$332+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to Panama CityExplore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:03 pm -
1 stop30h 28m
Mon 10/269:31 pm -
2 stops12h 41m
Deal found 9/4![Multiple Airlines logo]()
$672
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:03 pm -
1 stop30h 28m
Wed 10/289:31 pm -
2 stops13h 12m
Deal found 9/6![Multiple Airlines logo]()
$683
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:10 am -
2 stops20h 00m
Mon 11/165:30 am -
2 stops12h 38m
Deal found 9/7![Multiple Airlines logo]()
$690
This FlightHub deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 pm -
2 stops18h 00m
Sun 10/43:50 pm -
2 stops23h 50m
Deal found 9/4![Multiple Airlines logo]()
$693
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
2 stops29h 30m
Sat 10/173:50 pm -
2 stops31h 06m
Deal found 9/8![Multiple Airlines logo]()
$710
This FlightHub deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:38 am -
2 stops51h 57m
Tue 1/195:30 am -
2 stops18h 26m
Deal found 9/4![Multiple Airlines logo]()
$718
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:51 pm -
2 stops26h 40m
Fri 10/308:57 am -
1 stop29h 40m
Deal found 9/8![Multiple Airlines logo]()
$724
Best flights from Detroit to Panama CityDiscover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop8h 13m
Sat 12/123:13 pm -
2 stops19h 35m
Deal found 9/6![American Airlines logo]()
$787
This deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/911:15 am -
1 stop8h 47m
Sat 1/1611:35 am -
1 stop11h 02m
Deal found 9/5![United Airlines logo]()
$790
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
2 stops29h 30m
Sun 10/183:50 pm -
2 stops23h 59m
Deal found 9/5![Multiple Airlines logo]()
$835
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:00 am -
1 stop13h 02m
Fri 11/1310:00 am -
1 stop10h 58m
Deal found 9/5![United Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/55:25 am -
1 stop8h 11m
Tue 2/92:36 pm -
1 stop9h 23m
Deal found 9/6![American Airlines logo]()
$865
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:10 pm -
2 stops22h 35m
Tue 12/110:00 am -
2 stops12h 14m
Deal found 9/4![United Airlines logo]()
$823
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:30 am -
1 stop11h 32m
Mon 11/304:41 pm -
2 stops20h 19m
Deal found 9/4![United Airlines logo]()
$823
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
1 stop13h 02m
Tue 12/110:00 am -
2 stops12h 14m
Deal found 9/4![United Airlines logo]()
$823
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/209:30 am -
1 stop10h 32m
Tue 1/268:55 am -
1 stop13h 42m
Deal found 9/7![United Airlines logo]()
$865
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am -
1 stop13h 22m
Thu 10/299:30 am -
2 stops22h 56m
Deal found 9/7![United Airlines logo]()
$891
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/29:30 am -
1 stop10h 32m
Sat 3/611:55 pm -
2 stops13h 05m
Deal found 9/6![United Airlines logo]()
$896
Last-minute flights from Detroit to Panama CityDiscover last-minute flight deals from Detroit to Panama City. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Panama City. Data last updated September 8, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 pm -
2 stops18h 00m
Sun 10/43:50 pm -
2 stops23h 50m
Deal found 9/4![Multiple Airlines logo]()
$693
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
2 stops29h 30m
Sat 10/173:50 pm -
2 stops31h 06m
Deal found 9/8![Multiple Airlines logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:22 pm -
1 stop26h 09m
Fri 10/239:33 pm -
2 stops12h 38m
Deal found 9/4![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:03 pm -
1 stop30h 28m
Mon 10/269:31 pm -
2 stops12h 41m
Deal found 9/4![Multiple Airlines logo]()
$672
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:03 pm -
1 stop30h 28m
Wed 10/289:31 pm -
2 stops13h 12m
Deal found 9/6![Multiple Airlines logo]()
$683
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:51 pm -
2 stops26h 40m
Fri 10/308:57 am -
1 stop29h 40m
Deal found 9/8![Multiple Airlines logo]()
$724
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:29 pm -
1 stop28h 50m
Sun 11/110:00 am -
1 stop14h 44m
Deal found 9/3![Multiple Airlines logo]()
$743
One-way flights from Detroit to Panama CitySearch for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This FlightHub deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:30 pm -
2 stops18h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:51 pm -
2 stops26h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:13 pm -
2 stops14h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$376
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop13h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:51 pm -
2 stops26h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$458
This FlightHub deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
3 stops33h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Avianca logo]()
$492
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:15 am -
1 stop13h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$501
Find flight deals from Detroit to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $672 (Kiwi.com) |
One-way from | $332 (Justfly.com) |
Popular in | April |
Cheapest in | January |
Average price | $1,093 |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Tue 10/6
5:30 pm-10:30 am
2 stops18h 00m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Wed 10/28
6:10 am-2:10 am
2 stops21h 00m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
Quickest round-trip
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Wed 10/28
7:00 am-7:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$443
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Sat 12/5
6:00 am-2:13 pm
1 stop8h 13m
Panama City Tocumen Intl
Sat 12/12
3:13 pm-10:48 am
2 stops19h 35m
$787
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Sat 1/9
11:15 am-8:02 pm
1 stop8h 47m
Panama City Tocumen Intl
Sat 1/16
11:35 am-10:37 pm
1 stop11h 02m
$790
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Thu 11/5
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Fri 11/13
10:00 am-8:58 pm
1 stop10h 58m
$819
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Sat 11/21
4:10 pm-2:45 pm
2 stops22h 35m
Panama City Tocumen Intl
Tue 12/1
10:00 am-10:14 pm
2 stops12h 14m
$823
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Fri 11/20
8:30 am-8:02 pm
1 stop11h 32m
Panama City Tocumen Intl
Mon 11/30
4:41 pm-1:00 pm
2 stops20h 19m
$823
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Fri 11/20
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Tue 12/1
10:00 am-10:14 pm
2 stops12h 14m
$823
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Fri 10/9
6:00 am-10:30 am
2 stops29h 30m
Panama City Tocumen Intl
Sun 10/18
3:50 pm-4:49 pm
2 stops23h 59m
$835
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Detroit to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
DTW-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 8, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Detroit and Panama City flights
Browse other Detroit and Panama City flight options. Last updated on September 8, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Detroit to Panama City
Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$611 | Average$1,093 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$655 | Average$962 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$708 | Average$811 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$745 | Average$860 | FlexibilityNo cancel fee | On-time71% |