$362+ Cheap flights from Panama City (PTY) to Charleston (CHS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Charleston
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to CharlestonExplore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:41 pm -
1 stop29h 21m
Mon 12/287:56 pm -
2 stops23h 42m
Deal found 10/17![United Airlines logo]()
$680
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
1 stop11h 04m
Mon 12/288:10 am -
1 stop13h 35m
Deal found 10/17![Delta logo]()
$767
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:41 pm -
1 stop23h 38m
Mon 11/93:29 pm -
2 stops23h 16m
Deal found 10/14![United Airlines logo]()
$778
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 am -
1 stop13h 59m
Mon 11/1611:12 am -
1 stop8h 50m
Deal found 10/15![United Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:41 pm -
2 stops25h 23m
Sun 11/17:05 pm -
1 stop24h 57m
Deal found 10/15![United Airlines logo]()
$808
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 10/14![Delta logo]()
$817
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:41 pm -
2 stops22h 47m
Mon 11/93:29 pm -
2 stops23h 16m
Deal found 10/14![United Airlines logo]()
$818
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 10/14![Delta logo]()
$826
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:13 pm -
1 stop8h 46m
Sun 11/297:21 am -
1 stop7h 13m
Deal found 10/14![American Airlines logo]()
$831
Best flights from Panama City to CharlestonDiscover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:41 pm -
2 stops21h 19m
Mon 12/287:56 pm -
2 stops23h 42m
Deal found 10/17![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/194:41 pm -
1 stop23h 19m
Thu 1/217:51 pm -
2 stops21h 21m
Deal found 10/18![United Airlines logo]()
$719
Last-minute flights from Panama City to CharlestonDiscover last-minute flight deals from Panama City to Charleston. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Charleston. Data last updated October 19, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:41 pm -
2 stops25h 23m
Sun 11/17:05 pm -
1 stop24h 57m
Deal found 10/15![United Airlines logo]()
$808
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:41 pm -
2 stops22h 47m
Mon 11/93:29 pm -
2 stops23h 16m
Deal found 10/14![United Airlines logo]()
$818
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 10/14![Delta logo]()
$826
This Avianca deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:30 am -
2 stops14h 02m
Mon 11/99:40 am -
2 stops16h 30m
Deal found 10/15![Multiple Airlines logo]()
$833
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:41 pm -
1 stop23h 38m
Mon 11/93:29 pm -
2 stops23h 16m
Deal found 10/14![United Airlines logo]()
$778
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 10/14![Delta logo]()
$817
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 am -
1 stop13h 59m
Mon 11/1611:12 am -
1 stop8h 50m
Deal found 10/15![United Airlines logo]()
$791
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:13 pm -
1 stop8h 46m
Sun 11/297:21 am -
1 stop7h 13m
Deal found 10/14![American Airlines logo]()
$831
One-way flights from Panama City to CharlestonSearch for one-way flight options from Panama City to Charleston. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Panama City to Charleston. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/243:28 pm -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Delta logo]()
$362
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/213:20 pm -
1 stop20h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/171:47 pm -
1 stop9h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:55 am -
1 stop13h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![United Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/234:55 pm -
1 stop17h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/233:20 pm -
1 stop8h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Delta logo]()
$402
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/223:20 pm -
1 stop24h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Delta logo]()
$410
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2310:00 am -
2 stops29h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![United Airlines logo]()
$413
Find flight deals from Panama City to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $680 (United Airlines) |
One-way from | $362 (Delta) |
Popular in | October |
Cheapest in | December |
Average price | $869 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Thu 12/24
3:28 pm-10:43 pm
1 stop7h 15m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$362
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Thu 1/21
3:20 pm-11:26 am
1 stop20h 06m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$364
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Tue 1/26
3:20 pm-6:54 pm
1 stop27h 34m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$364
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Wed 3/17
1:47 pm-12:08 am
1 stop9h 21m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$367
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Thu 12/24
8:55 am-10:02 pm
1 stop13h 07m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$373
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Sat 1/23
3:20 pm-11:56 pm
1 stop8h 36m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$402
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Sat 1/23
4:55 pm-10:13 am
1 stop17h 18m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$404
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Wed 12/23
4:41 pm-2:00 pm
2 stops21h 19m
Charleston
Mon 12/28
7:56 pm-7:38 pm
2 stops23h 42m
$680
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Tue 1/19
4:41 pm-4:00 pm
1 stop23h 19m
Charleston
Thu 1/21
7:51 pm-5:12 pm
2 stops21h 21m
$719
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
PTY-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Charleston
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated October 19, 2026.
Read through reviews of airlines operating flights from Panama City to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.1
Crew
7.9
Entertainment
6.8
Food
6.4
Boarding
7.4
Overall
7.0
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Comfort
7.1
Crew
7.9
Entertainment
6.8
Food
6.4
Boarding
7.4
Overall
7.0
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Alternative routes for Panama City to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 19, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Charleston by cabin class
Find flights from Panama City to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Charleston flights
Browse other Panama City and Charleston flight options. Last updated on October 19, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Charleston
Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$431 | Average$642 | FlexibilityNo cancel fee | On-time71% |