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Panama City

$310+ Cheap flights from Buffalo (BUF) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Jul 19 — Jul 261
Sun 7/19
Sun 7/26
1 adult, Economy
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Cheap flight deals from Buffalo to Panama City

Cheapest flights from Buffalo to Panama City
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.

This Expedia deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:02 pm
BUF
-
PTY
2 stops15h 28m
Multiple Airlines
Sat 8/223:50 pm
PTY
-
BUF
2 stops15h 00m
Multiple Airlines
Deal found 6/18$570
This Expedia deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:00 pm
BUF
-
PTY
2 stops22h 55m
Multiple Airlines
Wed 11/257:50 pm
PTY
-
BUF
2 stops13h 09m
Multiple Airlines
Deal found 6/17$605
This Expedia deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:32 pm
BUF
-
PTY
2 stops19h 58m
Multiple Airlines
Sun 7/55:30 am
PTY
-
BUF
2 stops25h 25m
Multiple Airlines
Deal found 6/17$666
This Travelocity deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:21 pm
BUF
-
PTY
2 stops31h 34m
Multiple Airlines
Mon 8/33:50 pm
PTY
-
BUF
2 stops22h 09m
Multiple Airlines
Deal found 6/16$668
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
BUF
-
PTY
2 stops14h 31m
United Airlines
Thu 10/19:45 am
PTY
-
BUF
2 stops22h 44m
United Airlines
Deal found 6/14$677
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:55 am
BUF
-
PTY
2 stops12h 42m
United Airlines
Sat 8/223:30 pm
PTY
-
BUF
2 stops16h 58m
United Airlines
Deal found 6/16$707
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
BUF
-
PTY
1 stop14h 31m
United Airlines
Mon 8/310:55 pm
PTY
-
BUF
1 stop9h 58m
United Airlines
Deal found 6/15$713

Find flight deals from Buffalo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$570
(Expedia)

One-way from

$310
(Expedia)
Provider with most accurate pricing for Buffalo-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Panama City Tocumen Intl flights.
Search Deals
From Buffalo to Panama City Tocumen Intl
Search Deals
One-way flight from Buffalo to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 7/31

7:21 pm-1:55 am

2 stops31h 34m

Panama City Tocumen Intl

Mon 8/3

3:50 pm-2:59 pm

2 stops22h 09m

$668
Quickest round-trip

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 7/30

6:00 am-7:31 pm

1 stop14h 31m

Panama City Tocumen Intl

Mon 8/3

10:55 pm-9:53 am

1 stop9h 58m

$713

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 11/13

7:40 pm-2:05 pm

1 stop18h 25m

Panama City Tocumen Intl

Wed 11/25

3:30 pm-11:55 pm

1 stop8h 25m

$713

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/17

6:00 am-4:04 am

1 stop23h 04m

Panama City Tocumen Intl

Sat 8/22

3:30 pm-9:28 am

2 stops16h 58m

$715

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 11/13

11:40 am-8:02 pm

1 stop8h 22m

Panama City Tocumen Intl

Wed 11/25

4:41 pm-3:16 pm

2 stops22h 35m

$717

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 7/31

6:15 am-6:37 pm

2 stops13h 22m

Panama City Tocumen Intl

Mon 8/3

7:55 am-10:59 pm

2 stops14h 04m

$730
Cheapest one-way

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 7/18

8:01 pm-10:30 am

2 stops15h 29m

$310
Quickest one-way

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 7/31

6:15 am-6:37 pm

2 stops13h 22m

$337

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 7/18

6:00 am-7:31 pm

1 stop14h 31m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/18

Sorted by cheapest first

Compare providers for flights from Buffalo to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated June 19, 2026.
Read through reviews of airlines operating flights from Buffalo to Panama City, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,417 reviews

Boarding

8.1

Entertainment

7.8

Overall

7.8

Food

7.2

Crew

8.5

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
Delta
7.8
Good
8,417 reviews
Delta
7.8
Good
8,417 reviews

Boarding

8.1

Entertainment

7.8

Overall

7.8

Food

7.2

Crew

8.5

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Panama City?

    United Airlines and Delta can get you from Buffalo to Panama City in just under 14h 31m. Your travel time can differ by up to 3h 54m. Airlines will cover a distance of 2339 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Buffalo to Panama City round-trip?

    Delta, at $517, was found to be the cheapest airline from Buffalo to Panama City..

  • Can I find deals for flights from Buffalo to Panama City that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama City.

  • Can I find deals for business class flights from Buffalo to Panama City?

    Yes. Cheapflights offers flight deals from Buffalo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Buffalo to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Panama City flights
Newark to Panama City flights
Syracuse to Panama City flights
Rochester to Panama City flights
Ithaca to Panama City flights

Top airline flying from Buffalo to Panama City

Discover the top airline that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$517Average$685FlexibilityNo cancel feeOn-timeN/A

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