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Panama City

$269+ Cheap flights from Greenville (GSP) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — PTY
Aug 25 — Sep 11
Tue 8/25
Tue 9/1
1 adult, Economy
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Cheap flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.

This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:00 am
GSP
-
PTY
1 stop6h 58m
Delta
Wed 9/302:23 pm
PTY
-
GSP
1 stop7h 32m
Delta
Deal found 7/21$587
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:20 am
GSP
-
PTY
2 stops14h 11m
United Airlines
Wed 9/309:45 am
PTY
-
GSP
1 stop12h 28m
United Airlines
Deal found 7/21$591
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:17 am
GSP
-
PTY
1 stop6h 38m
Delta
Mon 9/142:23 pm
PTY
-
GSP
1 stop7h 32m
Delta
Deal found 7/24$595
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am
GSP
-
PTY
1 stop13h 31m
United Airlines
Thu 10/153:30 pm
PTY
-
GSP
1 stop29h 28m
United Airlines
Deal found 7/25$597
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:20 am
GSP
-
PTY
2 stops14h 11m
United Airlines
Wed 9/1610:00 am
PTY
-
GSP
1 stop10h 58m
United Airlines
Deal found 7/25$599
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:25 am
GSP
-
PTY
1 stop17h 39m
United Airlines
Thu 9/39:45 am
PTY
-
GSP
1 stop12h 18m
United Airlines
Deal found 7/23$603
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:50 am
GSP
-
PTY
1 stop7h 55m
United Airlines
Tue 11/310:00 am
PTY
-
GSP
1 stop13h 37m
United Airlines
Deal found 7/21$613
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 pm
GSP
-
PTY
1 stop18h 59m
American Airlines
Wed 9/21:39 pm
PTY
-
GSP
2 stops19h 49m
American Airlines
Deal found 7/23$619
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:30 am
GSP
-
PTY
2 stops14h 01m
United Airlines
Sat 9/53:30 pm
PTY
-
GSP
2 stops21h 02m
United Airlines
Deal found 7/23$625

Find flight deals from Greenville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$587
(Delta)

One-way from

$269
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$695
Provider with most accurate pricing for Greenville-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Panama City Tocumen Intl flights.
Search Deals
From Greenville to Panama City Tocumen Intl
Search Deals
One-way flight from Greenville to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($160 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($65 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 9/23

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Wed 9/30

9:45 am-11:13 pm

1 stop12h 28m

$587

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 9/23

7:00 am-12:58 pm

1 stop6h 58m

Panama City Tocumen Intl

Wed 9/30

2:23 pm-10:55 pm

1 stop7h 32m

$587

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 9/15

6:30 am-7:31 pm

2 stops14h 01m

Panama City Tocumen Intl

Thu 10/15

9:45 am-11:13 pm

1 stop12h 28m

$591
Quickest round-trip

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 9/7

7:17 am-12:55 pm

1 stop6h 38m

Panama City Tocumen Intl

Mon 9/14

2:23 pm-10:55 pm

1 stop7h 32m

$595

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 9/9

6:20 am-7:31 pm

2 stops14h 11m

Panama City Tocumen Intl

Wed 9/16

10:00 am-9:58 pm

1 stop10h 58m

$599

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 9/7

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Mon 9/14

9:45 am-9:35 am

2 stops22h 50m

$599

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 1/5

5:00 am-1:53 pm

1 stop8h 53m

Panama City Tocumen Intl

Fri 2/5

2:27 pm-11:57 pm

1 stop9h 30m

$603

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 8/19

5:46 am-12:55 pm

1 stop8h 09m

Panama City Tocumen Intl

Wed 8/26

2:20 pm-10:59 pm

1 stop7h 39m

$603
Cheapest one-way

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 8/26

10:33 am-4:04 am

2 stops18h 31m

$269
Quickest one-way

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 8/26

6:55 am-12:55 pm

1 stop7h 00m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/21

Sorted by cheapest first

Compare providers for flights from Greenville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Panama City in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City?

Currently, September is the cheapest month in which you can book a flight from Greenville to Panama City (average of $235). Flying from Greenville to Panama City in December is currently the most expensive (average of $1,387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Panama City?

Airfare is below average for this route at the moment.

Greenville to Panama City flights typically cost between $614 and $678 in September.
The cheapest round-trip price found within the last 5 days was $587 on Delta (Sep 23-Sep 30).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 26, 2026.
Read reviews from past customers who have flown American Airlines from Greenville to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,851 reviews

Crew

7.9

Food

6.4

Overall

7.1

Entertainment

6.8

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.1
Good
11,851 reviews
American Airlines
7.1
Good
11,851 reviews

Crew

7.9

Food

6.4

Overall

7.1

Entertainment

6.8

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Panama City?

    United Airlines and Delta can get you from Greenville to Panama City in just under 6h 58m. Your travel time can differ by up to 6h 33m. Greenville and Panama City are separated by a distance of 1792 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Greenville to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $495. American Airlines is priced at 27% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Panama City that include hotel bookings?

    Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.

  • Can I find deals for business class flights from Greenville to Panama City?

    Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Greenville to Panama City (average of $235). Flying from Greenville to Panama City in December is currently the most expensive (average of $1,387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Greenville to Panama City

Discover the top airline that operate flights from Greenville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$495Average$664FlexibilityNo cancel feeOn-time71%

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