$266+ Cheap flights from O'Hare Intl (ORD) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
Oct 22 — Oct 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from O'Hare Intl to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago O'Hare Intl to Panama City Tocumen Intl are usually found in March or April, booked 31 days in advance, depart on a Wednesday or Thursday and return on a Saturday
Cheap flight deals from O'Hare Intl to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from O'Hare Intl to Panama CityExplore the most affordable flight options available from O'Hare Intl to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from O'Hare Intl to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:13 pm -
Nonstop5h 24m
Mon 11/238:05 am -
Nonstop5h 41m
Deal found 9/17![Copa Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:55 am -
1 stop11h 43m
Mon 11/234:41 pm -
1 stop9h 04m
Deal found 9/17![United Airlines logo]()
$607
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:27 am -
1 stop7h 32m
Wed 11/113:29 pm -
2 stops28h 01m
Deal found 9/17![Delta logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/93:13 pm -
1 stop17h 29m
Deal found 9/21![American Airlines logo]()
$612
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:30 pm -
1 stop25h 50m
Mon 11/94:10 pm -
1 stop29h 20m
Deal found 9/18![Avianca logo]()
$615
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Thu 12/33:13 pm -
2 stops17h 13m
Deal found 9/17![American Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:49 am -
1 stop30h 15m
Thu 11/263:29 pm -
2 stops20h 10m
Deal found 9/20![Delta logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Fri 12/43:13 pm -
1 stop17h 47m
Deal found 9/22![American Airlines logo]()
$627
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:30 pm -
1 stop17h 45m
Sun 11/810:05 am -
1 stop11h 25m
Deal found 9/17![Avianca logo]()
$640
Best flights from O'Hare Intl to Panama CityDiscover carefully curated flight deals from O'Hare Intl to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from O'Hare Intl to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:35 am -
Nonstop5h 26m
Mon 1/187:28 pm -
Nonstop5h 39m
Deal found 9/19![Copa Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop12h 02m
Fri 11/2710:00 am -
1 stop15h 01m
Deal found 9/17![United Airlines logo]()
$607
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/227:35 am -
Nonstop5h 26m
Sun 1/318:08 am -
Nonstop5h 38m
Deal found 9/17![Copa Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/208:00 pm -
1 stop17h 45m
Fri 3/263:41 pm -
1 stop18h 26m
Deal found 9/20![United Airlines logo]()
$607
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/62:13 pm -
Nonstop5h 23m
Wed 3/107:04 pm -
Nonstop5h 40m
Deal found 9/17![Copa Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/225:30 am -
1 stop10h 42m
Sun 1/314:41 pm -
1 stop9h 02m
Deal found 9/17![United Airlines logo]()
$607
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/112:13 pm -
Nonstop5h 23m
Mon 2/157:28 pm -
Nonstop5h 43m
Deal found 9/19![Copa Airlines logo]()
$592
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:13 pm -
Nonstop5h 25m
Mon 2/17:28 pm -
Nonstop5h 43m
Deal found 9/20![Copa Airlines logo]()
$592
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:13 pm -
Nonstop5h 24m
Tue 11/248:05 am -
Nonstop5h 41m
Deal found 9/20![Copa Airlines logo]()
$592
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/142:13 pm -
Nonstop5h 25m
Sat 1/168:08 am -
Nonstop5h 38m
Deal found 9/18![Copa Airlines logo]()
$612
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:35 am -
Nonstop5h 26m
Sun 11/298:05 am -
Nonstop5h 41m
Deal found 9/17![Copa Airlines logo]()
$709
Last-minute flights from O'Hare Intl to Panama CityDiscover last-minute flight deals from O'Hare Intl to Panama City. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Panama City. Data last updated September 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop7h 16m
Thu 10/82:02 pm -
1 stop17h 45m
Deal found 9/18![American Airlines logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:35 am -
1 stop12h 39m
Fri 10/1611:53 am -
1 stop11h 54m
Deal found 9/18![Multiple Airlines logo]()
$709
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:29 pm -
1 stop17h 33m
Thu 4/81:49 pm -
1 stop10h 38m
Deal found 9/21![American Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:29 pm -
1 stop17h 33m
Wed 4/141:49 pm -
1 stop10h 38m
Deal found 9/20![American Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:55 pm -
2 stops16h 07m
Wed 10/212:02 pm -
2 stops17h 23m
Deal found 9/17![American Airlines logo]()
$721
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:20 pm -
1 stop14h 55m
Mon 10/2610:05 am -
1 stop11h 25m
Deal found 9/18![Avianca logo]()
$706
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:30 pm -
1 stop22h 32m
Tue 10/272:02 pm -
2 stops17h 25m
Deal found 9/19![American Airlines logo]()
$722
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:30 pm -
1 stop15h 45m
Wed 10/282:30 am -
1 stop19h 00m
Deal found 9/19![Avianca logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
1 stop7h 57m
Wed 11/43:13 pm -
1 stop20h 52m
Deal found 9/22![American Airlines logo]()
$716
One-way flights from O'Hare Intl to Panama CitySearch for one-way flight options from O'Hare Intl to Panama City. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from O'Hare Intl to Panama City. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/132:13 pm -
Nonstop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:55 am -
1 stop11h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![United Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/18:55 pm -
2 stops15h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![American Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/58:55 pm -
2 stops15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:55 am -
1 stop11h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/109:06 pm -
2 stops15h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:04 am -
1 stop12h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:43 pm -
1 stop20h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:15 am -
2 stops30h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$368
This KAYAK deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/44:34 pm -
2 stops20h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![GOL logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:26 am -
1 stop10h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:15 am -
2 stops22h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$379
Find flight deals from O'Hare Intl to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $592 (Copa Airlines) |
One-way from | $266 (Copa Airlines) |
Popular in | September |
Cheapest in | March |
Average price | $837 |
Good round-trip deal | $533 or less |
Good one-way deal | $249 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Wed 1/13
2:13 pm-8:38 pm
Nonstop5h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$266
Quickest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Mon 3/1
7:35 am-1:54 pm
Nonstop5h 19m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$266
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Sun 11/22
2:13 pm-8:37 pm
Nonstop5h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$266
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Sun 1/10
9:27 pm-5:12 pm
1 stop18h 45m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$271
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Wed 11/18
6:55 am-7:38 pm
1 stop11h 43m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$271
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 11/20
6:55 am-7:38 pm
1 stop11h 43m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$348
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Tue 10/13
8:04 am-8:19 pm
1 stop12h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$386
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 10/16
6:00 am-8:31 pm
2 stops38h 31m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$407
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 11/12
2:13 pm-8:37 pm
Nonstop5h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$425
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Tue 1/12
7:35 am-2:01 pm
Nonstop5h 26m
Panama City Tocumen Intl
Mon 1/18
7:28 pm-12:07 am
Nonstop5h 39m
$592
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from O'Hare Intl with our price prediction graph.
ORD-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Chicago O'Hare Intl Airport to Panama City?
The best time to book flights from Chicago O'Hare Intl Airport to Panama City is 30 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Panama City?
Currently, March is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Panama City (average of $596). Flying from Chicago O'Hare Intl Airport to Panama City in September is currently the most expensive (average of $837). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to PTY?
Find hourly flight availability from O'Hare Intl to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2026.
One of the essential ways to save on airfare from Chicago O'Hare Intl Airport to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to Panama City?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Panama City. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Panama City flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How often are flights from Chicago to Panama City delayed?
About 12% of weekly flights between Chicago and Panama City have experienced delays in the past year, with the average delay time being 122 minutes.
What is the most punctual flight time for Chicago to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Chicago to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
The best insider tips for Chicago O'Hare Intl Airport to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago O'Hare Intl Airport to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 22, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from O'Hare Intl
Panama City flight routes
Popular flights
Alternative routes for O'Hare Intl to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from O'Hare Intl to Panama City by cabin class
Find flights from O'Hare Intl to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
O'Hare Intl and Panama City flights
Browse other O'Hare Intl and Panama City flight options. Last updated on September 22, 2026.
Other flights from O'Hare Intl
Browse through other flights departing from O'Hare Intl. Flights are based on user searches made on Cheapflights and were last updated on September 22, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from O'Hare Intl to Panama City
Discover the top 4 airlines that operate flights from O'Hare Intl to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$316 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$465 | Average$682 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$577 | Average$767 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$596 | Average$730 | FlexibilityNo cancel fee | On-time71% |