$296+ Cheap flights from Myrtle Beach (MYR) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — PTY
Oct 19 — Oct 261
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to Panama CityExplore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:27 am -
1 stop8h 35m
Tue 11/1710:00 am -
1 stop24h 21m
Deal found 9/17![United Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:52 pm -
2 stops24h 21m
Mon 11/93:13 pm -
2 stops20h 29m
Deal found 9/18![American Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:27 am -
1 stop8h 35m
Mon 11/910:00 am -
1 stop24h 21m
Deal found 9/18![United Airlines logo]()
$783
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:10 pm -
2 stops21h 45m
Tue 11/1712:03 pm -
1 stop21h 10m
Deal found 9/17![Multiple Airlines logo]()
$836
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:41 pm -
2 stops29h 50m
Mon 11/912:03 pm -
1 stop21h 52m
Deal found 9/18![Multiple Airlines logo]()
$868
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:27 am -
1 stop8h 35m
Sat 11/710:00 am -
1 stop24h 21m
Deal found 9/15![United Airlines logo]()
$913
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:10 am -
2 stops9h 03m
Tue 11/173:13 pm -
2 stops20h 29m
Deal found 9/18![American Airlines logo]()
$973
Best flights from Myrtle Beach to Panama CityDiscover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:27 am -
1 stop8h 35m
Tue 11/1710:00 am -
1 stop24h 21m
Deal found 9/17![United Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/15:55 pm -
2 stops22h 00m
Sun 2/284:04 pm -
2 stops19h 40m
Deal found 9/15![American Airlines logo]()
$683
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:00 am -
1 stop7h 55m
Sun 2/283:20 pm -
1 stop8h 15m
Deal found 9/19![Delta logo]()
$820
Last-minute flights from Myrtle Beach to Panama CityDiscover last-minute flight deals from Myrtle Beach to Panama City. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Panama City. Data last updated September 19, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:38 am -
1 stop9h 53m
Sun 10/259:30 am -
1 stop23h 51m
Deal found 9/17![United Airlines logo]()
$1,275
One-way flights from Myrtle Beach to Panama CitySearch for one-way flight options from Myrtle Beach to Panama City. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Myrtle Beach to Panama City. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/113:36 pm -
2 stops22h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:00 am -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:27 am -
1 stop8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:12 pm -
3 stops26h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$492
This KAYAK deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:10 am -
2 stops9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![GOL logo]()
$616
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:35 pm -
3 stops17h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$1,446
Find flight deals from Myrtle Beach to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $657 (United Airlines) |
One-way from | $296 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Mon 1/11
3:36 pm-1:36 pm
2 stops22h 00m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$296
Quickest round-trip
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Mon 1/11
6:00 am-1:55 pm
1 stop7h 55m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$302
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Thu 11/12
11:27 am-8:02 pm
1 stop8h 35m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$305
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Mon 1/11
6:12 pm-8:31 pm
3 stops26h 19m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$492
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Thu 11/12
11:27 am-8:02 pm
1 stop8h 35m
Panama City Tocumen Intl
Tue 11/17
10:00 am-10:21 am
1 stop24h 21m
$657
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Mon 2/1
5:55 pm-3:55 pm
2 stops22h 00m
Panama City Tocumen Intl
Sun 2/28
4:04 pm-11:44 am
2 stops19h 40m
$683
Myrtle BeachPanama City
MYR Myrtle Beach Intl - PTY Panama City Tocumen Intl
MYRPTY
Myrtle Beach Intl
Mon 2/1
6:00 am-1:55 pm
1 stop7h 55m
Panama City Tocumen Intl
Sun 2/28
3:20 pm-11:35 pm
1 stop8h 15m
$820
Sorted by cheapest first
Compare providers for flights from Myrtle Beach to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
MYR-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Myrtle Beach
Panama City flight routes
Popular flights