Panama

$627+ Cheap flights from Syracuse (SYR) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
May 12 — May 191
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Cheap flight deals from Syracuse to Panama

Cheapest flights from Syracuse to Panama
Explore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.

This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:48 am
SYR
-
PTY
2 stops9h 22m
American Airlines
Fri 10/23:40 pm
PTY
-
SYR
2 stops23h 23m
American Airlines
Deal found 4/10$627
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:43 pm
SYR
-
PTY
2 stops17h 31m
American Airlines
Sat 8/83:20 pm
PTY
-
SYR
2 stops18h 59m
American Airlines
Deal found 4/7$640
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:00 am
SYR
-
PTY
1 stop7h 56m
Delta
Sat 9/192:21 pm
PTY
-
SYR
1 stop8h 37m
Delta
Deal found 4/11$653
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:33 pm
SYR
-
PTY
2 stops23h 34m
United Airlines
Fri 12/411:55 pm
PTY
-
SYR
2 stops17h 02m
United Airlines
Deal found 4/6$660
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am
SYR
-
PTY
1 stop7h 56m
Delta
Mon 10/192:21 pm
PTY
-
SYR
1 stop8h 34m
Delta
Deal found 4/10$663
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:41 pm
SYR
-
PTY
2 stops17h 33m
American Airlines
Mon 6/11:14 pm
PTY
-
SYR
2 stops20h 08m
American Airlines
Deal found 4/10$670
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:38 pm
SYR
-
PTY
2 stops21h 32m
American Airlines
Sat 9/193:40 pm
PTY
-
SYR
2 stops19h 20m
American Airlines
Deal found 4/11$673
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
SYR
-
PTY
1 stop7h 56m
Delta
Sat 9/192:21 pm
PTY
-
SYR
1 stop8h 37m
Delta
Deal found 4/11$676
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:33 pm
SYR
-
PTY
2 stops21h 41m
United Airlines
Wed 10/219:45 am
PTY
-
SYR
2 stops12h 48m
United Airlines
Deal found 4/10$687
This KAYAK deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am
SYR
-
PTY
1 stop7h 56m
LATAM Airlines
Tue 10/202:21 pm
PTY
-
SYR
1 stop8h 34m
LATAM Airlines
Deal found 4/10$693

Find flight deals from Syracuse to Panama

Keep the following information in mind while searching for Syracuse to Panama flight deals. Data was last updated April 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$627
(American Airlines)

Popular in

February

Cheapest in

October

Average price

$698
Provider with most accurate pricing for Syracuse Hancock Intl-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Panama City Tocumen Intl flights.
From Syracuse Hancock Intl to Panama
Highest demand for flights based on searches. 22% potential increase in price ($193 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($31 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 9/14

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sat 9/19

2:21 pm-11:58 pm

1 stop8h 37m

$653

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 5/25

7:41 pm-12:14 pm

2 stops17h 33m

Panama City Tocumen Intl

Mon 6/1

1:14 pm-10:22 am

2 stops20h 08m

$670

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 9/13

5:38 pm-2:10 pm

2 stops21h 32m

Panama City Tocumen Intl

Sat 9/19

3:40 pm-12:00 pm

2 stops19h 20m

$673

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 9/18

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Fri 10/2

2:21 pm-11:58 pm

1 stop8h 37m

$676

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 5/24

6:15 am-4:04 am

2 stops22h 49m

Panama City Tocumen Intl

Sun 5/31

10:55 pm-4:48 pm

2 stops16h 53m

$718

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 5/21

5:44 pm-6:37 pm

2 stops25h 53m

Panama City Tocumen Intl

Thu 5/28

10:00 am-9:55 am

2 stops22h 55m

$770

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 5/23

6:00 am-7:31 pm

2 stops14h 31m

Panama City Tocumen Intl

Sat 5/30

7:55 am-9:55 am

2 stops25h 00m

$783

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 9/18

6:00 am-2:55 pm

3 stops33h 55m

Panama City Tocumen Intl

Fri 10/2

3:50 pm-11:53 pm

2 stops31h 03m

$810
Quickest round-trip

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 5/25

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Mon 6/1

2:15 pm-11:52 pm

1 stop8h 37m

$833

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 5/24

6:00 am-2:55 pm

3 stops33h 55m

Panama City Tocumen Intl

Sun 5/31

3:50 pm-11:57 pm

2 stops31h 07m

$914

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/11

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Syracuse to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama

What is the cheapest month to book a flight from Syracuse to Panama?

Currently, July is the cheapest month in which you can book a flight from Syracuse to Panama (average of $375). Flying from Syracuse to Panama in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 12, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Syracuse to Panama?

    If you book a flight to Panama from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Panama?

    For as low as $653, Delta can have you in Panama from Syracuse in 7h 56m. Syracuse and Panama are separated by a distance of 2359 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Syracuse to Panama that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama.

  • Can I find deals for business class flights from Syracuse to Panama?

    Yes. Cheapflights offers flight deals from Syracuse to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama?

    Currently, July is the cheapest month in which you can book a flight from Syracuse to Panama (average of $375). Flying from Syracuse to Panama in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Syracuse to Panama

Discover the top 2 airlines that operate flights from Syracuse to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$308Average$623FlexibilityNo cancel feeOn-time69%
DeltaCheapest$497Average$555FlexibilityNo cancel feeOn-timeN/A

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