$431+ Cheap flights from Panama City (PTY) to Cleveland (CLE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Cleveland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Cleveland
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Best
Last-minute
One-way
Cheapest flights from Panama City to ClevelandExplore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Faresmojo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:24 pm -
1 stop9h 33m
Tue 10/276:00 am -
1 stop7h 59m
Deal found 8/17![JetBlue logo]()
$594
This Faresmojo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:23 pm -
1 stop9h 16m
Wed 9/237:05 am -
1 stop6h 53m
Deal found 8/17![JetBlue logo]()
$646
This Faresmojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:30 pm -
1 stop18h 49m
Sat 1/307:40 pm -
1 stop18h 15m
Deal found 8/18![JetBlue logo]()
$658
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:02 pm -
2 stops21h 55m
Tue 10/276:43 pm -
2 stops19h 19m
Deal found 8/19![American Airlines logo]()
$734
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:15 pm -
2 stops16h 39m
Sat 1/309:19 pm -
2 stops18h 19m
Deal found 8/18![American Airlines logo]()
$742
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:30 pm -
1 stop18h 58m
Wed 11/41:55 pm -
1 stop30h 07m
Deal found 8/20![United Airlines logo]()
$752
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
1 stop19h 01m
Mon 10/58:00 am -
1 stop12h 31m
Deal found 8/17![United Airlines logo]()
$761
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:00 am -
1 stop24h 21m
Mon 9/286:10 am -
1 stop9h 04m
Deal found 8/20![United Airlines logo]()
$763
Best flights from Panama City to ClevelandDiscover carefully curated flight deals from Panama City to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Panama City to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Faresmojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:24 pm -
1 stop9h 33m
Tue 10/276:00 am -
1 stop7h 59m
Deal found 8/18![JetBlue logo]()
$594
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/14:41 pm -
1 stop24h 33m
Wed 3/316:15 am -
1 stop10h 57m
Deal found 8/18![United Airlines logo]()
$709
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:02 pm -
1 stop8h 57m
Tue 10/275:25 pm -
2 stops20h 37m
Deal found 8/19![American Airlines logo]()
$734
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1610:00 am -
1 stop9h 40m
Tue 2/236:15 am -
1 stop8h 30m
Deal found 8/20![United Airlines logo]()
$709
Last-minute flights from Panama City to ClevelandDiscover last-minute flight deals from Panama City to Cleveland. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Cleveland. Data last updated August 21, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:45 am -
1 stop11h 06m
Fri 9/185:20 pm -
1 stop27h 11m
Deal found 8/20![United Airlines logo]()
$827
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:30 pm -
1 stop18h 58m
Wed 11/41:55 pm -
1 stop30h 07m
Deal found 8/20![United Airlines logo]()
$752
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:16 pm -
1 stop9h 30m
Wed 11/45:38 pm -
2 stops20h 35m
Deal found 8/20![American Airlines logo]()
$771
This Faresmojo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:23 pm -
1 stop9h 16m
Wed 9/237:05 am -
1 stop6h 53m
Deal found 8/17![JetBlue logo]()
$646
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:16 pm -
2 stops18h 44m
Wed 9/238:49 pm -
2 stops16h 27m
Deal found 8/19![American Airlines logo]()
$782
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:00 am -
1 stop24h 21m
Mon 9/286:10 am -
1 stop9h 04m
Deal found 8/20![United Airlines logo]()
$763
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:16 pm -
1 stop9h 30m
Mon 9/287:40 pm -
2 stops17h 46m
Deal found 8/20![American Airlines logo]()
$766
One-way flights from Panama City to ClevelandSearch for one-way flight options from Panama City to Cleveland. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Panama City to Cleveland. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:45 am -
1 stop11h 06m
Deal found 8/20![United Airlines logo]()
$431
This deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:20 pm -
1 stop9h 09m
Deal found 8/20![Delta logo]()
$441
Find flight deals from Panama City to Cleveland
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $594 (Faresmojo) |
One-way from | $420 (Delta) |
Popular in | March |
Cheapest in | February |
Average price | $700 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Fri 10/16
2:24 pm-12:57 am
1 stop9h 33m
Cleveland Hopkins Intl
Tue 10/27
6:00 am-12:59 pm
1 stop7h 59m
$594
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Mon 2/1
4:41 pm-5:14 pm
1 stop24h 33m
Cleveland Hopkins Intl
Wed 3/31
6:15 am-4:12 pm
1 stop10h 57m
$709
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Tue 2/16
10:00 am-7:40 pm
1 stop9h 40m
Cleveland Hopkins Intl
Tue 2/23
6:15 am-2:45 pm
1 stop8h 30m
$709
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Fri 10/16
2:02 pm-11:59 pm
1 stop8h 57m
Cleveland Hopkins Intl
Tue 10/27
5:25 pm-1:02 pm
2 stops20h 37m
$734
Cheapest one-way
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Thu 9/3
9:45 am-9:51 pm
1 stop11h 06m
$431
Quickest one-way
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Fri 9/4
2:20 pm-12:29 am
1 stop9h 09m
$441
Sorted by cheapest first
Compare providers for flights from Panama City to Cleveland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cleveland in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Cleveland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Cleveland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Cleveland flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Cleveland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Cleveland
Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama City with our price prediction graph.
PTY-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Cleveland
Reviews of airlines servicing Cleveland
Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated August 21, 2026.
Read through reviews of airlines operating flights from Panama City to Cleveland, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Crew
8.1
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Food
6.7
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Crew
8.1
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama City to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cleveland?
Book flights to Cleveland if you plan to visit one of these locationsSandusky
Beachwood
Independence
Mansfield
Strongsville
Lakewood
Avon
Streetsboro
Medina
North Olmsted
Cuyahoga Falls
Macedonia
Kent
Westlake
Elyria
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Cleveland
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Other flights to Cleveland
Explore flights to Cleveland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Complete your trip
Complete your trip to Cleveland by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama City to Cleveland, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Cleveland flights
Browse other Panama City and Cleveland flight options. Last updated on August 21, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Cleveland
Discover the top airline that operate flights from Panama City to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$644 | Average$718 | FlexibilityNo cancel fee | On-time69% |