$301+ Cheap flights from St. Louis (STL) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PTY
Nov 26 — Dec 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Panama CityExplore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop7h 45m
Wed 12/168:55 am -
1 stop10h 46m
Deal found 10/22![United Airlines logo]()
$686
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:15 pm -
2 stops20h 58m
Tue 12/153:13 pm -
2 stops20h 39m
Deal found 10/24![American Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:30 am -
1 stop10h 08m
Tue 12/158:55 am -
1 stop10h 46m
Deal found 10/24![United Airlines logo]()
$706
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:40 pm -
2 stops21h 33m
Fri 12/184:33 pm -
2 stops21h 47m
Deal found 10/24![American Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop13h 02m
Mon 11/238:55 am -
1 stop14h 31m
Deal found 10/22![United Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:15 am -
2 stops13h 23m
Thu 12/174:41 pm -
2 stops19h 01m
Deal found 10/24![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:15 am -
1 stop12h 23m
Thu 11/268:55 am -
1 stop10h 43m
Deal found 10/22![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/63:00 pm -
1 stop27h 38m
Sun 12/1311:35 am -
1 stop11h 55m
Deal found 10/22![United Airlines logo]()
$732
Best flights from St. Louis to Panama CityDiscover carefully curated flight deals from St. Louis to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from St. Louis to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:15 am -
1 stop9h 57m
Wed 1/204:41 pm -
2 stops22h 47m
Deal found 10/21![United Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/36:15 am -
2 stops12h 47m
Thu 3/114:41 pm -
2 stops20h 34m
Deal found 10/23![United Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/256:10 am -
1 stop10h 02m
Thu 5/2010:00 am -
1 stop12h 06m
Deal found 10/26![United Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/155:34 pm -
2 stops20h 11m
Mon 3/223:41 pm -
2 stops29h 32m
Deal found 10/25![United Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop7h 45m
Wed 12/168:55 am -
1 stop10h 46m
Deal found 10/22![United Airlines logo]()
$686
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/206:10 am -
1 stop7h 35m
Thu 5/137:55 am -
1 stop14h 11m
Deal found 10/26![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/238:35 am -
1 stop7h 37m
Fri 5/2110:00 am -
1 stop12h 06m
Deal found 10/26![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/209:52 am -
1 stop9h 10m
Thu 5/2010:00 am -
1 stop12h 06m
Deal found 10/26![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/175:06 pm -
2 stops20h 39m
Sun 1/248:55 am -
2 stops15h 25m
Deal found 10/24![United Airlines logo]()
$706
Last-minute flights from St. Louis to Panama CityDiscover last-minute flight deals from St. Louis to Panama City. Data last updated October 27, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Panama City. Data last updated October 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:15 am -
1 stop12h 23m
Thu 11/268:55 am -
1 stop10h 43m
Deal found 10/22![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:15 am -
1 stop12h 23m
Fri 11/2710:00 am -
1 stop13h 00m
Deal found 10/22![United Airlines logo]()
$748
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:30 am -
1 stop10h 08m
Thu 11/268:55 am -
1 stop8h 51m
Deal found 10/22![United Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:30 am -
2 stops11h 32m
Tue 11/244:41 pm -
1 stop18h 21m
Deal found 10/22![United Airlines logo]()
$751
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 02m
Wed 11/253:29 pm -
1 stop9h 27m
Deal found 10/25![Delta logo]()
$756
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:00 am -
1 stop7h 38m
Fri 11/278:55 am -
1 stop10h 43m
Deal found 10/22![United Airlines logo]()
$763
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:00 am -
1 stop8h 13m
Wed 11/253:34 pm -
2 stops21h 57m
Deal found 10/25![American Airlines logo]()
$766
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop13h 02m
Mon 11/238:55 am -
1 stop14h 31m
Deal found 10/22![United Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop13h 02m
Wed 11/254:41 pm -
2 stops24h 02m
Deal found 10/22![United Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop13h 02m
Fri 11/278:55 am -
1 stop10h 43m
Deal found 10/22![United Airlines logo]()
$742
One-way flights from St. Louis to Panama CitySearch for one-way flight options from St. Louis to Panama City. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from St. Louis to Panama City. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/86:15 am -
1 stop12h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$301
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1910:07 am -
1 stop8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
1 stop10h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:05 am -
1 stop13h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$388
This BusinessClass deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/223:11 pm -
2 stops21h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![GOL logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:54 pm -
3 stops40h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:15 pm -
1 stop25h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$404
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:59 pm -
1 stop24h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![United Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:21 pm -
2 stops48h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:58 pm -
2 stops25h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/87:02 pm -
3 stops43h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$456
Find flight deals from St. Louis to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $647 (United Airlines) |
One-way from | $301 (United Airlines) |
Popular in | October |
Cheapest in | April |
Average price | $1,256 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from St. Louis to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Mon 2/8
6:15 am-7:38 pm
1 stop12h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$301
Quickest round-trip
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Fri 2/19
10:07 am-8:02 pm
1 stop8h 55m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$325
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Fri 12/11
5:25 am-7:38 pm
2 stops13h 13m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$357
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Sat 12/12
6:00 am-7:38 pm
1 stop12h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$357
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Mon 2/22
3:11 pm-1:47 pm
2 stops21h 36m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$390
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Mon 12/21
7:15 pm-9:45 pm
1 stop25h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$404
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Mon 2/8
7:02 pm-4:01 pm
3 stops43h 59m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$456
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Wed 12/23
7:15 pm-9:45 pm
1 stop25h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$494
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Fri 12/25
6:21 pm-8:19 pm
3 stops24h 58m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$506
St. LouisPanama City
STL Lambert-St Louis - PTY Panama City Tocumen Intl
STLPTY
Lambert-St Louis
Mon 1/11
6:15 am-5:12 pm
1 stop9h 57m
Panama City Tocumen Intl
Wed 1/20
4:41 pm-2:28 pm
2 stops22h 47m
$652
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from St. Louis with our price prediction graph.
STL-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 27, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from St. Louis to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Overall
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Panama City flight routes
Popular flights
Alternative routes for St. Louis to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Panama City by cabin class
Find flights from St. Louis to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Panama City flights
Browse other St. Louis and Panama City flight options. Last updated on October 27, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on October 27, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from St. Louis to Panama City
Discover the top 4 airlines that operate flights from St. Louis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$362 | Average$730 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$393 | Average$664 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$446 | Average$942 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$478 | Average$738 | FlexibilityNo cancel fee | On-timeN/A |