$290+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Panama City
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Last-minute
One-way
Cheapest flights from Detroit to Panama CityExplore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:25 pm
DTW
- PTY
1 stop30h 06m
Multiple Airlines
Tue 10/612:21 pm
PTY
- DTW
2 stops34h 06m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$606
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Sun 10/43:50 pm
PTY
- DTW
2 stops23h 50m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$609
This Expedia deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Sun 10/2511:25 am
PTY
- DTW
3 stops27h 25m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$615
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Fri 9/183:50 pm
PTY
- DTW
2 stops23h 50m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:46 pm
DTW
- PTY
1 stop24h 45m
Multiple Airlines
Mon 8/3112:21 pm
PTY
- DTW
2 stops28h 01m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$622
This Justfly.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Sat 9/193:50 pm
PTY
- DTW
2 stops31h 06m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$625
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:25 pm
DTW
- PTY
1 stop30h 06m
Multiple Airlines
Fri 9/2512:21 pm
PTY
- DTW
2 stops34h 06m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$627
This Expedia deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:45 pm
DTW
- PTY
2 stops26h 10m
Multiple Airlines
Sun 11/153:50 pm
PTY
- DTW
2 stops24h 00m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$628
This Expedia deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:30 pm
DTW
- PTY
3 stops22h 25m
Multiple Airlines
Fri 10/2311:25 am
PTY
- DTW
3 stops28h 07m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$630
This Orbitz deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 pm
DTW
- PTY
3 stops22h 25m
Multiple Airlines
Wed 9/163:50 pm
PTY
- DTW
2 stops23h 50m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$634
This Justfly.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:38 am
DTW
- PTY
2 stops36h 17m
Multiple Airlines
Fri 12/117:50 pm
PTY
- DTW
2 stops28h 06m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$635
Best flights from Detroit to Panama CityDiscover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Justfly.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Sat 9/193:50 pm
PTY
- DTW
2 stops31h 06m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:24 pm
DTW
- PTY
2 stops20h 24m
American Airlines
Fri 12/112:50 pm
PTY
- DTW
1 stop9h 06m
American Airlines
Deal found 7/28![American Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:45 pm
DTW
- PTY
1 stop17h 13m
Delta
Mon 9/212:23 pm
PTY
- DTW
1 stop17h 59m
Delta
Deal found 7/26![Delta logo]()
$781
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:15 am
DTW
- PTY
1 stop8h 57m
United Airlines
Fri 12/1111:35 am
PTY
- DTW
1 stop12h 09m
United Airlines
Deal found 7/28![United Airlines logo]()
$781
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:05 am
DTW
- PTY
2 stops29h 25m
Multiple Airlines
Tue 8/185:30 am
PTY
- DTW
2 stops41h 29m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$664
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:38 am
DTW
- PTY
2 stops36h 17m
Multiple Airlines
Fri 12/113:50 pm
PTY
- DTW
2 stops32h 06m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:15 am
DTW
- PTY
1 stop13h 22m
United Airlines
Mon 9/2810:00 am
PTY
- DTW
1 stop11h 30m
United Airlines
Deal found 7/25![United Airlines logo]()
$792
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:45 am
DTW
- PTY
1 stop10h 53m
United Airlines
Fri 11/134:41 pm
PTY
- DTW
1 stop23h 23m
United Airlines
Deal found 7/24![United Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:35 am
DTW
- PTY
2 stops12h 02m
United Airlines
Mon 9/2110:00 am
PTY
- DTW
2 stops22h 32m
United Airlines
Deal found 7/26![United Airlines logo]()
$876
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:26 am
DTW
- PTY
1 stop11h 05m
United Airlines
Thu 9/173:30 pm
PTY
- DTW
2 stops18h 57m
United Airlines
Deal found 7/27![United Airlines logo]()
$887
Last-minute flights from Detroit to Panama CityDiscover last-minute flight deals from Detroit to Panama City. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Panama City. Data last updated July 28, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Mon 8/33:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$737
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
DTW
- PTY
2 stops44h 55m
Multiple Airlines
Thu 8/133:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$728
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:05 am
DTW
- PTY
2 stops44h 50m
Multiple Airlines
Sun 8/163:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$744
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:05 am
DTW
- PTY
2 stops29h 25m
Multiple Airlines
Tue 8/185:30 am
PTY
- DTW
2 stops41h 29m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$664
This Justfly.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:05 am
DTW
- PTY
2 stops53h 25m
Multiple Airlines
Mon 8/243:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$773
This FlightHub deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:05 am
DTW
- PTY
2 stops29h 25m
Multiple Airlines
Thu 8/273:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$654
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:46 pm
DTW
- PTY
1 stop24h 45m
Multiple Airlines
Mon 8/3112:21 pm
PTY
- DTW
2 stops28h 01m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$622
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:05 am
DTW
- PTY
2 stops29h 25m
Multiple Airlines
Tue 9/15:30 am
PTY
- DTW
2 stops41h 29m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$698
This FlightHub deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 am
DTW
- PTY
2 stops29h 25m
Multiple Airlines
Wed 9/23:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$642
One-way flights from Detroit to Panama CitySearch for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$290
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:00 am
DTW
- PTY
2 stops28h 30m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$297
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:45 pm
DTW
- PTY
2 stops27h 10m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$304
This Priceline deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:05 am
DTW
- PTY
2 stops29h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DTW
- PTY
1 stop15h 31m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:18 am
DTW
- PTY
3 stops39h 17m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$364
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:05 am
DTW
- PTY
2 stops53h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am
DTW
- PTY
1 stop13h 02m
United Airlines
Deal found 7/28![United Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 am
DTW
- PTY
2 stops9h 54m
American Airlines
Deal found 7/28![American Airlines logo]()
$405
Find flight deals from Detroit to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $606 (Kiwi.com) |
One-way from | $290 (FlightHub) |
Popular in | April |
Cheapest in | January |
Average price | $827 |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Sun 9/13
6:00 am-10:30 am
2 stops29h 30m
Panama City Tocumen Intl
Sat 9/19
3:50 pm-11:56 pm
2 stops31h 06m
$625
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Sat 8/15
6:05 am-10:30 am
2 stops29h 25m
Panama City Tocumen Intl
Tue 8/18
5:30 am-11:59 pm
2 stops41h 29m
$664
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Thu 12/3
6:38 am-6:55 pm
2 stops36h 17m
Panama City Tocumen Intl
Fri 12/11
3:50 pm-11:56 pm
2 stops32h 06m
$691
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Thu 12/3
5:24 pm-1:48 pm
2 stops20h 24m
Panama City Tocumen Intl
Fri 12/11
2:50 pm-11:56 pm
1 stop9h 06m
$737
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Mon 9/14
8:45 pm-12:58 pm
1 stop17h 13m
Panama City Tocumen Intl
Mon 9/21
2:23 pm-9:22 am
1 stop17h 59m
$781
Quickest round-trip
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Thu 12/3
8:15 am-5:12 pm
1 stop8h 57m
Panama City Tocumen Intl
Fri 12/11
11:35 am-11:44 pm
1 stop12h 09m
$781
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Mon 9/21
6:15 am-6:37 pm
1 stop13h 22m
Panama City Tocumen Intl
Mon 9/28
10:00 am-10:30 pm
1 stop11h 30m
$792
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Thu 11/5
8:45 am-7:38 pm
1 stop10h 53m
Panama City Tocumen Intl
Fri 11/13
4:41 pm-4:04 pm
1 stop23h 23m
$795
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Mon 9/14
7:35 am-6:37 pm
2 stops12h 02m
Panama City Tocumen Intl
Mon 9/21
10:00 am-9:32 am
2 stops22h 32m
$876
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Thu 9/10
9:26 am-7:31 pm
1 stop11h 05m
Panama City Tocumen Intl
Thu 9/17
3:30 pm-11:27 am
2 stops18h 57m
$887
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Detroit to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
DTW-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $753). Flying from Detroit Metropolitan Wayne County Airport to Panama City in April is currently the most expensive (average of $1,093). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Panama City?
Airfare is below average for this route at the moment.
Detroit Metropolitan Wayne County Airport to Panama City flights typically cost between $709 and $1,156 in September.The cheapest round-trip price found within the last 5 days was $606 on Multiple Airlines (Sep 30-Oct 6).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 28, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Detroit and Panama City flights
Browse other Detroit and Panama City flight options. Last updated on July 28, 2026.
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Top 4 airlines flying from Detroit to Panama City
Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$611 | Average$934 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$655 | Average$958 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$663 | Average$821 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$708 | Average$839 | FlexibilityNo cancel fee | On-time69% |