$353+ Cheap flights from Gainesville to St. Louis (GNV - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — STL
Nov 29 — Dec 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Gainesville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Gainesville to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Gainesville to St. LouisExplore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:38 pm -
1 stop5h 04m
Sat 12/128:22 am -
1 stop6h 42m
Deal found 10/25![American Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:15 pm -
1 stop7h 18m
Sat 11/147:24 am -
1 stop8h 16m
Deal found 10/26![American Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:16 am -
1 stop4h 07m
Thu 12/312:36 pm -
1 stop4h 42m
Deal found 10/28![Delta logo]()
$507
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop6h 15m
Tue 11/177:13 am -
1 stop4h 33m
Deal found 10/28![Delta logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops11h 24m
Thu 12/35:04 am -
1 stop7h 10m
Deal found 10/28![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop5h 08m
Tue 11/178:29 am -
2 stops8h 37m
Deal found 10/28![American Airlines logo]()
$581
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:30 pm -
1 stop6h 27m
Thu 12/109:14 am -
1 stop7h 26m
Deal found 10/27![American Airlines logo]()
$591
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:18 am -
1 stop4h 10m
Sun 12/67:03 am -
1 stop4h 47m
Deal found 10/27![Delta logo]()
$607
Best flights from Gainesville to St. LouisDiscover carefully curated flight deals from Gainesville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Gainesville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:38 pm -
1 stop5h 04m
Sat 12/128:22 am -
1 stop6h 42m
Deal found 10/25![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:16 am -
1 stop4h 07m
Thu 12/312:36 pm -
1 stop4h 42m
Deal found 10/28![Delta logo]()
$507
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:15 pm -
1 stop7h 18m
Sat 11/147:24 am -
1 stop8h 16m
Deal found 10/26![American Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop6h 15m
Tue 11/177:13 am -
1 stop4h 33m
Deal found 10/28![Delta logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
1 stop7h 08m
Thu 12/32:54 pm -
1 stop6h 59m
Deal found 10/28![American Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:18 am -
1 stop4h 10m
Sun 12/67:03 am -
1 stop4h 47m
Deal found 10/27![Delta logo]()
$607
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:44 pm -
2 stops10h 15m
Thu 12/106:47 am -
1 stop7h 00m
Deal found 10/27![American Airlines logo]()
$621
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:59 pm -
1 stop5h 56m
Mon 12/287:15 pm -
1 stop3h 44m
Deal found 10/28![Delta logo]()
$639
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:27 pm -
1 stop4h 29m
Sun 11/86:00 am -
1 stop5h 48m
Deal found 10/27![Delta logo]()
$645
Last-minute flights from Gainesville to St. LouisDiscover last-minute flight deals from Gainesville to St. Louis. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to St. Louis. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am -
1 stop6h 54m
Fri 11/62:54 pm -
2 stops8h 05m
Deal found 10/30![American Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:30 pm -
1 stop6h 27m
Thu 12/109:14 am -
1 stop7h 26m
Deal found 10/27![American Airlines logo]()
$591
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:27 pm -
1 stop4h 29m
Sun 11/86:00 am -
1 stop5h 48m
Deal found 10/27![Delta logo]()
$645
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:15 pm -
1 stop7h 18m
Sat 11/147:24 am -
1 stop8h 16m
Deal found 10/26![American Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop6h 15m
Tue 11/177:13 am -
1 stop4h 33m
Deal found 10/28![Delta logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop5h 08m
Tue 11/178:29 am -
2 stops8h 37m
Deal found 10/28![American Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:16 am -
1 stop4h 07m
Thu 12/312:36 pm -
1 stop4h 42m
Deal found 10/28![Delta logo]()
$507
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops11h 24m
Thu 12/35:04 am -
1 stop7h 10m
Deal found 10/28![American Airlines logo]()
$555
One-way flights from Gainesville to St. LouisSearch for one-way flight options from Gainesville to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Gainesville to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop6h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:38 pm -
2 stops7h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$385
Find flight deals from Gainesville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $493 (American Airlines) |
One-way from | $353 (Delta) |
Popular in | April |
Cheapest in | November |
Average price | $434 |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Tue 12/1
10:18 am-1:28 pm
1 stop4h 10m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$353
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Tue 12/1
1:38 pm-7:50 pm
2 stops7h 12m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$385
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Sat 12/5
6:38 pm-10:42 pm
1 stop5h 04m
Lambert-St Louis
Sat 12/12
8:22 am-4:04 pm
1 stop6h 42m
$423
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Tue 11/10
5:15 pm-11:33 pm
1 stop7h 18m
Lambert-St Louis
Sat 11/14
7:24 am-4:40 pm
1 stop8h 16m
$493
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Thu 11/26
10:16 am-1:23 pm
1 stop4h 07m
Lambert-St Louis
Thu 12/3
12:36 pm-6:18 pm
1 stop4h 42m
$507
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Thu 11/26
6:10 am-12:18 pm
1 stop7h 08m
Lambert-St Louis
Thu 12/3
2:54 pm-10:53 pm
1 stop6h 59m
$507
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Fri 11/13
6:00 am-11:15 am
1 stop6h 15m
Lambert-St Louis
Tue 11/17
7:13 am-12:46 pm
1 stop4h 33m
$546
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Fri 12/4
10:18 am-1:28 pm
1 stop4h 10m
Lambert-St Louis
Sun 12/6
7:03 am-12:50 pm
1 stop4h 47m
$607
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Mon 11/2
2:44 pm-11:59 pm
2 stops10h 15m
Lambert-St Louis
Thu 12/10
6:47 am-2:47 pm
1 stop7h 00m
$621
GainesvilleSt. Louis
GNV Gainesville Regional - STL Lambert-St Louis
GNVSTL
Gainesville Regional
Wed 12/23
6:59 pm-11:55 pm
1 stop5h 56m
Lambert-St Louis
Mon 12/28
7:15 pm-11:59 pm
1 stop3h 44m
$639
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Gainesville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Gainesville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Gainesville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Gainesville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.
GNV-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 30, 2026.
See what other customers who have flown with Delta from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Gainesville
Popular flights
St. Louis flight routes
Alternative routes for Gainesville to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Gainesville to St. Louis by cabin class
Find flights from Gainesville to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Gainesville and St. Louis flights
Browse other Gainesville and St. Louis flight options. Last updated on October 30, 2026.
Other flights from Gainesville
Browse through other flights departing from Gainesville. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Top airline flying from Gainesville to St. Louis
Discover the top airline that operate flights from Gainesville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$372 | Average$485 | FlexibilityNo cancel fee | On-timeN/A |