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$633+ Cheap flights from Syracuse (SYR) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Jun 23 — Jun 301
Tue 6/23
Tue 6/30
1 adult, Economy
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Cheap flight deals from Syracuse to Panama

Cheapest flights from Syracuse to Panama
Explore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.

This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
SYR
-
PTY
1 stop8h 13m
Delta
Tue 9/152:21 pm
PTY
-
SYR
1 stop8h 37m
Delta
Deal found 5/20$633
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:10 am
SYR
-
PTY
2 stops14h 21m
United Airlines
Tue 9/159:45 am
PTY
-
SYR
2 stops23h 41m
United Airlines
Deal found 5/20$637
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:46 pm
SYR
-
PTY
2 stops22h 14m
American Airlines
Tue 10/273:35 pm
PTY
-
SYR
2 stops18h 09m
American Airlines
Deal found 5/24$677
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
SYR
-
PTY
1 stop8h 05m
Delta
Sat 8/82:30 pm
PTY
-
SYR
1 stop8h 28m
Delta
Deal found 5/22$683
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:05 am
SYR
-
PTY
1 stop8h 04m
Delta
Mon 6/222:24 pm
PTY
-
SYR
1 stop8h 35m
Delta
Deal found 5/20$686
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:15 am
SYR
-
PTY
2 stops22h 49m
United Airlines
Sat 8/810:00 am
PTY
-
SYR
2 stops22h 55m
United Airlines
Deal found 5/22$687
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
SYR
-
PTY
1 stop7h 56m
Delta
Sat 9/192:21 pm
PTY
-
SYR
1 stop8h 37m
Delta
Deal found 5/20$693
This Expedia deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:00 am
SYR
-
PTY
2 stops39h 35m
Multiple Airlines
Sun 6/74:25 am
PTY
-
SYR
2 stops27h 39m
Multiple Airlines
Deal found 5/21$708
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/134:21 pm
SYR
-
PTY
2 stops20h 54m
American Airlines
Sat 9/191:16 pm
PTY
-
SYR
2 stops20h 53m
American Airlines
Deal found 5/24$717

Find flight deals from Syracuse to Panama

Keep the following information in mind while searching for Syracuse to Panama flight deals. Data was last updated May 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$633
(Delta)

Popular in

June

Cheapest in

October

Average price

$765
Provider with most accurate pricing for Syracuse Hancock Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Panama City Tocumen Intl flights.
Search Deals
From Syracuse Hancock Intl to Panama
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($141 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 9/9

6:00 am-1:13 pm

1 stop8h 13m

Panama City Tocumen Intl

Tue 9/15

2:21 pm-11:58 pm

1 stop8h 37m

$633

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 9/9

6:10 am-7:31 pm

2 stops14h 21m

Panama City Tocumen Intl

Tue 9/15

9:45 am-10:26 am

2 stops23h 41m

$637

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 7/8

6:00 am-4:04 am

2 stops23h 04m

Panama City Tocumen Intl

Tue 7/14

10:55 pm-9:09 pm

2 stops21h 14m

$677
Quickest round-trip

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Tue 7/28

6:00 am-1:05 pm

1 stop8h 05m

Panama City Tocumen Intl

Sat 8/8

2:30 pm-11:58 pm

1 stop8h 28m

$683

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Tue 7/28

6:15 am-4:04 am

2 stops22h 49m

Panama City Tocumen Intl

Sat 8/8

10:00 am-9:55 am

2 stops22h 55m

$687

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 9/13

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sat 9/19

2:21 pm-11:58 pm

1 stop8h 37m

$693

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/20

Sorted by cheapest first

Best time to book a flight from Syracuse to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 24, 2026.
Read reviews from past customers who have flown Delta from Syracuse to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,437 reviews

Comfort

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.8

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
Delta
7.9
Good
8,437 reviews
Delta
7.9
Good
8,437 reviews

Comfort

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.8

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Panama?

    If you book a flight to Panama from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Panama?

    For as low as $633, Delta can have you in Panama from Syracuse in 8h 13m. Syracuse and Panama are separated by a distance of 2359 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Syracuse to Panama that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama.

  • Can I find deals for business class flights from Syracuse to Panama?

    Yes. Cheapflights offers flight deals from Syracuse to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Syracuse to Panama

Discover the top airline that operate flights from Syracuse to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$507Average$628FlexibilityNo cancel feeOn-timeN/A

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