What are the cheapest airlines flying from Charleston to Panama City round-trip?

Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $327. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $369 and $378, respectively. These flights start at 35% lower than the current average price 3 months from now.

What is the cheapest day to fly from Charleston to Panama City?

Travelers seeking maximum savings on their Charleston to Panama City flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular airlines that fly from Charleston to Panama City?

The most popular airlines flying from Charleston to Panama City are American Airlines, Delta and United Airlines. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Charleston to Panama City?

Users have found that leaving on a Tuesday can be a cost-effective option. It’s possible to save up to 108% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Charleston to Panama City?

July is one of the best times of the year to fly to Panama City from Charleston. Prices for July average $504 per person but you can even find prices for as low as $234. The most expensive prices can be found in the month of March. Opting for a July flight can save you 35% on your journey compared to booking in March

Can I find deals for flights from Charleston to Panama City that include hotel bookings?

Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Charleston to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

Can I find deals for business class flights from Charleston to Panama City?

Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$327+ Flights from Charleston to Panama City

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Cheap flight deals from Charleston to Panama City

Round-trip from	$327 (American Airlines)
Popular in	March
Cheapest in	July
Average price	$331

From Charleston to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($118 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Find flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Wed 10/156:00 amCHS - PTY

1 stop9h 00mAmerican Airlines

Sat 10/253:19 pmPTY - CHS

1 stop7h 40mAmerican Airlines

Deal found 7/1

$327

Tue 9/26:20 amCHS - PTY

1 stop7h 30mDelta

Mon 9/82:05 pmPTY - CHS

1 stop8h 46mDelta

Deal found 7/1

$369

Tue 7/297:00 amCHS - PTY

1 stop12h 37mUnited Airlines

Tue 8/53:30 pmPTY - CHS

1 stop30h 15mUnited Airlines

Deal found 7/1

$378

Best flights from Charleston to Panama City
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Wed 10/156:00 amCHS - PTY

1 stop9h 00mAmerican Airlines

Sat 10/253:19 pmPTY - CHS

1 stop7h 40mAmerican Airlines

Deal found 7/1

$327

Tue 9/26:20 amCHS - PTY

1 stop7h 30mDelta

Mon 9/82:05 pmPTY - CHS

1 stop8h 46mDelta

Deal found 7/1

$369

Tue 7/297:00 amCHS - PTY

1 stop12h 37mUnited Airlines

Tue 8/53:30 pmPTY - CHS

1 stop30h 15mUnited Airlines

Deal found 7/1

$378

Tue 9/29:13 amCHS - PTY

3 stops25h 57mMultiple Airlines

Sun 9/73:20 amPTY - CHS

3 stops14h 45mMultiple Airlines

Deal found 7/1

$804

Last-minute flights from Charleston to Panama City
Discover last-minute flight deals from Charleston to Panama City. Data last updated July 3, 2025 and is based on user searches.

Tue 7/87:00 amCHS - PTY

1 stop12h 37mUnited Airlines

Wed 7/2310:00 amPTY - CHS

1 stop11h 45mUnited Airlines

Deal found 7/3

$433

Tue 7/86:02 pmCHS - PTY

2 stops19h 52mAmerican Airlines

Tue 7/221:55 pmPTY - CHS

2 stops19h 29mAmerican Airlines

Deal found 7/3

$438

Thu 7/102:50 pmCHS - PTY

2 stops26h 21mMultiple Airlines

Sun 7/209:22 amPTY - CHS

1 stop22h 21mMultiple Airlines

Deal found 7/2

$755

Tue 7/297:00 amCHS - PTY

1 stop12h 37mUnited Airlines

Tue 8/53:30 pmPTY - CHS

1 stop30h 15mUnited Airlines

Deal found 7/1

$378

Thu 7/316:02 pmCHS - PTY

2 stops19h 52mAmerican Airlines

Thu 8/73:30 pmPTY - CHS

1 stop7h 29mAmerican Airlines

Deal found 7/1

$374

Sat 8/165:15 amCHS - PTY

1 stop8h 35mDelta

Sat 8/232:05 pmPTY - CHS

1 stop8h 46mDelta

Deal found 7/2

$436

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 10/15

6:00 am-2:00 pm

1 stop9h 00m

Panama City Tocumen Intl

Sat 10/25

3:19 pm-11:59 pm

1 stop7h 40m

$327

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 9/2

6:20 am-12:50 pm

1 stop7h 30m

Panama City Tocumen Intl

Mon 9/8

2:05 pm-11:51 pm

1 stop8h 46m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 7/29

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Tue 8/5

3:30 pm-10:45 pm

1 stop30h 15m

$378

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 9/2

9:13 am-10:10 am

3 stops25h 57m

Panama City Tocumen Intl

Sun 9/7

3:20 am-7:05 pm

3 stops14h 45m

$804

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, October is the cheapest month in which you can book a flight from Charleston to Panama City (average of $478). Flying from Charleston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PTY?

One of the essential ways to save on airfare from Charleston to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 6% on airfare.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,982 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,982 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Charleston to Panama City round-trip?
Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $327. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $369 and $378, respectively. These flights start at 35% lower than the current average price 3 months from now.
Can I find deals for flights from Charleston to Panama City that include hotel bookings?
Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Charleston to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.
Can I find deals for business class flights from Charleston to Panama City?
Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Charleston to Panama City?
Currently, October is the cheapest month in which you can book a flight from Charleston to Panama City (average of $478). Flying from Charleston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Charleston to Panama City

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$268	Average$444	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$331	Average$476	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$362	Average$533	FlexibilityNo cancel fee	On-time71%

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$327+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Charleston to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Charleston to Panama City

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

What is the cheapest time of day to fly from CHS to PTY?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Charleston to Panama City round-trip?

Can I find deals for flights from Charleston to Panama City that include hotel bookings?

How can I find direct flights from Charleston to Panama City?

Can I find deals for business class flights from Charleston to Panama City?

What is the cheapest month to book a flight from Charleston to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charleston to Panama City

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Travel Smart

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.