$262+ Cheap flights from Buffalo (BUF) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Aug 9 — Aug 161
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
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Cheapest flights from Buffalo to PanamaExplore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This SmartFares deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:00 pm
BUF
- PTY
2 stops15h 30m
Multiple Airlines
Tue 10/203:50 pm
PTY
- BUF
2 stops15h 34m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$555
This Expedia deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:55 pm
BUF
- PTY
2 stops19h 35m
Multiple Airlines
Tue 8/253:50 pm
PTY
- BUF
2 stops15h 02m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$570
This Expedia deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:02 pm
BUF
- PTY
3 stops19h 53m
Multiple Airlines
Sat 8/293:50 pm
PTY
- BUF
2 stops15h 02m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$576
This Expedia deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:00 pm
BUF
- PTY
2 stops15h 30m
Multiple Airlines
Wed 10/287:50 pm
PTY
- BUF
2 stops19h 29m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$611
This SmartFares deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:15 am
BUF
- PTY
2 stops26h 15m
Multiple Airlines
Thu 7/163:50 pm
PTY
- BUF
2 stops15h 02m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$625
This Orbitz deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:06 pm
BUF
- PTY
2 stops39h 24m
Multiple Airlines
Sat 8/83:50 pm
PTY
- BUF
2 stops26h 20m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$635
This Expedia deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:21 pm
BUF
- PTY
2 stops16h 09m
Multiple Airlines
Mon 8/103:50 pm
PTY
- BUF
2 stops22h 09m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$656
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:16 pm
BUF
- PTY
1 stop25h 39m
Delta
Wed 9/92:23 pm
PTY
- BUF
1 stop8h 31m
Delta
Deal found 7/6![Delta logo]()
$663
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
BUF
- PTY
1 stop7h 56m
Delta
Mon 10/192:21 pm
PTY
- BUF
1 stop19h 55m
Delta
Deal found 7/7![Delta logo]()
$664
This Expedia deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:06 pm
BUF
- PTY
2 stops39h 24m
Multiple Airlines
Fri 8/711:25 am
PTY
- BUF
3 stops19h 27m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$670
This Travelocity deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:02 pm
BUF
- PTY
2 stops30h 53m
Multiple Airlines
Fri 9/43:50 pm
PTY
- BUF
2 stops22h 09m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$673
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:43 pm
BUF
- PTY
2 stops18h 13m
Delta
Tue 10/202:21 pm
PTY
- BUF
2 stops19h 55m
Delta
Deal found 7/7![Delta logo]()
$677
Best flights from Buffalo to PanamaDiscover carefully curated flight deals from Buffalo to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from Buffalo to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This Expedia deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:00 pm
BUF
- PTY
2 stops15h 30m
Multiple Airlines
Wed 10/2811:25 am
PTY
- BUF
3 stops20h 02m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:13 pm
BUF
- PTY
1 stop20h 42m
Delta
Thu 9/102:23 pm
PTY
- BUF
1 stop8h 31m
Delta
Deal found 7/6![Delta logo]()
$663
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:33 pm
BUF
- PTY
1 stop9h 31m
United Airlines
Tue 8/253:30 pm
PTY
- BUF
2 stops20h 46m
United Airlines
Deal found 7/6![United Airlines logo]()
$697
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:05 am
BUF
- PTY
1 stop7h 50m
Delta
Tue 8/252:20 pm
PTY
- BUF
1 stop8h 39m
Delta
Deal found 7/6![Delta logo]()
$713
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:34 am
BUF
- PTY
1 stop18h 30m
United Airlines
Wed 9/169:45 am
PTY
- BUF
1 stop12h 27m
United Airlines
Deal found 7/8![United Airlines logo]()
$713
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am
BUF
- PTY
2 stops13h 37m
United Airlines
Wed 8/2610:55 pm
PTY
- BUF
2 stops17h 01m
United Airlines
Deal found 7/6![United Airlines logo]()
$717
Last-minute flights from Buffalo to PanamaDiscover last-minute flight deals from Buffalo to Panama. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Panama. Data last updated July 10, 2026 and is based on user searches.
This SmartFares deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:15 am
BUF
- PTY
2 stops26h 15m
Multiple Airlines
Thu 7/163:50 pm
PTY
- BUF
2 stops15h 02m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:34 am
BUF
- PTY
1 stop18h 30m
United Airlines
Wed 9/169:45 am
PTY
- BUF
1 stop12h 27m
United Airlines
Deal found 7/8![United Airlines logo]()
$713
This FlightHub deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:21 pm
BUF
- PTY
3 stops20h 34m
Multiple Airlines
Wed 9/2311:25 am
PTY
- BUF
3 stops19h 59m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$710
This Orbitz deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:06 pm
BUF
- PTY
2 stops39h 24m
Multiple Airlines
Sat 8/83:50 pm
PTY
- BUF
2 stops26h 20m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$635
This Expedia deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:06 pm
BUF
- PTY
2 stops39h 24m
Multiple Airlines
Fri 8/711:25 am
PTY
- BUF
3 stops19h 27m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$670
This Expedia deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:21 pm
BUF
- PTY
2 stops16h 09m
Multiple Airlines
Mon 8/103:50 pm
PTY
- BUF
2 stops22h 09m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$656
This Travelocity deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:02 pm
BUF
- PTY
2 stops30h 53m
Multiple Airlines
Fri 9/43:50 pm
PTY
- BUF
2 stops22h 09m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$673
This Expedia deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:55 pm
BUF
- PTY
2 stops19h 35m
Multiple Airlines
Tue 8/253:50 pm
PTY
- BUF
2 stops15h 02m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
BUF
- PTY
1 stop14h 31m
United Airlines
Wed 8/2610:00 am
PTY
- BUF
2 stops22h 28m
United Airlines
Deal found 7/5![United Airlines logo]()
$697
This Expedia deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:02 pm
BUF
- PTY
3 stops19h 53m
Multiple Airlines
Sat 8/293:50 pm
PTY
- BUF
2 stops15h 02m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:48 pm
BUF
- PTY
2 stops18h 07m
Delta
Thu 9/102:23 pm
PTY
- BUF
2 stops17h 01m
Delta
Deal found 7/6![Delta logo]()
$663
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:16 pm
BUF
- PTY
1 stop25h 39m
Delta
Fri 9/42:20 pm
PTY
- BUF
2 stops20h 02m
Delta
Deal found 7/6![Delta logo]()
$693
One-way flights from Buffalo to PanamaSearch for one-way flight options from Buffalo to Panama. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
Search for one-way flight options from Buffalo to Panama. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
This Expedia deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:32 pm
BUF
- PTY
2 stops19h 58m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$262
This FlightHub deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:10 pm
BUF
- PTY
3 stops20h 45m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$307
This Expedia deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:40 am
BUF
- PTY
2 stops44h 15m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$312
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
BUF
- PTY
1 stop14h 31m
United Airlines
Deal found 7/9![United Airlines logo]()
$320
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:34 am
BUF
- PTY
1 stop18h 30m
United Airlines
Deal found 7/9![United Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:52 pm
BUF
- PTY
2 stops21h 20m
United Airlines
Deal found 7/9![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
BUF
- PTY
1 stop14h 31m
United Airlines
Deal found 7/9![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:04 pm
BUF
- PTY
2 stops23h 08m
United Airlines
Deal found 7/9![United Airlines logo]()
$352
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
BUF
- PTY
1 stop23h 04m
United Airlines
Deal found 7/9![United Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:29 am
BUF
- PTY
3 stops44h 22m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
BUF
- PTY
1 stop14h 31m
United Airlines
Deal found 7/9![United Airlines logo]()
$412
Find flight deals from Buffalo to Panama
Keep the following information in mind while searching for Buffalo to Panama flight deals. Data was last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $555 (SmartFares) |
One-way from | $307 (FlightHub) |
Popular in | January |
Cheapest in | October |
Average price | $844 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Buffalo to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 10/20
8:00 pm-10:30 am
2 stops15h 30m
Panama City Tocumen Intl
Wed 10/28
11:25 am-8:27 am
3 stops20h 02m
$576
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 9/1
5:13 pm-12:55 pm
1 stop20h 42m
Panama City Tocumen Intl
Thu 9/10
2:23 pm-11:54 pm
1 stop8h 31m
$663
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 8/18
7:33 pm-4:04 am
1 stop9h 31m
Panama City Tocumen Intl
Tue 8/25
3:30 pm-1:16 pm
2 stops20h 46m
$697
Quickest round-trip
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 8/18
6:05 am-12:55 pm
1 stop7h 50m
Panama City Tocumen Intl
Tue 8/25
2:20 pm-11:59 pm
1 stop8h 39m
$713
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Wed 7/22
10:34 am-4:04 am
1 stop18h 30m
Panama City Tocumen Intl
Wed 9/16
9:45 am-11:12 pm
1 stop12h 27m
$713
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 8/25
6:00 am-6:37 pm
2 stops13h 37m
Panama City Tocumen Intl
Wed 8/26
10:55 pm-4:56 pm
2 stops17h 01m
$717
Cheapest one-way
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Mon 8/24
3:32 pm-10:30 am
2 stops19h 58m
$262
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Mon 8/24
6:00 am-7:31 pm
1 stop14h 31m
$320
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Thu 8/6
10:34 am-4:04 am
1 stop18h 30m
$324
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Wed 8/5
7:52 pm-4:12 pm
2 stops21h 20m
$344
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Buffalo to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Buffalo with our price prediction graph.
BUF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Panama
BUF-PA0
BUF-PTY
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 10, 2026.
Read through reviews of airlines operating flights from Buffalo to Panama, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Buffalo to Panama
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to Panama by cabin class
Find flights from Buffalo to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and Panama flights
Browse other Buffalo and Panama flight options. Last updated on July 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Buffalo to Panama
Discover the top airline that operate flights from Buffalo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$517 | Average$732 | FlexibilityNo cancel fee | On-timeN/A |