$277+ Cheap flights from Charleston (CHS) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
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Cheapest flights from Charleston to PanamaExplore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:21 am -
1 stop7h 13m
Wed 12/23:13 pm -
1 stop7h 00m
Deal found 9/29![American Airlines logo]()
$627
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:15 pm -
2 stops28h 57m
Mon 12/710:00 am -
1 stop13h 59m
Deal found 9/29![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
1 stop13h 02m
Wed 11/410:00 am -
1 stop13h 59m
Deal found 9/29![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop13h 02m
Sun 12/610:00 am -
1 stop13h 59m
Deal found 9/25![United Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:26 pm -
1 stop28h 36m
Wed 12/98:55 am -
1 stop13h 04m
Deal found 9/25![United Airlines logo]()
$671
This KAYAK deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:23 am -
1 stop9h 39m
Mon 12/710:00 am -
1 stop13h 59m
Deal found 9/29![Copa Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 pm -
2 stops25h 02m
Thu 11/1910:00 am -
1 stop13h 59m
Deal found 9/28![United Airlines logo]()
$678
This Ovago deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
2 stops13h 38m
Mon 2/110:00 am -
1 stop13h 19m
Deal found 9/28![Copa Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:32 pm -
2 stops17h 41m
Fri 11/203:34 pm -
1 stop8h 18m
Deal found 9/29![American Airlines logo]()
$683
Best flights from Charleston to PanamaDiscover carefully curated flight deals from Charleston to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Charleston to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:15 pm -
2 stops28h 57m
Mon 12/710:00 am -
1 stop13h 59m
Deal found 9/28![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
1 stop13h 02m
Wed 11/410:00 am -
1 stop13h 59m
Deal found 9/29![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:56 pm -
2 stops24h 06m
Tue 12/1511:35 am -
2 stops23h 28m
Deal found 9/27![United Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:40 pm -
2 stops24h 22m
Tue 1/194:41 pm -
1 stop23h 31m
Deal found 9/29![United Airlines logo]()
$677
Last-minute flights from Charleston to PanamaDiscover last-minute flight deals from Charleston to Panama. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama. Data last updated September 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:44 pm -
2 stops19h 18m
Tue 11/33:13 pm -
1 stop6h 49m
Deal found 9/29![American Airlines logo]()
$688
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop8h 02m
Tue 10/272:02 pm -
1 stop8h 57m
Deal found 9/25![American Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop8h 14m
Wed 10/289:30 am -
1 stop13h 29m
Deal found 9/25![United Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop7h 59m
Wed 10/282:24 pm -
1 stop8h 35m
Deal found 9/29![Delta logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:08 pm -
2 stops17h 54m
Thu 10/292:02 pm -
2 stops21h 31m
Deal found 9/28![American Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:30 am -
1 stop8h 15m
Thu 10/293:41 pm -
1 stop23h 38m
Deal found 9/25![United Airlines logo]()
$790
One-way flights from Charleston to PanamaSearch for one-way flight options from Charleston to Panama. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Charleston to Panama. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
1 stop7h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:00 am -
2 stops13h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:40 pm -
2 stops24h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![United Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/53:00 pm -
3 stops53h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2810:15 pm -
3 stops21h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$560
Find flight deals from Charleston to Panama
Keep the following information in mind while searching for Charleston to Panama flight deals. Data was last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $627 (American Airlines) |
One-way from | $277 (American Airlines) |
Popular in | November |
Cheapest in | March |
Average price | $777 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Tue 1/5
6:00 am-1:41 pm
1 stop7h 41m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$277
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 1/28
6:00 am-7:38 pm
2 stops13h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$281
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Tue 1/5
7:40 pm-8:02 pm
2 stops24h 22m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$286
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Tue 1/5
3:00 pm-8:29 pm
3 stops53h 29m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$373
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 1/28
10:15 pm-7:45 pm
3 stops21h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$560
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 12/2
12:15 pm-5:12 pm
2 stops28h 57m
Panama City Tocumen Intl
Mon 12/7
10:00 am-11:59 pm
1 stop13h 59m
$631
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Mon 11/2
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Wed 11/4
10:00 am-11:59 pm
1 stop13h 59m
$651
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Sat 12/5
7:56 pm-8:02 pm
2 stops24h 06m
Panama City Tocumen Intl
Tue 12/15
11:35 am-11:03 am
2 stops23h 28m
$665
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 1/14
7:40 pm-8:02 pm
2 stops24h 22m
Panama City Tocumen Intl
Tue 1/19
4:41 pm-4:12 pm
1 stop23h 31m
$677
Sorted by cheapest first
Best time to book a flight from Charleston to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Charleston with our price prediction graph.
CHS-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama
CHS-PA0
CHS-PTY
What is the cheapest month to book a flight from Charleston to Panama?
Currently, March is the cheapest month in which you can book a flight from Charleston to Panama (average of $487). Flying from Charleston to Panama in November is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 30, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charleston to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Panama by cabin class
Find flights from Charleston to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Panama flights
Browse other Charleston and Panama flight options. Last updated on September 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charleston to Panama
Discover the top 3 airlines that operate flights from Charleston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$612 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$369 | Average$630 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$399 | Average$719 | FlexibilityNo cancel fee | On-time71% |