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Greenville

$321+ Cheap flights from Panama City (PTY) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — GSP
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Panama City to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$513
(Delta)

One-way from

$321
(American Airlines)
From Panama City Tocumen Intl to Greenville
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One-way flight from Panama City Tocumen Intl to Greenville
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Find flight deals from Panama City to Greenville

Cheapest flights from Panama City to Greenville
Explore the most affordable flight options available from Panama City to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/232:10 pmPTY - GSP
1 stop27h 45mDelta
Fri 9/264:35 pmGSP - PTY
1 stop21h 20mDelta
Deal found 7/2$513
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/311:55 pmPTY - GSP
2 stops19h 16mAmerican Airlines
Fri 8/86:05 pmGSP - PTY
1 stop21h 25mAmerican Airlines
Deal found 7/3$573
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/243:30 pmPTY - GSP
1 stop29h 30mUnited Airlines
Fri 8/87:00 amGSP - PTY
1 stop10h 12mUnited Airlines
Deal found 7/3$577
This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/303:20 amPTY - GSP
3 stops34h 55mMultiple Airlines
Fri 8/84:05 pmGSP - PTY
3 stops25h 25mMultiple Airlines
Deal found 7/3$678

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Panama City to Greenville that are best for you.

Fly from

Panama City

Fly to

Greenville

Route

Depart

Return

Price

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Tue 9/23

2:10 pm-6:55 pm

1 stop27h 45m

Greenville

Fri 9/26

4:35 pm-12:55 pm

1 stop21h 20m

$513

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 7/31

1:55 pm-10:11 am

2 stops19h 16m

Greenville

Fri 8/8

6:05 pm-2:30 pm

1 stop21h 25m

$573

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 7/24

3:30 pm-10:00 pm

1 stop29h 30m

Greenville

Fri 8/8

7:00 am-4:12 pm

1 stop10h 12m

$577

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Wed 7/30

3:20 am-3:15 pm

3 stops34h 55m

Greenville

Fri 8/8

4:05 pm-4:30 pm

3 stops25h 25m

$678

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Sun 10/5

3:31 pm-11:56 pm

1 stop7h 25m

$321

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Sat 10/4

3:20 am-8:44 pm

2 stops16h 24m

$539

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Sun 10/5

9:04 am-2:11 pm

3 stops28h 07m

$4,469

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Panama City to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Greenville

What is the cheapest month to book a flight from Panama City to Greenville?

Currently, January is the cheapest month in which you can book a flight from Panama City to Greenville (average of $329). Flying from Panama City to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to GSP?

Find hourly flight availability from Panama City to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Greenville as you normally would.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 3, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Panama City to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Greenville round-trip?

    Our cheapest airline available from Panama City to Greenville is Delta. Our recent data shows that you can find tickets from as low as $513 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $573 and $577 round-trip.

  • Can I find deals for flights from Panama City to Greenville that include hotel bookings?

    Yes. In addition to deals on Panama City to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Greenville.

  • Can I find deals for business class flights from Panama City to Greenville?

    Yes. Cheapflights offers flight deals from Panama City to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Greenville (average of $329). Flying from Panama City to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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