What are the cheapest airlines flying from Gainesville to St. Louis round-trip?

Currently priced at $347, Delta will fly you from Gainesville to St. Louis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $352. Delta is 16% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Gainesville to St. Louis?

Travelers seeking maximum savings on their Gainesville to St. Louis flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What is the cheapest day to fly round-trip from Gainesville to St. Louis?

Friday is generally a great day to depart. Flying on this day could help you save up to 109%.

What is the cheapest month to fly from Gainesville to St. Louis?

August is one of the best times of the year to fly to St. Louis from Gainesville. Prices for August average $415 per person but you can even find prices for as low as $281. The most expensive prices can be found in the month of October. Opting for a August flight can save you 33% on your journey compared to booking in October

Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?

Yes. In addition to deals on Gainesville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Gainesville to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to St. Louis.

Can I find deals for business class flights from Gainesville to St. Louis?

Yes. Cheapflights offers flight deals from Gainesville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$169+ Flights from Gainesville to St. Louis

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Cheap flight deals from Gainesville to St. Louis

Round-trip from	$347 (Delta)
One-way from	$169 (Delta)
Popular in	October
Cheapest in	August
Average price	$408

From Gainesville Regional to Lambert-St Louis

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One-way flight from Gainesville Regional to Lambert-St Louis

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Highest demand for flights based on searches. 16% potential increase in price ($83 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Gainesville to St. Louis

Cheapest flights from Gainesville to St. Louis
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Tue 8/51:10 pmGNV - STL

1 stop6h 37mDelta

Thu 8/75:23 pmSTL - GNV

1 stop4h 23mDelta

Deal found 7/1

$347

Wed 10/293:02 pmGNV - STL

2 stops9h 37mAmerican Airlines

Sun 11/27:34 amSTL - GNV

1 stop4h 16mAmerican Airlines

Deal found 7/1

$352

Best flights from Gainesville to St. Louis
Discover carefully curated flight deals from Gainesville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Tue 8/51:10 pmGNV - STL

1 stop6h 37mDelta

Thu 8/75:23 pmSTL - GNV

1 stop4h 23mDelta

Deal found 7/1

$347

Wed 10/293:02 pmGNV - STL

2 stops9h 37mAmerican Airlines

Sun 11/27:34 amSTL - GNV

1 stop4h 16mAmerican Airlines

Deal found 7/1

$352

Last-minute flights from Gainesville to St. Louis
Discover last-minute flight deals from Gainesville to St. Louis. Data last updated July 3, 2025 and is based on user searches.

Thu 7/107:18 amGNV - STL

1 stop5h 38mAmerican Airlines

Wed 7/169:26 amSTL - GNV

1 stop5h 24mAmerican Airlines

Deal found 7/3

$450

Thu 7/101:10 pmGNV - STL

1 stop4h 08mDelta

Sun 7/135:23 pmSTL - GNV

1 stop4h 23mDelta

Deal found 7/2

$869

Tue 8/51:10 pmGNV - STL

1 stop6h 37mDelta

Thu 8/75:23 pmSTL - GNV

1 stop4h 23mDelta

Deal found 7/1

$347

One-way flights from Gainesville to St. Louis
Search for one-way flight options from Gainesville to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 3, 2025.

Wed 8/2710:17 amGNV - STL

1 stop6h 49mDelta

Deal found 7/1

$169

Wed 8/276:01 amGNV - STL

2 stops11h 13mAmerican Airlines

Deal found 7/1

$296

Cheapflights Fare Finder

Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Tue 8/5

1:10 pm-6:47 pm

1 stop6h 37m

Lambert-St Louis

Thu 8/7

5:23 pm-10:46 pm

1 stop4h 23m

$347

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Fri 9/19

10:25 am-6:23 pm

2 stops8h 58m

Lambert-St Louis

Sun 9/21

4:02 pm-10:26 pm

1 stop5h 24m

$436

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 8/27

10:17 am-4:06 pm

1 stop6h 49m

$169

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 8/27

6:01 am-4:14 pm

2 stops11h 13m

$296

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Gainesville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to St. Louis

What is the cheapest month to book a flight from Gainesville to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $311). Flying from Gainesville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to STL?

Unlike in the evening, when flights are generally more expensive, you can save up to 22% on flights from Gainesville to St. Louis by exploring options for tickets in the morning.

How much does it cost to fly round-trip from Gainesville to St. Louis?

Reviews of airlines servicing St. Louis

See what other customers who have flown with Delta and American Airlines from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What are the cheapest airlines flying from Gainesville to St. Louis round-trip?
Currently priced at $347, Delta will fly you from Gainesville to St. Louis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $352. Delta is 16% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?
Yes. In addition to deals on Gainesville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Gainesville to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to St. Louis.
Can I find deals for business class flights from Gainesville to St. Louis?
Yes. Cheapflights offers flight deals from Gainesville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Gainesville to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $311). Flying from Gainesville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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O'Fallon

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Collinsville

Eureka

St. Peters

Glencoe

Alton

Festus

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Top 2 airlines flying from Gainesville to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$208	Average$388	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$318	Average$420	FlexibilityNo cancel fee	On-time71%

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$169+ Cheap flights from Gainesville to St. Louis (GNV - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Gainesville to St. Louis with Cheapflights

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Cheap flight deals from Gainesville to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

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Find flight deals from Gainesville to St. Louis

Cheapest flights from Gainesville to St. LouisExplore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.

Best time to book a flight from Gainesville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to St. Louis

What is the cheapest month to book a flight from Gainesville to St. Louis?

What is the cheapest time of day to fly from GNV to STL?

Find hourly flight availability from Gainesville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

How much does it cost to fly round-trip from Gainesville to St. Louis?

Reviews of airlines servicing St. Louis

See what other customers who have flown with Delta and American Airlines from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Gainesville to St. Louis round-trip?

Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?

How can I find direct flights from Gainesville to St. Louis?

Can I find deals for business class flights from Gainesville to St. Louis?

What is the cheapest month to book a flight from Gainesville to St. Louis?

Traveling to a place near Gainesville?

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Alternative routes for Gainesville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Gainesville to St. Louis

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Cheapest flights from Gainesville to St. Louis
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.