$346+ Cheap flights from Panama City (PTY) to Indianapolis (IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Nov 8 — Nov 151
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Indianapolis
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Best
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Cheapest flights from Panama City to IndianapolisExplore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2026.
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2026.
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:41 pm -
2 stops20h 24m
Tue 1/58:50 am -
1 stop11h 12m
Deal found 10/7![United Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:33 pm -
1 stop29h 58m
Tue 1/55:15 am -
1 stop10h 18m
Deal found 10/7![American Airlines logo]()
$671
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/198:55 am -
2 stops15h 04m
Tue 1/57:00 am -
2 stops13h 02m
Deal found 10/8![United Airlines logo]()
$676
This KAYAK deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:41 pm -
1 stop23h 03m
Mon 1/49:05 am -
1 stop8h 07m
Deal found 10/8![Copa Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1911:55 pm -
2 stops13h 10m
Sun 1/37:50 am -
1 stop12h 12m
Deal found 10/8![United Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/163:13 pm -
2 stops23h 40m
Sun 1/39:17 pm -
2 stops18h 16m
Deal found 10/7![American Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:00 am -
2 stops23h 48m
Tue 11/179:00 am -
1 stop10h 38m
Deal found 10/4![United Airlines logo]()
$744
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:41 pm -
2 stops22h 20m
Sun 1/35:30 am -
2 stops11h 42m
Deal found 10/7![United Airlines logo]()
$750
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:45 am -
1 stop9h 15m
Mon 10/268:00 am -
1 stop12h 02m
Deal found 10/5![United Airlines logo]()
$753
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:29 pm -
1 stop7h 49m
Tue 11/176:00 am -
1 stop8h 02m
Deal found 10/7![Delta logo]()
$765
Best flights from Panama City to IndianapolisDiscover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 9, 2026.
Discover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 9, 2026.
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:41 pm -
2 stops20h 24m
Tue 1/58:50 am -
1 stop11h 12m
Deal found 10/7![United Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:41 pm -
2 stops20h 24m
Mon 1/45:30 am -
2 stops11h 42m
Deal found 10/8![United Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/198:55 am -
2 stops15h 04m
Tue 1/57:00 am -
2 stops13h 02m
Deal found 10/8![United Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1911:55 pm -
2 stops13h 10m
Mon 1/45:30 am -
2 stops11h 42m
Deal found 10/8![United Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:00 am -
2 stops13h 59m
Tue 1/55:10 am -
2 stops14h 52m
Deal found 10/7![United Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:00 am -
2 stops23h 48m
Tue 11/179:00 am -
1 stop10h 38m
Deal found 10/4![United Airlines logo]()
$744
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:45 am -
1 stop9h 15m
Mon 10/268:00 am -
1 stop12h 02m
Deal found 10/5![United Airlines logo]()
$753
Last-minute flights from Panama City to IndianapolisDiscover last-minute flight deals from Panama City to Indianapolis. Data last updated October 9, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Indianapolis. Data last updated October 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:45 am -
2 stops21h 31m
Sun 10/187:00 am -
1 stop12h 37m
Deal found 10/3![United Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:45 am -
1 stop9h 15m
Mon 10/268:00 am -
1 stop12h 02m
Deal found 10/5![United Airlines logo]()
$753
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:02 pm -
2 stops22h 20m
Mon 10/267:12 pm -
2 stops18h 50m
Deal found 10/5![American Airlines logo]()
$779
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:00 am -
2 stops23h 48m
Tue 11/179:00 am -
1 stop10h 38m
Deal found 10/4![United Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:29 pm -
1 stop7h 49m
Tue 11/176:00 am -
1 stop8h 02m
Deal found 10/7![Delta logo]()
$765
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:29 pm -
1 stop9h 11m
Sun 11/296:00 am -
1 stop8h 02m
Deal found 10/8![Delta logo]()
$780
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:34 pm -
2 stops17h 53m
Sun 11/299:04 pm -
2 stops17h 30m
Deal found 10/8![American Airlines logo]()
$820
One-way flights from Panama City to IndianapolisSearch for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 9, 2026.
Search for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 9, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/302:41 pm -
1 stop9h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![American Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:29 pm -
1 stop9h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Delta logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:34 pm -
2 stops19h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$490
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:24 pm -
1 stop9h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Delta logo]()
$518
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:05 am -
3 stops32h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:02 pm -
2 stops21h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![American Airlines logo]()
$552
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:33 pm -
3 stops44h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$687
Find flight deals from Panama City to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $637 (United Airlines) |
One-way from | $346 (American Airlines) |
Popular in | June |
Cheapest in | April |
Average price | $711 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 9, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 12/30
2:41 pm-11:55 pm
1 stop9h 14m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$346
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Fri 11/20
3:29 pm-12:40 am
1 stop9h 11m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$484
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Fri 11/20
3:34 pm-11:33 am
2 stops19h 59m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$490
Quickest round-trip
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Sat 10/17
2:24 pm-12:25 am
1 stop9h 01m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$518
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Fri 11/20
10:05 am-6:35 pm
3 stops32h 30m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$546
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Tue 12/22
4:41 pm-1:05 pm
2 stops20h 24m
Indianapolis
Tue 1/5
8:50 am-8:02 pm
1 stop11h 12m
$637
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Thu 12/17
4:41 pm-1:05 pm
2 stops20h 24m
Indianapolis
Mon 1/4
5:30 am-5:12 pm
2 stops11h 42m
$637
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Sat 12/19
8:55 am-11:59 pm
2 stops15h 04m
Indianapolis
Tue 1/5
7:00 am-8:02 pm
2 stops13h 02m
$676
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Sat 12/19
11:55 pm-1:05 pm
2 stops13h 10m
Indianapolis
Mon 1/4
5:30 am-5:12 pm
2 stops11h 42m
$676
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Fri 12/18
10:00 am-11:59 pm
2 stops13h 59m
Indianapolis
Tue 1/5
5:10 am-8:02 pm
2 stops14h 52m
$676
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Panama City to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
PTY-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Indianapolis
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated October 9, 2026.
See what other customers who have flown with Copa Airlines and United Airlines from Panama City to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Comfort
7.4
Food
6.9
Entertainment
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Overall
7.6
Comfort
7.4
Food
6.9
Entertainment
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Overall
7.6
Comfort
7.4
Food
6.9
Entertainment
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsGreenwood
Plainfield
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Noblesville
Bloomington
Speedway
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 9, 2026.
Panama City and Indianapolis flights
Browse other Panama City and Indianapolis flight options. Last updated on October 9, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on October 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Indianapolis
Discover the top 2 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$864 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$468 | Average$643 | FlexibilityNo cancel fee | On-time70% |