$109+ Cheap flights from Missouri to Fort Myers (RSW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RSW
Nov 2 — Nov 91
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Fort Myers with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to Fort MyersExplore the most affordable flight options available from Missouri to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2026.
Explore the most affordable flight options available from Missouri to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2026.
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:55 am -
Nonstop2h 25m
Mon 11/27:15 pm -
Nonstop2h 45m
Deal found 9/29![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:55 pm -
1 stop4h 50m
Thu 11/196:05 am -
Nonstop2h 35m
Deal found 9/29![Southwest logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
1 stop8h 32m
Mon 11/912:35 pm -
2 stops11h 23m
Deal found 10/1![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:15 pm -
1 stop7h 44m
Thu 11/52:32 pm -
1 stop8h 24m
Deal found 9/29![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:20 am -
2 stops11h 22m
Sat 11/216:00 am -
2 stops9h 18m
Deal found 10/1![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:15 am -
Nonstop2h 25m
Fri 11/66:10 am -
Nonstop2h 35m
Deal found 10/1![Southwest logo]()
$350
This Cheapflightsfares deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:43 pm -
1 stop19h 10m
Tue 11/245:48 pm -
1 stop26h 46m
Deal found 9/29![Frontier logo]()
$354
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:25 pm -
1 stop6h 55m
Thu 12/31:35 pm -
2 stops6h 50m
Deal found 9/28![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 am -
Nonstop2h 25m
Fri 11/67:15 pm -
Nonstop2h 45m
Deal found 9/30![Southwest logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:15 am -
1 stop5h 53m
Tue 10/204:34 pm -
1 stop7h 21m
Deal found 9/28![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:25 am -
2 stops8h 10m
Sat 11/77:05 am -
2 stops6h 35m
Deal found 10/1![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:03 am -
1 stop6h 24m
Fri 12/117:59 pm -
1 stop5h 06m
Deal found 9/27![Delta logo]()
$373
Best flights from Missouri to Fort MyersDiscover carefully curated flight deals from Missouri to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 3, 2026.
Discover carefully curated flight deals from Missouri to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 3, 2026.
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:55 am -
Nonstop2h 25m
Mon 10/266:25 pm -
1 stop6h 15m
Deal found 9/28![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am -
1 stop7h 49m
Mon 11/165:12 pm -
1 stop6h 14m
Deal found 9/28![United Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:23 pm -
1 stop6h 19m
Sun 12/68:00 am -
1 stop7h 40m
Deal found 9/30![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:20 pm -
Nonstop2h 25m
Mon 11/236:10 am -
Nonstop2h 35m
Deal found 9/28![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:25 pm -
1 stop6h 11m
Tue 10/201:12 pm -
1 stop4h 16m
Deal found 9/27![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:35 pm -
Nonstop2h 45m
Tue 11/2410:20 am -
Nonstop3h 15m
Deal found 9/29![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:00 am -
1 stop8h 02m
Sat 11/74:45 pm -
1 stop5h 38m
Deal found 10/1![United Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:14 am -
1 stop5h 40m
Tue 10/208:09 am -
1 stop6h 11m
Deal found 9/29![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:55 am -
2 stops9h 10m
Thu 12/315:40 pm -
1 stop5h 45m
Deal found 10/1![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/231:41 pm -
1 stop8h 27m
Wed 1/2711:45 am -
1 stop9h 49m
Deal found 9/30![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:56 pm -
1 stop5h 17m
Wed 11/117:00 am -
1 stop8h 07m
Deal found 9/30![United Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:55 pm -
Nonstop2h 25m
Tue 11/249:20 pm -
Nonstop2h 45m
Deal found 10/2![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:15 am -
1 stop7h 42m
Mon 10/264:45 pm -
1 stop7h 13m
Deal found 9/30![United Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:54 pm -
1 stop4h 46m
Tue 12/15:20 am -
1 stop7h 55m
Deal found 10/2![Delta logo]()
$512
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:35 am -
1 stop5h 25m
Tue 11/175:40 pm -
Nonstop2h 40m
Deal found 10/2![Southwest logo]()
$437
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:20 am -
2 stops11h 22m
Thu 11/191:05 pm -
2 stops10h 53m
Deal found 10/1![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:31 pm -
1 stop6h 09m
Mon 11/305:30 am -
1 stop4h 57m
Deal found 10/2![Delta logo]()
$532
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:50 am -
1 stop7h 05m
Thu 11/59:20 am -
Nonstop3h 10m
Deal found 9/27![Southwest logo]()
$448
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops10h 49m
Sun 11/226:00 am -
2 stops9h 18m
Deal found 10/1![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:20 am -
1 stop6h 40m
Fri 10/301:45 pm -
Nonstop2h 35m
Deal found 9/29![Southwest logo]()
$455
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:15 am -
2 stops11h 18m
Tue 10/2012:16 pm -
2 stops11h 39m
Deal found 9/28![United Airlines logo]()
$465
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:05 pm -
1 stop4h 45m
Fri 12/411:50 am -
Nonstop3h 10m
Deal found 9/30![Southwest logo]()
$476
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:00 am -
1 stop8h 32m
Tue 11/244:45 pm -
1 stop7h 13m
Deal found 10/1![United Airlines logo]()
$504
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:25 am -
2 stops7h 35m
Tue 11/310:35 am -
2 stops7h 20m
Deal found 9/29![Southwest logo]()
$482
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 am -
1 stop7h 19m
Wed 11/182:21 pm -
1 stop6h 22m
Deal found 10/1![United Airlines logo]()
$509
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:50 pm -
1 stop5h 50m
Mon 11/239:20 am -
Nonstop3h 10m
Deal found 9/29![Southwest logo]()
$492
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:00 am -
2 stops12h 50m
Thu 11/191:05 pm -
2 stops10h 53m
Deal found 10/1![United Airlines logo]()
$514
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:50 am -
2 stops10h 50m
Sun 11/225:30 pm -
2 stops6h 30m
Deal found 9/29![Southwest logo]()
$533
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:15 am -
1 stop7h 42m
Tue 10/2712:06 pm -
2 stops11h 52m
Deal found 9/28![United Airlines logo]()
$592
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:35 pm -
2 stops6h 25m
Mon 10/196:25 pm -
1 stop6h 30m
Deal found 9/30![Southwest logo]()
$564
Last-minute flights from Missouri to Fort MyersDiscover last-minute flight deals from Missouri to Fort Myers. Data last updated October 3, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Fort Myers. Data last updated October 3, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:15 am -
1 stop5h 53m
Tue 10/204:34 pm -
1 stop7h 21m
Deal found 9/28![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:50 pm -
Nonstop2h 45m
Mon 10/268:05 am -
Nonstop3h 05m
Deal found 9/29![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:55 am -
Nonstop2h 25m
Mon 11/27:15 pm -
Nonstop2h 45m
Deal found 9/29![Southwest logo]()
$337
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:15 pm -
1 stop7h 44m
Thu 11/52:32 pm -
1 stop8h 24m
Deal found 9/29![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 am -
Nonstop2h 25m
Fri 11/67:15 pm -
Nonstop2h 45m
Deal found 9/30![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:25 am -
2 stops8h 10m
Sat 11/77:05 am -
2 stops6h 35m
Deal found 10/1![Southwest logo]()
$367
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:15 am -
Nonstop2h 25m
Fri 11/66:10 am -
Nonstop2h 35m
Deal found 10/1![Southwest logo]()
$350
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
1 stop8h 32m
Mon 11/912:35 pm -
2 stops11h 23m
Deal found 10/1![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:55 pm -
1 stop4h 50m
Thu 11/196:05 am -
Nonstop2h 35m
Deal found 9/29![Southwest logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:20 am -
2 stops11h 22m
Sat 11/216:00 am -
2 stops9h 18m
Deal found 10/1![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:30 am -
Nonstop2h 20m
Tue 11/249:20 pm -
Nonstop2h 45m
Deal found 9/29![Southwest logo]()
$382
This Cheapflightsfares deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:43 pm -
1 stop19h 10m
Tue 11/245:48 pm -
1 stop26h 46m
Deal found 9/29![Frontier logo]()
$354
One-way flights from Missouri to Fort MyersSearch for one-way flight options from Missouri to Fort Myers. Find affordable one-way fares based on user searches. Data last updated October 3, 2026.
Search for one-way flight options from Missouri to Fort Myers. Find affordable one-way fares based on user searches. Data last updated October 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:44 pm -
2 stops20h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:02 pm -
2 stops28h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:44 pm -
2 stops38h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:44 pm -
2 stops28h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:44 pm -
2 stops26h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:02 pm -
2 stops35h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:44 pm -
2 stops28h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:44 pm -
2 stops26h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:44 pm -
2 stops26h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:35 pm -
2 stops40h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:32 pm -
2 stops37h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:43 pm -
2 stops24h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$176
Find flight deals from Missouri to Fort Myers
Keep the following information in mind while searching for Missouri to Fort Myers flight deals. Data was last updated October 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (Southwest) |
One-way from | $109 (Kiwi.com) |
Popular in | November |
Cheapest in | October |
Average price | $382 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
Use the filters below to find and compare flights from Missouri to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisFort Myers
STL Lambert-St Louis - RSW Fort Myers SW Florida Intl
STLRSW
Lambert-St Louis
Sat 12/5
5:05 pm-8:30 pm
Nonstop2h 25m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$169
St. LouisFort Myers
STL Lambert-St Louis - RSW Fort Myers SW Florida Intl
STLRSW
Lambert-St Louis
Tue 12/1
12:36 pm-6:51 pm
1 stop5h 15m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
St. LouisFort Myers
STL Lambert-St Louis - RSW Fort Myers SW Florida Intl
STLRSW
Lambert-St Louis
Thu 10/29
7:20 pm-12:21 am
1 stop4h 01m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
St. LouisFort Myers
STL Lambert-St Louis - RSW Fort Myers SW Florida Intl
STLRSW
Lambert-St Louis
Wed 10/28
10:14 am-4:54 pm
1 stop5h 40m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
St. LouisFort Myers
STL Lambert-St Louis - RSW Fort Myers SW Florida Intl
STLRSW
Lambert-St Louis
Fri 10/30
6:00 am-12:07 pm
1 stop5h 07m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$187
St. LouisFort Myers
STL Lambert-St Louis - RSW Fort Myers SW Florida Intl
STLRSW
Lambert-St Louis
Fri 1/1
4:49 pm-11:21 pm
1 stop5h 32m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$187
Kansas CityFort Myers
MCI Kansas City - RSW Fort Myers SW Florida Intl
MCIRSW
Kansas City
Thu 10/22
6:19 am-1:01 pm
1 stop5h 42m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$200
Kansas CityFort Myers
MCI Kansas City - RSW Fort Myers SW Florida Intl
MCIRSW
Kansas City
Wed 10/21
5:25 am-11:35 am
1 stop5h 10m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$200
Kansas CityFort Myers
MCI Kansas City - RSW Fort Myers SW Florida Intl
MCIRSW
Kansas City
Thu 10/29
3:35 pm-11:00 pm
2 stops6h 25m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$205
Kansas CityFort Myers
MCI Kansas City - RSW Fort Myers SW Florida Intl
MCIRSW
Kansas City
Thu 10/22
1:50 pm-11:55 pm
1 stop9h 05m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$205
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Missouri with our price prediction graph.
STL-RSW
MCI-RSW
COU-RSW
SGF-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Fort Myers
USMO-RSW
STL-RSW
MCI-RSW
COU-RSW
SGF-RSW
What is the cheapest month to book a flight from Missouri to Fort Myers?
Currently, January is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $393). Flying from Missouri to Fort Myers in November is currently the most expensive (average of $552). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to RSW?
Find hourly flight availability from Missouri to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 3, 2026.
One of the essential ways to save on airfare from Missouri to Fort Myers is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 39% on airfare.
How much does it cost to fly round-trip from Missouri to Fort Myers?
Airfare is typical for this route at the moment.
Missouri to Fort Myers flights typically cost between $317 and $483 in October.The cheapest round-trip price found within the last 5 days was $337 on Southwest (Oct 26-Nov 2).
How far ahead should I book a flight from Missouri to Fort Myers?
The best time to book flights from Missouri to Fort Myers is 53 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Missouri to Fort Myers?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Fort Myers. Price data was last updated on May 23, 2026.
Travelers seeking maximum savings on their Missouri to Fort Myers flight should consider departing on Thursday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Fort Myers?
Book flights to Fort Myers if you plan to visit one of these locationsNorth Fort Myers
Lehigh Acres
Sanibel
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Alternative routes for Missouri to Fort Myers
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Complete your trip
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Search flights from Missouri to Fort Myers by cabin class
Find flights from Missouri to Fort Myers, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Fort Myers flights
Browse other Missouri and Fort Myers flight options. Last updated on October 3, 2026.
Popular flight searches
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Missouri to Fort Myers flights
Consider these flights traveling from Missouri to Fort Myers.
Top 4 airlines flying from Missouri to Fort Myers
Discover the top 4 airlines that operate flights from Missouri to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$421 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$258 | Average$446 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$305 | Average$479 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$306 | Average$447 | FlexibilityNo cancel fee | On-timeN/A |