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Fort Myers

$124+ Cheap flights from Missouri to Fort Myers (RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RSW
Jun 2 — Jun 91
Tue 6/2
Tue 6/9
1 adult, Economy
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Cheap flight deals from Missouri to Fort Myers

Cheapest flights from Missouri to Fort Myers
Explore the most affordable flight options available from Missouri to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:11 pm
SGF
-
RSW
1 stop8h 18m
American Airlines
Tue 7/1411:35 am
RSW
-
SGF
1 stop8h 43m
American Airlines
Deal found 4/28$315
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
SGF
-
RSW
1 stop5h 01m
Delta
Thu 10/298:10 am
RSW
-
SGF
1 stop7h 40m
Delta
Deal found 4/28$324
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:58 pm
SGF
-
RSW
1 stop5h 04m
Delta
Tue 6/233:41 pm
RSW
-
SGF
1 stop7h 28m
Delta
Deal found 4/28$337
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:49 pm
SGF
-
RSW
1 stop4h 38m
Delta
Fri 6/56:45 am
RSW
-
SGF
1 stop5h 42m
Delta
Deal found 5/1$344
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:53 am
STL
-
RSW
1 stop13h 19m
Delta
Tue 6/97:00 am
RSW
-
STL
1 stop17h 23m
Delta
Deal found 5/2$345
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:30 am
STL
-
RSW
1 stop6h 36m
American Airlines
Thu 6/45:19 pm
RSW
-
STL
1 stop7h 57m
American Airlines
Deal found 4/29$353
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:53 pm
SGF
-
RSW
1 stop5h 07m
Delta
Sun 7/195:35 am
RSW
-
SGF
1 stop6h 17m
Delta
Deal found 5/2$353
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:58 pm
STL
-
RSW
1 stop23h 16m
Multiple Airlines
Tue 8/258:00 am
RSW
-
STL
2 stops25h 52m
Multiple Airlines
Deal found 5/2$355
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:45 pm
STL
-
RSW
Nonstop2h 25m
Southwest
Tue 6/26:15 pm
RSW
-
STL
Nonstop2h 45m
Southwest
Deal found 4/28$357
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:58 pm
SGF
-
RSW
1 stop5h 04m
Delta
Sun 6/215:37 am
RSW
-
SGF
1 stop6h 15m
Delta
Deal found 4/28$357
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
STL
-
RSW
2 stops8h 06m
American Airlines
Tue 6/26:15 am
RSW
-
STL
1 stop8h 00m
American Airlines
Deal found 4/28$358
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:12 pm
STL
-
RSW
1 stop4h 50m
Delta
Tue 6/237:00 am
RSW
-
STL
1 stop9h 16m
Delta
Deal found 4/29$361

Find flight deals from Missouri to Fort Myers

Keep the following information in mind while searching for Missouri to Fort Myers flight deals. Data was last updated May 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$315
(American Airlines)

One-way from

$124
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$417
Provider with most accurate pricing for Lambert-St Louis-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Fort Myers SW Florida Intl flights.
Search Deals
From Missouri to Fort Myers SW Florida Intl
Search Deals
One-way flight from Missouri to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Missouri to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Tue 6/16

7:10 pm-10:35 pm

Nonstop2h 25m

Fort Myers SW Florida Intl

Tue 6/23

2:30 pm-8:20 pm

1 stop6h 50m

$367

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Tue 8/18

1:40 pm-8:10 pm

1 stop5h 30m

Fort Myers SW Florida Intl

Tue 8/25

6:15 pm-7:50 pm

Nonstop2h 35m

$367

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Mon 6/1

7:05 am-12:19 pm

1 stop4h 14m

Fort Myers SW Florida Intl

Sat 6/6

5:35 am-8:48 am

1 stop4h 13m

$389

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 5/29

2:54 pm-9:59 pm

1 stop6h 05m

Fort Myers SW Florida Intl

Fri 6/5

12:59 pm-11:27 pm

2 stops11h 28m

$419
Quickest round-trip

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Sat 6/6

6:50 pm-10:15 pm

Nonstop2h 25m

Fort Myers SW Florida Intl

Sun 6/7

8:45 pm-11:55 pm

1 stop4h 10m

$430

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Thu 6/4

8:00 pm-11:25 pm

Nonstop2h 25m

Fort Myers SW Florida Intl

Thu 6/11

6:15 am-10:20 am

1 stop5h 05m

$430

Kansas CityFort Myers

MCI - RSW

MCIRSW

Kansas City

Sat 9/12

2:25 pm-7:45 pm

1 stop4h 20m

Fort Myers SW Florida Intl

Tue 9/22

8:45 am-2:10 pm

1 stop6h 25m

$438

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Tue 9/22

10:45 am-8:10 pm

2 stops8h 25m

Fort Myers SW Florida Intl

Fri 9/25

10:15 am-9:55 pm

2 stops12h 40m

$439

Kansas CityFort Myers

MCI - RSW

MCIRSW

Kansas City

Tue 6/30

7:53 am-2:44 pm

1 stop5h 51m

Fort Myers SW Florida Intl

Tue 7/7

7:00 am-4:22 pm

2 stops10h 22m

$443

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Wed 5/27

6:00 am-5:23 pm

2 stops10h 23m

Fort Myers SW Florida Intl

Wed 6/3

11:59 am-9:16 pm

2 stops10h 17m

$466

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 53 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Fort Myers

How far ahead should I book a flight from Missouri to Fort Myers?

The best time to book flights from Missouri to Fort Myers is 53 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Missouri to Fort Myers?

Currently, March is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $105). Flying from Missouri to Fort Myers in April is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to RSW?

Find hourly flight availability from Missouri to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 3, 2026.

One of the essential ways to save on airfare from Missouri to Fort Myers is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 36% on airfare.

What is the cheapest day to fly from Missouri to Fort Myers?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Fort Myers. Price data was last updated on April 25, 2026.

Travelers seeking maximum savings on their Missouri to Fort Myers flight should consider departing on Thursday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Missouri to Fort Myers?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Fort Myers from Missouri?

    Fort Myers SW Florida Intl (RSW) is the airport you will fly into if you book a flight from Missouri to Fort Myers. It is only a 10.0 mi journey from SW Florida Intl (RSW) to Fort Myers’s city center.

  • How popular is this Missouri to Fort Myers flight route?

    The Missouri to Fort Myers SW Florida Intl flight path was viewed by 9 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Fort Myers?

    A quick flight from Missouri to Fort Myers can take about 2h 25m. Southwest provides one of the quickest options available for as low as $367. The distance from Missouri to Fort Myers is about 980 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Fort Myers one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $79. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Missouri to Fort Myers for a low price.

  • What are the most popular routes from Missouri to Fort Myers?

    While some choose either Kansas City - Fort Myers SW Florida Intl or Springfield-Branson - Fort Myers SW Florida Intl, Lambert-St Louis - Fort Myers SW Florida Intl is the most popular route from Missouri to Fort Myers.

  • What are the cheapest flights from Missouri to Fort Myers?

    The cheapest flight price from Missouri to Fort Myers is $228. On average you can expect to pay $406. The most popular route, (Lambert-St Louis - Fort Myers SW Florida Intl), can usually be booked for $367.

  • Can I find deals for flights from Missouri to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Missouri to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Fort Myers.

  • Can I find deals for business class flights from Missouri to Fort Myers?

    Yes. Cheapflights offers flight deals from Missouri to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Fort Myers?

    Currently, March is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $105). Flying from Missouri to Fort Myers in April is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
North Fort Myers
Estero
Sanibel

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Top 4 airlines flying from Missouri to Fort Myers

Discover the top 4 airlines that operate flights from Missouri to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$150Average$396FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$189Average$450FlexibilityNo cancel feeOn-time63%
DeltaCheapest$194Average$382FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$404FlexibilityNo cancel feeOn-time71%

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