$333+ Cheap flights from Gainesville to St. Louis (GNV - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — STL
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Gainesville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Gainesville to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Gainesville to St. LouisExplore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:33 am -
1 stop6h 30m
Wed 9/2310:21 am -
1 stop4h 37m
Deal found 9/4![American Airlines logo]()
$453
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:13 pm -
1 stop7h 29m
Mon 10/126:07 pm -
1 stop4h 52m
Deal found 9/2![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:39 pm -
1 stop7h 03m
Fri 10/96:07 pm -
1 stop4h 52m
Deal found 9/4![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:20 pm -
1 stop5h 37m
Mon 9/218:30 am -
1 stop7h 17m
Deal found 9/2![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:10 pm -
1 stop7h 23m
Thu 11/129:08 am -
1 stop4h 37m
Deal found 9/4![American Airlines logo]()
$665
Best flights from Gainesville to St. LouisDiscover carefully curated flight deals from Gainesville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Gainesville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:33 am -
1 stop6h 30m
Wed 9/2310:21 am -
1 stop4h 37m
Deal found 9/4![American Airlines logo]()
$453
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:13 pm -
1 stop5h 46m
Sun 10/256:07 pm -
1 stop4h 52m
Deal found 9/4![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:13 pm -
1 stop7h 29m
Mon 10/126:07 pm -
1 stop4h 52m
Deal found 9/2![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:05 am -
1 stop3h 55m
Fri 9/256:00 am -
1 stop5h 39m
Deal found 9/6![Delta logo]()
$1,022
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:39 pm -
1 stop7h 03m
Fri 10/96:07 pm -
1 stop4h 52m
Deal found 9/4![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:20 pm -
1 stop5h 37m
Mon 9/218:30 am -
1 stop7h 17m
Deal found 9/2![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:33 am -
2 stops9h 49m
Thu 11/126:47 am -
1 stop5h 27m
Deal found 9/7![American Airlines logo]()
$700
Last-minute flights from Gainesville to St. LouisDiscover last-minute flight deals from Gainesville to St. Louis. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to St. Louis. Data last updated September 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:20 pm -
1 stop5h 37m
Mon 9/218:30 am -
1 stop7h 17m
Deal found 9/2![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:33 am -
1 stop6h 30m
Wed 9/2310:21 am -
1 stop4h 37m
Deal found 9/4![American Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:05 am -
1 stop3h 55m
Fri 9/256:00 am -
1 stop5h 39m
Deal found 9/6![Delta logo]()
$1,022
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:39 pm -
1 stop7h 03m
Fri 10/96:07 pm -
1 stop4h 52m
Deal found 9/4![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:13 pm -
1 stop7h 29m
Mon 10/126:07 pm -
1 stop4h 52m
Deal found 9/2![American Airlines logo]()
$457
One-way flights from Gainesville to St. LouisSearch for one-way flight options from Gainesville to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Gainesville to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:10 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:19 am -
1 stop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Delta logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:39 pm -
1 stop7h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:44 am -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:20 pm -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
2 stops7h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$537
Find flight deals from Gainesville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $453 (American Airlines) |
One-way from | $333 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Mon 10/19
7:03 pm-11:54 pm
1 stop5h 51m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$333
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Tue 12/1
5:10 pm-11:35 pm
1 stop7h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$333
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Sun 10/18
6:30 pm-11:42 pm
1 stop6h 12m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$333
Quickest round-trip
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Sun 11/1
10:19 am-1:20 pm
1 stop4h 01m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$343
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Sat 9/26
4:39 pm-10:42 pm
1 stop7h 03m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$363
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Sun 10/25
7:34 pm-11:59 pm
1 stop5h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$363
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Sat 9/19
7:33 am-1:03 pm
1 stop6h 30m
Lambert-St Louis
Wed 9/23
10:21 am-3:58 pm
1 stop4h 37m
$453
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Thu 10/22
5:13 pm-9:59 pm
1 stop5h 46m
Lambert-St Louis
Sun 10/25
6:07 pm-11:59 pm
1 stop4h 52m
$457
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Fri 10/9
5:13 pm-11:42 pm
1 stop7h 29m
Lambert-St Louis
Mon 10/12
6:07 pm-11:59 pm
1 stop4h 52m
$457
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Fri 10/2
4:39 pm-10:42 pm
1 stop7h 03m
Lambert-St Louis
Fri 10/9
6:07 pm-11:59 pm
1 stop4h 52m
$467
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Gainesville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Gainesville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Gainesville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Gainesville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.
GNV-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 8, 2026.
See what other customers who have flown with Delta from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
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Complete your trip
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Gainesville and St. Louis flights
Browse other Gainesville and St. Louis flight options. Last updated on September 8, 2026.
Other flights from Gainesville
Browse through other flights departing from Gainesville. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Top airline flying from Gainesville to St. Louis
Discover the top airline that operate flights from Gainesville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$372 | Average$485 | FlexibilityNo cancel fee | On-timeN/A |