$219+ Cheap flights from the United States to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Oct 22 — Oct 291
Round-trip
1 adult, Economy
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Find cheap flights from USA to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from USA to PanamaExplore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:54 pm -
Nonstop3h 07m
Sun 11/159:31 pm -
Nonstop3h 06m
Deal found 9/17![Copa Airlines logo]()
$497
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:41 am -
Nonstop3h 08m
Tue 12/110:25 am -
Nonstop3h 10m
Deal found 9/17![Copa Airlines logo]()
$498
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:36 am -
Nonstop3h 08m
Mon 11/306:15 pm -
Nonstop3h 06m
Deal found 9/22![Copa Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:01 am -
Nonstop3h 12m
Sun 12/133:13 pm -
Nonstop3h 10m
Deal found 9/17![American Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:45 am -
1 stop8h 27m
Tue 2/234:41 pm -
1 stop22h 44m
Deal found 9/22![United Airlines logo]()
$508
This Bravofly deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:19 pm -
Nonstop3h 10m
Thu 1/79:48 pm -
Nonstop3h 07m
Deal found 9/20![Copa Airlines logo]()
$516
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:24 am -
1 stop13h 14m
Tue 11/178:55 am -
1 stop11h 00m
Deal found 9/22![United Airlines logo]()
$517
This Avianca deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:35 am -
1 stop7h 35m
Sun 11/155:30 am -
2 stops7h 45m
Deal found 9/22![Avianca logo]()
$521
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:15 am -
1 stop9h 45m
Sat 10/315:30 am -
1 stop5h 45m
Deal found 9/17![Avianca logo]()
$522
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:00 pm -
1 stop9h 20m
Thu 11/125:30 am -
2 stops7h 45m
Deal found 9/21![Avianca logo]()
$523
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:00 pm -
1 stop11h 35m
Tue 10/65:30 am -
1 stop5h 40m
Deal found 9/17![Avianca logo]()
$524
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:25 am -
Nonstop4h 48m
Sat 10/246:41 pm -
Nonstop4h 51m
Deal found 9/22![Copa Airlines logo]()
$524
Best flights from USA to PanamaDiscover carefully curated flight deals from USA to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from USA to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:02 am -
Nonstop3h 06m
Mon 11/2312:33 pm -
Nonstop3h 06m
Deal found 9/17![Copa Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:35 am -
1 stop13h 03m
Wed 12/28:55 am -
1 stop9h 20m
Deal found 9/21![United Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:44 pm -
1 stop17h 19m
Tue 12/153:29 pm -
1 stop12h 26m
Deal found 9/17![Delta logo]()
$549
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:00 pm -
1 stop9h 20m
Tue 11/172:30 am -
1 stop11h 55m
Deal found 9/17![Avianca logo]()
$572
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:41 am -
Nonstop3h 08m
Thu 11/199:48 pm -
Nonstop3h 14m
Deal found 9/17![Copa Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:24 am -
1 stop8h 21m
Thu 11/198:55 am -
1 stop13h 04m
Deal found 9/17![United Airlines logo]()
$517
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:34 pm -
Nonstop3h 11m
Sun 11/299:31 pm -
Nonstop3h 06m
Deal found 9/21![Copa Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop7h 59m
Wed 10/212:24 pm -
1 stop17h 55m
Deal found 9/17![Delta logo]()
$575
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:45 am -
1 stop10h 53m
Sun 12/208:55 am -
1 stop18h 20m
Deal found 9/19![United Airlines logo]()
$549
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:54 pm -
Nonstop3h 07m
Mon 11/309:31 pm -
Nonstop3h 07m
Deal found 9/20![Copa Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:15 am -
1 stop8h 23m
Wed 11/184:41 pm -
1 stop18h 14m
Deal found 9/18![United Airlines logo]()
$549
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:41 am -
Nonstop3h 08m
Sun 11/86:30 pm -
Nonstop3h 06m
Deal found 9/17![Copa Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:52 am -
Nonstop4h 10m
Thu 11/193:29 pm -
Nonstop4h 17m
Deal found 9/17![Delta logo]()
$616
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:59 pm -
1 stop16h 39m
Tue 12/14:41 pm -
1 stop10h 03m
Deal found 9/19![United Airlines logo]()
$549
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:34 pm -
Nonstop3h 11m
Tue 12/14:00 pm -
Nonstop3h 07m
Deal found 9/17![Copa Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop7h 59m
Sat 10/242:24 pm -
1 stop9h 18m
Deal found 9/21![Delta logo]()
$632
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:45 am -
1 stop10h 53m
Thu 11/198:55 am -
1 stop13h 04m
Deal found 9/21![United Airlines logo]()
$550
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:33 am -
Nonstop3h 02m
Mon 12/289:31 pm -
Nonstop3h 07m
Deal found 9/21![Copa Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:48 pm -
1 stop21h 11m
Wed 10/212:24 pm -
1 stop9h 18m
Deal found 9/17![Delta logo]()
$642
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:24 am -
1 stop8h 21m
Tue 11/178:55 am -
1 stop11h 00m
Deal found 9/21![United Airlines logo]()
$550
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:48 pm -
1 stop21h 11m
Thu 10/222:24 pm -
1 stop9h 18m
Deal found 9/17![Delta logo]()
$642
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:41 am -
Nonstop5h 52m
Tue 11/174:18 pm -
Nonstop5h 43m
Deal found 9/18![Copa Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:33 pm -
2 stops20h 39m
Wed 12/98:55 am -
1 stop14h 28m
Deal found 9/19![United Airlines logo]()
$553
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/412:40 am -
Nonstop6h 25m
Sat 2/136:33 pm -
Nonstop7h 03m
Deal found 9/17![Copa Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:42 pm -
3 stops23h 03m
Sat 12/1211:35 am -
2 stops22h 44m
Deal found 9/17![United Airlines logo]()
$553
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:41 am -
Nonstop3h 08m
Sun 11/159:31 pm -
Nonstop3h 06m
Deal found 9/20![Copa Airlines logo]()
$535
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:40 am -
2 stops14h 51m
Tue 10/273:41 pm -
2 stops20h 52m
Deal found 9/21![United Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:05 am -
1 stop12h 32m
Sun 10/253:41 pm -
2 stops19h 33m
Deal found 9/18![United Airlines logo]()
$579
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:16 pm -
Nonstop4h 15m
Mon 10/1910:00 am -
Nonstop4h 24m
Deal found 9/21![Copa Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:40 am -
2 stops14h 51m
Mon 10/263:41 pm -
1 stop17h 55m
Deal found 9/17![United Airlines logo]()
$579
Last-minute flights from USA to PanamaDiscover last-minute flight deals from USA to Panama. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from USA to Panama. Data last updated September 22, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:00 pm -
1 stop11h 35m
Tue 10/65:30 am -
1 stop5h 40m
Deal found 9/17![Avianca logo]()
$524
This Trip.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:15 am -
1 stop9h 45m
Mon 10/124:25 am -
1 stop18h 05m
Deal found 9/17![Avianca logo]()
$536
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:34 pm -
Nonstop5h 01m
Sun 10/119:13 am -
Nonstop4h 51m
Deal found 9/22![Copa Airlines logo]()
$544
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:50 pm -
1 stop11h 05m
Wed 10/214:25 am -
1 stop7h 00m
Deal found 9/21![Avianca logo]()
$526
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:50 pm -
1 stop11h 05m
Mon 10/194:25 am -
1 stop12h 40m
Deal found 9/19![Avianca logo]()
$523
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:50 pm -
1 stop11h 05m
Fri 10/163:10 pm -
1 stop7h 20m
Deal found 9/17![Avianca logo]()
$525
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:25 am -
Nonstop4h 48m
Sat 10/246:41 pm -
Nonstop4h 51m
Deal found 9/22![Copa Airlines logo]()
$524
This Booking.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:16 pm -
Nonstop4h 15m
Mon 10/2610:00 am -
Nonstop4h 24m
Deal found 9/21![Copa Airlines logo]()
$556
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:52 am -
Nonstop4h 07m
Fri 10/232:24 pm -
Nonstop4h 15m
Deal found 9/22![Delta logo]()
$560
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:15 am -
1 stop9h 45m
Sat 10/315:30 am -
1 stop5h 45m
Deal found 9/17![Avianca logo]()
$522
This Super.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:20 pm -
1 stop19h 50m
Sat 11/284:10 pm -
1 stop7h 55m
Deal found 9/22![Avianca logo]()
$530
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:14 pm -
Nonstop3h 06m
Fri 11/136:15 pm -
Nonstop3h 06m
Deal found 9/21![Copa Airlines logo]()
$535
One-way flights from USA to PanamaSearch for one-way flight options from USA to Panama. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from USA to Panama. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Booking.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:54 pm -
Nonstop3h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Copa Airlines logo]()
$219
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:54 pm -
Nonstop3h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Copa Airlines logo]()
$221
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:45 am -
1 stop10h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:41 am -
Nonstop3h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Copa Airlines logo]()
$230
This Booking.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:05 am -
Nonstop6h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$232
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:01 am -
Nonstop3h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![American Airlines logo]()
$235
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:19 pm -
Nonstop3h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Copa Airlines logo]()
$236
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:43 pm -
Nonstop5h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Copa Airlines logo]()
$237
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:30 am -
Nonstop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$237
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:45 am -
1 stop10h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:36 am -
Nonstop3h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:44 pm -
Nonstop3h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Copa Airlines logo]()
$240
Find flight deals from USA to Panama
Keep the following information in mind while searching for USA to Panama flight deals. Data was last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $497 (Booking.com) |
One-way from | $219 (Booking.com) |
Popular in | December |
Cheapest in | March |
Average price | $744 |
Good round-trip deal | $422 or less |
Good one-way deal | $199 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from the United States to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Sat 12/12
4:42 am-7:49 am
Nonstop3h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$221
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Tue 12/15
12:44 pm-4:01 pm
Nonstop3h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$221
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Sat 11/21
5:22 pm-8:29 pm
Nonstop3h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$221
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Wed 11/25
8:45 am-7:38 pm
1 stop10h 53m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$226
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Sun 11/22
6:24 am-2:45 pm
1 stop8h 21m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$226
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Tue 12/1
10:06 am-7:38 pm
1 stop9h 32m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$226
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Tue 11/17
8:45 am-7:38 pm
1 stop10h 53m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$226
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Wed 12/16
12:44 pm-4:01 pm
Nonstop3h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$236
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Mon 11/30
4:42 am-7:49 am
Nonstop3h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$236
MiamiPanama City
MIA Miami - PTY Panama City Tocumen Intl
MIAPTY
Miami
Tue 12/8
5:37 am-8:44 am
Nonstop3h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$236
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from USA with our price prediction graph.
MIA-PTY
LAX-PTY
MCO-PTY
SFO-PTY
ATL-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to Panama
US0-PA0
MIA-PTY
LAX-PTY
MCO-PTY
SFO-PTY
What is the cheapest month to book a flight from USA to Panama?
Currently, April is the cheapest month in which you can book a flight from USA to Panama (average of $596). Flying from USA to Panama in December is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to PA?
Find hourly flight availability from USA to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2026.
A simple way to save on the total cost of your ticket is to fly from USA to Panama at noon. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the afternoon.
Weekly flight availability from USA to Panama
Explore weekly flight availability from USA to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 22, 2026.
The most flights from US0 to PA0 are scheduled on a Monday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (8 on average).
How often are flights from the United States to Panama delayed?
About 12% of weekly flights between United States and Panama have experienced delays in the past year, with the average delay time being 127 minutes.
What is the most punctual flight time for the United States to Panama flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on the United States to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 8% of flights being delayed.
How far ahead should I book a flight from USA to Panama?
To ensure you get the cheapest price possible for a flight from USA to Panama, you should look to book at least 55 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from USA to Panama?
Use this chart to determine the cheapest time to fly round-trip from USA to Panama. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their USA to Panama flight should consider departing on Saturday afternoons when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 22, 2026.
Read through reviews of airlines operating flights from the United States to Panama, such as Delta,Copa Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from USA to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for USA to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to Panama by cabin class
Find flights from USA to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and Panama flights
Browse other USA and Panama flight options. Last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Panama
Find the right flight back to USA after your stay in Panama
USA to Panama flights
Consider these flights traveling from USA to Panama.
Top 7 airlines flying from USA to Panama
Discover the top 7 airlines that operate flights from USA to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$214 | Average$666 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$218 | Average$509 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$226 | Average$670 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$317 | Average$722 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$327 | Average$693 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$391 | Average$587 | FlexibilityNo cancel fee | On-time74% | |
| Cheapest$515 | Average$613 | FlexibilityNo cancel fee | On-time62% |