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Panama City

$441+ Cheap flights from Roanoke (ROA) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$441
(United Airlines)
Provider with most accurate pricing for Roanoke-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Panama City Tocumen Intl flights.
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From Roanoke to Panama City Tocumen Intl
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Find flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:45 amROA - PTY
2 stops13h 46mUnited Airlines
Mon 4/2710:00 amPTY - ROA
2 stops23h 13mUnited Airlines
Deal found 1/6$441
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 amROA - PTY
2 stops12h 37mUnited Airlines
Wed 10/283:41 pmPTY - ROA
2 stops19h 05mUnited Airlines
Deal found 1/6$461
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 amROA - PTY
1 stop7h 55mDelta
Mon 4/272:20 pmPTY - ROA
1 stop9h 03mDelta
Deal found 1/6$489
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/63:39 pmROA - PTY
2 stops23h 06mUnited Airlines
Tue 2/104:41 pmPTY - ROA
2 stops19h 16mUnited Airlines
Deal found 1/8$501
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/315:39 pmROA - PTY
2 stops23h 28mUnited Airlines
Sun 3/14:41 pmPTY - ROA
2 stops17h 27mUnited Airlines
Deal found 1/7$502
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:47 pmROA - PTY
2 stops26h 20mUnited Airlines
Thu 2/264:41 pmPTY - ROA
2 stops17h 27mUnited Airlines
Deal found 1/8$518
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/216:45 amROA - PTY
2 stops13h 17mUnited Airlines
Sat 1/314:41 pmPTY - ROA
2 stops19h 24mUnited Airlines
Deal found 1/7$522
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/93:39 pmROA - PTY
2 stops25h 28mUnited Airlines
Tue 1/134:41 pmPTY - ROA
2 stops26h 50mUnited Airlines
Deal found 1/8$523
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1310:30 amROA - PTY
2 stops18h 40mUnited Airlines
Tue 3/173:41 pmPTY - ROA
2 stops17h 27mUnited Airlines
Deal found 1/6$528
This Gurufare deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/202:55 pmROA - PTY
2 stops29h 07mCopa Airlines
Thu 1/294:41 pmPTY - ROA
2 stops19h 24mCopa Airlines
Deal found 1/8$534
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:59 pmROA - PTY
2 stops21h 13mUnited Airlines
Sun 4/193:30 pmPTY - ROA
2 stops21h 43mUnited Airlines
Deal found 1/8$538
This Delta deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/206:00 amROA - PTY
1 stop7h 55mDelta
Thu 1/293:20 pmPTY - ROA
1 stop8h 44mDelta
Deal found 1/8$561

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 4/14

6:45 am-7:31 pm

2 stops13h 46m

Panama City Tocumen Intl

Mon 4/27

10:00 am-10:13 am

2 stops23h 13m

$441

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 4/14

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Mon 4/27

2:20 pm-12:23 am

1 stop9h 03m

$489

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Sun 4/19

10:00 am-9:49 am

2 stops22h 49m

$501

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 2/6

3:39 pm-2:45 pm

2 stops23h 06m

Panama City Tocumen Intl

Tue 2/10

4:41 pm-11:57 am

2 stops19h 16m

$501

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 1/31

5:39 pm-5:07 pm

2 stops23h 28m

Panama City Tocumen Intl

Sun 3/1

4:41 pm-8:49 pm

2 stops28h 08m

$502

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 2/19

2:47 pm-5:07 pm

2 stops26h 20m

Panama City Tocumen Intl

Thu 2/26

4:41 pm-10:08 am

2 stops17h 27m

$518

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Wed 1/21

6:45 am-7:38 pm

2 stops12h 53m

Panama City Tocumen Intl

Sat 1/31

4:41 pm-7:31 pm

2 stops26h 50m

$522

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 3/13

10:30 am-4:10 am

2 stops18h 40m

Panama City Tocumen Intl

Tue 3/17

3:41 pm-10:08 am

2 stops17h 27m

$528

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

6:00 am-1:03 pm

1 stop8h 03m

Panama City Tocumen Intl

Sun 4/19

2:20 pm-12:23 am

1 stop9h 03m

$534

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City?

    United Airlines and Delta can get you from Roanoke to Panama City in just under 7h 55m. Your travel time can differ by up to 5h 51m. The distance from Roanoke to Panama City is about 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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