$344+ Cheap flights from Syracuse (SYR) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Sep 23 — Sep 301
Round-trip
1 adult, Economy
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Find cheap flights from Syracuse to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Syracuse to PanamaExplore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
Explore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop7h 59m
Wed 10/282:24 pm -
1 stop8h 31m
Deal found 8/21![Delta logo]()
$713
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:41 pm -
2 stops19h 21m
Wed 10/282:02 pm -
2 stops19h 59m
Deal found 8/21![American Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:44 pm -
2 stops18h 18m
Tue 10/132:02 pm -
2 stops20h 25m
Deal found 8/22![American Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
1 stop7h 59m
Tue 10/132:24 pm -
1 stop8h 31m
Deal found 8/22![Delta logo]()
$753
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:53 pm -
2 stops23h 44m
Tue 10/133:30 pm -
2 stops28h 27m
Deal found 8/22![United Airlines logo]()
$758
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
2 stops32h 45m
Fri 11/68:55 am -
2 stops25h 50m
Deal found 8/19![United Airlines logo]()
$768
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am -
1 stop7h 48m
Thu 9/242:23 pm -
1 stop8h 35m
Deal found 8/19![Delta logo]()
$783
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:40 pm -
2 stops20h 36m
Thu 9/241:16 pm -
2 stops22h 08m
Deal found 8/19![American Airlines logo]()
$787
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:50 pm -
2 stops26h 41m
Sat 10/103:30 pm -
2 stops28h 27m
Deal found 8/19![United Airlines logo]()
$797
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:44 pm -
2 stops18h 18m
Sun 10/112:02 pm -
2 stops19h 59m
Deal found 8/21![American Airlines logo]()
$802
This Expedia deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
2 stops29h 30m
Sun 10/1111:25 am -
3 stops35h 28m
Deal found 8/20![Multiple Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:10 am -
1 stop7h 48m
Sun 10/112:24 pm -
1 stop8h 31m
Deal found 8/21![Delta logo]()
$813
Best flights from Syracuse to PanamaDiscover carefully curated flight deals from Syracuse to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
Discover carefully curated flight deals from Syracuse to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop7h 59m
Wed 10/282:24 pm -
1 stop8h 31m
Deal found 8/21![Delta logo]()
$713
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
2 stops32h 45m
Fri 11/68:55 am -
2 stops25h 50m
Deal found 8/19![United Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:40 pm -
2 stops20h 36m
Thu 9/241:16 pm -
2 stops22h 08m
Deal found 8/19![American Airlines logo]()
$787
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am -
1 stop7h 48m
Thu 9/242:23 pm -
1 stop8h 35m
Deal found 8/19![Delta logo]()
$783
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:40 pm -
2 stops20h 36m
Fri 9/251:16 pm -
2 stops19h 53m
Deal found 8/20![American Airlines logo]()
$787
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:50 pm -
2 stops26h 41m
Sat 10/103:30 pm -
2 stops28h 27m
Deal found 8/19![United Airlines logo]()
$797
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am -
1 stop7h 48m
Fri 9/252:23 pm -
1 stop8h 35m
Deal found 8/20![Delta logo]()
$813
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:10 am -
1 stop7h 48m
Sun 10/112:24 pm -
1 stop8h 31m
Deal found 8/21![Delta logo]()
$813
Last-minute flights from Syracuse to PanamaDiscover last-minute flight deals from Syracuse to Panama. Data last updated August 24, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Panama. Data last updated August 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:29 pm -
2 stops17h 10m
Sat 8/291:39 pm -
2 stops21h 09m
Deal found 8/23![American Airlines logo]()
$883
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:10 am -
1 stop7h 45m
Sat 8/292:30 pm -
1 stop8h 28m
Deal found 8/23![Delta logo]()
$946
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:10 am -
2 stops13h 19m
Sat 8/2912:03 pm -
1 stop21h 03m
Deal found 8/23![Multiple Airlines logo]()
$1,416
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:10 am -
1 stop7h 48m
Sat 9/192:23 pm -
1 stop8h 35m
Deal found 8/21![Delta logo]()
$833
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:44 pm -
2 stops17h 32m
Sat 9/191:16 pm -
2 stops21h 19m
Deal found 8/21![American Airlines logo]()
$837
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am -
1 stop7h 48m
Thu 9/242:23 pm -
1 stop8h 35m
Deal found 8/19![Delta logo]()
$783
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:40 pm -
2 stops20h 36m
Thu 9/241:16 pm -
2 stops22h 08m
Deal found 8/19![American Airlines logo]()
$787
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am -
1 stop7h 48m
Fri 9/252:23 pm -
1 stop8h 35m
Deal found 8/20![Delta logo]()
$813
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:24 pm -
2 stops33h 07m
Thu 9/249:12 am -
1 stop8h 37m
Deal found 8/19![Multiple Airlines logo]()
$1,378
This Travelocity deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
2 stops44h 55m
Fri 9/2511:25 am -
3 stops35h 34m
Deal found 8/20![Multiple Airlines logo]()
$1,451
One-way flights from Syracuse to PanamaSearch for one-way flight options from Syracuse to Panama. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
Search for one-way flight options from Syracuse to Panama. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops14h 31m
Deal found 8/19![United Airlines logo]()
$344
Find flight deals from Syracuse to Panama
Keep the following information in mind while searching for Syracuse to Panama flight deals. Data was last updated August 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $713 (Delta) |
One-way from | $344 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Wed 10/14
6:00 am-12:59 pm
1 stop7h 59m
Panama City Tocumen Intl
Wed 10/28
2:24 pm-11:55 pm
1 stop8h 31m
$713
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Tue 11/3
6:00 am-2:45 pm
2 stops32h 45m
Panama City Tocumen Intl
Fri 11/6
8:55 am-10:45 am
2 stops25h 50m
$768
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Fri 9/18
6:10 am-12:58 pm
1 stop7h 48m
Panama City Tocumen Intl
Thu 9/24
2:23 pm-11:58 pm
1 stop8h 35m
$783
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Fri 9/18
4:40 pm-12:16 pm
2 stops20h 36m
Panama City Tocumen Intl
Thu 9/24
1:16 pm-12:24 pm
2 stops22h 08m
$787
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Fri 9/18
4:40 pm-12:16 pm
2 stops20h 36m
Panama City Tocumen Intl
Fri 9/25
1:16 pm-10:09 am
2 stops19h 53m
$787
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sat 10/3
5:50 pm-7:31 pm
2 stops26h 41m
Panama City Tocumen Intl
Sat 10/10
3:30 pm-8:57 pm
2 stops28h 27m
$797
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Fri 9/18
6:10 am-12:58 pm
1 stop7h 48m
Panama City Tocumen Intl
Fri 9/25
2:23 pm-11:58 pm
1 stop8h 35m
$813
Quickest round-trip
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Sun 10/4
6:10 am-12:58 pm
1 stop7h 48m
Panama City Tocumen Intl
Sun 10/11
2:24 pm-11:55 pm
1 stop8h 31m
$813
Cheapest one-way
Quickest one-way
SyracusePanama City
SYR Syracuse Hancock Intl - PTY Panama City Tocumen Intl
SYRPTY
Syracuse Hancock Intl
Wed 10/7
6:00 am-7:31 pm
2 stops14h 31m
$344
Sorted by cheapest first
Best time to book a flight from Syracuse to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Syracuse with our price prediction graph.
SYR-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to Panama
SYR-PA0
SYR-PTY
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 24, 2026.
Read reviews from past customers who have flown Delta from Syracuse to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Syracuse to Panama
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
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Syracuse and Panama flights
Browse other Syracuse and Panama flight options. Last updated on August 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Syracuse to Panama
Discover the top airline that operate flights from Syracuse to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$517 | Average$948 | FlexibilityNo cancel fee | On-timeN/A |