$344+ Cheap flights from Syracuse (SYR) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Sep 16 — Sep 231
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Syracuse to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Syracuse to Panama CityExplore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:53 pm -
2 stops23h 44m
Mon 10/53:30 pm -
2 stops19h 23m
Deal found 8/14![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am -
1 stop7h 48m
Tue 9/222:23 pm -
1 stop8h 35m
Deal found 8/17![Delta logo]()
$753
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am -
2 stops14h 21m
Tue 9/223:30 pm -
2 stops24h 22m
Deal found 8/17![United Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:55 pm -
2 stops19h 19m
Sat 9/193:30 pm -
2 stops28h 29m
Deal found 8/14![United Airlines logo]()
$787
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:44 pm -
2 stops17h 32m
Sun 10/41:16 pm -
2 stops21h 11m
Deal found 8/13![American Airlines logo]()
$789
This Ovago deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops14h 02m
Wed 11/118:55 am -
2 stops12h 31m
Deal found 8/17![Copa Airlines logo]()
$797
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops37h 55m
Wed 11/1111:25 am -
3 stops36h 29m
Deal found 8/17![Multiple Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:10 am -
1 stop7h 48m
Sat 9/192:23 pm -
1 stop8h 35m
Deal found 8/14![Delta logo]()
$813
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:44 pm -
2 stops17h 32m
Sat 9/191:16 pm -
2 stops21h 19m
Deal found 8/13![American Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:55 pm -
2 stops24h 36m
Wed 9/23:30 pm -
2 stops18h 06m
Deal found 8/16![United Airlines logo]()
$837
Best flights from Syracuse to Panama CityDiscover carefully curated flight deals from Syracuse to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from Syracuse to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:53 pm -
2 stops23h 44m
Mon 10/53:30 pm -
2 stops19h 23m
Deal found 8/14![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am -
1 stop7h 48m
Tue 9/222:23 pm -
1 stop8h 35m
Deal found 8/17![Delta logo]()
$753
This Ovago deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops14h 02m
Wed 11/118:55 am -
2 stops12h 31m
Deal found 8/17![Copa Airlines logo]()
$797
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:44 pm -
2 stops17h 32m
Sat 9/191:16 pm -
2 stops21h 19m
Deal found 8/15![American Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/65:33 pm -
2 stops26h 29m
Wed 2/104:41 pm -
2 stops17h 21m
Deal found 8/16![United Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:10 am -
1 stop7h 48m
Sat 9/192:23 pm -
1 stop8h 35m
Deal found 8/16![Delta logo]()
$813
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:55 pm -
2 stops19h 19m
Sat 9/193:30 pm -
2 stops28h 29m
Deal found 8/14![United Airlines logo]()
$787
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am -
2 stops14h 31m
Sun 10/43:30 pm -
2 stops19h 23m
Deal found 8/13![United Airlines logo]()
$817
Last-minute flights from Syracuse to Panama CityDiscover last-minute flight deals from Syracuse to Panama City. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Panama City. Data last updated August 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:55 pm -
2 stops24h 36m
Wed 9/23:30 pm -
2 stops18h 06m
Deal found 8/16![United Airlines logo]()
$837
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am -
2 stops14h 51m
Wed 9/212:03 pm -
1 stop21h 01m
Deal found 8/16![Multiple Airlines logo]()
$1,353
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:55 pm -
2 stops19h 19m
Sat 9/193:30 pm -
2 stops28h 29m
Deal found 8/14![United Airlines logo]()
$787
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:10 am -
1 stop7h 48m
Sat 9/192:23 pm -
1 stop8h 35m
Deal found 8/14![Delta logo]()
$813
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:44 pm -
2 stops17h 32m
Sat 9/191:16 pm -
2 stops21h 19m
Deal found 8/13![American Airlines logo]()
$817
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:29 pm -
1 stop13h 10m
Sat 9/1910:00 am -
2 stops31h 49m
Deal found 8/14![Multiple Airlines logo]()
$1,420
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am -
1 stop7h 48m
Tue 9/222:23 pm -
1 stop8h 35m
Deal found 8/17![Delta logo]()
$753
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am -
2 stops14h 21m
Tue 9/223:30 pm -
2 stops24h 22m
Deal found 8/17![United Airlines logo]()
$757
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:44 pm -
2 stops17h 32m
Sun 10/41:16 pm -
2 stops21h 11m
Deal found 8/13![American Airlines logo]()
$789
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:29 pm -
1 stop13h 10m
Sun 10/44:25 am -
2 stops13h 24m
Deal found 8/13![Multiple Airlines logo]()
$1,659
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:53 pm -
2 stops23h 44m
Mon 10/53:30 pm -
2 stops19h 23m
Deal found 8/14![United Airlines logo]()
$737
One-way flights from Syracuse to Panama CitySearch for one-way flight options from Syracuse to Panama City. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from Syracuse to Panama City. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop7h 59m
Deal found 8/14![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:23 pm -
2 stops20h 16m
Deal found 8/17![American Airlines logo]()
$364
This Expedia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
3 stops33h 55m
Deal found 8/14![Multiple Airlines logo]()
$379
This KAYAK deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:55 pm -
1 stop11h 18m
Deal found 8/17![Copa Airlines logo]()
$954
Find flight deals from Syracuse to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $737 (United Airlines) |
One-way from | $344 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Mon 9/28
7:53 pm-6:37 pm
2 stops23h 44m
Panama City Tocumen Intl
Mon 10/5
3:30 pm-11:53 am
2 stops19h 23m
$737
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sat 2/6
5:33 pm-8:02 pm
2 stops26h 29m
Panama City Tocumen Intl
Wed 2/10
4:41 pm-10:02 am
2 stops17h 21m
$747
Quickest round-trip
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Wed 9/16
6:10 am-12:58 pm
1 stop7h 48m
Panama City Tocumen Intl
Tue 9/22
2:23 pm-11:58 pm
1 stop8h 35m
$753
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sun 9/13
7:55 pm-2:14 pm
2 stops19h 19m
Panama City Tocumen Intl
Sat 9/19
3:30 pm-8:59 pm
2 stops28h 29m
$787
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sat 10/31
6:00 am-7:02 pm
2 stops14h 02m
Panama City Tocumen Intl
Wed 11/11
8:55 am-9:26 pm
2 stops12h 31m
$797
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sun 9/13
6:10 am-12:58 pm
1 stop7h 48m
Panama City Tocumen Intl
Sat 9/19
2:23 pm-11:58 pm
1 stop8h 35m
$813
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sun 9/13
7:44 pm-12:16 pm
2 stops17h 32m
Panama City Tocumen Intl
Sat 9/19
1:16 pm-11:35 am
2 stops21h 19m
$817
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sun 9/27
6:00 am-7:31 pm
2 stops14h 31m
Panama City Tocumen Intl
Sun 10/4
3:30 pm-11:53 am
2 stops19h 23m
$817
Cheapest one-way
Quickest one-way
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Wed 10/28
6:00 am-12:59 pm
1 stop7h 59m
$344
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Wed 10/28
6:07 am-6:38 pm
2 stops13h 31m
$344
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Syracuse to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Panama City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
SYR-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 17, 2026.
Read reviews from past customers who have flown Delta from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Syracuse
Panama City flight routes
Popular flights
Alternative routes for Syracuse to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Syracuse to Panama City by cabin class
Find flights from Syracuse to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Syracuse and Panama City flights
Browse other Syracuse and Panama City flight options. Last updated on August 17, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Syracuse to Panama City
Discover the top airline that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$517 | Average$948 | FlexibilityNo cancel fee | On-timeN/A |