To save up to 9% on this flight, we recommend booking at least 58 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from South Carolina to Panama City from $567 1-2 weeks out and tickets from $602 for flights departing within the next 72 hours.
The best pricing can be found in the month of February. Prices to Panama City from South Carolina average $564. You can even find prices in February for less than $564, as users have found deals to Panama City from as low as $357. The month of December appears to be one of the more expensive times to travel to Panama City from South Carolina. Flying in the targeted month can save you up to 27%.