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$324+ Cheap flights from Charleston (CHS) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Jul 31 — Aug 71
Fri 7/31
Fri 8/7
1 adult, Economy
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Cheap flight deals from Charleston to Panama

Cheapest flights from Charleston to Panama
Explore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2026.

This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
CHS
-
PTY
1 stop13h 31m
United Airlines
Tue 9/229:45 am
PTY
-
CHS
1 stop13h 14m
United Airlines
Deal found 6/29$537
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:05 am
CHS
-
PTY
1 stop9h 26m
United Airlines
Sun 9/2710:00 am
PTY
-
CHS
1 stop11h 21m
United Airlines
Deal found 6/27$569
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:14 pm
CHS
-
PTY
2 stops15h 16m
Multiple Airlines
Sun 8/303:50 pm
PTY
-
CHS
2 stops17h 18m
Multiple Airlines
Deal found 7/1$570
This Expedia deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:25 pm
CHS
-
PTY
3 stops19h 30m
Multiple Airlines
Sun 8/303:50 pm
PTY
-
CHS
2 stops26h 45m
Multiple Airlines
Deal found 6/29$576
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:15 pm
CHS
-
PTY
1 stop13h 49m
United Airlines
Sun 8/303:30 pm
PTY
-
CHS
1 stop29h 41m
United Airlines
Deal found 7/1$580
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 am
CHS
-
PTY
1 stop8h 24m
United Airlines
Sun 8/233:30 pm
PTY
-
CHS
2 stops21h 28m
United Airlines
Deal found 6/29$585
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:50 am
CHS
-
PTY
1 stop10h 22m
United Airlines
Sat 7/257:55 am
PTY
-
CHS
1 stop13h 20m
United Airlines
Deal found 6/26$604
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:00 am
CHS
-
PTY
1 stop8h 14m
United Airlines
Sun 8/303:30 pm
PTY
-
CHS
2 stops18h 06m
United Airlines
Deal found 6/29$605
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:50 am
CHS
-
PTY
1 stop12h 47m
United Airlines
Wed 7/227:55 am
PTY
-
CHS
1 stop13h 20m
United Airlines
Deal found 6/26$607

Find flight deals from Charleston to Panama

Keep the following information in mind while searching for Charleston to Panama flight deals. Data was last updated July 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$537
(Delta)

One-way from

$324
(KAYAK)

Popular in

April

Cheapest in

August

Average price

$668
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
Search Deals
From Charleston to Panama
Search Deals
One-way flight from Charleston to Panama
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 9/3

11:10 am-4:04 am

1 stop17h 54m

Panama City Tocumen Intl

Mon 9/7

10:55 pm-9:13 am

1 stop9h 18m

$537

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 9/16

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Wed 9/23

9:45 am-11:59 pm

1 stop13h 14m

$537

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 10/15

6:00 am-7:31 pm

2 stops14h 31m

Panama City Tocumen Intl

Tue 10/20

9:45 am-11:59 pm

1 stop13h 14m

$541
Quickest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 9/24

11:05 am-7:31 pm

1 stop9h 26m

Panama City Tocumen Intl

Sun 9/27

10:00 am-10:21 pm

1 stop11h 21m

$569

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 8/27

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Sun 8/30

3:30 pm-1:58 pm

2 stops21h 28m

$573

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 10/1

6:00 am-7:31 pm

2 stops14h 31m

Panama City Tocumen Intl

Sat 10/10

3:30 pm-2:04 pm

2 stops21h 34m

$573

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 8/3

6:50 am-4:12 pm

1 stop10h 22m

Panama City Tocumen Intl

Sun 8/23

3:30 pm-10:11 pm

1 stop29h 41m

$592

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 7/20

6:50 am-4:12 pm

1 stop10h 22m

Panama City Tocumen Intl

Sat 7/25

7:55 am-10:15 pm

1 stop13h 20m

$604
Cheapest one-way
Quickest one-way

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 7/26

5:00 am-12:14 pm

2 stops8h 14m

$325

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 7/26

7:47 pm-12:35 am

3 stops29h 48m

$475

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Sorted by cheapest first

Best time to book a flight from Charleston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama

What is the cheapest month to book a flight from Charleston to Panama?

Currently, October is the cheapest month in which you can book a flight from Charleston to Panama (average of $309). Flying from Charleston to Panama in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 1, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charleston to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,452 reviews

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Comfort

7.8

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,452 reviews
Delta
7.8
Good
8,452 reviews

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Comfort

7.8

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,909 reviews
Delta
7.8
Good
8,452 reviews

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Comfort

7.8

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,766 reviews
Delta
7.8
Good
8,452 reviews

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Comfort

7.8

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Panama?

    For a flight from Charleston to Panama, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to Panama?

    United Airlines can get you from Charleston to Panama in just under 22h 34m. Your travel time can differ by up to . Airlines will cover a distance of 1645 mi.

  • Can I find deals for flights from Charleston to Panama that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama.

  • Can I find deals for business class flights from Charleston to Panama?

    Yes. Cheapflights offers flight deals from Charleston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama?

    Currently, October is the cheapest month in which you can book a flight from Charleston to Panama (average of $309). Flying from Charleston to Panama in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Charleston to Panama

Discover the top 3 airlines that operate flights from Charleston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$369Average$474FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$369Average$574FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$399Average$601FlexibilityNo cancel feeOn-time71%

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