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Charleston

$332+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Sep 16 — Sep 231
Wed 9/16
Wed 9/23
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.

This Faresmojo deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:20 pm -
1 stop8h 39m
Sat 9/126:00 am -
1 stop7h 58m
Deal found 8/13$615
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:30 pm -
2 stops17h 57m
Tue 10/67:00 am -
1 stop8h 14m
Deal found 8/15$641
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:00 am -
1 stop11h 11m
Thu 9/247:00 am -
1 stop13h 31m
Deal found 8/16$686
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:30 pm -
1 stop24h 02m
Thu 9/107:00 am -
1 stop13h 31m
Deal found 8/16$701
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:30 pm -
1 stop24h 02m
Fri 9/117:00 am -
1 stop13h 31m
Deal found 8/12$719
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:30 pm -
1 stop29h 41m
Sat 9/124:58 pm -
2 stops26h 39m
Deal found 8/14$724
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:39 pm -
2 stops22h 37m
Sat 9/126:39 pm -
2 stops18h 37m
Deal found 8/12$745

Find flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$615
(Faresmojo)

One-way from

$332
(Expedia)

Popular in

March

Cheapest in

December

Average price

$683
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
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From Panama City Tocumen Intl to Charleston
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One-way flight from Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Tue 9/29

3:30 pm-10:27 am

2 stops17h 57m

Charleston

Tue 10/6

4:58 pm-6:37 pm

2 stops26h 39m

$641
Quickest round-trip

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 9/21

10:00 am-10:11 pm

1 stop11h 11m

Charleston

Thu 9/24

7:00 am-7:31 pm

1 stop13h 31m

$686
Cheapest one-way

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 12/7

3:50 pm-11:52 am

2 stops20h 02m

$332

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 12/7

10:00 am-10:21 am

1 stop24h 21m

$335
Quickest one-way

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Sun 9/13

2:23 pm-11:59 pm

1 stop8h 36m

$391

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest month to book a flight from Panama City to Charleston?

Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $376). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Charleston?

Airfare is typical for this route at the moment.

Panama City to Charleston flights typically cost between $555 and $683 in September.
The cheapest round-trip price found within the last 5 days was $615 on JetBlue (Sep 3-Sep 12).

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated August 17, 2026.
Read through reviews of airlines operating flights from Panama City to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,945 reviews

Food

6.4

Boarding

7.5

Crew

7.9

Overall

7.1

Comfort

7.2

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Sherif,Aug 2026

YYZ - ORD

Terrible. Will not fly it again. Constant delays. Canceled flight because a pilot didn't show up the AA stated it was weather related. AA is also liars and didn't want to take responsibility or pay. Delayed luggage. Just horrible all the way around. Second time with this. Lost luggage on a previous flight. Back to Delta.
American Airlines
7.1
Good
11,945 reviews
American Airlines
7.1
Good
11,945 reviews

Food

6.4

Boarding

7.5

Crew

7.9

Overall

7.1

Comfort

7.2

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Sherif,Aug 2026

YYZ - ORD

Terrible. Will not fly it again. Constant delays. Canceled flight because a pilot didn't show up the AA stated it was weather related. AA is also liars and didn't want to take responsibility or pay. Delayed luggage. Just horrible all the way around. Second time with this. Lost luggage on a previous flight. Back to Delta.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $641, United Airlines can have you in Charleston from Panama City in 17h 57m. Airlines will cover a distance of 1645 mi.

  • What is the cheapest airline to fly from Panama City to Charleston round-trip?

    Currently priced at $431, American Airlines will fly you from Panama City to Charleston and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Users have found that American Airlines is 19% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Charleston?

    Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $376). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Charlotte flights
Panama City to Greenville flights
Panama City to Myrtle Beach flights

Top airline flying from Panama City to Charleston

Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$431Average$642FlexibilityNo cancel feeOn-time71%

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