Deal found 12/1$348
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:00 amRSW - SGF
1 stop7h 55mUnited Airlines
Sun 1/49:00 amSGF - RSW
1 stop6h 02mUnited Airlines
Deal found 12/4$354
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:48 pmRSW - SGF
1 stop7h 16mAmerican Airlines
Sat 1/36:24 pmSGF - RSW
1 stop4h 59mAmerican Airlines
Deal found 12/4$363
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:52 pmRSW - SGF
1 stop7h 34mAmerican Airlines
Sat 12/62:02 pmSGF - RSW
1 stop8h 52mAmerican Airlines
Deal found 12/2$369
This Southwest deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:10 pmRSW - STL
1 stop5h 15mSouthwest
Thu 12/183:00 pmSTL - RSW
Nonstop2h 25mSouthwest
Deal found 12/1$377
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:37 pmRSW - MCI
1 stop4h 53mDelta
Tue 12/167:00 amMCI - RSW
1 stop7h 03mDelta
Deal found 12/1$413
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:03 pmRSW - MCI
2 stops7h 51mAmerican Airlines
Tue 12/166:00 amMCI - RSW
1 stop6h 17mAmerican Airlines
Deal found 12/1$418
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:00 amRSW - SGF
1 stop8h 04mUnited Airlines
Sun 12/213:14 pmSGF - RSW
1 stop5h 38mUnited Airlines
Deal found 12/2$424
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:38 pmRSW - STL
1 stop4h 24mDelta
Fri 12/55:12 pmSTL - RSW
1 stop4h 56mDelta
Deal found 12/1$429

Find flight deals from Fort Myers to Missouri

Keep the following information in mind while searching for Fort Myers to Missouri flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$159
(American Airlines)

One-way from

$80
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$527
Provider with most accurate pricing for Fort Myers SW Florida Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Lambert-St Louis flights.
Search Deals
From Fort Myers SW Florida Intl to Missouri
Search Deals
One-way flight from Fort Myers SW Florida Intl to Missouri
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Fort Myers to Missouri that are best for you.

Fly from

Fort Myers

Fly to

Missouri

Route

Depart

Return

Price

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 1/22

3:04 pm-9:51 pm

1 stop7h 47m

Lambert-St Louis

Tue 1/27

3:54 pm-11:33 pm

1 stop6h 39m

$159

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 1/21

6:35 pm-11:12 pm

1 stop5h 37m

Lambert-St Louis

Sat 1/24

3:54 pm-11:58 pm

1 stop7h 04m

$159

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Fri 1/30

3:04 pm-11:17 pm

1 stop9h 13m

Kansas City

Mon 2/2

3:01 pm-10:03 pm

1 stop6h 02m

$199

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 1/14

7:45 pm-6:51 am

2 stops36h 06m

Lambert-St Louis

Wed 1/21

8:22 pm-6:41 pm

1 stop21h 19m

$209

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Thu 1/22

5:35 am-9:39 am

1 stop5h 04m

Kansas City

Mon 1/26

6:18 pm-12:32 am

1 stop5h 14m

$217

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Fri 1/30

7:31 am-7:51 pm

2 stops13h 20m

Kansas City

Sun 2/1

11:00 am-6:41 pm

1 stop6h 41m

$222

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 1/22

7:36 pm-6:51 am

1 stop12h 15m

Lambert-St Louis

Sun 1/25

5:42 pm-6:50 pm

2 stops24h 08m

$229

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Wed 1/21

12:20 pm-2:45 pm

Nonstop3h 25m

Kansas City

Fri 1/23

7:35 am-5:25 pm

1 stop8h 50m

$230

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Fri 2/6

8:36 am-4:14 pm

1 stop8h 38m

Lambert-St Louis

Sun 2/8

6:00 am-4:35 pm

1 stop9h 35m

$237

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Fri 1/30

5:30 pm-10:39 pm

1 stop6h 09m

Kansas City

Sun 2/1

6:00 am-10:03 pm

1 stop15h 03m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 51 results
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Best time to book a flight from Fort Myers to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Missouri

What is the cheapest month to book a flight from Fort Myers to Missouri?

Currently, January is the cheapest month in which you can book a flight from Fort Myers to Missouri (average of $101). Flying from Fort Myers to Missouri in November is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to MO?

Find hourly flight availability from Fort Myers to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

One of the essential ways to save on airfare from Fort Myers to Missouri is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 9% on airfare.

What is the cheapest day to fly from Fort Myers to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Fort Myers to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Fort Myers to Missouri flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 4, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,250 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,011 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,047 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Missouri?

    Fort Myers SW Florida Intl (RSW) is the airport you will fly out of if you book a flight from Fort Myers to Missouri. It is only a 10.0 mi journey to SW Florida Intl (RSW) from Fort Myers’s city center.

  • How popular is this Fort Myers to Missouri flight route?

    The Fort Myers SW Florida Intl to Missouri flight path was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Fort Myers to Missouri?

    Departing from Fort Myers to Missouri will take you 5h 04m. There are 1155 mi between Fort Myers and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Fort Myers to Missouri?

    While some choose either Fort Myers SW Florida Intl - Kansas City or Fort Myers SW Florida Intl - Springfield-Branson, Fort Myers SW Florida Intl - Lambert-St Louis is the most popular route from Fort Myers to Missouri.

  • What are the cheapest flights from Fort Myers to Missouri?

    On average you can expect to pay $438 for a flight from Fort Myers to Missouri. The cheapest flight overall is $168 while the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis) is currently priced at $197.

  • Can I find deals for flights from Fort Myers to Missouri that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Missouri.

  • Can I find deals for business class flights from Fort Myers to Missouri?

    Yes. Cheapflights offers flight deals from Fort Myers to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Fort Myers to Missouri (average of $101). Flying from Fort Myers to Missouri in November is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Fort Myers to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Fort Myers to Missouri

Discover the top 3 airlines that operate flights from Fort Myers to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$158Average$452FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$177Average$406FlexibilityNo cancel feeOn-time63%
DeltaCheapest$196Average$410FlexibilityNo cancel feeOn-timeN/A

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