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$221+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2025.

Round-trip from

$312
(Delta)

One-way from

$221
(Delta)

Popular in

March

Cheapest in

October

Average price

$478
From Panama City Tocumen Intl to Charleston
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One-way flight from Panama City Tocumen Intl to Charleston
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Highest demand for flights based on searches. 27% potential increase in price ($196 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/153:30 pmPTY - CHS
2 stops19h 54mAmerican Airlines
Fri 8/225:38 amCHS - PTY
1 stop9h 52mAmerican Airlines
Deal found 7/1$390
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2810:55 pmPTY - CHS
1 stop8h 52mUnited Airlines
Mon 8/47:00 amCHS - PTY
1 stop12h 37mUnited Airlines
Deal found 6/30$467
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/273:20 amPTY - CHS
2 stops28h 08mMultiple Airlines
Mon 8/49:38 amCHS - PTY
1 stop11h 41mMultiple Airlines
Deal found 6/30$724

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 10/20

2:12 pm-11:41 pm

1 stop8h 29m

Charleston

Wed 10/22

5:30 am-12:47 pm

1 stop8h 17m

$312

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 10/19

3:19 pm-11:59 pm

1 stop7h 40m

Charleston

Wed 10/22

6:00 am-2:00 pm

1 stop9h 00m

$340

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 8/14

3:20 am-7:12 pm

2 stops14h 52m

Charleston

Fri 8/22

8:17 pm-4:30 pm

3 stops21h 13m

$840

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest time of day to fly from PTY to CHS?

Find hourly flight availability from Panama City to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 16% on flights from Panama City to Charleston by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Panama City to Charleston?

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated July 2, 2025.
Read through reviews of airlines operating flights from Panama City to Charleston, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Charleston round-trip?

    Currently priced at $312, Delta will fly you from Panama City to Charleston and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $340. Users have found that Delta is 38% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Charleston (average of $217). Flying from Panama City to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Folly Beach
Santee
Edisto Beach

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Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to Charleston

Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$423Average$501FlexibilityNo cancel feeOn-time71%

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