$611+ Cheap flights from Roanoke (ROA) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Panama City
Cheapest
Best
Last-minute
Cheapest flights from Roanoke to Panama CityExplore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:09 pm -
2 stops20h 07m
Fri 10/21:16 pm -
2 stops21h 27m
Deal found 9/7![American Airlines logo]()
$735
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 58m
Fri 10/22:23 pm -
1 stop8h 36m
Deal found 9/7![Delta logo]()
$855
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:05 pm -
2 stops19h 09m
Fri 10/169:45 am -
2 stops23h 12m
Deal found 9/9![United Airlines logo]()
$988
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:18 pm -
2 stops24h 16m
Sat 11/283:34 pm -
2 stops21h 02m
Deal found 9/10![American Airlines logo]()
$1,002
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop8h 02m
Sat 11/283:29 pm -
1 stop8h 52m
Deal found 9/10![Delta logo]()
$1,091
This BusinessClass deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:26 am -
1 stop10h 09m
Sat 11/289:11 am -
1 stop9h 56m
Deal found 9/10![Copa Airlines logo]()
$3,887
Best flights from Roanoke to Panama CityDiscover carefully curated flight deals from Roanoke to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Roanoke to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/264:10 pm -
2 stops21h 26m
Thu 2/42:36 pm -
2 stops21h 21m
Deal found 9/6![American Airlines logo]()
$611
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:00 am -
1 stop7h 55m
Thu 2/43:20 pm -
1 stop9h 03m
Deal found 9/6![Delta logo]()
$795
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:05 pm -
2 stops19h 09m
Fri 10/169:45 am -
2 stops23h 12m
Deal found 9/8![United Airlines logo]()
$988
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:09 pm -
2 stops20h 07m
Fri 10/21:16 pm -
2 stops21h 27m
Deal found 9/7![American Airlines logo]()
$735
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 58m
Fri 10/22:23 pm -
1 stop8h 36m
Deal found 9/7![Delta logo]()
$855
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:18 pm -
2 stops24h 16m
Sat 11/283:34 pm -
2 stops21h 02m
Deal found 9/10![American Airlines logo]()
$1,002
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop8h 02m
Sat 11/283:29 pm -
1 stop8h 52m
Deal found 9/10![Delta logo]()
$1,091
Last-minute flights from Roanoke to Panama CityDiscover last-minute flight deals from Roanoke to Panama City. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Panama City. Data last updated September 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:09 pm -
2 stops20h 07m
Fri 10/21:16 pm -
2 stops21h 27m
Deal found 9/7![American Airlines logo]()
$735
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 58m
Fri 10/22:23 pm -
1 stop8h 36m
Deal found 9/7![Delta logo]()
$855
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:05 pm -
2 stops19h 09m
Fri 10/169:45 am -
2 stops23h 12m
Deal found 9/9![United Airlines logo]()
$988
Find flight deals from Roanoke to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $611 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Tue 1/26
4:10 pm-1:36 pm
2 stops21h 26m
Panama City Tocumen Intl
Thu 2/4
2:36 pm-11:57 am
2 stops21h 21m
$611
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 9/25
5:09 pm-12:16 pm
2 stops20h 07m
Panama City Tocumen Intl
Fri 10/2
1:16 pm-11:43 am
2 stops21h 27m
$735
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Tue 1/26
6:00 am-1:55 pm
1 stop7h 55m
Panama City Tocumen Intl
Thu 2/4
3:20 pm-12:23 am
1 stop9h 03m
$795
Quickest round-trip
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 9/25
6:00 am-12:58 pm
1 stop7h 58m
Panama City Tocumen Intl
Fri 10/2
2:23 pm-11:59 pm
1 stop8h 36m
$855
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Mon 10/12
8:05 pm-2:14 pm
2 stops19h 09m
Panama City Tocumen Intl
Fri 10/16
9:45 am-9:57 am
2 stops23h 12m
$988
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Sat 11/21
2:18 pm-2:34 pm
2 stops24h 16m
Panama City Tocumen Intl
Sat 11/28
3:34 pm-12:36 pm
2 stops21h 02m
$1,002
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Sat 11/21
6:00 am-2:02 pm
1 stop8h 02m
Panama City Tocumen Intl
Sat 11/28
3:29 pm-12:21 am
1 stop8h 52m
$1,091
Sorted by cheapest first
Compare providers for flights from Roanoke to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
ROA-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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