$208+ Cheap flights from the United States to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Sep 4 — Sep 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from USA to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from USA to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from USA to PanamaExplore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
Explore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:22 pm -
Nonstop3h 07m
Sun 11/229:31 pm -
Nonstop3h 06m
Deal found 8/3![Copa Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:36 am -
Nonstop3h 08m
Sun 11/296:15 pm -
Nonstop3h 06m
Deal found 7/31![Copa Airlines logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:36 am -
Nonstop3h 08m
Sun 11/296:15 pm -
Nonstop3h 06m
Deal found 7/31![Copa Airlines logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:21 am -
Nonstop3h 09m
Thu 9/2410:10 am -
2 stops18h 39m
Deal found 8/3![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:25 pm -
Nonstop3h 05m
Tue 9/2912:21 pm -
1 stop16h 28m
Deal found 7/31![Multiple Airlines logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:31 pm -
Nonstop3h 06m
Wed 10/1410:10 am -
2 stops21h 40m
Deal found 8/3![Multiple Airlines logo]()
$450
This Booking.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:31 pm -
Nonstop3h 06m
Tue 9/226:34 pm -
Nonstop3h 14m
Deal found 8/1![Copa Airlines logo]()
$454
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:45 am -
1 stop12h 30m
Fri 9/255:30 am -
1 stop5h 40m
Deal found 7/31![Avianca logo]()
$456
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 pm -
2 stops8h 55m
Tue 9/15:30 am -
2 stops7h 30m
Deal found 7/31![Avianca logo]()
$458
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 pm -
2 stops8h 55m
Mon 9/75:30 am -
1 stop5h 40m
Deal found 7/31![Avianca logo]()
$459
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:45 am -
1 stop7h 30m
Wed 9/25:30 am -
2 stops7h 30m
Deal found 8/3![Avianca logo]()
$460
This Booking.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:13 pm -
Nonstop3h 06m
Sun 9/2712:03 pm -
Nonstop3h 12m
Deal found 8/3![Copa Airlines logo]()
$495
Best flights from USA to PanamaDiscover carefully curated flight deals from USA to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
Discover carefully curated flight deals from USA to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:05 pm -
1 stop8h 30m
Wed 10/145:30 am -
2 stops7h 30m
Deal found 8/3![Avianca logo]()
$464
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:14 pm -
Nonstop3h 06m
Sun 10/49:33 pm -
Nonstop3h 14m
Deal found 8/2![Copa Airlines logo]()
$482
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:41 am -
1 stop12h 57m
Thu 1/2811:35 am -
1 stop8h 24m
Deal found 8/1![United Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:59 pm -
1 stop16h 59m
Mon 9/282:23 pm -
1 stop9h 34m
Deal found 8/2![Delta logo]()
$591
This Avianca deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:05 am -
1 stop6h 45m
Mon 11/302:55 pm -
1 stop12h 15m
Deal found 8/2![Avianca logo]()
$464
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:57 am -
Nonstop3h 09m
Thu 10/229:33 pm -
Nonstop3h 14m
Deal found 8/1![Copa Airlines logo]()
$482
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:05 pm -
1 stop30h 32m
Thu 10/2210:00 am -
1 stop9h 13m
Deal found 8/1![United Airlines logo]()
$507
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:45 am -
1 stop7h 30m
Sun 9/205:30 am -
2 stops7h 30m
Deal found 7/31![Avianca logo]()
$465
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:13 pm -
Nonstop3h 06m
Tue 9/812:03 pm -
Nonstop3h 12m
Deal found 7/31![Copa Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop8h 45m
Wed 10/283:41 pm -
1 stop18h 47m
Deal found 8/4![United Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am -
1 stop7h 28m
Tue 9/292:23 pm -
1 stop9h 34m
Deal found 8/1![Delta logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:13 pm -
Nonstop3h 06m
Tue 9/812:03 pm -
Nonstop3h 12m
Deal found 8/4![Copa Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 am -
1 stop7h 29m
Tue 10/202:24 pm -
1 stop9h 58m
Deal found 8/4![Delta logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:12 pm -
Nonstop3h 07m
Thu 9/312:03 pm -
Nonstop3h 12m
Deal found 7/31![Copa Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:10 am -
1 stop13h 52m
Sat 11/78:55 am -
1 stop13h 49m
Deal found 8/2![United Airlines logo]()
$559
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:13 pm -
Nonstop3h 06m
Sun 9/1312:03 pm -
Nonstop3h 12m
Deal found 8/2![Copa Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:51 am -
Nonstop4h 07m
Wed 9/302:23 pm -
Nonstop4h 13m
Deal found 8/3![Delta logo]()
$616
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:45 am -
1 stop13h 46m
Mon 10/267:55 am -
1 stop15h 42m
Deal found 7/31![United Airlines logo]()
$590
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:13 pm -
Nonstop3h 06m
Sun 9/2012:03 pm -
Nonstop3h 12m
Deal found 8/3![Copa Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:51 am -
Nonstop4h 07m
Tue 10/62:24 pm -
Nonstop4h 15m
Deal found 8/2![Delta logo]()
$616
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:00 am -
1 stop8h 37m
Sun 9/2710:00 am -
1 stop11h 30m
Deal found 7/31![United Airlines logo]()
$590
This Copa Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:31 pm -
Nonstop3h 06m
Thu 10/810:25 am -
Nonstop3h 14m
Deal found 8/4![Copa Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:00 am -
1 stop6h 45m
Wed 1/278:55 am -
1 stop8h 08m
Deal found 8/4![United Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:24 am -
Nonstop3h 06m
Sun 9/69:33 pm -
Nonstop3h 14m
Deal found 7/31![Copa Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop7h 59m
Fri 4/302:25 pm -
1 stop8h 16m
Deal found 8/1![Delta logo]()
$701
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:15 am -
1 stop8h 59m
Tue 10/2010:00 am -
1 stop10h 00m
Deal found 8/3![United Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:01 am -
Nonstop3h 09m
Sun 9/136:34 pm -
Nonstop3h 14m
Deal found 8/4![Copa Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop7h 59m
Sun 11/83:24 pm -
1 stop8h 16m
Deal found 8/3![Delta logo]()
$701
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:57 am -
1 stop6h 40m
Mon 10/267:55 am -
1 stop11h 45m
Deal found 8/4![United Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:14 pm -
Nonstop3h 06m
Wed 9/96:15 pm -
Nonstop3h 14m
Deal found 8/1![Copa Airlines logo]()
$496
Last-minute flights from USA to PanamaDiscover last-minute flight deals from USA to Panama. Data last updated August 5, 2026 and is based on user searches.
Discover last-minute flight deals from USA to Panama. Data last updated August 5, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:15 am -
1 stop7h 00m
Sun 8/305:30 am -
2 stops7h 30m
Deal found 8/5![Avianca logo]()
$463
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 pm -
2 stops8h 55m
Tue 9/15:30 am -
2 stops7h 30m
Deal found 7/31![Avianca logo]()
$458
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:15 am -
1 stop7h 00m
Fri 8/2810:10 am -
1 stop6h 55m
Deal found 7/31![Avianca logo]()
$462
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:45 am -
1 stop7h 30m
Wed 9/25:30 am -
2 stops7h 30m
Deal found 8/3![Avianca logo]()
$460
This Avianca deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:15 am -
1 stop9h 45m
Tue 9/85:30 am -
2 stops7h 30m
Deal found 8/4![Avianca logo]()
$461
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 pm -
2 stops8h 55m
Mon 9/75:30 am -
1 stop5h 40m
Deal found 7/31![Avianca logo]()
$459
This Booking.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:31 pm -
Nonstop3h 06m
Tue 9/226:34 pm -
Nonstop3h 14m
Deal found 8/1![Copa Airlines logo]()
$454
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:45 am -
1 stop12h 30m
Fri 9/255:30 am -
1 stop5h 40m
Deal found 7/31![Avianca logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:21 am -
Nonstop3h 09m
Thu 9/2410:10 am -
2 stops18h 39m
Deal found 8/3![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:31 pm -
Nonstop3h 06m
Wed 10/1410:10 am -
2 stops21h 40m
Deal found 8/3![Multiple Airlines logo]()
$450
This Booking.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:13 pm -
Nonstop3h 06m
Sun 9/2712:03 pm -
Nonstop3h 12m
Deal found 8/3![Copa Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:25 pm -
Nonstop3h 05m
Tue 9/2912:21 pm -
1 stop16h 28m
Deal found 7/31![Multiple Airlines logo]()
$449
One-way flights from USA to PanamaSearch for one-way flight options from USA to Panama. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
Search for one-way flight options from USA to Panama. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
This Booking.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:14 pm -
Nonstop3h 06m
Deal found 8/1![Copa Airlines logo]()
$208
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:21 am -
Nonstop3h 09m
Deal found 7/31![Copa Airlines logo]()
$211
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
1 stop8h 14m
Deal found 8/1![United Airlines logo]()
$216
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:45 am -
1 stop10h 52m
Deal found 8/3![United Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:31 pm -
Nonstop3h 06m
Deal found 7/31![Copa Airlines logo]()
$219
This Copa Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:01 am -
Nonstop3h 09m
Deal found 8/4![Copa Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:21 am -
Nonstop3h 09m
Deal found 8/2![Copa Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:23 pm -
Nonstop3h 06m
Deal found 8/4![Copa Airlines logo]()
$230
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:00 am -
1 stop29h 45m
Deal found 8/4![United Airlines logo]()
$231
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:00 pm -
1 stop26h 37m
Deal found 8/3![United Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:14 pm -
Nonstop3h 06m
Deal found 8/4![Copa Airlines logo]()
$232
This Mytrip deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:59 am -
2 stops32h 16m
Deal found 8/2![Multiple Airlines logo]()
$253
Find flight deals from USA to Panama
Keep the following information in mind while searching for USA to Panama flight deals. Data was last updated August 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $429 (Kiwi.com) |
One-way from | $208 (Booking.com) |
Popular in | December |
Cheapest in | March |
Average price | $694 |
Good round-trip deal | $387 or less |
Good one-way deal | $144 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
Use the filters below to find and compare flights from the United States to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MiamiPanama City
MIA - PTY
MIAPTY
Miami
Tue 9/22
5:05 pm-12:35 am
1 stop8h 30m
Panama City Tocumen Intl
Wed 10/14
5:30 am-2:00 pm
2 stops7h 30m
$464
MiamiPanama City
MIA - PTY
MIAPTY
Miami
Sun 11/1
2:05 am-8:50 am
1 stop6h 45m
Panama City Tocumen Intl
Mon 11/30
2:55 pm-3:10 am
1 stop12h 15m
$464
MiamiPanama City
MIA - PTY
MIAPTY
Miami
Fri 9/18
2:45 am-9:15 am
1 stop7h 30m
Panama City Tocumen Intl
Sun 9/20
5:30 am-2:00 pm
2 stops7h 30m
$465
MiamiPanama City
MIA - PTY
MIAPTY
Miami
Fri 10/2
5:14 pm-7:20 pm
Nonstop3h 06m
Panama City Tocumen Intl
Sun 10/4
9:33 pm-1:47 am
Nonstop3h 14m
$482
MiamiPanama City
MIA - PTY
MIAPTY
Miami
Fri 10/9
5:57 am-8:06 am
Nonstop3h 09m
Panama City Tocumen Intl
Thu 10/22
9:33 pm-1:47 am
Nonstop3h 14m
$482
Quickest round-trip
Fort LauderdalePanama City
FLL - PTY
FLLPTY
Fort Lauderdale
Thu 9/3
6:13 pm-8:19 pm
Nonstop3h 06m
Panama City Tocumen Intl
Tue 9/8
12:03 pm-4:15 pm
Nonstop3h 12m
$496
Fort LauderdalePanama City
FLL - PTY
FLLPTY
Fort Lauderdale
Wed 9/2
6:13 pm-8:19 pm
Nonstop3h 06m
Panama City Tocumen Intl
Tue 9/8
12:03 pm-4:15 pm
Nonstop3h 12m
$496
Fort LauderdalePanama City
FLL - PTY
FLLPTY
Fort Lauderdale
Thu 8/27
6:12 pm-8:19 pm
Nonstop3h 07m
Panama City Tocumen Intl
Thu 9/3
12:03 pm-4:15 pm
Nonstop3h 12m
$496
Fort LauderdalePanama City
FLL - PTY
FLLPTY
Fort Lauderdale
Wed 9/9
6:13 pm-8:19 pm
Nonstop3h 06m
Panama City Tocumen Intl
Sun 9/13
12:03 pm-4:15 pm
Nonstop3h 12m
$496
Fort LauderdalePanama City
FLL - PTY
FLLPTY
Fort Lauderdale
Thu 9/17
6:13 pm-8:19 pm
Nonstop3h 06m
Panama City Tocumen Intl
Sun 9/20
12:03 pm-4:15 pm
Nonstop3h 12m
$496
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from USA with our price prediction graph.
MIA-PTY
FLL-PTY
DFW-PTY
IAD-PTY
ATL-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to Panama
US0-PA0
MIA-PTY
FLL-PTY
DFW-PTY
IAD-PTY
What is the cheapest month to book a flight from USA to Panama?
Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $564). Flying from USA to Panama in December is currently the most expensive (average of $720). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to PA?
Find hourly flight availability from USA to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 5, 2026.
A simple way to save on the total cost of your ticket is to fly from USA to Panama at noon. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.
Weekly flight availability from USA to Panama
Explore weekly flight availability from USA to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 5, 2026.
The most flights from US0 to PA0 are scheduled on a Monday (9 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (5 on average).
How often are flights from the United States to Panama delayed?
About 12% of weekly flights between United States and Panama have experienced delays in the past year, with the average delay time being 126 minutes.
What is the most punctual flight time for the United States to Panama flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Friday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on the United States to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 8% of flights being delayed.
How far ahead should I book a flight from USA to Panama?
To ensure you get the cheapest price possible for a flight from USA to Panama, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from USA to Panama?
Use this chart to determine the cheapest time to fly round-trip from USA to Panama. Price data was last updated on August 1, 2026.
Travelers seeking maximum savings on their USA to Panama flight should consider departing on Saturday afternoons when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 5, 2026.
Read through reviews of airlines operating flights from the United States to Panama, such as Delta,Copa Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from USA to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for USA to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to Panama by cabin class
Find flights from USA to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and Panama flights
Browse other USA and Panama flight options. Last updated on August 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Panama
Find the right flight back to USA after your stay in Panama
USA to Panama flights
Consider these flights traveling from USA to Panama.
Top 7 airlines flying from USA to Panama
Discover the top 7 airlines that operate flights from USA to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$496 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$237 | Average$657 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$247 | Average$683 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$706 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$300 | Average$705 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$391 | Average$550 | FlexibilityNo cancel fee | On-time74% | |
| Cheapest$515 | Average$631 | FlexibilityNo cancel fee | On-time62% |