$249+ Cheap flights from Buffalo (BUF) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
May 12 — May 191
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
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Cheapest flights from Buffalo to PanamaExplore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
Explore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
This Expedia deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:00 pm
BUF
- PTY
2 stops15h 30m
Multiple Airlines
Wed 6/33:50 pm
PTY
- BUF
2 stops16h 08m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$570
This Expedia deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:41 pm
BUF
- PTY
3 stops25h 14m
Multiple Airlines
Wed 6/311:25 am
PTY
- BUF
3 stops20h 33m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 am
BUF
- PTY
1 stop7h 35m
Delta
Wed 6/102:24 pm
PTY
- BUF
1 stop8h 35m
Delta
Deal found 4/10![Delta logo]()
$623
This Expedia deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:05 am
BUF
- PTY
2 stops29h 25m
Multiple Airlines
Sat 5/305:30 am
PTY
- BUF
2 stops26h 28m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:50 pm
BUF
- PTY
2 stops21h 24m
United Airlines
Wed 10/213:20 pm
PTY
- BUF
2 stops17h 29m
United Airlines
Deal found 4/7![United Airlines logo]()
$647
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:04 pm
BUF
- PTY
2 stops22h 42m
American Airlines
Sat 5/231:14 pm
PTY
- BUF
2 stops21h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$653
This Expedia deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:01 pm
BUF
- PTY
2 stops15h 29m
Multiple Airlines
Mon 5/113:50 pm
PTY
- BUF
2 stops21h 06m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:52 pm
BUF
- PTY
2 stops21h 22m
United Airlines
Mon 7/1310:55 pm
PTY
- BUF
2 stops20h 46m
United Airlines
Deal found 4/9![United Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:52 pm
BUF
- PTY
2 stops24h 39m
United Airlines
Wed 6/107:55 am
PTY
- BUF
2 stops12h 08m
United Airlines
Deal found 4/10![United Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 am
BUF
- PTY
1 stop7h 35m
Delta
Wed 6/32:15 pm
PTY
- BUF
1 stop8h 44m
Delta
Deal found 4/10![Delta logo]()
$663
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:36 am
BUF
- PTY
1 stop9h 58m
Multiple Airlines
Wed 6/109:33 pm
PTY
- BUF
2 stops39h 22m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$665
Best flights from Buffalo to PanamaDiscover carefully curated flight deals from Buffalo to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
Discover carefully curated flight deals from Buffalo to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 am
BUF
- PTY
1 stop7h 35m
Delta
Wed 6/102:24 pm
PTY
- BUF
1 stop8h 35m
Delta
Deal found 4/12![Delta logo]()
$623
This Expedia deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:05 am
BUF
- PTY
2 stops29h 25m
Multiple Airlines
Sat 5/305:30 am
PTY
- BUF
2 stops26h 28m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:04 pm
BUF
- PTY
2 stops22h 42m
American Airlines
Sat 5/231:14 pm
PTY
- BUF
2 stops21h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:00 pm
BUF
- PTY
1 stop10h 04m
United Airlines
Mon 7/1310:55 pm
PTY
- BUF
2 stops20h 46m
United Airlines
Deal found 4/9![United Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:34 am
BUF
- PTY
1 stop9h 57m
United Airlines
Wed 6/37:55 am
PTY
- BUF
2 stops24h 56m
United Airlines
Deal found 4/12![United Airlines logo]()
$660
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 am
BUF
- PTY
1 stop7h 35m
Delta
Wed 6/32:15 pm
PTY
- BUF
1 stop8h 44m
Delta
Deal found 4/11![Delta logo]()
$663
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:52 pm
BUF
- PTY
2 stops24h 39m
United Airlines
Wed 6/107:55 am
PTY
- BUF
2 stops12h 08m
United Airlines
Deal found 4/10![United Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
BUF
- PTY
1 stop8h 02m
Delta
Mon 5/112:15 pm
PTY
- BUF
1 stop8h 44m
Delta
Deal found 4/9![Delta logo]()
$666
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
BUF
- PTY
2 stops12h 37m
United Airlines
Sat 5/167:55 am
PTY
- BUF
2 stops24h 58m
United Airlines
Deal found 4/12![United Airlines logo]()
$673
Last-minute flights from Buffalo to PanamaDiscover last-minute flight deals from Buffalo to Panama. Data last updated April 12, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Panama. Data last updated April 12, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:01 pm
BUF
- PTY
2 stops15h 29m
Multiple Airlines
Mon 5/113:50 pm
PTY
- BUF
2 stops21h 06m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$656
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
BUF
- PTY
1 stop8h 02m
Delta
Mon 5/112:15 pm
PTY
- BUF
1 stop8h 44m
Delta
Deal found 4/10![Delta logo]()
$666
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
BUF
- PTY
2 stops13h 31m
United Airlines
Mon 5/113:30 pm
PTY
- BUF
2 stops17h 11m
United Airlines
Deal found 4/10![United Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:04 pm
BUF
- PTY
2 stops22h 42m
American Airlines
Sat 5/231:14 pm
PTY
- BUF
2 stops21h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$653
This Expedia deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:05 am
BUF
- PTY
2 stops29h 25m
Multiple Airlines
Sat 5/305:30 am
PTY
- BUF
2 stops26h 28m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$635
This Expedia deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:00 pm
BUF
- PTY
2 stops15h 30m
Multiple Airlines
Wed 6/33:50 pm
PTY
- BUF
2 stops16h 08m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:46 pm
BUF
- PTY
2 stops20h 28m
American Airlines
Wed 6/31:14 pm
PTY
- BUF
2 stops20h 19m
American Airlines
Deal found 4/10![American Airlines logo]()
$647
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 am
BUF
- PTY
1 stop7h 35m
Delta
Wed 6/32:15 pm
PTY
- BUF
1 stop8h 44m
Delta
Deal found 4/10![Delta logo]()
$663
This Expedia deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:41 pm
BUF
- PTY
3 stops25h 14m
Multiple Airlines
Wed 6/311:25 am
PTY
- BUF
3 stops20h 33m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$601
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:34 am
BUF
- PTY
1 stop9h 57m
United Airlines
Wed 6/37:55 am
PTY
- BUF
2 stops24h 56m
United Airlines
Deal found 4/12![United Airlines logo]()
$660
One-way flights from Buffalo to PanamaSearch for one-way flight options from Buffalo to Panama. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
Search for one-way flight options from Buffalo to Panama. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:08 pm
BUF
- PTY
3 stops26h 07m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:32 pm
BUF
- PTY
3 stops26h 43m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:18 pm
BUF
- PTY
3 stops26h 57m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:02 pm
BUF
- PTY
2 stops21h 12m
United Airlines
Deal found 4/11![United Airlines logo]()
$302
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:52 pm
BUF
- PTY
2 stops23h 20m
United Airlines
Deal found 4/8![United Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:56 pm
BUF
- PTY
3 stops27h 04m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:11 pm
BUF
- PTY
3 stops22h 19m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:32 pm
BUF
- PTY
3 stops26h 43m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:56 pm
BUF
- PTY
3 stops20h 19m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
BUF
- PTY
1 stop8h 09m
Delta
Deal found 4/8![Delta logo]()
$478
Find flight deals from Buffalo to Panama
Keep the following information in mind while searching for Buffalo to Panama flight deals. Data was last updated April 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $570 (Expedia) |
One-way from | $249 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Buffalo to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 6/2
6:15 am-12:50 pm
1 stop7h 35m
Panama City Tocumen Intl
Wed 6/10
2:24 pm-11:59 pm
1 stop8h 35m
$623
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Sat 5/23
6:05 am-10:30 am
2 stops29h 25m
Panama City Tocumen Intl
Sat 5/30
5:30 am-8:58 am
2 stops26h 28m
$635
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 5/19
3:04 pm-12:46 pm
2 stops22h 42m
Panama City Tocumen Intl
Sat 5/23
1:14 pm-12:04 pm
2 stops21h 50m
$653
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Fri 7/10
7:00 pm-4:04 am
1 stop10h 04m
Panama City Tocumen Intl
Mon 7/13
10:55 pm-8:41 pm
2 stops20h 46m
$660
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Wed 5/27
10:34 am-7:31 pm
1 stop9h 57m
Panama City Tocumen Intl
Wed 6/3
7:55 am-9:51 am
2 stops24h 56m
$660
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 6/2
7:52 pm-7:31 pm
2 stops24h 39m
Panama City Tocumen Intl
Wed 6/10
7:55 am-9:03 pm
2 stops12h 08m
$661
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Tue 5/26
6:15 am-12:50 pm
1 stop7h 35m
Panama City Tocumen Intl
Wed 6/3
2:15 pm-11:59 pm
1 stop8h 44m
$663
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Wed 4/29
6:00 am-1:02 pm
1 stop8h 02m
Panama City Tocumen Intl
Mon 5/11
2:15 pm-11:59 pm
1 stop8h 44m
$666
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Sat 5/9
7:00 am-6:37 pm
2 stops12h 37m
Panama City Tocumen Intl
Sat 5/16
7:55 am-9:53 am
2 stops24h 58m
$673
Cheapest one-way
BuffaloPanama City
BUF - PTY
BUFPTY
Buffalo
Sat 5/2
6:00 am-1:02 pm
1 stop8h 02m
$302
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Buffalo to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Buffalo with our price prediction graph.
BUF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Panama
BUF-PA0
BUF-PTY
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 12, 2026.
Read through reviews of airlines operating flights from Buffalo to Panama, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Crew
8.5
Food
7.2
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Buffalo to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to Panama by cabin class
Find flights from Buffalo to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and Panama flights
Browse other Buffalo and Panama flight options. Last updated on April 12, 2026.
Popular flight searches
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Top airline flying from Buffalo to Panama
Discover the top airline that operate flights from Buffalo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$517 | Average$671 | FlexibilityNo cancel fee | On-timeN/A |