HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$581+ Cheap flights from Roanoke (ROA) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Jul 13 — Jul 201
Mon 7/13
Mon 7/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Roanoke to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.

This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 am
ROA
-
PTY
2 stops22h 49m
United Airlines
Thu 8/273:30 pm
PTY
-
ROA
2 stops17h 39m
United Airlines
Deal found 6/12$581
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am
ROA
-
PTY
1 stop7h 56m
Delta
Sun 9/272:21 pm
PTY
-
ROA
1 stop7h 23m
Delta
Deal found 6/11$607
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:51 pm
ROA
-
PTY
2 stops25h 46m
United Airlines
Sun 9/2710:00 am
PTY
-
ROA
2 stops23h 02m
United Airlines
Deal found 6/11$611
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:15 am
ROA
-
PTY
2 stops22h 49m
United Airlines
Sat 8/810:55 pm
PTY
-
ROA
2 stops23h 49m
United Airlines
Deal found 6/11$641
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:15 am
ROA
-
PTY
2 stops22h 49m
United Airlines
Fri 7/319:45 am
PTY
-
ROA
2 stops22h 57m
United Airlines
Deal found 6/8$651
This KAYAK deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:51 pm
ROA
-
PTY
2 stops25h 46m
Copa Airlines
Sun 9/273:30 pm
PTY
-
ROA
2 stops17h 32m
Copa Airlines
Deal found 6/11$660
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:15 am
ROA
-
PTY
2 stops22h 49m
United Airlines
Sat 7/2510:00 am
PTY
-
ROA
2 stops22h 42m
United Airlines
Deal found 6/9$661
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
ROA
-
PTY
1 stop7h 55m
Delta
Fri 8/212:20 pm
PTY
-
ROA
1 stop9h 07m
Delta
Deal found 6/9$677
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 pm
ROA
-
PTY
2 stops19h 36m
American Airlines
Thu 11/192:43 pm
PTY
-
ROA
2 stops17h 47m
American Airlines
Deal found 6/10$707
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
ROA
-
PTY
1 stop8h 05m
Delta
Fri 7/312:24 pm
PTY
-
ROA
1 stop9h 01m
Delta
Deal found 6/8$757
This oojo deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:30 am
ROA
-
PTY
3 stops29h 25m
Avianca
Sat 8/14:25 am
PTY
-
ROA
2 stops18h 19m
Avianca
Deal found 6/10$1,470
This Avianca deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:05 pm
ROA
-
PTY
2 stops15h 25m
Avianca
Thu 8/2711:25 am
PTY
-
ROA
3 stops30h 42m
Avianca
Deal found 6/12$1,823

Find flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$581
(United Airlines)
Provider with most accurate pricing for Roanoke-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Panama City Tocumen Intl flights.
Search Deals
From Roanoke to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 8/24

6:15 am-4:04 am

2 stops22h 49m

Panama City Tocumen Intl

Thu 8/27

3:30 pm-10:09 am

2 stops17h 39m

$581
Quickest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sun 11/15

6:00 am-2:05 pm

1 stop8h 05m

Panama City Tocumen Intl

Thu 11/19

3:30 pm-12:23 am

1 stop8h 53m

$607

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Wed 9/23

5:51 pm-6:37 pm

2 stops25h 46m

Panama City Tocumen Intl

Sun 9/27

10:00 am-10:02 am

2 stops23h 02m

$611

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 8/14

8:05 pm-6:37 pm

2 stops23h 32m

Panama City Tocumen Intl

Fri 8/21

3:30 pm-9:41 am

2 stops17h 11m

$641

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sun 8/2

6:15 am-4:04 am

2 stops22h 49m

Panama City Tocumen Intl

Sat 8/8

10:55 pm-11:44 pm

2 stops23h 49m

$641

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 7/24

6:15 am-4:04 am

2 stops22h 49m

Panama City Tocumen Intl

Fri 7/31

9:45 am-9:42 am

2 stops22h 57m

$651

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 7/18

6:15 am-4:04 am

2 stops22h 49m

Panama City Tocumen Intl

Sat 7/25

10:00 am-9:42 am

2 stops22h 42m

$661

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 7/25

6:40 am-4:04 am

2 stops22h 24m

Panama City Tocumen Intl

Sat 8/1

10:55 pm-11:44 pm

2 stops23h 49m

$661

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 8/24

8:05 pm-10:30 am

2 stops15h 25m

Panama City Tocumen Intl

Thu 8/27

11:25 am-7:07 pm

3 stops30h 42m

$1,823

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sun 8/2

5:00 am-12:14 pm

2 stops8h 14m

Panama City Tocumen Intl

Sat 8/8

1:39 pm-8:31 am

3 stops17h 52m

$2,400

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City?

    United Airlines can get you from Roanoke to Panama City in just under 22h 49m. Your travel time can differ by up to . The distance from Roanoke to Panama City is about 1951 mi.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.