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Panama City

$302+ Cheap flights from Roanoke (ROA) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:00 pm
ROA
-
PTY
2 stops24h 14m
United Airlines
Sun 10/253:41 pm
PTY
-
ROA
2 stops17h 51m
United Airlines
Deal found 4/28$591
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:18 pm
ROA
-
PTY
2 stops20h 28m
American Airlines
Sat 5/161:49 pm
PTY
-
ROA
2 stops17h 47m
American Airlines
Deal found 4/28$673
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:15 am
ROA
-
PTY
2 stops22h 49m
United Airlines
Fri 6/199:45 am
PTY
-
ROA
2 stops22h 57m
United Airlines
Deal found 4/28$687
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am
ROA
-
PTY
1 stop7h 56m
Delta
Sun 10/252:21 pm
PTY
-
ROA
1 stop8h 28m
Delta
Deal found 4/28$719
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:42 pm
ROA
-
PTY
2 stops20h 32m
American Airlines
Mon 6/151:14 pm
PTY
-
ROA
2 stops24h 10m
American Airlines
Deal found 4/24$770
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
ROA
-
PTY
1 stop8h 09m
Delta
Fri 6/192:24 pm
PTY
-
ROA
1 stop9h 08m
Delta
Deal found 4/28$1,009
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:00 am
ROA
-
PTY
1 stop8h 09m
Delta
Mon 6/152:24 pm
PTY
-
ROA
1 stop9h 05m
Delta
Deal found 4/24$1,022
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:40 am
ROA
-
PTY
2 stops12h 57m
United Airlines
Tue 7/2110:55 pm
PTY
-
ROA
2 stops17h 09m
United Airlines
Deal found 4/24$1,025
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
ROA
-
PTY
1 stop7h 50m
Delta
Sat 5/162:15 pm
PTY
-
ROA
1 stop7h 43m
Delta
Deal found 4/28$1,220
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:47 pm
ROA
-
PTY
2 stops26h 44m
United Airlines
Mon 6/157:55 am
PTY
-
ROA
2 stops14h 49m
United Airlines
Deal found 4/24$1,230
This Booking.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:30 am
ROA
-
PTY
2 stops25h 00m
Avianca
Mon 6/1511:25 am
PTY
-
ROA
3 stops25h 35m
Avianca
Deal found 4/24$1,892

Find flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$591
(United Airlines)

One-way from

$302
(American Airlines)
Provider with most accurate pricing for Roanoke-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Panama City Tocumen Intl flights.
Search Deals
From Roanoke to Panama City Tocumen Intl
Search Deals
One-way flight from Roanoke to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 10/22

3:00 pm-2:14 pm

2 stops24h 14m

Panama City Tocumen Intl

Sun 10/25

3:41 pm-10:32 am

2 stops17h 51m

$591

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 10/22

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sun 10/25

2:21 pm-11:49 pm

1 stop8h 28m

$719

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/8

4:42 pm-12:14 pm

2 stops20h 32m

Panama City Tocumen Intl

Mon 6/15

1:14 pm-2:24 pm

2 stops24h 10m

$770
Quickest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 5/14

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Sat 5/16

2:15 pm-10:58 pm

1 stop7h 43m

$1,220

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/8

10:30 am-10:30 am

2 stops25h 00m

Panama City Tocumen Intl

Mon 6/15

11:25 am-2:00 pm

3 stops25h 35m

$1,892

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/8

10:30 am-7:31 pm

2 stops10h 01m

Panama City Tocumen Intl

Mon 6/15

10:29 pm-9:42 am

1 stop10h 13m

$4,673

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 6/12

10:30 am-8:35 pm

1 stop11h 05m

Panama City Tocumen Intl

Fri 6/19

10:29 pm-9:42 am

1 stop10h 13m

$4,725

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 5/14

10:34 am-7:31 pm

2 stops9h 57m

Panama City Tocumen Intl

Sat 5/16

9:13 am-11:44 pm

1 stop13h 31m

$5,574
Cheapest one-way

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 5/4

6:03 pm-12:46 pm

2 stops19h 43m

$302
Quickest one-way

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 5/4

6:00 am-1:02 pm

1 stop8h 02m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City?

    United Airlines, Delta, and American Airlines can get you from Roanoke to Panama City in just under 7h 56m. Your travel time can differ by up to 16h 18m. The distance from Roanoke to Panama City is about 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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