$631+ Cheap flights from Syracuse (SYR) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Nov 1 — Nov 81
Round-trip
1 adult, Economy
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Find cheap flights from Syracuse to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Panama City
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Best
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Cheapest flights from Syracuse to Panama CityExplore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:50 pm -
2 stops24h 12m
Mon 12/711:35 am -
2 stops23h 13m
Deal found 9/29![United Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:56 pm -
2 stops21h 17m
Mon 11/233:34 pm -
2 stops19h 12m
Deal found 10/2![American Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:50 pm -
2 stops23h 48m
Sat 12/510:00 am -
2 stops24h 48m
Deal found 10/1![United Airlines logo]()
$730
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:30 pm -
2 stops19h 32m
Wed 10/142:02 pm -
2 stops19h 59m
Deal found 9/29![American Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:50 pm -
2 stops18h 55m
Mon 12/144:41 pm -
2 stops18h 07m
Deal found 9/27![United Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:37 pm -
2 stops19h 57m
Mon 12/73:13 pm -
2 stops25h 11m
Deal found 9/28![American Airlines logo]()
$779
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:20 pm -
2 stops21h 25m
Sat 11/2110:00 am -
2 stops24h 45m
Deal found 9/30![United Airlines logo]()
$789
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops24h 27m
Fri 11/204:41 pm -
2 stops28h 36m
Deal found 9/29![United Airlines logo]()
$804
Best flights from Syracuse to Panama CityDiscover carefully curated flight deals from Syracuse to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
Discover carefully curated flight deals from Syracuse to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:50 pm -
2 stops24h 12m
Mon 12/711:35 am -
2 stops23h 13m
Deal found 9/29![United Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:54 pm -
2 stops21h 40m
Mon 12/73:13 pm -
2 stops19h 42m
Deal found 10/1![American Airlines logo]()
$780
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop8h 02m
Mon 11/233:29 pm -
1 stop8h 30m
Deal found 10/2![Delta logo]()
$930
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:50 pm -
2 stops24h 12m
Sat 12/511:35 am -
2 stops23h 13m
Deal found 10/2![United Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:50 pm -
2 stops18h 55m
Mon 12/144:41 pm -
2 stops18h 07m
Deal found 9/27![United Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 pm -
2 stops18h 43m
Sat 12/53:13 pm -
1 stop8h 42m
Deal found 10/2![American Airlines logo]()
$882
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:20 pm -
2 stops21h 25m
Sat 11/2110:00 am -
2 stops24h 45m
Deal found 9/30![United Airlines logo]()
$789
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops24h 27m
Fri 11/204:41 pm -
2 stops28h 36m
Deal found 9/29![United Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:35 pm -
2 stops24h 27m
Fri 11/610:00 am -
2 stops24h 30m
Deal found 9/30![United Airlines logo]()
$1,047
Last-minute flights from Syracuse to Panama CityDiscover last-minute flight deals from Syracuse to Panama City. Data last updated October 2, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Panama City. Data last updated October 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:30 pm -
2 stops19h 32m
Wed 10/142:02 pm -
2 stops19h 59m
Deal found 9/29![American Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:35 pm -
2 stops24h 27m
Fri 11/610:00 am -
2 stops24h 30m
Deal found 9/29![United Airlines logo]()
$1,047
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:55 pm -
2 stops29h 07m
Thu 11/198:55 am -
2 stops14h 48m
Deal found 9/28![United Airlines logo]()
$839
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops24h 27m
Fri 11/204:41 pm -
2 stops28h 36m
Deal found 9/29![United Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:20 pm -
2 stops21h 25m
Sat 11/2110:00 am -
2 stops24h 45m
Deal found 9/30![United Airlines logo]()
$789
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:56 pm -
2 stops21h 17m
Mon 11/233:34 pm -
2 stops19h 12m
Deal found 10/2![American Airlines logo]()
$711
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop8h 02m
Mon 11/233:29 pm -
1 stop8h 30m
Deal found 10/2![Delta logo]()
$930
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:37 pm -
2 stops19h 57m
Mon 12/73:13 pm -
2 stops25h 11m
Deal found 9/28![American Airlines logo]()
$779
Find flight deals from Syracuse to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $631 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Tue 12/1
7:50 pm-8:02 pm
2 stops24h 12m
Panama City Tocumen Intl
Mon 12/7
11:35 am-10:48 am
2 stops23h 13m
$631
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Tue 12/1
7:50 pm-8:02 pm
2 stops24h 12m
Panama City Tocumen Intl
Sat 12/5
11:35 am-10:48 am
2 stops23h 13m
$730
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sat 12/12
7:50 pm-2:45 pm
2 stops18h 55m
Panama City Tocumen Intl
Mon 12/14
4:41 pm-10:48 am
2 stops18h 07m
$775
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Mon 11/30
4:54 pm-2:34 pm
2 stops21h 40m
Panama City Tocumen Intl
Mon 12/7
3:13 pm-10:55 am
2 stops19h 42m
$780
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sat 11/14
5:20 pm-2:45 pm
2 stops21h 25m
Panama City Tocumen Intl
Sat 11/21
10:00 am-10:45 am
2 stops24h 45m
$789
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Fri 11/13
7:35 pm-8:02 pm
2 stops24h 27m
Panama City Tocumen Intl
Fri 11/20
4:41 pm-9:17 pm
2 stops28h 36m
$804
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Tue 12/1
7:30 pm-2:13 pm
2 stops18h 43m
Panama City Tocumen Intl
Sat 12/5
3:13 pm-11:55 pm
1 stop8h 42m
$882
Quickest round-trip
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Mon 11/16
6:00 am-2:02 pm
1 stop8h 02m
Panama City Tocumen Intl
Mon 11/23
3:29 pm-11:59 pm
1 stop8h 30m
$930
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Tue 11/3
7:35 pm-8:02 pm
2 stops24h 27m
Panama City Tocumen Intl
Fri 11/6
10:00 am-10:30 am
2 stops24h 30m
$1,047
Sorted by cheapest first
Compare providers for flights from Syracuse to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
SYR-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 2, 2026.
Read reviews from past customers who have flown Delta from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Syracuse and Panama City flights
Browse other Syracuse and Panama City flight options. Last updated on October 2, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on October 2, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Syracuse to Panama City
Discover the top airline that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$517 | Average$854 | FlexibilityNo cancel fee | On-timeN/A |