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$291+ Cheap flights from Myrtle Beach (MYR) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — PTY
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 3, 2025.

Round-trip from

$496
(Avianca Connect)

One-way from

$291
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$631
From Myrtle Beach Intl to Panama City Tocumen Intl
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One-way flight from Myrtle Beach Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 7% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Myrtle Beach to Panama City

Cheapest flights from Myrtle Beach to Panama City
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This Avianca Connect deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/156:45 amMYR - PTY
2 stops19h 00mMultiple Airlines
jue. 8/213:20 amPTY - MYR
2 stops15h 25mMultiple Airlines
Deal found 7/1$496
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/155:06 pmMYR - PTY
2 stops22h 24mAmerican Airlines
vie. 8/223:30 pmPTY - MYR
2 stops17h 53mAmerican Airlines
Deal found 7/1$532
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/176:00 amMYR - PTY
1 stop7h 55mDelta
mié. 9/242:10 pmPTY - MYR
1 stop8h 39mDelta
Deal found 7/2$633
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/1910:23 amMYR - PTY
1 stop10h 08mUnited Airlines
jue. 7/2410:55 pmPTY - MYR
1 stop10h 01mUnited Airlines
Deal found 7/1$677

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Myrtle Beach

Fly to

Panama City

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

vie. 8/15

6:45 am-12:45 am

2 stops19h 00m

Panama City Tocumen Intl

jue. 8/21

3:20 am-7:45 pm

2 stops15h 25m

$496

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

vie. 8/15

5:06 pm-2:30 pm

2 stops22h 24m

Panama City Tocumen Intl

vie. 8/22

3:30 pm-10:23 am

2 stops17h 53m

$532

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

mié. 9/17

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

mié. 9/24

2:10 pm-11:49 pm

1 stop8h 39m

$633

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

sáb. 7/19

10:23 am-7:31 pm

1 stop10h 08m

Panama City Tocumen Intl

jue. 7/24

10:55 pm-9:56 am

1 stop10h 01m

$677

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

sáb. 7/12

7:00 am-2:15 pm

2 stops8h 15m

$291

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

sáb. 7/12

1:24 pm-10:25 am

3 stops46h 01m

$306

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

sáb. 7/12

10:23 am-7:31 pm

1 stop10h 08m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama City

What is the cheapest month to book a flight from Myrtle Beach to Panama City?

Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to Panama City (average of $478). Flying from Myrtle Beach to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated julio 3, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Panama City, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,970 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,845 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to Panama City round-trip?

    Cheapflights users have booked flights from Myrtle Beach to Panama City round-trip from $532. Other airlines that can offer you cheap pricing are Delta, from $633, and United Airlines, from $677. Users have found that American Airlines is 14% cheaper than the other options available to this destination.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to Panama City (average of $478). Flying from Myrtle Beach to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Myrtle Beach to Panama City

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Top 2 airlines flying from Myrtle Beach to Panama City

Discover the top 2 airlines that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$437Average$570FlexibilityNo cancel feeOn-time71%
DeltaCheapest$457Average$617FlexibilityNo cancel feeOn-timeN/A

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