$342+ Cheap flights from Panama City (PTY) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to South CarolinaExplore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:00 am -
2 stops13h 44m
Tue 1/55:10 pm -
2 stops26h 52m
Deal found 9/7![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:02 pm -
1 stop17h 23m
Tue 11/1710:25 pm -
1 stop15h 48m
Deal found 9/6![American Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 am -
2 stops24h 35m
Mon 11/167:43 pm -
2 stops24h 19m
Deal found 9/5![United Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:41 pm -
2 stops21h 15m
Sun 11/17:19 pm -
2 stops24h 19m
Deal found 9/3![United Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:41 pm -
1 stop18h 11m
Fri 1/86:30 am -
1 stop10h 42m
Deal found 9/7![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:35 am -
1 stop23h 11m
Sat 1/26:20 am -
1 stop13h 18m
Deal found 9/7![United Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:41 pm -
2 stops25h 23m
Thu 11/57:52 pm -
2 stops18h 53m
Deal found 9/4![United Airlines logo]()
$655
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:24 pm -
1 stop8h 30m
Thu 11/56:00 am -
1 stop7h 59m
Deal found 9/4![Delta logo]()
$660
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:41 pm -
1 stop18h 05m
Sat 1/911:05 am -
1 stop8h 57m
Deal found 9/7![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1811:35 am -
1 stop23h 11m
Thu 1/77:47 pm -
2 stops24h 15m
Deal found 9/7![United Airlines logo]()
$669
This Trip.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:30 am -
2 stops18h 16m
Thu 11/510:18 pm -
2 stops18h 57m
Deal found 9/4![Multiple Airlines logo]()
$675
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:13 pm -
2 stops15h 15m
Thu 11/57:30 pm -
1 stop18h 43m
Deal found 9/4![American Airlines logo]()
$678
Best flights from Panama City to South CarolinaDiscover carefully curated flight deals from Panama City to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Panama City to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/144:41 pm -
1 stop29h 11m
Wed 2/177:47 pm -
2 stops24h 15m
Deal found 9/5![United Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
1 stop8h 09m
Sat 1/27:30 am -
1 stop12h 30m
Deal found 9/3![Delta logo]()
$637
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:02 pm -
1 stop20h 59m
Mon 11/98:14 pm -
1 stop17h 59m
Deal found 9/3![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/214:41 pm -
2 stops24h 15m
Mon 1/256:15 am -
2 stops13h 47m
Deal found 9/3![United Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:24 pm -
1 stop8h 30m
Thu 11/56:00 am -
1 stop7h 59m
Deal found 9/4![Delta logo]()
$660
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:00 am -
1 stop13h 00m
Mon 11/165:37 pm -
2 stops21h 08m
Deal found 9/3![United Airlines logo]()
$618
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:13 pm -
1 stop8h 46m
Thu 11/58:14 pm -
1 stop17h 59m
Deal found 9/4![American Airlines logo]()
$693
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:30 am -
1 stop22h 42m
Sun 11/17:19 pm -
2 stops24h 19m
Deal found 9/3![United Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/54:13 pm -
2 stops23h 16m
Thu 3/118:19 pm -
2 stops17h 21m
Deal found 9/3![American Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:23 pm -
1 stop8h 26m
Sat 10/318:00 am -
1 stop5h 59m
Deal found 9/6![Delta logo]()
$757
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2110:00 am -
1 stop11h 59m
Fri 1/86:30 am -
1 stop10h 42m
Deal found 9/7![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:00 am -
2 stops13h 44m
Sun 1/106:30 am -
1 stop8h 15m
Deal found 9/7![United Airlines logo]()
$636
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:23 pm -
1 stop8h 05m
Fri 10/26:00 am -
1 stop7h 58m
Deal found 9/6![Delta logo]()
$808
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1910:00 am -
1 stop11h 59m
Wed 1/66:30 am -
1 stop10h 42m
Deal found 9/7![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:55 pm -
1 stop22h 04m
Sat 1/96:30 am -
1 stop13h 32m
Deal found 9/7![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:41 pm -
1 stop23h 03m
Sat 1/28:07 am -
2 stops21h 03m
Deal found 9/4![United Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:41 pm -
2 stops25h 23m
Thu 11/57:52 pm -
2 stops18h 53m
Deal found 9/4![United Airlines logo]()
$655
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/53:20 pm -
1 stop8h 35m
Thu 3/117:00 am -
1 stop7h 00m
Deal found 9/3![Delta logo]()
$1,098
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1911:55 pm -
1 stop9h 28m
Sun 1/106:30 am -
1 stop8h 15m
Deal found 9/7![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops21h 34m
Mon 10/57:00 am -
1 stop13h 31m
Deal found 9/3![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:30 pm -
2 stops41h 14m
Fri 10/26:55 pm -
1 stop25h 36m
Deal found 9/6![United Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:45 am -
2 stops23h 01m
Tue 10/135:38 pm -
2 stops25h 59m
Deal found 9/3![United Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:00 am -
1 stop24h 21m
Mon 11/911:27 am -
1 stop8h 35m
Deal found 9/6![United Airlines logo]()
$1,074
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:16 pm -
3 stops19h 29m
Sat 10/315:00 am -
2 stops9h 02m
Deal found 9/6![American Airlines logo]()
$3,236
Last-minute flights from Panama City to South CarolinaDiscover last-minute flight deals from Panama City to South Carolina. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to South Carolina. Data last updated September 7, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:50 pm -
2 stops17h 27m
Fri 10/210:41 am -
2 stops24h 49m
Deal found 9/6![Multiple Airlines logo]()
$680
This Trip.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 am -
3 stops14h 44m
Thu 10/89:40 pm -
2 stops12h 35m
Deal found 9/3![Multiple Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops21h 34m
Mon 10/57:00 am -
1 stop13h 31m
Deal found 9/3![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops17h 16m
Sat 10/3110:37 am -
2 stops29h 08m
Deal found 9/6![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
2 stops27h 35m
Wed 10/217:00 am -
1 stop13h 31m
Deal found 9/3![United Airlines logo]()
$714
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:02 pm -
1 stop18h 45m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 9/3![American Airlines logo]()
$682
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:30 pm -
2 stops21h 50m
Fri 10/306:00 am -
2 stops14h 02m
Deal found 9/3![United Airlines logo]()
$691
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:23 pm -
1 stop7h 32m
Mon 10/199:40 pm -
1 stop11h 26m
Deal found 9/3![Multiple Airlines logo]()
$729
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:30 am -
1 stop22h 42m
Sun 11/17:19 pm -
2 stops24h 19m
Deal found 9/3![United Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:02 pm -
1 stop19h 30m
Sun 11/111:41 am -
1 stop26h 32m
Deal found 9/3![American Airlines logo]()
$725
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:02 pm -
1 stop17h 23m
Tue 11/1710:25 pm -
1 stop15h 48m
Deal found 9/6![American Airlines logo]()
$613
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:02 pm -
2 stops21h 03m
Mon 11/98:14 pm -
1 stop17h 59m
Deal found 9/3![American Airlines logo]()
$679
One-way flights from Panama City to South CarolinaSearch for one-way flight options from Panama City to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Panama City to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/263:20 pm -
1 stop20h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$342
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:34 pm -
2 stops20h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:41 pm -
2 stops21h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/244:41 pm -
2 stops21h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/223:20 pm -
1 stop24h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$382
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/244:55 pm -
1 stop7h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/254:41 pm -
1 stop29h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/264:55 pm -
2 stops22h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/224:55 pm -
2 stops22h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:33 pm -
2 stops13h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$432
This Faresmojo deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/123:20 pm -
1 stop8h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![JetBlue logo]()
$440
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/254:55 pm -
2 stops18h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$446
Find flight deals from Panama City to South Carolina
Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $604 (United Airlines) |
One-way from | $342 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Tue 1/26
3:20 pm-11:26 am
1 stop20h 06m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$342
Panama CityAugusta
PTY Panama City Tocumen Intl - AGS Augusta Bush Field
PTYAGS
Panama City Tocumen Intl
Fri 11/20
3:34 pm-12:19 pm
2 stops20h 45m
Augusta Bush Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$351
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sat 11/21
4:41 pm-1:42 pm
2 stops21h 01m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$367
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Sun 1/24
4:41 pm-1:51 pm
2 stops21h 10m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$380
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Fri 1/22
3:20 pm-3:39 pm
1 stop24h 19m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$382
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Tue 1/26
4:55 pm-3:32 pm
2 stops22h 37m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$425
Quickest round-trip
Panama CityGreenville
PTY Panama City Tocumen Intl - GSP Greenville
PTYGSP
Panama City Tocumen Intl
Tue 1/12
3:20 pm-11:37 pm
1 stop8h 17m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$440
Panama CityGreenville
PTY Panama City Tocumen Intl - GSP Greenville
PTYGSP
Panama City Tocumen Intl
Tue 1/12
4:55 pm-2:31 pm
2 stops21h 36m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$458
Panama CityAugusta
PTY Panama City Tocumen Intl - AGS Augusta Bush Field
PTYAGS
Panama City Tocumen Intl
Fri 11/20
3:29 pm-11:47 pm
1 stop8h 18m
Augusta Bush Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$488
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Sun 1/24
12:03 pm-5:06 pm
2 stops29h 03m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$498
Showing 1-10 of 38 resultsSorted by cheapest first
Best time to book a flight from Panama City to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
PTY-CHS
PTY-AGS
PTY-CLT
PTY-GSP
PTY-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to South Carolina
PTY-USSC
PTY-CHS
PTY-AGS
PTY-CLT
PTY-GSP
What is the cheapest month to book a flight from Panama City to South Carolina?
Currently, December is the cheapest month in which you can book a flight from Panama City to South Carolina (average of $376). Flying from Panama City to South Carolina in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City to South Carolina?
Airfare is above average for this route at the moment.
Panama City to South Carolina flights typically cost between $431 and $462 in October.The cheapest round-trip price found within the last 5 days was $626 on United Airlines (Oct 26-Nov 1).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 7, 2026.
Read through reviews of airlines operating flights from Panama City to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Comfort
7.2
Entertainment
6.8
Overall
7.1
Boarding
7.5
Crew
7.9
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Food
6.4
Comfort
7.2
Entertainment
6.8
Overall
7.1
Boarding
7.5
Crew
7.9
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Panama City and South Carolina flights
Browse other Panama City and South Carolina flight options. Last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Panama City to South Carolina flights
Consider these flights traveling from Panama City to South Carolina.
Top airline flying from Panama City to South Carolina
Discover the top airline that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$431 | Average$642 | FlexibilityNo cancel fee | On-time71% |