$796+ Cheap flights from Roanoke (ROA) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Nov 27 — Dec 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Roanoke to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Panama City
Cheapest
Best
Last-minute
Cheapest flights from Roanoke to Panama CityExplore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2026.
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:51 pm -
2 stops25h 47m
Sun 11/154:41 pm -
2 stops16h 45m
Deal found 10/27![United Airlines logo]()
$796
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
2 stops13h 08m
Sun 11/14:41 pm -
2 stops16h 45m
Deal found 10/27![United Airlines logo]()
$830
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop7h 59m
Sun 11/83:24 pm -
1 stop9h 03m
Deal found 10/24![Delta logo]()
$857
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 pm -
2 stops30h 10m
Fri 11/65:30 am -
2 stops13h 37m
Deal found 10/27![Avianca logo]()
$867
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:51 pm -
2 stops16h 19m
Sat 10/315:30 am -
2 stops12h 37m
Deal found 10/26![Multiple Airlines logo]()
$895
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:55 pm -
2 stops12h 15m
Sat 10/315:30 am -
2 stops12h 37m
Deal found 10/26![Multiple Airlines logo]()
$919
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:51 pm -
2 stops26h 11m
Sat 11/2810:00 am -
2 stops23h 51m
Deal found 10/26![United Airlines logo]()
$1,305
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop7h 59m
Sun 11/153:29 pm -
1 stop8h 50m
Deal found 10/27![Delta logo]()
$1,845
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop8h 04m
Sat 11/283:31 pm -
1 stop8h 50m
Deal found 10/26![Delta logo]()
$2,362
This Ovago deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
2 stops13h 08m
Sun 11/110:29 pm -
1 stop11h 22m
Deal found 10/27![Copa Airlines logo]()
$2,955
Best flights from Roanoke to Panama CityDiscover carefully curated flight deals from Roanoke to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2026.
Discover carefully curated flight deals from Roanoke to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2026.
This BusinessClass deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/197:06 pm -
2 stops20h 52m
Sun 3/283:24 pm -
2 stops28h 53m
Deal found 10/26![GOL logo]()
$861
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:51 pm -
2 stops26h 11m
Sat 11/2810:00 am -
2 stops23h 51m
Deal found 10/26![United Airlines logo]()
$1,305
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop8h 04m
Sat 11/283:31 pm -
1 stop8h 50m
Deal found 10/26![Delta logo]()
$2,362
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/196:30 am -
2 stops8h 54m
Sun 3/283:24 pm -
3 stops17h 19m
Deal found 10/26![American Airlines logo]()
$3,131
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/195:00 am -
2 stops8h 25m
Sun 3/289:20 am -
1 stop8h 18m
Deal found 10/26![Multiple Airlines logo]()
$5,389
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/196:00 am -
1 stop8h 00m
Sun 3/282:25 pm -
1 stop8h 58m
Deal found 10/26![Delta logo]()
$2,803
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/198:00 pm -
1 stop11h 03m
Sun 3/289:20 am -
1 stop8h 18m
Deal found 10/26![United Airlines logo]()
$4,785
Last-minute flights from Roanoke to Panama CityDiscover last-minute flight deals from Roanoke to Panama City. Data last updated October 28, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Panama City. Data last updated October 28, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:55 pm -
2 stops12h 15m
Sat 10/315:30 am -
2 stops12h 37m
Deal found 10/26![Multiple Airlines logo]()
$919
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
2 stops13h 08m
Sun 11/14:41 pm -
2 stops16h 45m
Deal found 10/27![United Airlines logo]()
$830
This Ovago deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
2 stops13h 08m
Sun 11/110:29 pm -
1 stop11h 22m
Deal found 10/27![Copa Airlines logo]()
$2,955
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:07 am -
2 stops8h 55m
Sun 11/13:13 pm -
3 stops18h 30m
Deal found 10/27![American Airlines logo]()
$3,192
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:51 pm -
2 stops25h 47m
Sun 11/154:41 pm -
2 stops16h 45m
Deal found 10/27![United Airlines logo]()
$796
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop7h 59m
Sun 11/153:29 pm -
1 stop8h 50m
Deal found 10/27![Delta logo]()
$1,845
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:01 am -
2 stops9h 12m
Sun 11/153:13 pm -
3 stops18h 30m
Deal found 10/27![American Airlines logo]()
$3,185
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 pm -
2 stops30h 10m
Fri 11/65:30 am -
2 stops13h 37m
Deal found 10/27![Avianca logo]()
$867
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:51 pm -
2 stops26h 11m
Sat 11/2810:00 am -
2 stops23h 51m
Deal found 10/26![United Airlines logo]()
$1,305
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop8h 04m
Sat 11/283:31 pm -
1 stop8h 50m
Deal found 10/26![Delta logo]()
$2,362
Find flight deals from Roanoke to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $677 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 28, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 3/19
7:06 pm-2:58 pm
2 stops20h 52m
Panama City Tocumen Intl
Sun 3/28
3:24 pm-9:17 pm
2 stops28h 53m
$861
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Wed 11/25
5:51 pm-8:02 pm
2 stops26h 11m
Panama City Tocumen Intl
Sat 11/28
10:00 am-9:51 am
2 stops23h 51m
$1,305
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Wed 11/25
6:00 am-2:04 pm
1 stop8h 04m
Panama City Tocumen Intl
Sat 11/28
3:31 pm-12:21 am
1 stop8h 50m
$2,362
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 3/19
6:00 am-1:00 pm
1 stop8h 00m
Panama City Tocumen Intl
Sun 3/28
2:25 pm-12:23 am
1 stop8h 58m
$2,803
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 3/19
6:30 am-2:24 pm
2 stops8h 54m
Panama City Tocumen Intl
Sun 3/28
3:24 pm-9:43 am
3 stops17h 19m
$3,131
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 3/19
8:00 pm-6:03 am
1 stop11h 03m
Panama City Tocumen Intl
Sun 3/28
9:20 am-6:38 pm
1 stop8h 18m
$4,785
Quickest round-trip
RoanokePanama City
ROA Roanoke - PTY Panama City Tocumen Intl
ROAPTY
Roanoke
Fri 3/19
5:00 am-12:25 pm
2 stops8h 25m
Panama City Tocumen Intl
Sun 3/28
9:20 am-6:38 pm
1 stop8h 18m
$5,389
Sorted by cheapest first
Compare providers for flights from Roanoke to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
ROA-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Roanoke
Panama City flight routes
Popular flights